Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with Target = 'Disintegrin and metalloproteinase domain-containing protein 8'
LigandChemical structure of BindingDB Monomer ID 50441212BDBM50441212(CHEMBL2431028)
Affinity DataIC50: 12nMAssay Description:Inhibition of human recombinant ADAM8 using PepDAB13 as substrate preincubated with enzyme for 45 mins followed by substrate addition and measured fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50421688BDBM50421688(CHEMBL5267938)
Affinity DataIC50: 41nMAssay Description:Inhibition of human recombinant ADAM8 using PepDAB13 as substrate preincubated with enzyme for 45 mins followed by substrate addition and measured fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50421689BDBM50421689(CHEMBL5283335)
Affinity DataIC50: 73nMAssay Description:Inhibition of human recombinant ADAM8 using PepDAB13 as substrate preincubated with enzyme for 45 mins followed by substrate addition and measured fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50441212BDBM50441212(CHEMBL2431028)
Affinity DataIC50: 120nMAssay Description:Inhibition of ADAM8 (unknown origin) expressed in HEK293 cells assessed as inhibition of CD23 shedding by measuring reduction of soluble CD23 release...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50190577BDBM50190577(CHEMBL3828456)
Affinity DataIC50: 142nMAssay Description:Inhibition of ADAM8 (unknown origin) expressed in African green monkey COS7 cells co-expressing CD23 assessed as inhibition of CD23 shedding after 6 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2017
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50190506BDBM50190506(CHEMBL3828497)
Affinity DataIC50: 157nMAssay Description:Inhibition of ADAM8 (unknown origin) expressed in African green monkey COS7 cells co-expressing CD23 assessed as inhibition of CD23 shedding after 6 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2017
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50190504BDBM50190504(CHEMBL3827850)
Affinity DataIC50: 182nMAssay Description:Inhibition of recombinant ADAM8 (unknown origin) expressed in African green monkey COS7 cells co-expressing CD23 assessed as inhibition of CD23 shedd...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2017
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50190575BDBM50190575(CHEMBL3827732)
Affinity DataIC50: 192nMAssay Description:Inhibition of ADAM8 (unknown origin) expressed in African green monkey COS7 cells co-expressing CD23 assessed as inhibition of CD23 shedding after 6 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2017
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50190527BDBM50190527(CHEMBL3827980)
Affinity DataIC50: 220nMAssay Description:Inhibition of ADAM8 (unknown origin) expressed in African green monkey COS7 cells co-expressing CD23 assessed as inhibition of CD23 shedding after 6 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2017
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50190505BDBM50190505(CHEMBL3827893)
Affinity DataIC50: 240nMAssay Description:Inhibition of ADAM8 (unknown origin) expressed in African green monkey COS7 cells co-expressing CD23 assessed as inhibition of CD23 shedding after 6 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2017
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50190511BDBM50190511(CHEMBL3827446)
Affinity DataIC50: 256nMAssay Description:Inhibition of ADAM8 (unknown origin) expressed in African green monkey COS7 cells co-expressing CD23 assessed as inhibition of CD23 shedding after 6 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2017
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50421689BDBM50421689(CHEMBL5283335)
Affinity DataIC50: 350nMAssay Description:Inhibition of ADAM8 (unknown origin) expressed in HEK293 cells assessed as inhibition of CD23 shedding by measuring reduction of soluble CD23 release...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50190576BDBM50190576(CHEMBL3827091)
Affinity DataIC50: 368nMAssay Description:Inhibition of ADAM8 (unknown origin) expressed in African green monkey COS7 cells co-expressing CD23 assessed as inhibition of CD23 shedding after 6 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2017
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50190538BDBM50190538(CHEMBL3827647)
Affinity DataIC50: 378nMAssay Description:Inhibition of ADAM8 (unknown origin) expressed in African green monkey COS7 cells co-expressing CD23 assessed as inhibition of CD23 shedding after 6 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2017
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50190508BDBM50190508(CHEMBL3828432)
Affinity DataIC50: 420nMAssay Description:Inhibition of ADAM8 (unknown origin) expressed in African green monkey COS7 cells co-expressing CD23 assessed as inhibition of CD23 shedding after 6 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2017
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50190569BDBM50190569(CHEMBL3827027)
Affinity DataIC50: 452nMAssay Description:Inhibition of ADAM8 (unknown origin) expressed in African green monkey COS7 cells co-expressing CD23 assessed as inhibition of CD23 shedding after 6 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2017
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50421690BDBM50421690(CHEMBL5276957)
Affinity DataIC50: 567nMAssay Description:Inhibition of human recombinant ADAM8 using PepDAB13 as substrate preincubated with enzyme for 45 mins followed by substrate addition and measured fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50421690BDBM50421690(CHEMBL5276957)
Affinity DataIC50: 800nMAssay Description:Inhibition of ADAM8 (unknown origin) expressed in HEK293 cells assessed as inhibition of CD23 shedding by measuring reduction of soluble CD23 release...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50190510BDBM50190510(CHEMBL3827271)
Affinity DataIC50: 890nMAssay Description:Inhibition of ADAM8 (unknown origin) expressed in African green monkey COS7 cells co-expressing CD23 assessed as inhibition of CD23 shedding after 6 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2017
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50203527BDBM50203527(methyl (6S,7S)-7-[(hydroxyamino)carbonyl]-6-[(4-ph...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of ADAM8More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50190574BDBM50190574(CHEMBL3828603)
Affinity DataIC50: 1.25E+3nMAssay Description:Inhibition of ADAM8 (unknown origin) expressed in African green monkey COS7 cells co-expressing CD23 assessed as inhibition of CD23 shedding after 6 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2017
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50421688BDBM50421688(CHEMBL5267938)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of ADAM8 (unknown origin) expressed in HEK293 cells assessed as inhibition of CD23 shedding by measuring reduction of soluble CD23 release...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50190507BDBM50190507(CHEMBL3827625)
Affinity DataIC50: 1.65E+3nMAssay Description:Inhibition of ADAM8 (unknown origin) expressed in African green monkey COS7 cells co-expressing CD23 assessed as inhibition of CD23 shedding after 6 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2017
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50190509BDBM50190509(CHEMBL3827487)
Affinity DataIC50: 2.35E+3nMAssay Description:Inhibition of ADAM8 (unknown origin) expressed in African green monkey COS7 cells co-expressing CD23 assessed as inhibition of CD23 shedding after 6 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2017
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50190572BDBM50190572(CHEMBL3827131)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of ADAM8 (unknown origin) expressed in African green monkey COS7 cells co-expressing CD23 assessed as inhibition of CD23 shedding after 6 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2017
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50190570BDBM50190570(CHEMBL3827100)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of ADAM8 (unknown origin) expressed in African green monkey COS7 cells co-expressing CD23 assessed as inhibition of CD23 shedding after 6 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2017
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50190571BDBM50190571(CHEMBL3828319)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of ADAM8 (unknown origin) expressed in African green monkey COS7 cells co-expressing CD23 assessed as inhibition of CD23 shedding after 6 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2017
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50190573BDBM50190573(CHEMBL3828248)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of ADAM8 (unknown origin) expressed in African green monkey COS7 cells co-expressing CD23 assessed as inhibition of CD23 shedding after 6 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2017
Entry Details Article
PubMed