Compile Data Set for Download or QSAR
Report error Found 948 Enz. Inhib. hit(s) with Target = 'E3 ubiquitin-protein ligase XIAP [241-356]'
TargetE3 ubiquitin-protein ligase XIAP [241-356](Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 249163BDBM249163(US9453048, 4)
Affinity DataIC50: 0.0600nMT: 2°CAssay Description:Assays were performed in black, flat-bottom, 384-well plates. The final assay volume was 50 μL prepared from additions of N-His-Tb-BIR3(241-356,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2017
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [241-356](Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 249161BDBM249161(US9453048, 2)
Affinity DataIC50: 0.0600nMT: 2°CAssay Description:Assays were performed in black, flat-bottom, 384-well plates. The final assay volume was 50 μL prepared from additions of N-His-Tb-BIR3(241-356,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2017
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [241-356](Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 249169BDBM249169(US9453048, 11 | US9453048, 12)
Affinity DataIC50: 0.0600nMT: 2°CAssay Description:Assays were performed in black, flat-bottom, 384-well plates. The final assay volume was 50 μL prepared from additions of N-His-Tb-BIR3(241-356,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2017
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [241-356](Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 249167BDBM249167(US9453048, 9)
Affinity DataIC50: 0.0600nMT: 2°CAssay Description:Assays were performed in black, flat-bottom, 384-well plates. The final assay volume was 50 μL prepared from additions of N-His-Tb-BIR3(241-356,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2017
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [241-356](Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 249174BDBM249174(US9453048, 16)
Affinity DataIC50: 0.0700nMT: 2°CAssay Description:Assays were performed in black, flat-bottom, 384-well plates. The final assay volume was 50 μL prepared from additions of N-His-Tb-BIR3(241-356,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2017
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [241-356](Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 249162BDBM249162(US9453048, 3)
Affinity DataIC50: 0.0800nMT: 2°CAssay Description:Assays were performed in black, flat-bottom, 384-well plates. The final assay volume was 50 μL prepared from additions of N-His-Tb-BIR3(241-356,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2017
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [241-356](Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 249172BDBM249172(US9453048, 14)
Affinity DataIC50: 0.0800nMT: 2°CAssay Description:Assays were performed in black, flat-bottom, 384-well plates. The final assay volume was 50 μL prepared from additions of N-His-Tb-BIR3(241-356,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2017
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [241-356](Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 249168BDBM249168(US9453048, 10)
Affinity DataIC50: 0.130nMT: 2°CAssay Description:Assays were performed in black, flat-bottom, 384-well plates. The final assay volume was 50 μL prepared from additions of N-His-Tb-BIR3(241-356,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2017
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [241-356](Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 249160BDBM249160(US9453048, 1)
Affinity DataIC50: 0.140nMT: 2°CAssay Description:Assays were performed in black, flat-bottom, 384-well plates. The final assay volume was 50 μL prepared from additions of N-His-Tb-BIR3(241-356,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2017
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [241-356](Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 249165BDBM249165(US9453048, 6)
Affinity DataIC50: 0.140nMT: 2°CAssay Description:Assays were performed in black, flat-bottom, 384-well plates. The final assay volume was 50 μL prepared from additions of N-His-Tb-BIR3(241-356,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2017
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [241-356](Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 249166BDBM249166(US9453048, 7)
Affinity DataIC50: 0.140nMT: 2°CAssay Description:Assays were performed in black, flat-bottom, 384-well plates. The final assay volume was 50 μL prepared from additions of N-His-Tb-BIR3(241-356,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2017
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [241-356](Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 249171BDBM249171(US9453048, 13 | US9453048, 15)
Affinity DataIC50: 0.150nMT: 2°CAssay Description:Assays were performed in black, flat-bottom, 384-well plates. The final assay volume was 50 μL prepared from additions of N-His-Tb-BIR3(241-356,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2017
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [241-356](Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 249164BDBM249164(US9453048, 5)
Affinity DataIC50: 0.160nMT: 2°CAssay Description:Assays were performed in black, flat-bottom, 384-well plates. The final assay volume was 50 μL prepared from additions of N-His-Tb-BIR3(241-356,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2017
