Compile Data Set for Download or QSAR
Report error Found 1529 Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor [T790M,L858R]'
TargetEpidermal growth factor receptor [T790M,L858R](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 717530BDBM717530(US20250034165, Example 79)
Affinity DataIC50: 0.00700nMAssay Description:A 50 ng/μL EGFR (L858R/T790M, Carna) stock solution was diluted with a kinase buffer (50 mM HEPES, 10 mM MgCl2, 2 mM DTT, 1 mM EGTA, 0.01% Tween 20),...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 717526BDBM717526(US20250034165, Example 63)
Affinity DataIC50: 0.00900nMAssay Description:A 50 ng/μL EGFR (L858R/T790M, Carna) stock solution was diluted with a kinase buffer (50 mM HEPES, 10 mM MgCl2, 2 mM DTT, 1 mM EGTA, 0.01% Tween 20),...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 717507BDBM717507(US20250034165, Example 44)
Affinity DataIC50: 0.0100nMAssay Description:A 50 ng/μL EGFR (L858R/T790M, Carna) stock solution was diluted with a kinase buffer (50 mM HEPES, 10 mM MgCl2, 2 mM DTT, 1 mM EGTA, 0.01% Tween 20),...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 717537BDBM717537(US20250034165, Example 88)
Affinity DataIC50: 0.0100nMAssay Description:A 50 ng/μL EGFR (L858R/T790M, Carna) stock solution was diluted with a kinase buffer (50 mM HEPES, 10 mM MgCl2, 2 mM DTT, 1 mM EGTA, 0.01% Tween 20),...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 717520BDBM717520(US20250034165, Example 57)
Affinity DataIC50: 0.0110nMAssay Description:A 50 ng/μL EGFR (L858R/T790M, Carna) stock solution was diluted with a kinase buffer (50 mM HEPES, 10 mM MgCl2, 2 mM DTT, 1 mM EGTA, 0.01% Tween 20),...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 717491BDBM717491(US20250034165, Example 28)
Affinity DataIC50: 0.0110nMAssay Description:A 50 ng/μL EGFR (L858R/T790M, Carna) stock solution was diluted with a kinase buffer (50 mM HEPES, 10 mM MgCl2, 2 mM DTT, 1 mM EGTA, 0.01% Tween 20),...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 717516BDBM717516(US20250034165, Example 53)
Affinity DataIC50: 0.0110nMAssay Description:A 50 ng/μL EGFR (L858R/T790M, Carna) stock solution was diluted with a kinase buffer (50 mM HEPES, 10 mM MgCl2, 2 mM DTT, 1 mM EGTA, 0.01% Tween 20),...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 717480BDBM717480(US20250034165, Example 17)
Affinity DataIC50: 0.0110nMAssay Description:A 50 ng/μL EGFR (L858R/T790M, Carna) stock solution was diluted with a kinase buffer (50 mM HEPES, 10 mM MgCl2, 2 mM DTT, 1 mM EGTA, 0.01% Tween 20),...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 717521BDBM717521(US20250034165, Example 58)
Affinity DataIC50: 0.0120nMAssay Description:A 50 ng/μL EGFR (L858R/T790M, Carna) stock solution was diluted with a kinase buffer (50 mM HEPES, 10 mM MgCl2, 2 mM DTT, 1 mM EGTA, 0.01% Tween 20),...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 717505BDBM717505(US20250034165, Example 42)
Affinity DataIC50: 0.0130nMAssay Description:A 50 ng/μL EGFR (L858R/T790M, Carna) stock solution was diluted with a kinase buffer (50 mM HEPES, 10 mM MgCl2, 2 mM DTT, 1 mM EGTA, 0.01% Tween 20),...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 717496BDBM717496(US20250034165, Example 33)
Affinity DataIC50: 0.0150nMAssay Description:A 50 ng/μL EGFR (L858R/T790M, Carna) stock solution was diluted with a kinase buffer (50 mM HEPES, 10 mM MgCl2, 2 mM DTT, 1 mM EGTA, 0.01% Tween 20),...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 717528BDBM717528(US20250034165, Example 70)
Affinity DataIC50: 0.0150nMAssay Description:A 50 ng/μL EGFR (L858R/T790M, Carna) stock solution was diluted with a kinase buffer (50 mM HEPES, 10 mM MgCl2, 2 mM DTT, 1 mM EGTA, 0.01% Tween 20),...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 717519BDBM717519(US20250034165, Example 56)
