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Found 11 Enz. Inhib. hit(s) with Target = 'Gamma-aminobutyric acid receptor subunit alpha-5 [32-462]/beta-3 [26-473]/gamma-2 [40-467]'
TargetGamma-aminobutyric acid receptor subunit alpha-5 [32-462]/beta-3 [26-473]/gamma-2 [40-467](Homo sapiens (Human))
University Of Wisconsin-Milwaukee

LigandPNGBDBM25877(CHEMBL286594 | RY-80, 1 | ethyl 12-ethynyl-8-methy...)
Affinity DataKi:  0.490nMAssay Description:The affinity of compounds for human recombinant GABA (A) receptors was measured by competition binding using [3H]flunitrazepam. Assays were carried o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-5 [32-462]/beta-3 [26-473]/gamma-2 [40-467](Homo sapiens (Human))
University Of Wisconsin-Milwaukee

LigandPNGBDBM649937(1-(6-{[3-(4-fluorophenyl)-5-methyl-1,2-oxazol-4-yl...)
Affinity DataKi:  0.900nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetGamma-aminobutyric acid receptor subunit alpha-5 [32-462]/beta-3 [26-473]/gamma-2 [40-467](Homo sapiens (Human))
University Of Wisconsin-Milwaukee

LigandPNGBDBM25880(5-({12-ethynyl-8-methyl-9-oxo-2,4,8-triazatricyclo...)
Affinity DataKi:  5.40nMAssay Description:The affinity of compounds for human recombinant GABA (A) receptors was measured by competition binding using [3H]flunitrazepam. Assays were carried o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-5 [32-462]/beta-3 [26-473]/gamma-2 [40-467](Homo sapiens (Human))
University Of Wisconsin-Milwaukee

LigandPNGBDBM649918(1-(6-{[1-(4-fluorophenyl)-4-methyl-1H-1,2,3-triazo...)
Affinity DataKi:  10nMMore data for this Ligand-Target Pair
Ligand Info
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TargetGamma-aminobutyric acid receptor subunit alpha-5 [32-462]/beta-3 [26-473]/gamma-2 [40-467](Homo sapiens (Human))
University Of Wisconsin-Milwaukee

LigandPNGBDBM25883(ethyl 12-ethynyl-9-phenyl-2,4,8-triazatricyclo[8.4...)
Affinity DataKi:  13.8nMAssay Description:The affinity of compounds for human recombinant GABA (A) receptors was measured by competition binding using [3H]flunitrazepam. Assays were carried o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-5 [32-462]/beta-3 [26-473]/gamma-2 [40-467](Homo sapiens (Human))
University Of Wisconsin-Milwaukee

LigandPNGBDBM25879(3-({12-ethynyl-8-methyl-9-oxo-2,4,8-triazatricyclo...)
Affinity DataKi:  15nMAssay Description:The affinity of compounds for human recombinant GABA (A) receptors was measured by competition binding using [3H]flunitrazepam. Assays were carried o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-5 [32-462]/beta-3 [26-473]/gamma-2 [40-467](Homo sapiens (Human))
University Of Wisconsin-Milwaukee

LigandPNGBDBM649920(1-(6-{[4-(4-fluorophenyl)-1-methyl-1H-1,2,3-triazo...)
Affinity DataKi:  32nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetGamma-aminobutyric acid receptor subunit alpha-5 [32-462]/beta-3 [26-473]/gamma-2 [40-467](Homo sapiens (Human))
University Of Wisconsin-Milwaukee

LigandPNGBDBM25882(XLi374, 5 | [({12-ethynyl-8-methyl-9-oxo-2,4,8-tri...)
Affinity DataKi:  76.1nMAssay Description:The affinity of compounds for human recombinant GABA (A) receptors was measured by competition binding using [3H]flunitrazepam. Assays were carried o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-5 [32-462]/beta-3 [26-473]/gamma-2 [40-467](Homo sapiens (Human))
University Of Wisconsin-Milwaukee

LigandPNGBDBM25881(3-({12-ethyl-8-methyl-9-oxo-2,4,8-triazatricyclo[8...)
Affinity DataKi:  101nMAssay Description:The affinity of compounds for human recombinant GABA (A) receptors was measured by competition binding using [3H]flunitrazepam. Assays were carried o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-5 [32-462]/beta-3 [26-473]/gamma-2 [40-467](Homo sapiens (Human))
University Of Wisconsin-Milwaukee

LigandPNGBDBM25885(3-({12-ethynyl-9-phenyl-2,4,8-triazatricyclo[8.4.0...)
Affinity DataKi:  194nMAssay Description:The affinity of compounds for human recombinant GABA (A) receptors was measured by competition binding using [3H]flunitrazepam. Assays were carried o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-5 [32-462]/beta-3 [26-473]/gamma-2 [40-467](Homo sapiens (Human))
University Of Wisconsin-Milwaukee

LigandPNGBDBM25884(2-[2-({12-ethynyl-9-phenyl-2,4,8-triazatricyclo[8....)
Affinity DataKi:  5.00E+3nMAssay Description:The affinity of compounds for human recombinant GABA (A) receptors was measured by competition binding using [3H]flunitrazepam. Assays were carried o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed