Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with Target = 'Gag-Pol polyprotein [600-1028,C879S]/[600-1151,C879S]'
TargetGag-Pol polyprotein [600-1028,C879S]/[600-1151,C879S](Human immunodeficiency virus type 1)
Rutgers University

LigandChemical structure of BindingDB Monomer ID 33960BDBM33960(dihydroxy benzoyl naphthyl hydrazone (DHBNH) analo...)
Affinity DataIC50: 400nMpH: 7.8 T: 2°CAssay Description:HIV-1 RT RDDP activity was generally determined by a fixed time assay. Briefly, reaction mixtures contained p51/p66 RT, template-primer, and [3H]-TTP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [600-1028,C879S]/[600-1151,C879S](Human immunodeficiency virus type 1)
Rutgers University

LigandChemical structure of BindingDB Monomer ID 33959BDBM33959(dihydroxy benzoyl naphthyl hydrazone (DHBNH) analo...)
Affinity DataIC50: 500nMpH: 7.8 T: 2°CAssay Description:HIV-1 RT RDDP activity was generally determined by a fixed time assay. Briefly, reaction mixtures contained p51/p66 RT, template-primer, and [3H]-TTP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [600-1028,C879S]/[600-1151,C879S](Human immunodeficiency virus type 1)
Rutgers University

LigandChemical structure of BindingDB Monomer ID 33953BDBM33953(dihydroxy benzoyl naphthyl hydrazone (DHBNH))
Affinity DataIC50: 500nMpH: 8.0 T: 2°CAssay Description:To assess the effect of inhibitors, RT RNH activity was measured using a FRET-based microplate fluorescence assay. Briefly, the RNA-DNA hybrid duplex...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGag-Pol polyprotein [600-1028,C879S]/[600-1151,C879S](Human immunodeficiency virus type 1)
Rutgers University

LigandChemical structure of BindingDB Monomer ID 33961BDBM33961(dihydroxy benzoyl naphthyl hydrazone (DHBNH) analo...)
Affinity DataIC50: 1.00E+3nMpH: 7.8 T: 2°CAssay Description:HIV-1 RT RDDP activity was generally determined by a fixed time assay. Briefly, reaction mixtures contained p51/p66 RT, template-primer, and [3H]-TTP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [600-1028,C879S]/[600-1151,C879S](Human immunodeficiency virus type 1)
Rutgers University

LigandChemical structure of BindingDB Monomer ID 33957BDBM33957(dihydroxy benzoyl naphthyl hydrazone (DHBNH) analo...)
Affinity DataIC50: 2.00E+3nMpH: 8.0 T: 2°CAssay Description:To assess the effect of inhibitors, RT RNH activity was measured using a FRET-based microplate fluorescence assay. Briefly, the RNA-DNA hybrid duplex...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [600-1028,C879S]/[600-1151,C879S](Human immunodeficiency virus type 1)
Rutgers University

LigandChemical structure of BindingDB Monomer ID 33958BDBM33958(dihydroxy benzoyl naphthyl hydrazone (DHBNH) analo...)
Affinity DataIC50: 2.00E+3nMpH: 7.8 T: 2°CAssay Description:HIV-1 RT RDDP activity was generally determined by a fixed time assay. Briefly, reaction mixtures contained p51/p66 RT, template-primer, and [3H]-TTP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [600-1028,C879S]/[600-1151,C879S](Human immunodeficiency virus type 1)
Rutgers University

LigandChemical structure of BindingDB Monomer ID 33958BDBM33958(dihydroxy benzoyl naphthyl hydrazone (DHBNH) analo...)
Affinity DataIC50: 3.00E+3nMpH: 8.0 T: 2°CAssay Description:To assess the effect of inhibitors, RT RNH activity was measured using a FRET-based microplate fluorescence assay. Briefly, the RNA-DNA hybrid duplex...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [600-1028,C879S]/[600-1151,C879S](Human immunodeficiency virus type 1)
Rutgers University

LigandChemical structure of BindingDB Monomer ID 33959BDBM33959(dihydroxy benzoyl naphthyl hydrazone (DHBNH) analo...)
Affinity DataIC50: 5.00E+3nMpH: 8.0 T: 2°CAssay Description:To assess the effect of inhibitors, RT RNH activity was measured using a FRET-based microplate fluorescence assay. Briefly, the RNA-DNA hybrid duplex...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [600-1028,C879S]/[600-1151,C879S](Human immunodeficiency virus type 1)
Rutgers University

LigandChemical structure of BindingDB Monomer ID 33960BDBM33960(dihydroxy benzoyl naphthyl hydrazone (DHBNH) analo...)
Affinity DataIC50: 7.00E+3nMpH: 8.0 T: 2°CAssay Description:To assess the effect of inhibitors, RT RNH activity was measured using a FRET-based microplate fluorescence assay. Briefly, the RNA-DNA hybrid duplex...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [600-1028,C879S]/[600-1151,C879S](Human immunodeficiency virus type 1)
Rutgers University

LigandChemical structure of BindingDB Monomer ID 33961BDBM33961(dihydroxy benzoyl naphthyl hydrazone (DHBNH) analo...)
Affinity DataIC50: 7.50E+3nMpH: 8.0 T: 2°CAssay Description:To assess the effect of inhibitors, RT RNH activity was measured using a FRET-based microplate fluorescence assay. Briefly, the RNA-DNA hybrid duplex...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [600-1028,C879S]/[600-1151,C879S](Human immunodeficiency virus type 1)
Rutgers University

LigandChemical structure of BindingDB Monomer ID 33956BDBM33956(dihydroxy benzoyl naphthyl hydrazone (DHBNH) analo...)
Affinity DataIC50: 1.20E+4nMpH: 8.0 T: 2°CAssay Description:To assess the effect of inhibitors, RT RNH activity was measured using a FRET-based microplate fluorescence assay. Briefly, the RNA-DNA hybrid duplex...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [600-1028,C879S]/[600-1151,C879S](Human immunodeficiency virus type 1)
Rutgers University

LigandChemical structure of BindingDB Monomer ID 33954BDBM33954(dihydroxy benzoyl naphthyl hydrazone (DHBNH) analo...)
Affinity DataIC50: 1.50E+4nMpH: 8.0 T: 2°CAssay Description:To assess the effect of inhibitors, RT RNH activity was measured using a FRET-based microplate fluorescence assay. Briefly, the RNA-DNA hybrid duplex...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [600-1028,C879S]/[600-1151,C879S](Human immunodeficiency virus type 1)
Rutgers University

LigandChemical structure of BindingDB Monomer ID 33955BDBM33955(dihydroxy benzoyl naphthyl hydrazone (DHBNH) analo...)
Affinity DataIC50: 1.50E+4nMpH: 8.0 T: 2°CAssay Description:To assess the effect of inhibitors, RT RNH activity was measured using a FRET-based microplate fluorescence assay. Briefly, the RNA-DNA hybrid duplex...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [600-1028,C879S]/[600-1151,C879S](Human immunodeficiency virus type 1)
Rutgers University

LigandChemical structure of BindingDB Monomer ID 33953BDBM33953(dihydroxy benzoyl naphthyl hydrazone (DHBNH))
Affinity DataIC50: 2.50E+4nMpH: 7.8 T: 2°CAssay Description:HIV-1 RT RDDP activity was generally determined by a fixed time assay. Briefly, reaction mixtures contained p51/p66 RT, template-primer, and [3H]-TTP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGag-Pol polyprotein [600-1028,C879S]/[600-1151,C879S](Human immunodeficiency virus type 1)
Rutgers University

LigandChemical structure of BindingDB Monomer ID 33954BDBM33954(dihydroxy benzoyl naphthyl hydrazone (DHBNH) analo...)
Affinity DataIC50: 5.00E+4nMpH: 7.8 T: 2°CAssay Description:HIV-1 RT RDDP activity was generally determined by a fixed time assay. Briefly, reaction mixtures contained p51/p66 RT, template-primer, and [3H]-TTP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [600-1028,C879S]/[600-1151,C879S](Human immunodeficiency virus type 1)
Rutgers University

LigandChemical structure of BindingDB Monomer ID 33955BDBM33955(dihydroxy benzoyl naphthyl hydrazone (DHBNH) analo...)
Affinity DataIC50: 5.00E+4nMpH: 7.8 T: 2°CAssay Description:HIV-1 RT RDDP activity was generally determined by a fixed time assay. Briefly, reaction mixtures contained p51/p66 RT, template-primer, and [3H]-TTP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [600-1028,C879S]/[600-1151,C879S](Human immunodeficiency virus type 1)
Rutgers University

LigandChemical structure of BindingDB Monomer ID 33956BDBM33956(dihydroxy benzoyl naphthyl hydrazone (DHBNH) analo...)
Affinity DataIC50: 5.00E+4nMpH: 7.8 T: 2°CAssay Description:HIV-1 RT RDDP activity was generally determined by a fixed time assay. Briefly, reaction mixtures contained p51/p66 RT, template-primer, and [3H]-TTP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [600-1028,C879S]/[600-1151,C879S](Human immunodeficiency virus type 1)
Rutgers University

LigandChemical structure of BindingDB Monomer ID 33957BDBM33957(dihydroxy benzoyl naphthyl hydrazone (DHBNH) analo...)
Affinity DataIC50: 5.00E+4nMpH: 7.8 T: 2°CAssay Description:HIV-1 RT RDDP activity was generally determined by a fixed time assay. Briefly, reaction mixtures contained p51/p66 RT, template-primer, and [3H]-TTP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed