Compile Data Set for Download or QSAR
Report error Found 45 Enz. Inhib. hit(s) with Target = 'E3 ubiquitin-protein ligase XIAP [163-230]/[26-93]'
TargetE3 ubiquitin-protein ligase XIAP [163-230]/[26-93](Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 391830BDBM391830(US10300074, Compd 25 | US11111270, Compound 25)
Affinity DataKi: <2.50E+4nMAssay Description:5000 PPC-1 cells were plated and grown overnight. Compounds were plated and 4 hrs later, TRAIL was added to half of the plate while RPMI was added to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2022
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [163-230]/[26-93](Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 391831BDBM391831(US10300074, Compd 26 | US11111270, Compound 26)
Affinity DataKi: <2.50E+4nMAssay Description:5000 PPC-1 cells were plated and grown overnight. Compounds were plated and 4 hrs later, TRAIL was added to half of the plate while RPMI was added to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2022
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [163-230]/[26-93](Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 518375BDBM518375(US11111270, Compound 40)
Affinity DataKi: <2.50E+4nMAssay Description:5000 PPC-1 cells were plated and grown overnight. Compounds were plated and 4 hrs later, TRAIL was added to half of the plate while RPMI was added to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2022
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [163-230]/[26-93](Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 518266BDBM518266(US11111270, Compound 13)
Affinity DataKi: <2.50E+4nMAssay Description:5000 PPC-1 cells were plated and grown overnight. Compounds were plated and 4 hrs later, TRAIL was added to half of the plate while RPMI was added to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2022
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [163-230]/[26-93](Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 518376BDBM518376(US11111270, Compound 41)
Affinity DataKi: <2.50E+4nMAssay Description:5000 PPC-1 cells were plated and grown overnight. Compounds were plated and 4 hrs later, TRAIL was added to half of the plate while RPMI was added to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2022
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [163-230]/[26-93](Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 518377BDBM518377(US11111270, Compound 42)
Affinity DataKi: <2.50E+4nMAssay Description:5000 PPC-1 cells were plated and grown overnight. Compounds were plated and 4 hrs later, TRAIL was added to half of the plate while RPMI was added to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2022
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [163-230]/[26-93](Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 518378BDBM518378(US11111270, Compound 43)
Affinity DataKi: <2.50E+4nMAssay Description:5000 PPC-1 cells were plated and grown overnight. Compounds were plated and 4 hrs later, TRAIL was added to half of the plate while RPMI was added to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2022
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [163-230]/[26-93](Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 391835BDBM391835(US10300074, Compd 31 | US10300074, Compd 30 | US11...)
Affinity DataKi: <2.50E+4nMAssay Description:5000 PPC-1 cells were plated and grown overnight. Compounds were plated and 4 hrs later, TRAIL was added to half of the plate while RPMI was added to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2022
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [163-230]/[26-93](Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 518379BDBM518379(US11111270, Compound 44)
Affinity DataKi: <2.50E+4nMAssay Description:5000 PPC-1 cells were plated and grown overnight. Compounds were plated and 4 hrs later, TRAIL was added to half of the plate while RPMI was added to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2022
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [163-230]/[26-93](Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 518275BDBM518275(US11111270, Compound 17)
Affinity DataKi: <2.50E+4nMAssay Description:5000 PPC-1 cells were plated and grown overnight. Compounds were plated and 4 hrs later, TRAIL was added to half of the plate while RPMI was added to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2022
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [163-230]/[26-93](Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 518381BDBM518381(US11111270, Compound 45)
Affinity DataKi: <2.50E+4nMAssay Description:5000 PPC-1 cells were plated and grown overnight. Compounds were plated and 4 hrs later, TRAIL was added to half of the plate while RPMI was added to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2022
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [163-230]/[26-93](Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 518384BDBM518384(US11111270, Compound 47)
Affinity DataKi: <2.50E+4nMAssay Description:5000 PPC-1 cells were plated and grown overnight. Compounds were plated and 4 hrs later, TRAIL was added to half of the plate while RPMI was added to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2022
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [163-230]/[26-93](Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 391806BDBM391806(US10300074, Product 17c | US11111270, Compound 35)
Affinity DataKi: <2.50E+4nMAssay Description:5000 PPC-1 cells were plated and grown overnight. Compounds were plated and 4 hrs later, TRAIL was added to half of the plate while RPMI was added to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2022
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [163-230]/[26-93](Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 518274BDBM518274(US11111270, Compound 16)
Affinity DataKi:  3.75E+4nMAssay Description:5000 PPC-1 cells were plated and grown overnight. Compounds were plated and 4 hrs later, TRAIL was added to half of the plate while RPMI was added to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2022
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [163-230]/[26-93](Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 391814BDBM391814(US10300074, Compd 10 | US11111270, Compound 10)
Affinity DataKi: >5.00E+4nMAssay Description:5000 PPC-1 cells were plated and grown overnight. Compounds were plated and 4 hrs later, TRAIL was added to half of the plate while RPMI was added to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2022
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [163-230]/[26-93](Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 391842BDBM391842(US10300074, Compd 37 | US11111270, Compound 37)
Affinity DataKi: >5.00E+4nMAssay Description:5000 PPC-1 cells were plated and grown overnight. Compounds were plated and 4 hrs later, TRAIL was added to half of the plate while RPMI was added to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2022
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [163-230]/[26-93](Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 391815BDBM391815(US10300074, Compd 11 | US11111270, Compound 11)
Affinity DataKi: >5.00E+4nMAssay Description:5000 PPC-1 cells were plated and grown overnight. Compounds were plated and 4 hrs later, TRAIL was added to half of the plate while RPMI was added to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2022
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [163-230]/[26-93](Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 391843BDBM391843(US10300074, Compd 38 | US11111270, Compound 38)
Affinity DataKi: >5.00E+4nMAssay Description:5000 PPC-1 cells were plated and grown overnight. Compounds were plated and 4 hrs later, TRAIL was added to half of the plate while RPMI was added to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2022
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [163-230]/[26-93](Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 391816BDBM391816(US10300074, Compd 12 | US11111270, Compound 12)
Affinity DataKi: >5.00E+4nMAssay Description:5000 PPC-1 cells were plated and grown overnight. Compounds were plated and 4 hrs later, TRAIL was added to half of the plate while RPMI was added to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2022
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [163-230]/[26-93](Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 391844BDBM391844(US10300074, Compd 39 | US11111270, Compound 39)
Affinity DataKi: >5.00E+4nMAssay Description:5000 PPC-1 cells were plated and grown overnight. Compounds were plated and 4 hrs later, TRAIL was added to half of the plate while RPMI was added to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2022
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [163-230]/[26-93](Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 391819BDBM391819(US10300074, Compd 14 | US11111270, Compound 14)
Affinity DataKi: >5.00E+4nMAssay Description:5000 PPC-1 cells were plated and grown overnight. Compounds were plated and 4 hrs later, TRAIL was added to half of the plate while RPMI was added to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2022
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [163-230]/[26-93](Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 391820BDBM391820(US10300074, Compd 15 | US11111270, Compound 15)
Affinity DataKi: >5.00E+4nMAssay Description:5000 PPC-1 cells were plated and grown overnight. Compounds were plated and 4 hrs later, TRAIL was added to half of the plate while RPMI was added to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2022
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [163-230]/[26-93](Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 391807BDBM391807(US10300074, Compd 4 | US10300074, Compd 7 | US1030...)
Affinity DataKi: >5.00E+4nMAssay Description:5000 PPC-1 cells were plated and grown overnight. Compounds were plated and 4 hrs later, TRAIL was added to half of the plate while RPMI was added to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2022
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [163-230]/[26-93](Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 391837BDBM391837(US10300074, Compd 32 | US11111270, Compound 32)
Affinity DataKi: >5.00E+4nMAssay Description:5000 PPC-1 cells were plated and grown overnight. Compounds were plated and 4 hrs later, TRAIL was added to half of the plate while RPMI was added to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2022
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [163-230]/[26-93](Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 518256BDBM518256(US11111270, Compound 4)
Affinity DataKi: >5.00E+4nMAssay Description:5000 PPC-1 cells were plated and grown overnight. Compounds were plated and 4 hrs later, TRAIL was added to half of the plate while RPMI was added to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2022
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [163-230]/[26-93](Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 391838BDBM391838(US10300074, Compd 33 | US11111270, Compound 33)
Affinity DataKi: >5.00E+4nMAssay Description:5000 PPC-1 cells were plated and grown overnight. Compounds were plated and 4 hrs later, TRAIL was added to half of the plate while RPMI was added to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2022
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [163-230]/[26-93](Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 391809BDBM391809(US10300074, Compd 6 | US10300074, Compd 5 | US1111...)
Affinity DataKi: >5.00E+4nMAssay Description:5000 PPC-1 cells were plated and grown overnight. Compounds were plated and 4 hrs later, TRAIL was added to half of the plate while RPMI was added to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2022
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [163-230]/[26-93](Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 391809BDBM391809(US10300074, Compd 6 | US10300074, Compd 5 | US1111...)
Affinity DataKi: >5.00E+4nMAssay Description:5000 PPC-1 cells were plated and grown overnight. Compounds were plated and 4 hrs later, TRAIL was added to half of the plate while RPMI was added to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2022
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [163-230]/[26-93](Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 391839BDBM391839(US10300074, Compd 34 | US11111270, Compound 34)
Affinity DataKi: >5.00E+4nMAssay Description:5000 PPC-1 cells were plated and grown overnight. Compounds were plated and 4 hrs later, TRAIL was added to half of the plate while RPMI was added to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2022
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [163-230]/[26-93](Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 391807BDBM391807(US10300074, Compd 4 | US10300074, Compd 7 | US1030...)