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [241-356](Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 249178BDBM249178(US9453048, 20)
Affinity DataIC50: 0.180nMT: 2°CAssay Description:Assays were performed in black, flat-bottom, 384-well plates. The final assay volume was 50 μL prepared from additions of N-His-Tb-BIR3(241-356,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2017
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [241-356](Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 249177BDBM249177(US9453048, 19)
Affinity DataIC50: 0.210nMT: 2°CAssay Description:Assays were performed in black, flat-bottom, 384-well plates. The final assay volume was 50 μL prepared from additions of N-His-Tb-BIR3(241-356,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2017
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [241-356](Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 249176BDBM249176(US9453048, 18)
Affinity DataIC50: 0.220nMT: 2°CAssay Description:Assays were performed in black, flat-bottom, 384-well plates. The final assay volume was 50 μL prepared from additions of N-His-Tb-BIR3(241-356,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2017
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [241-356](Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 249171BDBM249171(US9453048, 13 | US9453048, 15)
Affinity DataIC50: 0.230nMT: 2°CAssay Description:Assays were performed in black, flat-bottom, 384-well plates. The final assay volume was 50 μL prepared from additions of N-His-Tb-BIR3(241-356,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2017
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [241-356](Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 249169BDBM249169(US9453048, 11 | US9453048, 12)
Affinity DataIC50: 0.25nMT: 2°CAssay Description:Assays were performed in black, flat-bottom, 384-well plates. The final assay volume was 50 μL prepared from additions of N-His-Tb-BIR3(241-356,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2017
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [241-356](Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 249175BDBM249175(US9453048, 17)
Affinity DataIC50: 0.270nMT: 2°CAssay Description:Assays were performed in black, flat-bottom, 384-well plates. The final assay volume was 50 μL prepared from additions of N-His-Tb-BIR3(241-356,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2017
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [241-356](Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 205417BDBM205417(US9249151, 63)
Affinity DataIC50: 1nMT: 2°CAssay Description:R3 domains of human XIAP (covering amino acids 241 to 356; XIAP BIR3) and cIAPl (covering amino acids 256 to 363; cIAPl BIR3) were expressed and puri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [241-356](Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 205375BDBM205375(US9249151, 21 | US9249151, 60)
Affinity DataIC50: 1nMT: 2°CAssay Description:R3 domains of human XIAP (covering amino acids 241 to 356; XIAP BIR3) and cIAPl (covering amino acids 256 to 363; cIAPl BIR3) were expressed and puri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [241-356](Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 412171BDBM412171(US10398702, Example 10 | (3S)-2-[(2S)-3,3-dimethyl...)
Affinity DataIC50: 2nMAssay Description:For the Bir3 assay, 13.3 nanomolar BIR3 domain, corresponding to amino acids 241-356 of XIAP, was mixed with 25.2 nM of the peptide AVPIAQKSEK-(ε...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [241-356](Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 412166BDBM412166(US10398702, Example 5 | (3S)-2-((S)-3,3-dimethyl-2...)
Affinity DataIC50: 3nMAssay Description:For the Bir3 assay, 13.3 nanomolar BIR3 domain, corresponding to amino acids 241-356 of XIAP, was mixed with 25.2 nM of the peptide AVPIAQKSEK-(ε...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [241-356](Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 412164BDBM412164(US10398702, Example 3 | tert-Butyl (2R,5S)-4-[2-[3...)
Affinity DataIC50: 3nMAssay Description:For the Bir3 assay, 13.3 nanomolar BIR3 domain, corresponding to amino acids 241-356 of XIAP, was mixed with 25.2 nM of the peptide AVPIAQKSEK-(ε...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [241-356](Mouse)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 228611BDBM228611(US9345740, 8)
Affinity DataIC50: 3nMT: 2°CAssay Description:Assays were performed in black, flat-bottom, 384-well plates. The final assay volume was 50 μL prepared from additions of His-BIR3 (241-356, XIAP)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2017
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [241-356](Artificial Sequence)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 228603BDBM228603(US9340573, 14)
Affinity DataIC50: 3.95nMpH: 7.5 T: 2°CAssay Description:The peptide AVPIAQKSEK-(ε-biotin)-OH 1:2 TFA ("Peptide A") was identified as a substrate for the TR-FRET assay by screening the 6× Hist...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2017
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [241-356](Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 412169BDBM412169(US10398702, Example 8 | (3S)-N-[2-[[(3S)-3-[(2,6- ...)
