Compile Data Set for Download or QSAR
Report error Found 37 Enz. Inhib. hit(s) with Target = 'Estradiol 17-beta-dehydrogenase 1'
TargetEstradiol 17-beta-dehydrogenase 1(Rat)
Elexopharm

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50515434BDBM50515434(CHEMBL4518587)
Affinity DataIC50: 9nMAssay Description:Inhibition of recombinant rat 17beta-HSD1 expressed in HEK293 cells using [3H]-E1 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetEstradiol 17-beta-dehydrogenase 1(Rat)
Elexopharm

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50126972BDBM50126972(CHEMBL3629586)
Affinity DataIC50: 80nMAssay Description:Inhibition of recombinant rat 17beta HSD1 expressed in HEK293 cells using unlabeled- and labelled [2,4,6,7-3H]-E1 as substrate incubated for 10 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetEstradiol 17-beta-dehydrogenase 1(Rat)
Elexopharm

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50126973BDBM50126973(CHEMBL3629587)
Affinity DataIC50: 97nMAssay Description:Inhibition of recombinant rat 17beta HSD1 expressed in HEK293 cells using unlabeled- and labelled [2,4,6,7-3H]-E1 as substrate incubated for 10 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2016
Entry Details Article
PubMed
TargetEstradiol 17-beta-dehydrogenase 11(Homo sapiens)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 50632086BDBM50632086(CHEMBL5394877 | US20250340546, Example 8)
Affinity DataIC50: 263nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2026
Entry Details US Patent

TargetEstradiol 17-beta-dehydrogenase 1(Rat)
Elexopharm

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50515436BDBM50515436(CHEMBL4441313)
Affinity DataIC50: 350nMAssay Description:Inhibition of recombinant rat 17beta-HSD1 expressed in HEK293 cells using [3H]-E1 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetEstradiol 17-beta-dehydrogenase 1(Rat)
Elexopharm

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50515435BDBM50515435(CHEMBL4513439)
Affinity DataIC50: 388nMAssay Description:Inhibition of recombinant rat 17beta-HSD1 expressed in HEK293 cells using [3H]-E1 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetEstradiol 17-beta-dehydrogenase 11(Homo sapiens)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 50365463BDBM50365463(CHEMBL1232461)
Affinity DataIC50: 620nMAssay Description:Inhibition of HSD17B11 (unknown origin) incubated for 1 hr by colloidal coomassie staining based LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEstradiol 17-beta-dehydrogenase 11(Homo sapiens)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 784428BDBM784428(US20250340546, Example 29)
Affinity DataIC50: 991nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/25/2026
Entry Details US Patent

TargetEstradiol 17-beta-dehydrogenase 11(Homo sapiens)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 784419BDBM784419(US20250340546, Example 20)
Affinity DataIC50: 992nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/25/2026
Entry Details US Patent

TargetEstradiol 17-beta-dehydrogenase 11(Homo sapiens)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 784427BDBM784427(US20250340546, Example 28)
Affinity DataIC50: 1.11E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/25/2026
Entry Details US Patent

TargetEstradiol 17-beta-dehydrogenase 11(Homo sapiens)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 784418BDBM784418(US20250340546, Example 19)
Affinity DataIC50: 1.21E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/25/2026
Entry Details US Patent

TargetEstradiol 17-beta-dehydrogenase 1(Rat)
Elexopharm

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50515432BDBM50515432(CHEMBL4447938)
Affinity DataIC50: 1.33E+3nMAssay Description:Inhibition of recombinant rat 17beta-HSD1 expressed in HEK293 cells using [3H]-E1 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetEstradiol 17-beta-dehydrogenase 11(Homo sapiens)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 784422BDBM784422(US20250340546, Example 23)
Affinity DataIC50: 1.74E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/25/2026
Entry Details US Patent

TargetEstradiol 17-beta-dehydrogenase 11(Homo sapiens)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 50632088BDBM50632088(CHEMBL5411903 | US20250340546, Example 30)
Affinity DataIC50: 2.26E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2026
Entry Details US Patent

TargetEstradiol 17-beta-dehydrogenase 11(Homo sapiens)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 784423BDBM784423(US20250340546, Example 24)
Affinity DataIC50: 2.52E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/25/2026
Entry Details US Patent

TargetEstradiol 17-beta-dehydrogenase 11(Homo sapiens)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 50632079BDBM50632079(CHEMBL5414092 | US20250340546, Example 15)
Affinity DataIC50: 3.26E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2026
Entry Details US Patent

TargetEstradiol 17-beta-dehydrogenase 11(Homo sapiens)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 784413BDBM784413(US20250340546, Example 14)
Affinity DataIC50: 3.54E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/25/2026
Entry Details US Patent

