Compile Data Set for Download or QSAR
Report error Found 696 Enz. Inhib. hit(s) with Target = 'GTPase KRas [G13D]'
TargetGTPase KRas [G13D](Human)
Merck Sharp & Dohme LLC

US Patent
LigandChemical structure of BindingDB Monomer ID 785347BDBM785347(US12466840, Example Ex-4)
Affinity DataIC50: 0.890nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/2/2026
Entry Details US Patent

TargetGTPase KRas [G13D](Human)
Merck Sharp & Dohme LLC

US Patent
LigandChemical structure of BindingDB Monomer ID 785345BDBM785345(US12466840, Example Ex-2)
Ligand Info
In Depth
Date in BDB:
3/2/2026
Entry Details US Patent

TargetGTPase KRas [G13D](Human)
Merck Sharp & Dohme LLC

US Patent
LigandChemical structure of BindingDB Monomer ID 785348BDBM785348(US12466840, Example Ex-5)
Affinity DataIC50: 1.20nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/2/2026
Entry Details US Patent

TargetGTPase KRas [G13D](Human)
Merck Sharp & Dohme LLC

US Patent
LigandChemical structure of BindingDB Monomer ID 785349BDBM785349(US12466840, Example Ex-6)
Affinity DataIC50: 1.90nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/2/2026
Entry Details US Patent

TargetGTPase KRas [G13D](Human)
Merck Sharp & Dohme LLC

US Patent
LigandChemical structure of BindingDB Monomer ID 785350BDBM785350(US12466840, Example Ex-7)
Affinity DataIC50: 2.40nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/2/2026
Entry Details US Patent

TargetGTPase KRas [G13D](Human)
Merck Sharp & Dohme LLC

US Patent
LigandChemical structure of BindingDB Monomer ID 785344BDBM785344(US12466840, Example Ex-1)
Affinity DataIC50: 3.70nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/2/2026
Entry Details US Patent

TargetGTPase KRas [G13D]/Son of sevenless homolog 1 [564-1049](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 678346BDBM678346(US20240174690, Example II-195)
Affinity DataIC50: 7nMAssay Description:These assays measure the inhibitory effect of compounds on KRAS mutant protein-protein interactions using the Alpha Screen technology by Perkin Elmer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent

TargetGTPase KRas [G13D]/Son of sevenless homolog 1 [564-1049](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 678343BDBM678343(US20240174690, Example II-192)
Affinity DataIC50: 7nMAssay Description:These assays measure the inhibitory effect of compounds on KRAS mutant protein-protein interactions using the Alpha Screen technology by Perkin Elmer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent

TargetGTPase KRas [G13D]/Son of sevenless homolog 1 [564-1049](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 678193BDBM678193(US20240174690, Example II-26)
Affinity DataIC50: 8nMAssay Description:These assays measure the inhibitory effect of compounds on KRAS mutant protein-protein interactions using the Alpha Screen technology by Perkin Elmer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent

TargetGTPase KRas [G13D]/Son of sevenless homolog 1 [564-1049](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 678335BDBM678335(US20240174690, Example II-182)
Affinity DataIC50: 8nMAssay Description:These assays measure the inhibitory effect of compounds on KRAS mutant protein-protein interactions using the Alpha Screen technology by Perkin Elmer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent

TargetGTPase KRas [G13D]/Son of sevenless homolog 1 [564-1049](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 678242BDBM678242(US20240174690, Example II-77)
Affinity DataIC50: 8nMAssay Description:These assays measure the inhibitory effect of compounds on KRAS mutant protein-protein interactions using the Alpha Screen technology by Perkin Elmer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent

TargetGTPase KRas [G13D]/Son of sevenless homolog 1 [564-1049](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 678197BDBM678197(US20240174690, Example II-31)
Affinity DataIC50: 8nMAssay Description:These assays measure the inhibitory effect of compounds on KRAS mutant protein-protein interactions using the Alpha Screen technology by Perkin Elmer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent

TargetGTPase KRas [G13D]/Son of sevenless homolog 1 [564-1049](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 678181BDBM678181(US20240174690, Example II-13)
Affinity DataIC50: 8nMAssay Description:These assays measure the inhibitory effect of compounds on KRAS mutant protein-protein interactions using the Alpha Screen technology by Perkin Elmer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent

TargetGTPase KRas [G13D]/Son of sevenless homolog 1 [564-1049](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 678237BDBM678237(US20240174690, Example II-72)
Affinity DataIC50: 9nMAssay Description:These assays measure the inhibitory effect of compounds on KRAS mutant protein-protein interactions using the Alpha Screen technology by Perkin Elmer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent

TargetGTPase KRas [G13D]/Son of sevenless homolog 1 [564-1049](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 678187BDBM678187(US20240174690, Example II-19)
Affinity DataIC50: 9nMAssay Description:These assays measure the inhibitory effect of compounds on KRAS mutant protein-protein interactions using the Alpha Screen technology by Perkin Elmer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent

TargetGTPase KRas [G13D]/Son of sevenless homolog 1 [564-1049](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 678259BDBM678259(US20240174690, Example II-94)
Affinity DataIC50: 9nMAssay Description:These assays measure the inhibitory effect of compounds on KRAS mutant protein-protein interactions using the Alpha Screen technology by Perkin Elmer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent

TargetGTPase KRas [G13D]/Son of sevenless homolog 1 [564-1049](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 678344BDBM678344(US20240174690, Example II-193 | US20240174690, Exa...)
Affinity DataIC50: 9nMAssay Description:These assays measure the inhibitory effect of compounds on KRAS mutant protein-protein interactions using the Alpha Screen technology by Perkin Elmer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent

TargetGTPase KRas [G13D]/Son of sevenless homolog 1 [564-1049](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 678192BDBM678192(US20240174690, Example II-25)
Affinity DataIC50: 11nMAssay Description:These assays measure the inhibitory effect of compounds on KRAS mutant protein-protein interactions using the Alpha Screen technology by Perkin Elmer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent

TargetGTPase KRas [G13D]/Son of sevenless homolog 1 [564-1049](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 678189BDBM678189(US20240174690, Example II-21)
Affinity DataIC50: 12nMAssay Description:These assays measure the inhibitory effect of compounds on KRAS mutant protein-protein interactions using the Alpha Screen technology by Perkin Elmer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent

TargetGTPase KRas [G13D]/Son of sevenless homolog 1 [564-1049](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 678280BDBM678280(US20240174690, Example II-116)
Affinity DataIC50: 17nMAssay Description:These assays measure the inhibitory effect of compounds on KRAS mutant protein-protein interactions using the Alpha Screen technology by Perkin Elmer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent

TargetGTPase KRas [G13D]/Son of sevenless homolog 1 [564-1049](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 678235BDBM678235(US20240174690, Example II-70)
Affinity DataIC50: 19nMAssay Description:These assays measure the inhibitory effect of compounds on KRAS mutant protein-protein interactions using the Alpha Screen technology by Perkin Elmer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent

TargetGTPase KRas [G13D]/Son of sevenless homolog 1 [564-1049](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 678112BDBM678112(US20240174690, Example I-4)
Affinity DataIC50: 20nMAssay Description:These assays measure the inhibitory effect of compounds on KRAS mutant protein-protein interactions using the Alpha Screen technology by Perkin Elmer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent

TargetGTPase KRas [G13D]/Son of sevenless homolog 1 [564-1049](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 678352BDBM678352(US20240174690, Example II-201)
Affinity DataIC50: 27nMAssay Description:These assays measure the inhibitory effect of compounds on KRAS mutant protein-protein interactions using the Alpha Screen technology by Perkin Elmer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent

TargetGTPase KRas [G13D]/Son of sevenless homolog 1 [564-1049](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 678219BDBM678219(US20240174690, Example II-54)
Affinity DataIC50: 33nMAssay Description:These assays measure the inhibitory effect of compounds on KRAS mutant protein-protein interactions using the Alpha Screen technology by Perkin Elmer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent

TargetGTPase KRas [G13D]/Son of sevenless homolog 1 [564-1049](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 678200BDBM678200(US20240174690, Example II-34)
Affinity DataIC50: 38nMAssay Description:These assays measure the inhibitory effect of compounds on KRAS mutant protein-protein interactions using the Alpha Screen technology by Perkin Elmer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent

TargetGTPase KRas [G13D]/Son of sevenless homolog 1 [564-1049](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 678241BDBM678241(US20240174690, Example II-76)
Affinity DataIC50: 41nMAssay Description:These assays measure the inhibitory effect of compounds on KRAS mutant protein-protein interactions using the Alpha Screen technology by Perkin Elmer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent

TargetGTPase KRas [G13D]/Son of sevenless homolog 1 [564-1049](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 678220BDBM678220(US20240174690, Example II-55)
Affinity DataIC50: 47nMAssay Description:These assays measure the inhibitory effect of compounds on KRAS mutant protein-protein interactions using the Alpha Screen technology by Perkin Elmer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent

TargetGTPase KRas [G13D]/Son of sevenless homolog 1 [564-1049](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 678321BDBM678321(US20240174690, Example II-165 | US20240174690, Exa...)
Affinity DataIC50: 48nMAssay Description:These assays measure the inhibitory effect of compounds on KRAS mutant protein-protein interactions using the Alpha Screen technology by Perkin Elmer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent

TargetGTPase KRas [G13D](Human)
Merck Sharp & Dohme LLC

US Patent
LigandChemical structure of BindingDB Monomer ID 591640BDBM591640(US11566007, Example A319)
Affinity DataIC50: 55nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase KRas [G13D](Human)
Merck Sharp & Dohme LLC

US Patent
LigandChemical structure of BindingDB Monomer ID 591862BDBM591862(US11566007, Example A542 | The synthesis of 1-(4-(...)
Affinity DataIC50: 55nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase KRas [G13D](Human)
Merck Sharp & Dohme LLC

US Patent
LigandChemical structure of BindingDB Monomer ID 591582BDBM591582(US11566007, Example A260)
Affinity DataIC50: 55nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase KRas [G13D](Human)
Merck Sharp & Dohme LLC

US Patent
LigandChemical structure of BindingDB Monomer ID 591585BDBM591585(US11566007, Example A263)
Affinity DataIC50: 55nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase KRas [G13D](Human)
Merck Sharp & Dohme LLC

US Patent
LigandChemical structure of BindingDB Monomer ID 591584BDBM591584(US11566007, Example A262)
Affinity DataIC50: 55nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase KRas [G13D](Human)
Merck Sharp & Dohme LLC

US Patent
LigandChemical structure of BindingDB Monomer ID 591616BDBM591616(US11566007, Example A294)
Affinity DataIC50: 55nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase KRas [G13D](Human)
Merck Sharp & Dohme LLC

US Patent
LigandChemical structure of BindingDB Monomer ID 591709BDBM591709(US11566007, Example A388)
Affinity DataIC50: 55nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase KRas [G13D](Human)
Merck Sharp & Dohme LLC

US Patent
LigandChemical structure of BindingDB Monomer ID 591589BDBM591589(US11566007, Example A267)
Affinity DataIC50: 55nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase KRas [G13D](Human)
Merck Sharp & Dohme LLC

US Patent
LigandChemical structure of BindingDB Monomer ID 591620BDBM591620(US11566007, Example A298)
Affinity DataIC50: 55nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase KRas [G13D](Human)
Merck Sharp & Dohme LLC

US Patent
LigandChemical structure of BindingDB Monomer ID 591587BDBM591587(US11566007, Example A265)
Affinity DataIC50: 55nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase KRas [G13D](Human)
Merck Sharp & Dohme LLC

US Patent
LigandChemical structure of BindingDB Monomer ID 591586BDBM591586(US11566007, Example A264)
Affinity DataIC50: 55nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase KRas [G13D](Human)
Merck Sharp & Dohme LLC

US Patent
LigandChemical structure of BindingDB Monomer ID 591618BDBM591618(US11566007, Example A296)
Affinity DataIC50: 55nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase KRas [G13D](Human)
Merck Sharp & Dohme LLC

US Patent
LigandChemical structure of BindingDB Monomer ID 591784BDBM591784(US11566007, Example A464 | US11566007, Example A46...)
Affinity DataIC50: 55nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase KRas [G13D](Human)
Merck Sharp & Dohme LLC

US Patent
LigandChemical structure of BindingDB Monomer ID 591847BDBM591847(US11566007, Example A527)
Affinity DataIC50: 55nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase KRas [G13D](Human)
Merck Sharp & Dohme LLC

US Patent
LigandChemical structure of BindingDB Monomer ID 591592BDBM591592(US11566007, Example A270)
Affinity DataIC50: 55nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase KRas [G13D](Human)
Merck Sharp & Dohme LLC

US Patent
LigandChemical structure of BindingDB Monomer ID 591654BDBM591654(US11566007, Example A333)
Affinity DataIC50: 55nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase KRas [G13D](Human)
Merck Sharp & Dohme LLC

US Patent
LigandChemical structure of BindingDB Monomer ID 591590BDBM591590(US11566007, Example A268)
Affinity DataIC50: 55nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase KRas [G13D](Human)
Merck Sharp & Dohme LLC

US Patent
LigandChemical structure of BindingDB Monomer ID 591622BDBM591622(US11566007, Example A300)
Affinity DataIC50: 55nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase KRas [G13D](Human)
Merck Sharp & Dohme LLC

US Patent
LigandChemical structure of BindingDB Monomer ID 591659BDBM591659(US11566007, Example A338)
Affinity DataIC50: 55nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase KRas [G13D](Human)
Merck Sharp & Dohme LLC

US Patent
LigandChemical structure of BindingDB Monomer ID 591784BDBM591784(US11566007, Example A464 | US11566007, Example A46...)
Affinity DataIC50: 55nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase KRas [G13D](Human)
Merck Sharp & Dohme LLC

US Patent
LigandChemical structure of BindingDB Monomer ID 591984BDBM591984(US11566007, Example A664)
Affinity DataIC50: 55nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase KRas [G13D](Human)
Merck Sharp & Dohme LLC

US Patent
LigandChemical structure of BindingDB Monomer ID 591398BDBM591398(US11566007, Example A76 | US11566007, Example A112)
Affinity DataIC50: 55nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

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