Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor [1-745,751-1210,T790M]'
TargetEpidermal growth factor receptor [1-745,751-1210,T790M](Human)
Xuanzhu Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 391743BDBM391743(US10300058, Compound 28 | N-(3-((2-((2-methoxy-4-(...)
Affinity DataIC50: 0.800nMAssay Description:Test compounds: a part of compounds of the invention, the chemical names and preparation methods of which can be found in their preparation examples....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-745,751-1210,T790M](Human)
Xuanzhu Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 679658BDBM679658(US20240182487, Compound 1)
Affinity DataIC50: 2.10nMAssay Description:Biochemical Assays for Inhibition of Wild-Type and Mutant EGFRs.The inhibitory activities against EGFR WT, EGFR Δ752-759 mutant, EGFR Δ746-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2024
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-745,751-1210,T790M](Human)
Xuanzhu Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 679664BDBM679664(US20240182487, Compound 63)
Affinity DataIC50: 2.80nMAssay Description:Biochemical Assays for Inhibition of Wild-Type and Mutant EGFRs.The inhibitory activities against EGFR WT, EGFR Δ752-759 mutant, EGFR Δ746-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2024
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-745,751-1210,T790M](Human)
Xuanzhu Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 391742BDBM391742(US10300058, Compound 27 | N-(3-((2-((2-methoxy-4-(...)
Affinity DataIC50: 3.60nMAssay Description:Test compounds: a part of compounds of the invention, the chemical names and preparation methods of which can be found in their preparation examples....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-745,751-1210,T790M](Human)
Xuanzhu Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 679663BDBM679663(US20240182487, Compound 62)
Affinity DataIC50: 4.10nMAssay Description:Biochemical Assays for Inhibition of Wild-Type and Mutant EGFRs.The inhibitory activities against EGFR WT, EGFR Δ752-759 mutant, EGFR Δ746-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2024
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-745,751-1210,T790M](Human)
Xuanzhu Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 679660BDBM679660(US20240182487, Compound 3)
Affinity DataIC50: 13.2nMAssay Description:Biochemical Assays for Inhibition of Wild-Type and Mutant EGFRs.The inhibitory activities against EGFR WT, EGFR Δ752-759 mutant, EGFR Δ746-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2024
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-745,751-1210,T790M](Human)
Xuanzhu Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 679659BDBM679659(US20240182487, Compound 2)
Affinity DataIC50: 22.9nMAssay Description:Biochemical Assays for Inhibition of Wild-Type and Mutant EGFRs.The inhibitory activities against EGFR WT, EGFR Δ752-759 mutant, EGFR Δ746-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2024
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-745,751-1210,T790M](Human)
Xuanzhu Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 679666BDBM679666(US20240182487, Compound 65)
Affinity DataIC50: 35.9nMAssay Description:Biochemical Assays for Inhibition of Wild-Type and Mutant EGFRs.The inhibitory activities against EGFR WT, EGFR Δ752-759 mutant, EGFR Δ746-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2024
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-745,751-1210,T790M](Human)
Xuanzhu Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 679661BDBM679661(US20240182487, Compound 16)
Affinity DataIC50: 38.4nMAssay Description:Biochemical Assays for Inhibition of Wild-Type and Mutant EGFRs.The inhibitory activities against EGFR WT, EGFR Δ752-759 mutant, EGFR Δ746-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2024
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-745,751-1210,T790M](Human)
Xuanzhu Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 679698BDBM679698(US20240182487, Compound 99)
Affinity DataIC50: 8.53E+3nMAssay Description:Biochemical Assays for Inhibition of Wild-Type and Mutant EGFRs.The inhibitory activities against EGFR WT, EGFR Δ752-759 mutant, EGFR Δ746-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2024
Entry Details
US Patent