TargetEstradiol 17-beta-dehydrogenase 11(Homo sapiens)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 50632090BDBM50632090(CHEMBL5426101 | US20250340546, Example 1)
Affinity DataIC50: 4.21E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2026
Entry Details US Patent

TargetEstradiol 17-beta-dehydrogenase 11(Homo sapiens)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 784421BDBM784421(US20250340546, Example 22)
Affinity DataIC50: 5.04E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/25/2026
Entry Details US Patent

TargetEstradiol 17-beta-dehydrogenase 11(Homo sapiens)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 784415BDBM784415(US20250340546, Example 16)
Affinity DataIC50: 5.90E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/25/2026
Entry Details US Patent

TargetEstradiol 17-beta-dehydrogenase 11(Homo sapiens)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 784410BDBM784410(US20250340546, Example 11)
Affinity DataIC50: 5.94E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/25/2026
Entry Details US Patent

TargetEstradiol 17-beta-dehydrogenase 11(Homo sapiens)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 50632076BDBM50632076(CHEMBL5405439 | US20250340546, Example 9)
Affinity DataIC50: 6.09E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2026
Entry Details US Patent

TargetEstradiol 17-beta-dehydrogenase 11(Homo sapiens)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 784420BDBM784420(US20250340546, Example 21)
Affinity DataIC50: 6.32E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/25/2026
Entry Details US Patent

TargetEstradiol 17-beta-dehydrogenase 11(Homo sapiens)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 784426BDBM784426(US20250340546, Example 27)
Affinity DataIC50: 6.64E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/25/2026
Entry Details US Patent

TargetEstradiol 17-beta-dehydrogenase 11(Homo sapiens)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 50632078BDBM50632078(CHEMBL5429503 | US20250340546, Example 18)
Affinity DataIC50: 7.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2026
Entry Details US Patent

TargetEstradiol 17-beta-dehydrogenase 11(Homo sapiens)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 50632084BDBM50632084(CHEMBL5423975 | US20250340546, Example 10)
Affinity DataIC50: 8.26E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2026
Entry Details US Patent

TargetEstradiol 17-beta-dehydrogenase 11(Homo sapiens)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 784401BDBM784401(US20250340546, Example 2)
Affinity DataIC50: 8.61E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/25/2026
Entry Details US Patent

TargetEstradiol 17-beta-dehydrogenase 11(Homo sapiens)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 50632085BDBM50632085(CHEMBL5405782 | US20250340546, Example 6)
Affinity DataIC50: 8.63E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2026
Entry Details US Patent

TargetEstradiol 17-beta-dehydrogenase 11(Homo sapiens)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 784416BDBM784416(US20250340546, Example 17)
Affinity DataIC50: 8.69E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/25/2026
Entry Details US Patent

TargetEstradiol 17-beta-dehydrogenase 11(Homo sapiens)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 50632044BDBM50632044(CHEMBL5417785)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human full-length C-terminal His-tagged HSD17B11 using estradiol and NAD as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetEstradiol 17-beta-dehydrogenase 11(Homo sapiens)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 50632089BDBM50632089(CHEMBL5307400 | US20250340546, Example 7)
Affinity DataIC50: 1.00E+4nMAssay Description:Uncompetitive inhibition of recombinant human full-length C-terminal His-tagged HSD17B11 using estradiol and NAD as substrate preincubated for 10 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetEstradiol 17-beta-dehydrogenase 11(Homo sapiens)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 784425BDBM784425(US20250340546, Example 26)
Affinity DataIC50: 1.02E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/25/2026
Entry Details US Patent

TargetEstradiol 17-beta-dehydrogenase 11(Homo sapiens)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 784403BDBM784403(US20250340546, Example 4)
Affinity DataIC50: 1.03E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/25/2026
Entry Details US Patent

TargetEstradiol 17-beta-dehydrogenase 11(Homo sapiens)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 784424BDBM784424(US20250340546, Example 25)
Affinity DataIC50: 1.03E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/25/2026
Entry Details US Patent

TargetEstradiol 17-beta-dehydrogenase 11(Homo sapiens)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 50632087BDBM50632087(CHEMBL5417980 | US20250340546, Example 13)
Affinity DataIC50: 1.03E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2026
Entry Details US Patent

TargetEstradiol 17-beta-dehydrogenase 11(Homo sapiens)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 50632089BDBM50632089(CHEMBL5307400 | US20250340546, Example 7)
Affinity DataIC50: 1.03E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2026
Entry Details US Patent

TargetEstradiol 17-beta-dehydrogenase 11(Homo sapiens)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 784411BDBM784411(US20250340546, Example 12)
Affinity DataIC50: 1.03E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/25/2026
Entry Details US Patent