Affinity DataIC50: 0.0160nMAssay Description:A 50 ng/μL EGFR (L858R/T790M, Carna) stock solution was diluted with a kinase buffer (50 mM HEPES, 10 mM MgCl2, 2 mM DTT, 1 mM EGTA, 0.01% Tween 20),...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 717483BDBM717483(US20250034165, Example 20)
Affinity DataIC50: 0.0160nMAssay Description:A 50 ng/μL EGFR (L858R/T790M, Carna) stock solution was diluted with a kinase buffer (50 mM HEPES, 10 mM MgCl2, 2 mM DTT, 1 mM EGTA, 0.01% Tween 20),...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 717517BDBM717517(US20250034165, Example 54)
Affinity DataIC50: 0.0170nMAssay Description:A 50 ng/μL EGFR (L858R/T790M, Carna) stock solution was diluted with a kinase buffer (50 mM HEPES, 10 mM MgCl2, 2 mM DTT, 1 mM EGTA, 0.01% Tween 20),...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 717509BDBM717509(US20250034165, Example 46)
Affinity DataIC50: 0.0170nMAssay Description:A 50 ng/μL EGFR (L858R/T790M, Carna) stock solution was diluted with a kinase buffer (50 mM HEPES, 10 mM MgCl2, 2 mM DTT, 1 mM EGTA, 0.01% Tween 20),...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 717518BDBM717518(US20250034165, Example 55)
Affinity DataIC50: 0.0170nMAssay Description:A 50 ng/μL EGFR (L858R/T790M, Carna) stock solution was diluted with a kinase buffer (50 mM HEPES, 10 mM MgCl2, 2 mM DTT, 1 mM EGTA, 0.01% Tween 20),...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 717514BDBM717514(US20250034165, Example 51)
Affinity DataIC50: 0.0170nMAssay Description:A 50 ng/μL EGFR (L858R/T790M, Carna) stock solution was diluted with a kinase buffer (50 mM HEPES, 10 mM MgCl2, 2 mM DTT, 1 mM EGTA, 0.01% Tween 20),...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 717504BDBM717504(US20250034165, Example 41)
Affinity DataIC50: 0.0180nMAssay Description:A 50 ng/μL EGFR (L858R/T790M, Carna) stock solution was diluted with a kinase buffer (50 mM HEPES, 10 mM MgCl2, 2 mM DTT, 1 mM EGTA, 0.01% Tween 20),...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 717495BDBM717495(US20250034165, Example 32)
Affinity DataIC50: 0.0180nMAssay Description:A 50 ng/μL EGFR (L858R/T790M, Carna) stock solution was diluted with a kinase buffer (50 mM HEPES, 10 mM MgCl2, 2 mM DTT, 1 mM EGTA, 0.01% Tween 20),...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 717492BDBM717492(US20250034165, Example 29)
Affinity DataIC50: 0.0190nMAssay Description:A 50 ng/μL EGFR (L858R/T790M, Carna) stock solution was diluted with a kinase buffer (50 mM HEPES, 10 mM MgCl2, 2 mM DTT, 1 mM EGTA, 0.01% Tween 20),...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 717533BDBM717533(US20250034165, Example 82)
Affinity DataIC50: 0.0200nMAssay Description:A 50 ng/μL EGFR (L858R/T790M, Carna) stock solution was diluted with a kinase buffer (50 mM HEPES, 10 mM MgCl2, 2 mM DTT, 1 mM EGTA, 0.01% Tween 20),...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 717508BDBM717508(US20250034165, Example 45)
Affinity DataIC50: 0.0200nMAssay Description:A 50 ng/μL EGFR (L858R/T790M, Carna) stock solution was diluted with a kinase buffer (50 mM HEPES, 10 mM MgCl2, 2 mM DTT, 1 mM EGTA, 0.01% Tween 20),...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 717473BDBM717473(US20250034165, Example 10)
Affinity DataIC50: 0.0200nMAssay Description:A 50 ng/μL EGFR (L858R/T790M, Carna) stock solution was diluted with a kinase buffer (50 mM HEPES, 10 mM MgCl2, 2 mM DTT, 1 mM EGTA, 0.01% Tween 20),...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 717488BDBM717488(US20250034165, Example 25)
Affinity DataIC50: 0.0210nMAssay Description:A 50 ng/μL EGFR (L858R/T790M, Carna) stock solution was diluted with a kinase buffer (50 mM HEPES, 10 mM MgCl2, 2 mM DTT, 1 mM EGTA, 0.01% Tween 20),...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 717467BDBM717467(US20250034165, Example 1)
Affinity DataIC50: 0.0220nMAssay Description:A 50 ng/μL EGFR (L858R/T790M, Carna) stock solution was diluted with a kinase buffer (50 mM HEPES, 10 mM MgCl2, 2 mM DTT, 1 mM EGTA, 0.01% Tween 20),...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 717510BDBM717510(US20250034165, Example 47)
Affinity DataIC50: 0.0230nMAssay Description:A 50 ng/μL EGFR (L858R/T790M, Carna) stock solution was diluted with a kinase buffer (50 mM HEPES, 10 mM MgCl2, 2 mM DTT, 1 mM EGTA, 0.01% Tween 20),...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 717511BDBM717511(US20250034165, Example 48)
Affinity DataIC50: 0.0230nMAssay Description:A 50 ng/μL EGFR (L858R/T790M, Carna) stock solution was diluted with a kinase buffer (50 mM HEPES, 10 mM MgCl2, 2 mM DTT, 1 mM EGTA, 0.01% Tween 20),...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 717489BDBM717489(US20250034165, Example 26)
Affinity DataIC50: 0.0250nMAssay Description:A 50 ng/μL EGFR (L858R/T790M, Carna) stock solution was diluted with a kinase buffer (50 mM HEPES, 10 mM MgCl2, 2 mM DTT, 1 mM EGTA, 0.01% Tween 20),...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 717506BDBM717506(US20250034165, Example 43)
Affinity DataIC50: 0.0260nMAssay Description:A 50 ng/μL EGFR (L858R/T790M, Carna) stock solution was diluted with a kinase buffer (50 mM HEPES, 10 mM MgCl2, 2 mM DTT, 1 mM EGTA, 0.01% Tween 20),...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 717515BDBM717515(US20250034165, Example 52)
Affinity DataIC50: 0.0260nMAssay Description:A 50 ng/μL EGFR (L858R/T790M, Carna) stock solution was diluted with a kinase buffer (50 mM HEPES, 10 mM MgCl2, 2 mM DTT, 1 mM EGTA, 0.01% Tween 20),...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 717478BDBM717478(US20250034165, Example 15)
Affinity DataIC50: 0.0270nMAssay Description:A 50 ng/μL EGFR (L858R/T790M, Carna) stock solution was diluted with a kinase buffer (50 mM HEPES, 10 mM MgCl2, 2 mM DTT, 1 mM EGTA, 0.01% Tween 20),...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 717468BDBM717468(US20250034165, Example 3)
Affinity DataIC50: 0.0270nMAssay Description:A 50 ng/μL EGFR (L858R/T790M, Carna) stock solution was diluted with a kinase buffer (50 mM HEPES, 10 mM MgCl2, 2 mM DTT, 1 mM EGTA, 0.01% Tween 20),...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 717500BDBM717500(US20250034165, Example 37)
Affinity DataIC50: 0.0270nMAssay Description:A 50 ng/μL EGFR (L858R/T790M, Carna) stock solution was diluted with a kinase buffer (50 mM HEPES, 10 mM MgCl2, 2 mM DTT, 1 mM EGTA, 0.01% Tween 20),...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 717503BDBM717503(US20250034165, Example 40)
Affinity DataIC50: 0.0270nMAssay Description:A 50 ng/μL EGFR (L858R/T790M, Carna) stock solution was diluted with a kinase buffer (50 mM HEPES, 10 mM MgCl2, 2 mM DTT, 1 mM EGTA, 0.01% Tween 20),...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 717497BDBM717497(US20250034165, Example 34)
Affinity DataIC50: 0.0280nMAssay Description:A 50 ng/μL EGFR (L858R/T790M, Carna) stock solution was diluted with a kinase buffer (50 mM HEPES, 10 mM MgCl2, 2 mM DTT, 1 mM EGTA, 0.01% Tween 20),...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 717482BDBM717482(US20250034165, Example 19)
Affinity DataIC50: 0.0280nMAssay Description:A 50 ng/μL EGFR (L858R/T790M, Carna) stock solution was diluted with a kinase buffer (50 mM HEPES, 10 mM MgCl2, 2 mM DTT, 1 mM EGTA, 0.01% Tween 20),...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 717471BDBM717471(US20250034165, Example 8)
Affinity DataIC50: 0.0290nMAssay Description:A 50 ng/μL EGFR (L858R/T790M, Carna) stock solution was diluted with a kinase buffer (50 mM HEPES, 10 mM MgCl2, 2 mM DTT, 1 mM EGTA, 0.01% Tween 20),...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 717486BDBM717486(US20250034165, Example 23)
Affinity DataIC50: 0.0290nMAssay Description:A 50 ng/μL EGFR (L858R/T790M, Carna) stock solution was diluted with a kinase buffer (50 mM HEPES, 10 mM MgCl2, 2 mM DTT, 1 mM EGTA, 0.01% Tween 20),...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 717490BDBM717490(US20250034165, Example 27)
Affinity DataIC50: 0.0300nMAssay Description:A 50 ng/μL EGFR (L858R/T790M, Carna) stock solution was diluted with a kinase buffer (50 mM HEPES, 10 mM MgCl2, 2 mM DTT, 1 mM EGTA, 0.01% Tween 20),...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 717498BDBM717498(US20250034165, Example 35)
Affinity DataIC50: 0.0300nMAssay Description:A 50 ng/μL EGFR (L858R/T790M, Carna) stock solution was diluted with a kinase buffer (50 mM HEPES, 10 mM MgCl2, 2 mM DTT, 1 mM EGTA, 0.01% Tween 20),...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 717487BDBM717487(US20250034165, Example 24)
Affinity DataIC50: 0.0310nMAssay Description:A 50 ng/μL EGFR (L858R/T790M, Carna) stock solution was diluted with a kinase buffer (50 mM HEPES, 10 mM MgCl2, 2 mM DTT, 1 mM EGTA, 0.01% Tween 20),...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 717525BDBM717525(US20250034165, Example 62)
Affinity DataIC50: 0.0310nMAssay Description:A 50 ng/μL EGFR (L858R/T790M, Carna) stock solution was diluted with a kinase buffer (50 mM HEPES, 10 mM MgCl2, 2 mM DTT, 1 mM EGTA, 0.01% Tween 20),...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 717531BDBM717531(US20250034165, Example 80)
Affinity DataIC50: 0.0310nMAssay Description:A 50 ng/μL EGFR (L858R/T790M, Carna) stock solution was diluted with a kinase buffer (50 mM HEPES, 10 mM MgCl2, 2 mM DTT, 1 mM EGTA, 0.01% Tween 20),...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 717499BDBM717499(US20250034165, Example 36)
Affinity DataIC50: 0.0330nMAssay Description:A 50 ng/μL EGFR (L858R/T790M, Carna) stock solution was diluted with a kinase buffer (50 mM HEPES, 10 mM MgCl2, 2 mM DTT, 1 mM EGTA, 0.01% Tween 20),...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 313222BDBM313222(N-[3-[[2-[4-(4-ethylpiperazin-1-yl)anilino]-5-(tri...)
Affinity DataKd:  0.0370nMAssay Description:Kinase-tagged T7 phage strains were prepared in an E. coli host derived from the BL21 strain. E. coli were grown to log-phase and infected with T7 ph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 717494BDBM717494(US20250034165, Example 31)
Affinity DataIC50: 0.0380nMAssay Description:A 50 ng/μL EGFR (L858R/T790M, Carna) stock solution was diluted with a kinase buffer (50 mM HEPES, 10 mM MgCl2, 2 mM DTT, 1 mM EGTA, 0.01% Tween 20),...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 717529BDBM717529(US20250034165, Example 72)
Affinity DataIC50: 0.0380nMAssay Description:A 50 ng/μL EGFR (L858R/T790M, Carna) stock solution was diluted with a kinase buffer (50 mM HEPES, 10 mM MgCl2, 2 mM DTT, 1 mM EGTA, 0.01% Tween 20),...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 717485BDBM717485(US20250034165, Example 22)
Affinity DataIC50: 0.0400nMAssay Description:A 50 ng/μL EGFR (L858R/T790M, Carna) stock solution was diluted with a kinase buffer (50 mM HEPES, 10 mM MgCl2, 2 mM DTT, 1 mM EGTA, 0.01% Tween 20),...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandChemical structure of BindingDB Monomer ID 717481BDBM717481(US20250034165, Example 18)
Affinity DataIC50: 0.0400nMAssay Description:A 50 ng/μL EGFR (L858R/T790M, Carna) stock solution was diluted with a kinase buffer (50 mM HEPES, 10 mM MgCl2, 2 mM DTT, 1 mM EGTA, 0.01% Tween 20),...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

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