Compile Data Set for Download or QSAR
Report error Found 246 Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor [1-745,751-1210]'
TargetEpidermal growth factor receptor [1-745,751-1210](Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 504403BDBM504403(US11040984, Compound 3)
Affinity DataIC50: 0.0200nMAssay Description:Buffer formulation: a buffer consisted of 50 mM HEPES (pH 7.5), 0.01% BSA, 5 mM MgCl2, 0.1 mM Orthovanadate. After the buffer was formulated, an enzy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2021
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-745,751-1210](Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 504412BDBM504412(US11040984, Compound 18)
Affinity DataIC50: 0.0500nMAssay Description:Buffer formulation: a buffer consisted of 50 mM HEPES (pH 7.5), 0.01% BSA, 5 mM MgCl2, 0.1 mM Orthovanadate. After the buffer was formulated, an enzy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2021
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-745,751-1210](Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 504411BDBM504411(US11040984, Compound 13)
Affinity DataIC50: 0.0520nMAssay Description:Buffer formulation: a buffer consisted of 50 mM HEPES (pH 7.5), 0.01% BSA, 5 mM MgCl2, 0.1 mM Orthovanadate. After the buffer was formulated, an enzy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2021
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-745,751-1210](Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 504415BDBM504415(US11040984, Compound 30)
Affinity DataIC50: 0.0520nMAssay Description:Buffer formulation: a buffer consisted of 50 mM HEPES (pH 7.5), 0.01% BSA, 5 mM MgCl2, 0.1 mM Orthovanadate. After the buffer was formulated, an enzy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2021
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-745,751-1210](Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 504414BDBM504414(US11040984, Compound 25)
Affinity DataIC50: 0.0690nMAssay Description:Buffer formulation: a buffer consisted of 50 mM HEPES (pH 7.5), 0.01% BSA, 5 mM MgCl2, 0.1 mM Orthovanadate. After the buffer was formulated, an enzy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2021
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-745,751-1210](Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 504408BDBM504408(US11040984, Compound 6)
Affinity DataIC50: 0.0700nMAssay Description:Buffer formulation: a buffer consisted of 50 mM HEPES (pH 7.5), 0.01% BSA, 5 mM MgCl2, 0.1 mM Orthovanadate. After the buffer was formulated, an enzy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2021
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-745,751-1210](Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 790100BDBM790100(2-{(10S,17E)-12-ethyl-8,10-dimethyl-16- [(propan-2...)
Affinity DataIC50: 0.0800nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [1-745,751-1210](Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 504410BDBM504410(US11040984, Compound 12)
Affinity DataIC50: 0.0850nMAssay Description:Buffer formulation: a buffer consisted of 50 mM HEPES (pH 7.5), 0.01% BSA, 5 mM MgCl2, 0.1 mM Orthovanadate. After the buffer was formulated, an enzy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2021
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-745,751-1210](Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 790077BDBM790077({[(10S,17E)-14-(2-hydroxyethyl)- 8,10,12-trimethyl...)
Affinity DataIC50: 0.110nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [1-745,751-1210](Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 790026BDBM790026(2-[(10S,17E)-12-ethyl-8,10,16-trimethyl- 2,8,10,11...)
Affinity DataIC50: 0.120nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [1-745,751-1210](Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 790106BDBM790106(2-[(8aR,9R,19E)-1-ethoxy-9,11-dimethyl- 7,8,8a,9,1...)
Affinity DataIC50: 0.130nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [1-745,751-1210](Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 790106BDBM790106(2-[(8aR,9R,19E)-1-ethoxy-9,11-dimethyl- 7,8,8a,9,1...)
Affinity DataIC50: 0.150nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [1-745,751-1210](Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 790007BDBM790007(2-[(10S,17E)-8,10,16-trimethyl-12- (propan-2-yl)-2...)
