Compile Data Set for Download or QSAR
Report error Found 975 Enz. Inhib. hit(s) with Target = 'Dual specificity protein kinase CLK4'
TargetDual specificity protein kinase CLK4(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM15138(Biochemistry 469551 Compound 11 | 5-indazolyl pyri...)
Affinity DataKd:  0.530nMAssay Description:Binding constant for CLK4 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK4(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50589394(CHEMBL4797564)
Affinity DataKd:  0.610nMAssay Description:Binding affinity to CLK4 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetDual specificity protein kinase CLK4(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50589394(CHEMBL4797564)
Affinity DataIC50: 0.610nMAssay Description:Inhibition of human CLK4 administered orallyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetDual specificity protein kinase CLK4(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50581211(CHEMBL5093650)
Affinity DataKd:  0.800nMAssay Description:Inhibition of human partial length CLK4 (R135/K481) expressed in bacterial system by DiscoveryX Kinomescan binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK4(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50627506(CHEMBL5404544)
Affinity DataIC50: 1nMAssay Description:Inhibition of human CLK4 using MBP and [gamma33P]ATP as substrate incubated for 60 mins by radiometric 33PanQinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetDual specificity protein kinase CLK4(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM293424(US10106527, Compound 142 | US10106527, Compound 14...)
Affinity DataIC50: 1nMAssay Description:Inhibition of CLK4 (unknown origin) by Z'-LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetDual specificity protein kinase CLK4(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50627483(CHEMBL5428651)
Affinity DataIC50: 1nMAssay Description:Inhibition of human CLK4 using MBP and [gamma33P]ATP as substrate incubated for 60 mins by radiometric 33PanQinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetDual specificity protein kinase CLK4(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50627575(CHEMBL5405233)
Affinity DataIC50: 1nMAssay Description:Inhibition of human CLK4 using MBP and [gamma33P]ATP as substrate incubated for 60 mins by radiometric 33PanQinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetDual specificity protein kinase CLK4(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50627487(CHEMBL5405059)
Affinity DataIC50: 2nMAssay Description:Inhibition of human CLK4 using MBP and [gamma33P]ATP as substrate incubated for 60 mins by radiometric 33PanQinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetDual specificity protein kinase CLK4(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50627488(CHEMBL5417147)
Affinity DataIC50: 2nMAssay Description:Inhibition of human CLK4 using MBP and [gamma33P]ATP as substrate incubated for 60 mins by radiometric 33PanQinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetDual specificity protein kinase CLK4(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50627430(CHEMBL5414514)
Affinity DataIC50: 2nMAssay Description:Inhibition of human CLK4 using MBP and [gamma33P]ATP as substrate incubated for 60 mins by radiometric 33PanQinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetDual specificity protein kinase CLK4(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50627494(CHEMBL5422654)
Affinity DataIC50: 2nMAssay Description:Inhibition of human CLK4 using MBP and [gamma33P]ATP as substrate incubated for 60 mins by radiometric 33PanQinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetDual specificity protein kinase CLK4(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50627396(CHEMBL5404416)
Affinity DataIC50: 2nMAssay Description:Inhibition of human CLK4 using MBP and [gamma33P]ATP as substrate incubated for 60 mins by radiometric 33PanQinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetDual specificity protein kinase CLK4(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50627497(CHEMBL5412565)
Affinity DataIC50: 2nMAssay Description:Inhibition of human CLK4 using MBP and [gamma33P]ATP as substrate incubated for 60 mins by radiometric 33PanQinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetDual specificity protein kinase CLK4(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50627495(CHEMBL5418722)
Affinity DataIC50: 2nMAssay Description:Inhibition of human CLK4 using MBP and [gamma33P]ATP as substrate incubated for 60 mins by radiometric 33PanQinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetDual specificity protein kinase CLK4(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50627496(CHEMBL5409574)
Affinity DataIC50: 2nMAssay Description:Inhibition of human CLK4 using MBP and [gamma33P]ATP as substrate incubated for 60 mins by radiometric 33PanQinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetDual specificity protein kinase CLK4(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50631414(CHEMBL5429691)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of human CLK4 assessed as incorporation of 33Pi using [gamma-33P]-ATP measured after 60 mins by microplate scintillation counting based ra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetDual specificity protein kinase CLK4(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 2.20nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetDual specificity protein kinase CLK4(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50239782(CHEMBL4082113)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of human CLK4More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetDual specificity protein kinase CLK4(Mouse)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50239782(CHEMBL4082113)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of recombinant GST-tagged mouse CLK4 using GRSRSRSRSRSR as substrate after 30 mins in presence of [gamma-32P]-ATP by scintillation countin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2019
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK4(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50: 2.60nMAssay Description:Inhibition of recombinant human CLK4 expressed in Sf9 insect cells incubated for 60 mins in presence of ATP and [gamma33-P] ATP by radiometric scinti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetDual specificity protein kinase CLK4(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50459995(CHEMBL4225966 | US11471446, Compound DBA-10)
Affinity DataIC50: 2.70nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetDual specificity protein kinase CLK4(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50636431(CHEMBL5561973)
Affinity DataIC50: 2.90nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetDual specificity protein kinase CLK4(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50627505(CHEMBL5429404)
Affinity DataIC50: 3nMAssay Description:Inhibition of human CLK4 using MBP and [gamma33P]ATP as substrate incubated for 60 mins by radiometric 33PanQinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetDual specificity protein kinase CLK4(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50627394(CHEMBL5438293)
Affinity DataIC50: 3nMAssay Description:Inhibition of human CLK4 using MBP and [gamma33P]ATP as substrate incubated for 60 mins by radiometric 33PanQinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetDual specificity protein kinase CLK4(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50308060(CEP-701 | 16-hydroxy-16-(hydroxymethyl)-15-methyl-...)
Affinity DataKd:  3nMAssay Description:Binding affinity to CLK4More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK4(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50627397(CHEMBL5420645)
Affinity DataIC50: 3nMAssay Description:Inhibition of human CLK4 using MBP and [gamma33P]ATP as substrate incubated for 60 mins by radiometric 33PanQinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetDual specificity protein kinase CLK4(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50627478(CHEMBL5426735)
Affinity DataIC50: 3nMAssay Description:Inhibition of human CLK4 using MBP and [gamma33P]ATP as substrate incubated for 60 mins by radiometric 33PanQinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetDual specificity protein kinase CLK4(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50627475(CHEMBL5401116)
Affinity DataIC50: 3nMAssay Description:Inhibition of human CLK4 using MBP and [gamma33P]ATP as substrate incubated for 60 mins by radiometric 33PanQinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetDual specificity protein kinase CLK4(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50308060(CEP-701 | 16-hydroxy-16-(hydroxymethyl)-15-methyl-...)
