Compile Data Set for Download or QSAR
Report error Found 791 Enz. Inhib. hit(s) with Target = 'GTPase KRas [G12S]'
TargetGTPase KRas [G12S](Human)
Merck Sharp & Dohme LLC

US Patent
LigandChemical structure of BindingDB Monomer ID 785345BDBM785345(US12466840, Example Ex-2)
Affinity DataIC50: 0.690nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/2/2026
Entry Details US Patent

TargetGTPase KRas [G12S](Human)
Merck Sharp & Dohme LLC

US Patent
LigandChemical structure of BindingDB Monomer ID 785347BDBM785347(US12466840, Example Ex-4)
Affinity DataIC50: 0.690nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/2/2026
Entry Details US Patent

TargetGTPase KRas [G12S](Human)
Merck Sharp & Dohme LLC

US Patent
LigandChemical structure of BindingDB Monomer ID 785344BDBM785344(US12466840, Example Ex-1)
Affinity DataIC50: 0.690nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/2/2026
Entry Details US Patent

TargetGTPase KRas [G12S](Human)
Merck Sharp & Dohme LLC

US Patent
LigandChemical structure of BindingDB Monomer ID 785348BDBM785348(US12466840, Example Ex-5)
Affinity DataIC50: 0.770nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/2/2026
Entry Details US Patent

TargetGTPase KRas [G12S](Human)
Merck Sharp & Dohme LLC

US Patent
LigandChemical structure of BindingDB Monomer ID 785349BDBM785349(US12466840, Example Ex-6)
Affinity DataIC50: 1.20nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/2/2026
Entry Details US Patent

TargetGTPase KRas [G12S](Human)
Merck Sharp & Dohme LLC

US Patent
LigandChemical structure of BindingDB Monomer ID 785350BDBM785350(US12466840, Example Ex-7)
Affinity DataIC50: 1.30nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/2/2026
Entry Details US Patent

TargetGTPase KRas [G12S](Human)
Merck Sharp & Dohme LLC

US Patent
LigandChemical structure of BindingDB Monomer ID 592032BDBM592032(US11566007, Example A712)
Affinity DataIC50: 55nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase KRas [G12S](Human)
Merck Sharp & Dohme LLC

US Patent
LigandChemical structure of BindingDB Monomer ID 591654BDBM591654(US11566007, Example A333)
Affinity DataIC50: 55nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase KRas [G12S](Human)
Merck Sharp & Dohme LLC

US Patent
LigandChemical structure of BindingDB Monomer ID 591784BDBM591784(US11566007, Example A464 | US11566007, Example A46...)
Affinity DataIC50: 55nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase KRas [G12S](Human)
Merck Sharp & Dohme LLC

US Patent
LigandChemical structure of BindingDB Monomer ID 591784BDBM591784(US11566007, Example A464 | US11566007, Example A46...)
Affinity DataIC50: 55nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase KRas [G12S](Human)
Merck Sharp & Dohme LLC

US Patent
LigandChemical structure of BindingDB Monomer ID 591655BDBM591655(US11566007, Example A334)
Affinity DataIC50: 55nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase KRas [G12S](Human)
Merck Sharp & Dohme LLC

US Patent
LigandChemical structure of BindingDB Monomer ID 591409BDBM591409(US11566007, Example A87)
Affinity DataIC50: 55nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase KRas [G12S](Human)
Merck Sharp & Dohme LLC

US Patent
LigandChemical structure of BindingDB Monomer ID 591897BDBM591897(US11566007, Example A577)
Affinity DataIC50: 55nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase KRas [G12S](Human)
Merck Sharp & Dohme LLC

US Patent
LigandChemical structure of BindingDB Monomer ID 591640BDBM591640(US11566007, Example A319)
Affinity DataIC50: 55nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase KRas [G12S](Human)
Merck Sharp & Dohme LLC

US Patent
LigandChemical structure of BindingDB Monomer ID 591555BDBM591555(US11566007, Example A233)
Affinity DataIC50: 55nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase KRas [G12S](Human)
Merck Sharp & Dohme LLC

US Patent
LigandChemical structure of BindingDB Monomer ID 591811BDBM591811(US11566007, Example A491 | US11566007, Example A49...)
Affinity DataIC50: 55nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase KRas [G12S](Human)
Merck Sharp & Dohme LLC

US Patent
LigandChemical structure of BindingDB Monomer ID 591941BDBM591941(US11566007, Example A621)
Affinity DataIC50: 55nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase KRas [G12S](Human)
Merck Sharp & Dohme LLC

US Patent
LigandChemical structure of BindingDB Monomer ID 591811BDBM591811(US11566007, Example A491 | US11566007, Example A49...)
Affinity DataIC50: 55nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase KRas [G12S](Human)
Merck Sharp & Dohme LLC

US Patent
LigandChemical structure of BindingDB Monomer ID 591811BDBM591811(US11566007, Example A491 | US11566007, Example A49...)
Affinity DataIC50: 55nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase KRas [G12S](Human)
Merck Sharp & Dohme LLC

US Patent
LigandChemical structure of BindingDB Monomer ID 591350BDBM591350(US11566007, Example A28 | Synthesis of (2S)-N-[(8S...)
Affinity DataIC50: 55nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase KRas [G12S](Human)
Merck Sharp & Dohme LLC

US Patent
LigandChemical structure of BindingDB Monomer ID 591688BDBM591688(US11566007, Example A367)
Affinity DataIC50: 55nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase KRas [G12S](Human)
Merck Sharp & Dohme LLC

US Patent
LigandChemical structure of BindingDB Monomer ID 591918BDBM591918(US11566007, Example A598)
Affinity DataIC50: 55nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase KRas [G12S](Human)
Merck Sharp & Dohme LLC

US Patent
LigandChemical structure of BindingDB Monomer ID 591916BDBM591916(US11566007, Example A596)
Affinity DataIC50: 55nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase KRas [G12S](Human)
Merck Sharp & Dohme LLC

US Patent
LigandChemical structure of BindingDB Monomer ID 591659BDBM591659(US11566007, Example A338)
Affinity DataIC50: 55nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase KRas [G12S](Human)
Merck Sharp & Dohme LLC

US Patent
LigandChemical structure of BindingDB Monomer ID 591922BDBM591922(US11566007, Example A602)
Affinity DataIC50: 55nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase KRas [G12S](Human)
Merck Sharp & Dohme LLC

US Patent
LigandChemical structure of BindingDB Monomer ID 592054BDBM592054(US11566007, Example A734)
Affinity DataIC50: 55nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase KRas [G12S](Human)
Merck Sharp & Dohme LLC

US Patent
LigandChemical structure of BindingDB Monomer ID 591929BDBM591929(US11566007, Example A609)
Affinity DataIC50: 55nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase KRas [G12S](Human)
Merck Sharp & Dohme LLC

US Patent
LigandChemical structure of BindingDB Monomer ID 592056BDBM592056(US11566007, Example A736)
Affinity DataIC50: 55nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase KRas [G12S](Human)
Merck Sharp & Dohme LLC

US Patent
LigandChemical structure of BindingDB Monomer ID 591799BDBM591799(US11566007, Example A479)
Affinity DataIC50: 55nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase KRas [G12S](Human)
Merck Sharp & Dohme LLC

US Patent
LigandChemical structure of BindingDB Monomer ID 591584BDBM591584(US11566007, Example A262)
Affinity DataIC50: 55nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase KRas [G12S](Human)
Merck Sharp & Dohme LLC

US Patent
LigandChemical structure of BindingDB Monomer ID 591710BDBM591710(US11566007, Example A389)
Affinity DataIC50: 55nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase KRas [G12S](Human)
Merck Sharp & Dohme LLC

US Patent
LigandChemical structure of BindingDB Monomer ID 591709BDBM591709(US11566007, Example A388)
Affinity DataIC50: 55nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase KRas [G12S](Human)
Merck Sharp & Dohme LLC