Affinity DataIC50: 0.170nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [1-745,751-1210](Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 504413BDBM504413(US11040984, Compound 23)
Affinity DataIC50: 0.170nMAssay Description:Buffer formulation: a buffer consisted of 50 mM HEPES (pH 7.5), 0.01% BSA, 5 mM MgCl2, 0.1 mM Orthovanadate. After the buffer was formulated, an enzy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2021
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-745,751-1210](Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 790085BDBM790085((2S)-2-[(10S,17E)-16-ethoxy-19-fluoro- 8,10,12-tri...)
Affinity DataIC50: 0.220nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [1-745,751-1210](Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 504416BDBM504416(US11040984, Compound 33)
Affinity DataIC50: 0.290nMAssay Description:Buffer formulation: a buffer consisted of 50 mM HEPES (pH 7.5), 0.01% BSA, 5 mM MgCl2, 0.1 mM Orthovanadate. After the buffer was formulated, an enzy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2021
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-745,751-1210](Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 790039BDBM790039(2-[(10S,17E)-16-ethoxy-8,10-dimethyl- 12-(propan-2...)
Affinity DataIC50: 0.300nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [1-745,751-1210](Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 790087BDBM790087(2-{(10S,17E)-12-ethyl-19-fluoro-8,10- dimethyl-16-...)
Affinity DataIC50: 0.470nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [1-745,751-1210](Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 790092BDBM790092(2-[(10S,17E)-16-{[1- (methanesulfonyl)azetidin-3-y...)
Affinity DataIC50: 0.550nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [1-745,751-1210](Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 790061BDBM790061(2-[(10S,17E)-16-ethoxy-12-ethyl-8,10- dimethyl-2,8...)
Affinity DataIC50: 0.560nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [1-745,751-1210](Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 790022BDBM790022(2-[(10S,17E)-16-ethyl-8,10,12-trimethyl- 2,8,10,11...)
Affinity DataIC50: 0.580nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [1-745,751-1210](Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 790036BDBM790036(2-{(10S,17E)-8,10,12-trimethyl-16- [(propan-2-yl)o...)
Affinity DataIC50: 0.590nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [1-745,751-1210](Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 790005BDBM790005((10R,16E)-3-methyl-13-(1- methylpiperidin-4-yl)-3,...)
Affinity DataIC50: 0.610nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [1-745,751-1210](Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 790041BDBM790041((2S)-2-[(10S,17E)-16-ethoxy-8,10,12- trimethyl-2,8...)
Affinity DataIC50: 0.620nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [1-745,751-1210](Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 790012BDBM790012(2-[(10S,17E)-16-ethoxy-8,10,12- trimethyl-2,8,10,1...)
Affinity DataIC50: 0.630nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [1-745,751-1210](Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 790086BDBM790086((2S)-2-[(10S,17E)-16-ethoxy-12-ethyl- 19-fluoro-8,...)
Affinity DataIC50: 0.690nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [1-745,751-1210](Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 790110BDBM790110(2-[(8aR,9R,19E)-9,11-dimethyl-1- [(propan-2-yl)oxy...)
Affinity DataIC50: 0.75nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [1-745,751-1210](Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 790080BDBM790080((10S,17E)-16-ethoxy-12-ethyl-19-fluoro- 8,10,14-tr...)
Affinity DataIC50: 0.760nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [1-745,751-1210](Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 790111BDBM790111(2-[(8aR,9R,19E)-22-fluoro-9,11- dimethyl-1-[(propa...)
Affinity DataIC50: 0.950nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [1-745,751-1210](Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 790009BDBM790009(2-[(10S,17E)-19-fluoro-8,10,12,16- tetramethyl-2,8...)
Affinity DataIC50: 1.06nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [1-745,751-1210](Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 789968BDBM789968(2-[(10S,17E)-8,10,12,16-tetramethyl- 2,8,10,11,12,...)
Affinity DataIC50: 1.08nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [1-745,751-1210](Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 790033BDBM790033(2-[(10S,17E)-16-ethoxy-6,8,10-trimethyl- 12-(propa...)
Affinity DataIC50: 1.11nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [1-745,751-1210](Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 790112BDBM790112(2-{(10R,17E)-10-(hydroxymethyl)-8,12- dimethyl-16-...)
Affinity DataIC50: 1.22nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [1-745,751-1210](Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 790117BDBM790117(1-{(10S,17E)-12-ethyl-8,10-dimethyl-16- [(propan-2...)
Affinity DataIC50: 1.28nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [1-745,751-1210](Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 790016BDBM790016((2S)-1-[(10S,17E)-8,10,12,16- tetramethyl-2,8,10,1...)
Affinity DataIC50: 1.30nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [1-745,751-1210](Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 790109BDBM790109(2-[(8aR,9S,19E)-9,11-dimethyl-1- [(propan-2-yl)oxy...)
Affinity DataIC50: 1.31nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [1-745,751-1210](Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 790024BDBM790024((10R,16E)-3-methyl-13-(4- methylpiperazin-1-yl)-3,...)
Affinity DataIC50: 1.65nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [1-745,751-1210](Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 790042BDBM790042((10S,17E)-16-ethoxy-8,10,14-trimethyl- 12-(propan-...)
Affinity DataIC50: 1.77nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [1-745,751-1210](Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 790093BDBM790093(1-[(10S,17E)-16-ethoxy-12-ethyl-8,10- dimethyl-2,8...)
Affinity DataIC50: 1.77nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [1-745,751-1210](Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 790078BDBM790078(2-[(10R,17E)-12-cyclopropyl-16-ethoxy- 6,8,10-trim...)
Affinity DataIC50: 1.85nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [1-745,751-1210](Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 790035BDBM790035((10S,13R,17E)-8,10,12,13,14,16- hexamethyl-2,10,11...)
Affinity DataIC50: 1.88nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [1-745,751-1210](Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 790099BDBM790099((2S)-2-[(10R,17E)-16-ethoxy-19-fluoro- 8,10-dimeth...)
Affinity DataIC50: 1.94nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [1-745,751-1210](Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 790121BDBM790121((2R)-2-{[(10S,17E)-19-fluoro-14-(2- hydroxyethyl)-...)
Affinity DataIC50: 2.01nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [1-745,751-1210](Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 790056BDBM790056(2-[(10S,17E)-16-ethoxy-19-fluoro- 8,10,12-trimethy...)
Affinity DataIC50: 2.10nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [1-745,751-1210](Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 679677BDBM679677(US20240182487, Compound 76)
Affinity DataIC50: 2.20nMAssay Description:Biochemical Assays for Inhibition of Wild-Type and Mutant EGFRs.The inhibitory activities against EGFR WT, EGFR Δ752-759 mutant, EGFR Δ746-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2024
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-745,751-1210](Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 790064BDBM790064(2-{(10S,17E)-19-fluoro-8,10,12- trimethyl-16-[(pro...)
Affinity DataIC50: 2.23nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [1-745,751-1210](Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 679672BDBM679672(US20240182487, Compound 71)
Affinity DataIC50: 2.40nMAssay Description:Biochemical Assays for Inhibition of Wild-Type and Mutant EGFRs.The inhibitory activities against EGFR WT, EGFR Δ752-759 mutant, EGFR Δ746-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2024
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-745,751-1210](Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 790020BDBM790020((2R)-1-[(10S,17E)-8,10,12,16- tetramethyl-2,8,10,1...)
Affinity DataIC50: 2.82nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [1-745,751-1210](Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 679671BDBM679671(US20240182487, Compound 70)
Affinity DataIC50: 2.90nMAssay Description:Biochemical Assays for Inhibition of Wild-Type and Mutant EGFRs.The inhibitory activities against EGFR WT, EGFR Δ752-759 mutant, EGFR Δ746-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2024
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-745,751-1210](Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 790090BDBM790090((2S)-2-{(10S,17E)-12-ethyl-19-fluoro- 8,10-dimethy...)
Affinity DataIC50: 3.02nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

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