Affinity DataKi: >5.00E+4nMAssay Description:5000 PPC-1 cells were plated and grown overnight. Compounds were plated and 4 hrs later, TRAIL was added to half of the plate while RPMI was added to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2022
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [163-230]/[26-93](Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 391812BDBM391812(US10300074, Compd 8 | US11111270, Compound 8)
Affinity DataKi: >5.00E+4nMAssay Description:5000 PPC-1 cells were plated and grown overnight. Compounds were plated and 4 hrs later, TRAIL was added to half of the plate while RPMI was added to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2022
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [163-230]/[26-93](Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 391813BDBM391813(US10300074, Compd 9 | US11111270, Compound 9)
Affinity DataKi: >5.00E+4nMAssay Description:5000 PPC-1 cells were plated and grown overnight. Compounds were plated and 4 hrs later, TRAIL was added to half of the plate while RPMI was added to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2022
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [163-230]/[26-93](Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 391841BDBM391841(US10300074, Compd 36 | US11111270, Compound 36)
Affinity DataKi: >5.00E+4nMAssay Description:5000 PPC-1 cells were plated and grown overnight. Compounds were plated and 4 hrs later, TRAIL was added to half of the plate while RPMI was added to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2022
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [163-230]/[26-93](Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 391804BDBM391804(US10300074, Product 17a | US11111270, Compound 27)
Affinity DataKi: >5.00E+4nMAssay Description:5000 PPC-1 cells were plated and grown overnight. Compounds were plated and 4 hrs later, TRAIL was added to half of the plate while RPMI was added to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2022
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [163-230]/[26-93](Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 518307BDBM518307(US11111270, Compound 29 | US11111270, Compound 28)
Affinity DataKi: >5.00E+4nMAssay Description:5000 PPC-1 cells were plated and grown overnight. Compounds were plated and 4 hrs later, TRAIL was added to half of the plate while RPMI was added to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2022
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [163-230]/[26-93](Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 518307BDBM518307(US11111270, Compound 29 | US11111270, Compound 28)
Affinity DataKi: >5.00E+4nMAssay Description:5000 PPC-1 cells were plated and grown overnight. Compounds were plated and 4 hrs later, TRAIL was added to half of the plate while RPMI was added to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2022
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [163-230]/[26-93](Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 391835BDBM391835(US10300074, Compd 31 | US10300074, Compd 30 | US11...)
Affinity DataKi: >5.00E+4nMAssay Description:5000 PPC-1 cells were plated and grown overnight. Compounds were plated and 4 hrs later, TRAIL was added to half of the plate while RPMI was added to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2022
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [163-230]/[26-93](Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 518278BDBM518278(US11111270, Compound 19 | US11111270, Compound 18)
Affinity DataKi: >5.00E+4nMAssay Description:5000 PPC-1 cells were plated and grown overnight. Compounds were plated and 4 hrs later, TRAIL was added to half of the plate while RPMI was added to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2022
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [163-230]/[26-93](Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 518278BDBM518278(US11111270, Compound 19 | US11111270, Compound 18)
Affinity DataKi: >5.00E+4nMAssay Description:5000 PPC-1 cells were plated and grown overnight. Compounds were plated and 4 hrs later, TRAIL was added to half of the plate while RPMI was added to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2022
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [163-230]/[26-93](Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 391851BDBM391851(US10300074, Compd 46 | US11111270, Compound 46)
Affinity DataKi: >5.00E+4nMAssay Description:5000 PPC-1 cells were plated and grown overnight. Compounds were plated and 4 hrs later, TRAIL was added to half of the plate while RPMI was added to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2022
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [163-230]/[26-93](Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 518282BDBM518282(US11111270, Compound 21 | US11111270, Compound 20)
Affinity DataKi: >5.00E+4nMAssay Description:5000 PPC-1 cells were plated and grown overnight. Compounds were plated and 4 hrs later, TRAIL was added to half of the plate while RPMI was added to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2022
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [163-230]/[26-93](Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 518282BDBM518282(US11111270, Compound 21 | US11111270, Compound 20)
Affinity DataKi: >5.00E+4nMAssay Description:5000 PPC-1 cells were plated and grown overnight. Compounds were plated and 4 hrs later, TRAIL was added to half of the plate while RPMI was added to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2022
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [163-230]/[26-93](Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 518284BDBM518284(US11111270, Compound 22)
Affinity DataKi: >5.00E+4nMAssay Description:5000 PPC-1 cells were plated and grown overnight. Compounds were plated and 4 hrs later, TRAIL was added to half of the plate while RPMI was added to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2022
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [163-230]/[26-93](Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 518285BDBM518285(US11111270, Compound 23)
Affinity DataKi: >5.00E+4nMAssay Description:5000 PPC-1 cells were plated and grown overnight. Compounds were plated and 4 hrs later, TRAIL was added to half of the plate while RPMI was added to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2022
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [163-230]/[26-93](Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 518286BDBM518286(US11111270, Compound 24)
Affinity DataKi: >5.00E+4nMAssay Description:5000 PPC-1 cells were plated and grown overnight. Compounds were plated and 4 hrs later, TRAIL was added to half of the plate while RPMI was added to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2022
Entry Details
US Patent