US Patent
LigandChemical structure of BindingDB Monomer ID 591582BDBM591582(US11566007, Example A260)
Affinity DataIC50: 55nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase KRas [G12S](Human)
Merck Sharp & Dohme LLC

US Patent
LigandChemical structure of BindingDB Monomer ID 591588BDBM591588(US11566007, Example A266)
Affinity DataIC50: 55nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase KRas [G12S](Human)
Merck Sharp & Dohme LLC

US Patent
LigandChemical structure of BindingDB Monomer ID 591587BDBM591587(US11566007, Example A265)
Affinity DataIC50: 55nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase KRas [G12S](Human)
Merck Sharp & Dohme LLC

US Patent
LigandChemical structure of BindingDB Monomer ID 591586BDBM591586(US11566007, Example A264)
Affinity DataIC50: 55nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase KRas [G12S](Human)
Merck Sharp & Dohme LLC

US Patent
LigandChemical structure of BindingDB Monomer ID 591592BDBM591592(US11566007, Example A270)
Affinity DataIC50: 55nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase KRas [G12S](Human)
Merck Sharp & Dohme LLC

US Patent
LigandChemical structure of BindingDB Monomer ID 591590BDBM591590(US11566007, Example A268)
Affinity DataIC50: 55nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase KRas [G12S](Human)
Merck Sharp & Dohme LLC

US Patent
LigandChemical structure of BindingDB Monomer ID 591847BDBM591847(US11566007, Example A527)
Affinity DataIC50: 55nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase KRas [G12S](Human)
Merck Sharp & Dohme LLC

US Patent
LigandChemical structure of BindingDB Monomer ID 591949BDBM591949(US11566007, Example A629)
Affinity DataIC50: 55nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase KRas [G12S](Human)
Merck Sharp & Dohme LLC

US Patent
LigandChemical structure of BindingDB Monomer ID 591706BDBM591706(US11566007, Example A385)
Affinity DataIC50: 55nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase KRas [G12S](Human)
Merck Sharp & Dohme LLC

US Patent
LigandChemical structure of BindingDB Monomer ID 591578BDBM591578(US11566007, Example A256)
Affinity DataIC50: 55nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase KRas [G12S](Human)
Merck Sharp & Dohme LLC

US Patent
LigandChemical structure of BindingDB Monomer ID 591704BDBM591704(US11566007, Example A383)
Affinity DataIC50: 55nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase KRas [G12S](Human)
Merck Sharp & Dohme LLC

US Patent
LigandChemical structure of BindingDB Monomer ID 591577BDBM591577(US11566007, Example A255)
Affinity DataIC50: 55nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase KRas [G12S](Human)
Merck Sharp & Dohme LLC

US Patent
LigandChemical structure of BindingDB Monomer ID 591703BDBM591703(US11566007, Example A382)
Affinity DataIC50: 55nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase KRas [G12S](Human)
Merck Sharp & Dohme LLC

US Patent
LigandChemical structure of BindingDB Monomer ID 591614BDBM591614(US11566007, Example A292)
Affinity DataIC50: 55nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase KRas [G12S](Human)
Merck Sharp & Dohme LLC

US Patent
LigandChemical structure of BindingDB Monomer ID 591739BDBM591739(US11566007, Example A418)
Affinity DataIC50: 55nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase KRas [G12S](Human)
Merck Sharp & Dohme LLC

US Patent
LigandChemical structure of BindingDB Monomer ID 591398BDBM591398(US11566007, Example A76 | US11566007, Example A112)
Affinity DataIC50: 55nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase KRas [G12S](Human)
Merck Sharp & Dohme LLC

US Patent
LigandChemical structure of BindingDB Monomer ID 591617BDBM591617(US11566007, Example A295)
Affinity DataIC50: 55nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase KRas [G12S](Human)
Merck Sharp & Dohme LLC

US Patent
LigandChemical structure of BindingDB Monomer ID 591616BDBM591616(US11566007, Example A294)
Affinity DataIC50: 55nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

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