Affinity DataIC50: 4nMAssay Description:For the Bir3 assay, 13.3 nanomolar BIR3 domain, corresponding to amino acids 241-356 of XIAP, was mixed with 25.2 nM of the peptide AVPIAQKSEK-(ε...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [241-356](Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 13174BDBM13174(H-N-Me-Ala-Tle-(4S)-4-phenoxy-Pro-(R)-tetrahydrona...)
Affinity DataKd:  5nMpH: 7.4 T: 2°CAssay Description:A fluorescence polarization anisotropy (FPA) competition assay was used to determine the affinities of compounds to BIR3 protein. Fluorescence polari...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2007
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase XIAP [241-356](Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 412181BDBM412181(US10398702, Example 20 | (S)-N-(2-(((S)-3-((2,6- d...)
Affinity DataIC50: 5nMAssay Description:For the Bir3 assay, 13.3 nanomolar BIR3 domain, corresponding to amino acids 241-356 of XIAP, was mixed with 25.2 nM of the peptide AVPIAQKSEK-(ε...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [241-356](Artificial Sequence)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 228602BDBM228602(US9340573, 13)
Affinity DataIC50: 5.34nMpH: 7.5 T: 2°CAssay Description:The peptide AVPIAQKSEK-(ε-biotin)-OH 1:2 TFA ("Peptide A") was identified as a substrate for the TR-FRET assay by screening the 6× Hist...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2017
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [241-356](Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 412182BDBM412182(US10398702, Example 21 | tert-Butyl (2R,5S)-4-[2-[...)
Affinity DataIC50: 6nMAssay Description:For the Bir3 assay, 13.3 nanomolar BIR3 domain, corresponding to amino acids 241-356 of XIAP, was mixed with 25.2 nM of the peptide AVPIAQKSEK-(ε...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [241-356](Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 13176BDBM13176(H-N-Me-Ala-Chg-(4S)-4-phenoxy-Pro-(R)-tetrahydrona...)
Affinity DataKd:  6nMpH: 7.4 T: 2°CAssay Description:A fluorescence polarization anisotropy (FPA) competition assay was used to determine the affinities of compounds to BIR3 protein. Fluorescence polari...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2007
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase XIAP [241-356](Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 412178BDBM412178(US10398702, Example 17 | tert-Butyl N-[(1 S)-2-[[(...)
Affinity DataIC50: 7nMAssay Description:For the Bir3 assay, 13.3 nanomolar BIR3 domain, corresponding to amino acids 241-356 of XIAP, was mixed with 25.2 nM of the peptide AVPIAQKSEK-(ε...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [241-356](Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 240880BDBM240880(US9409888, 2)
Affinity DataIC50: 7.33nMpH: 7.5 T: 2°CAssay Description:Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [241-356](Mouse)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 228613BDBM228613(US9345740, 10)
Affinity DataIC50: 8nMT: 2°CAssay Description:Assays were performed in black, flat-bottom, 384-well plates. The final assay volume was 50 μL prepared from additions of His-BIR3 (241-356, XIAP)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2017
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [241-356](Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 412180BDBM412180(US10398702, Example 19 | tert-Butyl (2R,5S)-4-[2-[...)
Affinity DataIC50: 8nMAssay Description:For the Bir3 assay, 13.3 nanomolar BIR3 domain, corresponding to amino acids 241-356 of XIAP, was mixed with 25.2 nM of the peptide AVPIAQKSEK-(ε...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [241-356](Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 412167BDBM412167(US10398702, Example 6 | (3S)-2-((S)-3,3-dimethyl- ...)
Affinity DataIC50: 8nMAssay Description:For the Bir3 assay, 13.3 nanomolar BIR3 domain, corresponding to amino acids 241-356 of XIAP, was mixed with 25.2 nM of the peptide AVPIAQKSEK-(ε...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [241-356](Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 412176BDBM412176(US10398702, Example 15 | tert-Butyl (2R,5S)-4-[2-[...)
Affinity DataIC50: 9nMAssay Description:For the Bir3 assay, 13.3 nanomolar BIR3 domain, corresponding to amino acids 241-356 of XIAP, was mixed with 25.2 nM of the peptide AVPIAQKSEK-(ε...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [241-356](Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 412183BDBM412183(US10398702, Example 22 | tert-Butyl (2R,5S)-4-[2-[...)
Affinity DataIC50: 9nMAssay Description:For the Bir3 assay, 13.3 nanomolar BIR3 domain, corresponding to amino acids 241-356 of XIAP, was mixed with 25.2 nM of the peptide AVPIAQKSEK-(ε...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [241-356](Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 213387BDBM213387(US9278978, 22)
Affinity DataIC50: 10nMT: 2°CAssay Description:BIR3 domains (10 nM) were incubated with SMAC peptide (10 nM) in assay buffer (50 mM Tris, 120 mM NaCl, 0.1% BSA, 1 mM DTT, 0.05% TritonX100) for one...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2017
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [241-356](Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 422082BDBM422082(US10508103, Embodiment 39)
Affinity DataIC50: 10nMAssay Description:1) Affinity of compounds listed in table to cIAP1-BIR3, Ciap2-BIR3, XIAP-BIR3 was tested referring to Nikolovska-Colesks, Z. et.Al. (Analytical Bioch...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2020
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [241-356](Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 422075BDBM422075(US10508103, Embodiment 28)
Affinity DataIC50: 10nMAssay Description:1) Affinity of compounds listed in table to cIAP1-BIR3, Ciap2-BIR3, XIAP-BIR3 was tested referring to Nikolovska-Colesks, Z. et.Al. (Analytical Bioch...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2020
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [241-356](Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 422086BDBM422086(US10508103, Embodiment 44)
Affinity DataIC50: 10nMAssay Description:1) Affinity of compounds listed in table to cIAP1-BIR3, Ciap2-BIR3, XIAP-BIR3 was tested referring to Nikolovska-Colesks, Z. et.Al. (Analytical Bioch...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2020
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [241-356](Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 422081BDBM422081(US10508103, Embodiment 38)
Affinity DataIC50: 10nMAssay Description:1) Affinity of compounds listed in table to cIAP1-BIR3, Ciap2-BIR3, XIAP-BIR3 was tested referring to Nikolovska-Colesks, Z. et.Al. (Analytical Bioch...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2020
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [241-356](Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 205365BDBM205365(US9249151, 11)
Affinity DataIC50: 10nMT: 2°CAssay Description:R3 domains of human XIAP (covering amino acids 241 to 356; XIAP BIR3) and cIAPl (covering amino acids 256 to 363; cIAPl BIR3) were expressed and puri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [241-356](Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 205413BDBM205413(US9249151, 59)
Affinity DataIC50: 10nMT: 2°CAssay Description:R3 domains of human XIAP (covering amino acids 241 to 356; XIAP BIR3) and cIAPl (covering amino acids 256 to 363; cIAPl BIR3) were expressed and puri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [241-356](Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 422074BDBM422074(US10508103, Embodiment 27)
Affinity DataIC50: 10nMAssay Description:1) Affinity of compounds listed in table to cIAP1-BIR3, Ciap2-BIR3, XIAP-BIR3 was tested referring to Nikolovska-Colesks, Z. et.Al. (Analytical Bioch...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2020
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [241-356](Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 422064BDBM422064(US10508103, Embodiment 17)
Affinity DataIC50: 10nMAssay Description:1) Affinity of compounds listed in table to cIAP1-BIR3, Ciap2-BIR3, XIAP-BIR3 was tested referring to Nikolovska-Colesks, Z. et.Al. (Analytical Bioch...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2020
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [241-356](Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 422073BDBM422073(US10508103, Embodiment 26)
Affinity DataIC50: 10nMAssay Description:1) Affinity of compounds listed in table to cIAP1-BIR3, Ciap2-BIR3, XIAP-BIR3 was tested referring to Nikolovska-Colesks, Z. et.Al. (Analytical Bioch...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2020
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [241-356](Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 422084BDBM422084(US10508103, Embodiment 42)
Affinity DataIC50: 10nMAssay Description:1) Affinity of compounds listed in table to cIAP1-BIR3, Ciap2-BIR3, XIAP-BIR3 was tested referring to Nikolovska-Colesks, Z. et.Al. (Analytical Bioch...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2020
Entry Details
US Patent

Displayed 1 to 50 (of 948 total ) | Next | Last >>
Jump to: