Compile Data Set for Download or QSAR
Report error Found 662 Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor [L858R,T790M,C797S]'
TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Suzhou Puhe Biopharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 727115BDBM727115(US20250092017, Compound P39a)
Affinity DataIC50: 0.0500nMAssay Description:The MSA (Mobility Shift Assay) method was used to detect the effects of small molecule inhibitors on the kinase activity of EGFR wild type and its mu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Suzhou Puhe Biopharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 727105BDBM727105(US20250092017, Compound P21)
Affinity DataIC50: 0.0600nMAssay Description:The MSA (Mobility Shift Assay) method was used to detect the effects of small molecule inhibitors on the kinase activity of EGFR wild type and its mu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Suzhou Puhe Biopharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 727113BDBM727113(US20250092017, Compound P29)
Affinity DataIC50: 0.0700nMAssay Description:The MSA (Mobility Shift Assay) method was used to detect the effects of small molecule inhibitors on the kinase activity of EGFR wild type and its mu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Suzhou Puhe Biopharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 727109BDBM727109(US20250092017, Compound P25)
Affinity DataIC50: 0.0800nMAssay Description:The MSA (Mobility Shift Assay) method was used to detect the effects of small molecule inhibitors on the kinase activity of EGFR wild type and its mu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Suzhou Puhe Biopharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 727114BDBM727114(US20250092017, Compound P30)
Affinity DataIC50: 0.100nMAssay Description:The MSA (Mobility Shift Assay) method was used to detect the effects of small molecule inhibitors on the kinase activity of EGFR wild type and its mu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Suzhou Puhe Biopharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 727107BDBM727107(US20250092017, Compound P23)
Affinity DataIC50: 0.110nMAssay Description:The MSA (Mobility Shift Assay) method was used to detect the effects of small molecule inhibitors on the kinase activity of EGFR wild type and its mu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Suzhou Puhe Biopharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 790100BDBM790100(2-{(10S,17E)-12-ethyl-8,10-dimethyl-16- [(propan-2...)
Affinity DataIC50: 0.110nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Suzhou Puhe Biopharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 727098BDBM727098(US20250092017, Compound P14)
Affinity DataIC50: 0.120nMAssay Description:The MSA (Mobility Shift Assay) method was used to detect the effects of small molecule inhibitors on the kinase activity of EGFR wild type and its mu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Suzhou Puhe Biopharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 727118BDBM727118(US20250092017, Compound P51)
Affinity DataIC50: 0.120nMAssay Description:The MSA (Mobility Shift Assay) method was used to detect the effects of small molecule inhibitors on the kinase activity of EGFR wild type and its mu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Suzhou Puhe Biopharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 727108BDBM727108(US20250092017, Compound P24)
Affinity DataIC50: 0.130nMAssay Description:The MSA (Mobility Shift Assay) method was used to detect the effects of small molecule inhibitors on the kinase activity of EGFR wild type and its mu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Suzhou Puhe Biopharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 790092BDBM790092(2-[(10S,17E)-16-{[1- (methanesulfonyl)azetidin-3-y...)
Affinity DataIC50: 0.140nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Suzhou Puhe Biopharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 727125BDBM727125(US20250092017, Compound H7)
Affinity DataIC50: 0.140nMAssay Description:The MSA (Mobility Shift Assay) method was used to detect the effects of small molecule inhibitors on the kinase activity of EGFR wild type and its mu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Suzhou Puhe Biopharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 561454BDBM561454(US11390625, Compound 34 | US11390625, Example 34)
Affinity DataIC50: 0.160nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2022
Entry Details
US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Suzhou Puhe Biopharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 789968BDBM789968(2-[(10S,17E)-8,10,12,16-tetramethyl- 2,8,10,11,12,...)
Affinity DataIC50: 0.170nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Suzhou Puhe Biopharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 790085BDBM790085((2S)-2-[(10S,17E)-16-ethoxy-19-fluoro- 8,10,12-tri...)
Affinity DataIC50: 0.170nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Suzhou Puhe Biopharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 727116BDBM727116(US20250092017, Compound P45)
Affinity DataIC50: 0.180nMAssay Description:The MSA (Mobility Shift Assay) method was used to detect the effects of small molecule inhibitors on the kinase activity of EGFR wild type and its mu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Suzhou Puhe Biopharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 790093BDBM790093(1-[(10S,17E)-16-ethoxy-12-ethyl-8,10- dimethyl-2,8...)
Affinity DataIC50: 0.180nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Suzhou Puhe Biopharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 790106BDBM790106(2-[(8aR,9R,19E)-1-ethoxy-9,11-dimethyl- 7,8,8a,9,1...)
Affinity DataIC50: 0.180nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Suzhou Puhe Biopharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 727135BDBM727135(WO2021133809, Control A | US20250092017, Compound ...)
Affinity DataIC50: 0.190nMAssay Description:The MSA (Mobility Shift Assay) method was used to detect the effects of small molecule inhibitors on the kinase activity of EGFR wild type and its mu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Suzhou Puhe Biopharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 790036BDBM790036(2-{(10S,17E)-8,10,12-trimethyl-16- [(propan-2-yl)o...)
Affinity DataIC50: 0.190nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Suzhou Puhe Biopharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 790084BDBM790084(2-{(11S,17E)-12-cyclopropyl-8,11- dimethyl-16-[(pr...)
Affinity DataIC50: 0.200nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Suzhou Puhe Biopharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 561456BDBM561456(US11390625, Compound 44 | US11390625, Example 44)
Affinity DataIC50: 0.210nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2022
Entry Details
US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Suzhou Puhe Biopharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 790095BDBM790095(2-{(17E)-10-(fluoromethyl)-8,12- dimethyl-16-[(pro...)
Affinity DataIC50: 0.210nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Suzhou Puhe Biopharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 488493BDBM488493(US20250092017, Compound P7)
Affinity DataIC50: 0.210nMAssay Description:The MSA (Mobility Shift Assay) method was used to detect the effects of small molecule inhibitors on the kinase activity of EGFR wild type and its mu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Suzhou Puhe Biopharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 790026BDBM790026(2-[(10S,17E)-12-ethyl-8,10,16-trimethyl- 2,8,10,11...)
Affinity DataIC50: 0.240nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Suzhou Puhe Biopharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 790073BDBM790073(2-[(11S,17E)-12-cyclopropyl-16-ethoxy- 8,11-dimeth...)
Affinity DataIC50: 0.260nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Suzhou Puhe Biopharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 561455BDBM561455(US11390625, Compound 41 | US11390625, Example 41)
Affinity DataIC50: 0.260nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2022
Entry Details
US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Suzhou Puhe Biopharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 495017BDBM495017(US10994015, Example 313 | US10994015, Example 314)
Affinity DataIC50: 0.260nMAssay Description:All compounds and PROTACs were serially diluted in three-fold increments using 100% DMSO, followed by an intermediate 10-fold dilution using Buffer A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2021
Entry Details
US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Suzhou Puhe Biopharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 495012BDBM495012(US10994015, Example 308)
Affinity DataIC50: 0.270nMAssay Description:All compounds and PROTACs were serially diluted in three-fold increments using 100% DMSO, followed by an intermediate 10-fold dilution using Buffer A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2021
Entry Details
US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Suzhou Puhe Biopharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 790106BDBM790106(2-[(8aR,9R,19E)-1-ethoxy-9,11-dimethyl- 7,8,8a,9,1...)
Affinity DataIC50: 0.280nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Suzhou Puhe Biopharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 727100BDBM727100(US20250092017, Compound P16)
Affinity DataIC50: 0.280nMAssay Description:The MSA (Mobility Shift Assay) method was used to detect the effects of small molecule inhibitors on the kinase activity of EGFR wild type and its mu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Suzhou Puhe Biopharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 727124BDBM727124(US20250092017, Compound H6)
Affinity DataIC50: 0.300nMAssay Description:The MSA (Mobility Shift Assay) method was used to detect the effects of small molecule inhibitors on the kinase activity of EGFR wild type and its mu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Suzhou Puhe Biopharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 727122BDBM727122(US20250092017, Compound H4)
Affinity DataIC50: 0.300nMAssay Description:The MSA (Mobility Shift Assay) method was used to detect the effects of small molecule inhibitors on the kinase activity of EGFR wild type and its mu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Suzhou Puhe Biopharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 790022BDBM790022(2-[(10S,17E)-16-ethyl-8,10,12-trimethyl- 2,8,10,11...)
Affinity DataIC50: 0.330nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Suzhou Puhe Biopharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 790068BDBM790068((10S,17E)-16-{[3- (methanesulfonyl)cyclobutyl]oxy}...)
Affinity DataIC50: 0.330nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Suzhou Puhe Biopharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 727111BDBM727111(US20250092017, Compound P28)
Affinity DataIC50: 0.340nMAssay Description:The MSA (Mobility Shift Assay) method was used to detect the effects of small molecule inhibitors on the kinase activity of EGFR wild type and its mu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Suzhou Puhe Biopharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 790094BDBM790094(2-{(10S,13R,17E)-8,10,12,13- tetramethyl-16-[(prop...)
Affinity DataIC50: 0.340nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Suzhou Puhe Biopharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 727129BDBM727129(US20250092017, Compound H10)
Affinity DataIC50: 0.340nMAssay Description:The MSA (Mobility Shift Assay) method was used to detect the effects of small molecule inhibitors on the kinase activity of EGFR wild type and its mu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Suzhou Puhe Biopharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 495016BDBM495016(US10994015, Example 312)
Affinity DataIC50: 0.350nMAssay Description:All compounds and PROTACs were serially diluted in three-fold increments using 100% DMSO, followed by an intermediate 10-fold dilution using Buffer A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2021
Entry Details
US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Suzhou Puhe Biopharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 790097BDBM790097((2S)-1-{(10R,17E)-12-ethyl-8,10- dimethyl-16-[(pro...)
Affinity DataIC50: 0.360nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Suzhou Puhe Biopharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 790087BDBM790087(2-{(10S,17E)-12-ethyl-19-fluoro-8,10- dimethyl-16-...)
Affinity DataIC50: 0.370nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Suzhou Puhe Biopharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 790038BDBM790038((10S,17E)-16-{[1- (methanesulfonyl)azetidin-3-yl]o...)
Affinity DataIC50: 0.370nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Suzhou Puhe Biopharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 727134BDBM727134(US20250092017, Compound H19)
Affinity DataIC50: 0.400nMAssay Description:The MSA (Mobility Shift Assay) method was used to detect the effects of small molecule inhibitors on the kinase activity of EGFR wild type and its mu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Suzhou Puhe Biopharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 727119BDBM727119(US20250092017, Compound H1)
Affinity DataIC50: 0.400nMAssay Description:The MSA (Mobility Shift Assay) method was used to detect the effects of small molecule inhibitors on the kinase activity of EGFR wild type and its mu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Suzhou Puhe Biopharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 790083BDBM790083(2-{(10R,17E)-12-cyclopropyl-8,10- dimethyl-16-[(pr...)
Affinity DataIC50: 0.420nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Suzhou Puhe Biopharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 727104BDBM727104(US20250092017, Compound P20)
Affinity DataIC50: 0.420nMAssay Description:The MSA (Mobility Shift Assay) method was used to detect the effects of small molecule inhibitors on the kinase activity of EGFR wild type and its mu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Suzhou Puhe Biopharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 727123BDBM727123(US20250092017, Compound H5)
Affinity DataIC50: 0.430nMAssay Description:The MSA (Mobility Shift Assay) method was used to detect the effects of small molecule inhibitors on the kinase activity of EGFR wild type and its mu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Suzhou Puhe Biopharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 727131BDBM727131(US20250092017, Compound H12)
Affinity DataIC50: 0.430nMAssay Description:The MSA (Mobility Shift Assay) method was used to detect the effects of small molecule inhibitors on the kinase activity of EGFR wild type and its mu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Suzhou Puhe Biopharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 790020BDBM790020((2R)-1-[(10S,17E)-8,10,12,16- tetramethyl-2,8,10,1...)
Affinity DataIC50: 0.430nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Suzhou Puhe Biopharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 727130BDBM727130(US20250092017, Compound H11)
Affinity DataIC50: 0.440nMAssay Description:The MSA (Mobility Shift Assay) method was used to detect the effects of small molecule inhibitors on the kinase activity of EGFR wild type and its mu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
US Patent

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