Compile Data Set for Download or QSAR
Report error Found 1280 Enz. Inhib. hit(s) with Target = 'GTPase NRas [G12C]'
TargetGTPase NRas [G12C](Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 592031BDBM592031(US11566007, Example A711)
Affinity DataIC50: 10nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase NRas [G12C](Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 592041BDBM592041(US11566007, Example A721)
Affinity DataIC50: 10nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase NRas [G12C](Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 592019BDBM592019(US11566007, Example A699)
Affinity DataIC50: 10nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase NRas [G12C](Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 592027BDBM592027(US11566007, Example A707)
Affinity DataIC50: 10nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase NRas [G12C](Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 592025BDBM592025(US11566007, Example A705)
Affinity DataIC50: 10nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase NRas [G12C](Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 751132BDBM751132(US20250195521, Example A577)
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

TargetGTPase NRas [G12C](Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 591568BDBM591568(US11566007, Example A246)
Affinity DataIC50: 10nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase NRas [G12C](Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 591567BDBM591567(US11566007, Example A245)
Affinity DataIC50: 10nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase NRas [G12C](Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 591566BDBM591566(US11566007, Example A244)
Affinity DataIC50: 10nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase NRas [G12C](Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 591569BDBM591569(US11566007, Example A247)
Affinity DataIC50: 10nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase NRas [G12C](Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 592047BDBM592047(US11566007, Example A727)
Affinity DataIC50: 10nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase NRas [G12C](Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 591794BDBM591794(US11566007, Example A474 | US11566007, Example A47...)
Affinity DataIC50: 10nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase NRas [G12C](Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 591794BDBM591794(US11566007, Example A474 | US11566007, Example A47...)
Affinity DataIC50: 10nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase NRas [G12C](Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 591799BDBM591799(US11566007, Example A479)
Affinity DataIC50: 10nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase NRas [G12C](Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 592055BDBM592055(US11566007, Example A735 | Synthesis of 2-acryloyl...)
Affinity DataIC50: 10nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase NRas [G12C](Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 750855BDBM750855(US20250195521, Example A325)
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

TargetGTPase NRas [G12C](Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 750853BDBM750853(US20250195521, Example A323)
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

TargetGTPase NRas [G12C](Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 591590BDBM591590(US11566007, Example A268)
Affinity DataIC50: 10nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase NRas [G12C](Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 591588BDBM591588(US11566007, Example A266)
Affinity DataIC50: 10nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase NRas [G12C](Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 751151BDBM751151(US20250195521, Example A594)
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

TargetGTPase NRas [G12C](Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 591592BDBM591592(US11566007, Example A270)
Affinity DataIC50: 10nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase NRas [G12C](Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 591847BDBM591847(US11566007, Example A527)
Affinity DataIC50: 10nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase NRas [G12C](Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 591849BDBM591849(US11566007, Example A529)
Affinity DataIC50: 10nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase NRas [G12C](Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 591579BDBM591579(US11566007, Example A257)
Affinity DataIC50: 10nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase NRas [G12C](Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 591577BDBM591577(US11566007, Example A255)
Affinity DataIC50: 10nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase NRas [G12C](Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 751133BDBM751133(US20250195521, Example A578)
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

TargetGTPase NRas [G12C](Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 591829BDBM591829(US11566007, Example A509)
Affinity DataIC50: 10nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase NRas [G12C](Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 591871BDBM591871(US11566007, Example A551)
Affinity DataIC50: 10nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase NRas [G12C](Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 591616BDBM591616(US11566007, Example A294)
Affinity DataIC50: 10nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase NRas [G12C](Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 591870BDBM591870(US11566007, Example A550)
Affinity DataIC50: 10nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase NRas [G12C](Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 591622BDBM591622(US11566007, Example A300)
Affinity DataIC50: 10nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase NRas [G12C](Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 591876BDBM591876(US11566007, Example A556)
Affinity DataIC50: 10nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase NRas [G12C](Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 591621BDBM591621(US11566007, Example A299)
Affinity DataIC50: 10nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase NRas [G12C](Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 591620BDBM591620(US11566007, Example A298)
Affinity DataIC50: 10nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase NRas [G12C](Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 591619BDBM591619(US11566007, Example A297)
Affinity DataIC50: 10nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase NRas [G12C](Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 591854BDBM591854(US11566007, Example A534 | (2S)-2-((S)-7-(4-(dimet...)
Affinity DataIC50: 10nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase NRas [G12C](Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 591856BDBM591856(US11566007, Example A536 | US11566007, Example A53...)
Affinity DataIC50: 10nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase NRas [G12C](Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 591864BDBM591864(US11566007, Example A544)
Affinity DataIC50: 10nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase NRas [G12C](Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 591863BDBM591863(US11566007, Example A543)
Affinity DataIC50: 10nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase NRas [G12C](Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 591862BDBM591862(US11566007, Example A542 | The synthesis of 1-(4-(...)
Affinity DataIC50: 10nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase NRas [G12C](Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 591614BDBM591614(US11566007, Example A292)
Affinity DataIC50: 10nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase NRas [G12C](Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 591612BDBM591612(US11566007, Example A290)
Affinity DataIC50: 10nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase NRas [G12C](Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 591417BDBM591417(US11566007, Example A95 | Synthesis of (2S)-N-[(8S...)
Affinity DataIC50: 10nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase NRas [G12C](Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 591410BDBM591410(US11566007, Example A88)
Affinity DataIC50: 10nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase NRas [G12C](Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 591398BDBM591398(US11566007, Example A76 | US11566007, Example A112)
Affinity DataIC50: 10nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase NRas [G12C](Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 591647BDBM591647(US11566007, Example A326)
Affinity DataIC50: 10nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase NRas [G12C](Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 591418BDBM591418(US11566007, Example A96)
Affinity DataIC50: 10nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase NRas [G12C](Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 591430BDBM591430(US11566007, Example A108)
Affinity DataIC50: 10nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase NRas [G12C](Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 591429BDBM591429(US11566007, Example A107)
Affinity DataIC50: 10nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetGTPase NRas [G12C](Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 591911BDBM591911(US11566007, Example A591)
Affinity DataIC50: 10nMAssay Description:A variety of Ras proteins may be inhibited by compounds of the present invention (e.g., K-Ras, N-Ras, H-Ras, and mutants thereof at positions 12, 13 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

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