Compile Data Set for Download or QSAR
Report error Found 21 Enz. Inhib. hit(s) with Target = 'G2/mitotic-specific cyclin-B'
TargetG2/mitotic-specific cyclin-B1(Rat)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50140090BDBM50140090(RDPCCSNPVCTVHNPQIC* | CHEMBL217150)
Affinity DataIC50: 12.6nMAssay Description:Compound was evaluated for inhibition of rat Nicotinic acetylcholine receptor alpha7 (nAChR) in Xenopus OocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetG2/mitotic-specific cyclin-B1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50246253BDBM50246253(AZD-5438 | 4-(1-isopropyl-2-methyl-1H-imidazol-5-y...)
Affinity DataIC50: 16nMAssay Description:Inhibition of Cyclin B1/CDK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetG2/mitotic-specific cyclin-B(Starfish)TBA
LigandChemical structure of BindingDB Monomer ID 50488796BDBM50488796(CHEMBL2295954)
Affinity DataIC50: 17nMAssay Description:Inhibition of Asteroidea (starfish) Cyclin-dependent kinase 1/cyclin B isolated from oocyte using histone H1 and [gamma33P]ATP as substrate after 30 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article

TargetG2/mitotic-specific cyclin-B(Starfish)TBA
LigandChemical structure of BindingDB Monomer ID 50488820BDBM50488820(CHEMBL2295952)
Affinity DataIC50: 40nMAssay Description:Inhibition of Asteroidea (starfish) Cyclin-dependent kinase 1/cyclin B isolated from oocyte using histone H1 and [gamma33P]ATP as substrate after 30 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article

TargetG2/mitotic-specific cyclin-B1(Rat)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50140091BDBM50140091(IRDgammaCCSNPACRVNNOHVC# | CHEMBL413505)
Affinity DataIC50: 48nMAssay Description:Compound was evaluated for inhibition of rat Nicotinic acetylcholine receptor alpha7 (nAChR) in Xenopus OocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetG2/mitotic-specific cyclin-B(Starfish)TBA
LigandChemical structure of BindingDB Monomer ID 50488808BDBM50488808(CHEMBL2295953)
Affinity DataIC50: 70nMAssay Description:Inhibition of Asteroidea (starfish) Cyclin-dependent kinase 1/cyclin B isolated from oocyte using histone H1 and [gamma33P]ATP as substrate after 30 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article

TargetG2/mitotic-specific cyclin-B(Starfish)TBA
LigandChemical structure of BindingDB Monomer ID 50488813BDBM50488813(CHEMBL2295943)
Affinity DataIC50: 130nMAssay Description:Inhibition of Asteroidea (starfish) Cyclin-dependent kinase 1/cyclin B isolated from oocyte using histone H1 and [gamma33P]ATP as substrate after 30 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article

TargetG2/mitotic-specific cyclin-B1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50652792BDBM50652792(CHEMBL3752910)
Affinity DataKd:  157nMAssay Description:Binding affinity to human CCNB1 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetG2/mitotic-specific cyclin-B(Starfish)TBA
LigandChemical structure of BindingDB Monomer ID 50488809BDBM50488809(CHEMBL2295947)
Affinity DataIC50: 180nMAssay Description:Inhibition of Asteroidea (starfish) Cyclin-dependent kinase 1/cyclin B isolated from oocyte using histone H1 and [gamma33P]ATP as substrate after 30 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article

TargetG2/mitotic-specific cyclin-B1(Rat)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50140085BDBM50140085(GCCSLPPCAANNPDYC* | CHEMBL266702)
Affinity DataIC50: 252nMAssay Description:Compound was evaluated for inhibition of rat Nicotinic acetylcholine receptor alpha7 (nAChR) in Xenopus OocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetG2/mitotic-specific cyclin-B(Starfish)TBA
LigandChemical structure of BindingDB Monomer ID 50488800BDBM50488800(CHEMBL2295955)
Affinity DataIC50: 270nMAssay Description:Inhibition of Asteroidea (starfish) Cyclin-dependent kinase 1/cyclin B isolated from oocyte using histone H1 and [gamma33P]ATP as substrate after 30 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article

TargetG2/mitotic-specific cyclin-B(Starfish)TBA
LigandChemical structure of BindingDB Monomer ID 50488798BDBM50488798(CHEMBL2295944)
Affinity DataIC50: 300nMAssay Description:Inhibition of Asteroidea (starfish) Cyclin-dependent kinase 1/cyclin B isolated from oocyte using histone H1 and [gamma33P]ATP as substrate after 30 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article

TargetG2/mitotic-specific cyclin-B(Starfish)TBA
LigandChemical structure of BindingDB Monomer ID 50488812BDBM50488812(CHEMBL2295960)
Affinity DataIC50: 300nMAssay Description:Inhibition of Asteroidea (starfish) Cyclin-dependent kinase 1/cyclin B isolated from oocyte using histone H1 and [gamma33P]ATP as substrate after 30 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article

TargetG2/mitotic-specific cyclin-B1(Rat)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50140088BDBM50140088(GGCCSHPACAANNQDYC# | CHEMBL451251)
Affinity DataIC50: 367nMAssay Description:Compound was evaluated for inhibition of rat Nicotinic acetylcholine receptor alpha7 (nAChR) in Xenopus OocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetG2/mitotic-specific cyclin-B(Starfish)TBA
LigandChemical structure of BindingDB Monomer ID 50488803BDBM50488803(CHEMBL2295948)
Affinity DataIC50: 500nMAssay Description:Inhibition of Asteroidea (starfish) Cyclin-dependent kinase 1/cyclin B isolated from oocyte using histone H1 and [gamma33P]ATP as substrate after 30 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article

TargetG2/mitotic-specific cyclin-B(Starfish)TBA
LigandChemical structure of BindingDB Monomer ID 50488797BDBM50488797(CHEMBL2295936)
Affinity DataIC50: 730nMAssay Description:Inhibition of Asteroidea (starfish) Cyclin-dependent kinase 1/cyclin B isolated from oocyte using histone H1 and [gamma33P]ATP as substrate after 30 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article

TargetG2/mitotic-specific cyclin-B1(Rat)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50409922BDBM50409922(CHEMBL2092998)
Affinity DataIC50: 836nMAssay Description:Compound was evaluated for inhibition of rat Nicotinic acetylcholine receptor alpha7 (nAChR) in Xenopus OocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetG2/mitotic-specific cyclin-B2(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50652792BDBM50652792(CHEMBL3752910)
Affinity DataKd:  2.20E+3nMAssay Description:Binding affinity to human CCNB2 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetG2/mitotic-specific cyclin-B1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50652793BDBM50652793(CHEMBL5653589)
Affinity DataKd:  4.30E+3nMAssay Description:Binding affinity to human CCNB1 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetG2/mitotic-specific cyclin-B2(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50652793BDBM50652793(CHEMBL5653589)
Affinity DataKd:  9.44E+3nMAssay Description:Binding affinity to human CCNB2 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetG2/mitotic-specific cyclin-B(Starfish)TBA
LigandChemical structure of BindingDB Monomer ID 50488799BDBM50488799(CHEMBL2295959)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Asteroidea (starfish) Cyclin-dependent kinase 1/cyclin B isolated from oocyte using histone H1 and [gamma33P]ATP as substrate after 30 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article