Affinity DataKd:  3nMAssay Description:Binding constant for CLK4 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK4(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50627434(CHEMBL5437778)
Affinity DataIC50: 3nMAssay Description:Inhibition of human CLK4 using MBP and [gamma33P]ATP as substrate incubated for 60 mins by radiometric 33PanQinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetDual specificity protein kinase CLK4(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50627416(CHEMBL5427398)
Affinity DataIC50: 3nMAssay Description:Inhibition of human CLK4 using MBP and [gamma33P]ATP as substrate incubated for 60 mins by radiometric 33PanQinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetDual specificity protein kinase CLK4(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50627451(CHEMBL5440511)
Affinity DataIC50: 3nMAssay Description:Inhibition of human CLK4 using MBP and [gamma33P]ATP as substrate incubated for 60 mins by radiometric 33PanQinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetDual specificity protein kinase CLK4(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50627420(CHEMBL5396550)
Affinity DataIC50: 3nMAssay Description:Inhibition of human CLK4 using MBP and [gamma33P]ATP as substrate incubated for 60 mins by radiometric 33PanQinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetDual specificity protein kinase CLK4(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50639265(CHEMBL5561941)
Affinity DataIC50: 3.20nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetDual specificity protein kinase CLK4(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50627490(CHEMBL5422486)
Affinity DataIC50: 4nMAssay Description:Inhibition of human CLK4 using MBP and [gamma33P]ATP as substrate incubated for 60 mins by radiometric 33PanQinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetDual specificity protein kinase CLK4(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50627580(CHEMBL5429707)
Affinity DataIC50: 4nMAssay Description:Inhibition of human CLK4 using MBP and [gamma33P]ATP as substrate incubated for 60 mins by radiometric 33PanQinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetDual specificity protein kinase CLK4(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50627433(CHEMBL5401675)
Affinity DataIC50: 4nMAssay Description:Inhibition of human CLK4 using MBP and [gamma33P]ATP as substrate incubated for 60 mins by radiometric 33PanQinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetDual specificity protein kinase CLK4(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50627529(CHEMBL5395707)
Affinity DataIC50: 4nMAssay Description:Inhibition of human CLK4 using MBP and [gamma33P]ATP as substrate incubated for 60 mins by radiometric 33PanQinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetDual specificity protein kinase CLK4(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50627466(CHEMBL5409730)
Affinity DataIC50: 4nMAssay Description:Inhibition of human CLK4 using MBP and [gamma33P]ATP as substrate incubated for 60 mins by radiometric 33PanQinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetDual specificity protein kinase CLK4(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50627399(CHEMBL5405572)
Affinity DataIC50: 4nMAssay Description:Inhibition of human CLK4 using MBP and [gamma33P]ATP as substrate incubated for 60 mins by radiometric 33PanQinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetDual specificity protein kinase CLK4(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50627437(CHEMBL5438325)
Affinity DataIC50: 4nMAssay Description:Inhibition of human CLK4 using MBP and [gamma33P]ATP as substrate incubated for 60 mins by radiometric 33PanQinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetDual specificity protein kinase CLK4(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50627501(CHEMBL5430415)
Affinity DataIC50: 4nMAssay Description:Inhibition of human CLK4 using MBP and [gamma33P]ATP as substrate incubated for 60 mins by radiometric 33PanQinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetDual specificity protein kinase CLK4(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50627436(CHEMBL5420497)
Affinity DataIC50: 4nMAssay Description:Inhibition of human CLK4 using MBP and [gamma33P]ATP as substrate incubated for 60 mins by radiometric 33PanQinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetDual specificity protein kinase CLK4(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50627445(CHEMBL5440139)
Affinity DataIC50: 4nMAssay Description:Inhibition of human CLK4 using MBP and [gamma33P]ATP as substrate incubated for 60 mins by radiometric 33PanQinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetDual specificity protein kinase CLK4(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50435449(CHEMBL2392364)
Affinity DataIC50: 4nMAssay Description:Inhibition of CLK4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK4(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50627383(CHEMBL5423245)
Affinity DataIC50: 4nMAssay Description:Inhibition of human CLK4 using MBP and [gamma33P]ATP as substrate incubated for 60 mins by radiometric 33PanQinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetDual specificity protein kinase CLK4(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50500350(CHEMBL3746678)
Affinity DataIC50: 4nMAssay Description:Inhibition of CLK4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK4(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50627417(CHEMBL5396991)
Affinity DataIC50: 4nMAssay Description:Inhibition of human CLK4 using MBP and [gamma33P]ATP as substrate incubated for 60 mins by radiometric 33PanQinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetDual specificity protein kinase CLK4(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50627418(CHEMBL5411888)
Affinity DataIC50: 4nMAssay Description:Inhibition of human CLK4 using MBP and [gamma33P]ATP as substrate incubated for 60 mins by radiometric 33PanQinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
Displayed 1 to 50 (of 975 total ) | Next | Last >>
Jump to: