Compile Data Set for Download or QSAR
Report error Found 1830 Enz. Inhib. hit(s) with Target = 'Galectin-1'
TargetGalectin-1(Human)
Galecto Biotech

US Patent
LigandPNGBDBM653575(3,3′-Dideoxy-3-[4-(3,4,5-trifluorophenyl)-1H...)
Affinity DataKd:  3nMAssay Description:The affinity of Example 1-14 for galectins were determined by a fluorescence anisotropy assay where the compound was used as an inhibitor of the inte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2024
Entry Details
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TargetGalectin-1(Human)
Galecto Biotech

US Patent
LigandPNGBDBM653576(US20240059728, Example 2 | 3-[4-(4-Chloro-3,5-difl...)
Affinity DataKd:  4nMAssay Description:The affinity of Example 1-14 for galectins were determined by a fluorescence anisotropy assay where the compound was used as an inhibitor of the inte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2024
Entry Details
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TargetGalectin-1(Human)
Galecto Biotech

US Patent
LigandPNGBDBM50635335(CHEMBL5512479)
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetGalectin-1(Human)
Galecto Biotech

US Patent
LigandPNGBDBM508740(US11046725, Example 16 | 5-Chloro-2-cyano-3-pyridy...)
Affinity DataKd:  6nMAssay Description:The affinity of Example 1-33 for galectins were determined by a fluorescence anisotropy assay where the compound was used as an inhibitor of the inte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2021
Entry Details
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TargetGalectin-1(Human)
Galecto Biotech

US Patent
LigandPNGBDBM653577(US20240059728, Example 3 | 3′-[4-(2-Aminothi...)
Affinity DataKd:  9nMAssay Description:The affinity of Example 1-14 for galectins were determined by a fluorescence anisotropy assay where the compound was used as an inhibitor of the inte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2024
Entry Details
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TargetGalectin-1(Human)
Galecto Biotech

US Patent
LigandPNGBDBM50625734(CHEMBL5417808)
Affinity DataKd: <10nMAssay Description:Binding affinity to galectin-1 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetGalectin-1(Human)
Galecto Biotech

US Patent
LigandPNGBDBM50247477(CHEMBL4102995)
Affinity DataKd: <10nMAssay Description:Displacement of 3,3'-dideoxy-3-[4-(fluorescein-5-yl-carbonylaminomethyl)-1H-1,2,3-triazol-1-yl]-3'-(3,5-dimethoxy-benzamido)-1,1'-sulfanediyl-di-beta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2019
Entry Details Article
PubMed
TargetGalectin-1(Human)
Galecto Biotech

US Patent
LigandPNGBDBM50581762(OLITIGALTIN | Olitigaltin | Td 139 | Td-139 | Td13...)
Affinity DataKd:  12nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetGalectin-1(Human)
Galecto Biotech

US Patent
LigandPNGBDBM50581762(OLITIGALTIN | Olitigaltin | Td 139 | Td-139 | Td13...)
Affinity DataKd:  12nMAssay Description:Binding affinity to galectin-1 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetGalectin-1(Human)
Galecto Biotech

US Patent
LigandPNGBDBM50247476(CHEMBL4091143)
Affinity DataKd:  12nMAssay Description:Displacement of 3,3'-dideoxy-3-[4-(fluorescein-5-yl-carbonylaminomethyl)-1H-1,2,3-triazol-1-yl]-3'-(3,5-dimethoxy-benzamido)-1,1'-sulfanediyl-di-beta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2019
Entry Details Article
PubMed
TargetGalectin-1(Human)
Galecto Biotech

US Patent
LigandPNGBDBM50581762(OLITIGALTIN | Olitigaltin | Td 139 | Td-139 | Td13...)
Affinity DataKd:  12nMAssay Description:Binding affinity to human Gal-1 expressed in Escherichia coli BL21star (DE3) by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetGalectin-1(Human)
Galecto Biotech

US Patent
LigandPNGBDBM508751(US11046725, Example 31 | 3,4-Dichloro-6-fluoro-phe...)
Affinity DataKd:  13nMAssay Description:The affinity of Example 1-33 for galectins were determined by a fluorescence anisotropy assay where the compound was used as an inhibitor of the inte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2021
Entry Details
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TargetGalectin-1(Human)
Galecto Biotech

US Patent
LigandPNGBDBM50425519(CHEMBL2313626)
Affinity DataKd:  13nMAssay Description:Binding affinity to galectin-1 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetGalectin-1(Human)
Galecto Biotech

US Patent
LigandPNGBDBM508739(US11046725, Example 15 | 5-Bromo-6-cyano-3-pyridyl...)
Affinity DataKd:  19nMAssay Description:The affinity of Example 1-33 for galectins were determined by a fluorescence anisotropy assay where the compound was used as an inhibitor of the inte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2021
Entry Details
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TargetGalectin-1(Human)
Galecto Biotech

US Patent
LigandPNGBDBM50635334(CHEMBL5505811)
Affinity DataKd:  20nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetGalectin-1(Human)
Galecto Biotech

US Patent
LigandPNGBDBM508742(US11046725, Example 18 | 3,5-Dichloro-4-fluoro-phe...)
Affinity DataKd:  27nMAssay Description:The affinity of Example 1-33 for galectins were determined by a fluorescence anisotropy assay where the compound was used as an inhibitor of the inte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2021
Entry Details
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TargetGalectin-1(Human)
Galecto Biotech

US Patent
LigandPNGBDBM50247482(CHEMBL4065371)
Affinity DataKd:  27nMAssay Description:Displacement of 3,3'-dideoxy-3-[4-(fluorescein-5-yl-carbonylaminomethyl)-1H-1,2,3-triazol-1-yl]-3'-(3,5-dimethoxy-benzamido)-1,1'-sulfanediyl-di-beta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2019
Entry Details Article
PubMed
TargetGalectin-1(Human)
Galecto Biotech

US Patent
LigandPNGBDBM508741(US11046725, Example 17 | 5-Chloro-6-trifluoromethy...)
Affinity DataKd:  28nMAssay Description:The affinity of Example 1-33 for galectins were determined by a fluorescence anisotropy assay where the compound was used as an inhibitor of the inte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2021
Entry Details
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TargetGalectin-1(Mus musculus)
Galecto Biotech AB

Curated by ChEMBL
LigandPNGBDBM50635334(CHEMBL5505811)
Affinity DataKd:  29nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetGalectin-1(Human)
Galecto Biotech

US Patent
LigandPNGBDBM455403(3,3′-Dideoxy-3-[4-(piperidin-4-yl)-1H-1,2,3-...)
Affinity DataKd:  29nMAssay Description:The affinity of Example 1-5 for galectins were determined by a fluorescence anisotropy assay where the compound was used as an inhibitor of the inter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2021
Entry Details
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TargetGalectin-1(Human)
Galecto Biotech

US Patent
LigandPNGBDBM667997(US20240124427, Example 113 | (2R,3R,4S,5R,6R)-N-(3...)
Affinity DataIC50: 31nMAssay Description:The inhibitory activity of compounds is determined in competitive binding assays. This spectrophotometric assay measures the binding of biotinylated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
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TargetGalectin-1(Human)
Galecto Biotech

US Patent
LigandPNGBDBM508746(US11046725, Example 23 | 5-Bromo-6-trifluoromethyl...)
Affinity DataKd:  32nMAssay Description:The affinity of Example 1-33 for galectins were determined by a fluorescence anisotropy assay where the compound was used as an inhibitor of the inte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2021
Entry Details
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TargetGalectin-1(Human)
Galecto Biotech

US Patent
LigandPNGBDBM508738(US11046725, Example 14 | 5-Bromo-2-cyano-pyridine-...)
Affinity DataKd:  33nMAssay Description:The affinity of Example 1-33 for galectins were determined by a fluorescence anisotropy assay where the compound was used as an inhibitor of the inte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2021
Entry Details
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TargetGalectin-1(Human)
Galecto Biotech

US Patent
LigandPNGBDBM50635329(CHEMBL5556899)
Affinity DataKd:  34nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetGalectin-1(Human)
Galecto Biotech

US Patent
LigandPNGBDBM455402(3,3′-Dideoxy-3-[4-(4-methylpiperazin-1-yl)-1...)
Affinity DataKd:  35nMAssay Description:The affinity of Example 1-5 for galectins were determined by a fluorescence anisotropy assay where the compound was used as an inhibitor of the inter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2021
Entry Details
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TargetGalectin-1(Human)
Galecto Biotech

US Patent
LigandPNGBDBM508737(US11046725, Example 13 | 5-Chloro-6-cyano-pyridine...)
Affinity DataKd:  38nMAssay Description:The affinity of Example 1-33 for galectins were determined by a fluorescence anisotropy assay where the compound was used as an inhibitor of the inte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2021
Entry Details
Go to US Patent

TargetGalectin-1(Human)
Galecto Biotech

US Patent
LigandPNGBDBM667998(US20240124427, Example 114 | (2R,3R,4S,5R,6R)-N-(3...)
Affinity DataIC50: 40nMAssay Description:The inhibitory activity of compounds is determined in competitive binding assays. This spectrophotometric assay measures the binding of biotinylated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
Go to US Patent

TargetGalectin-1(Mus musculus)
Galecto Biotech AB

Curated by ChEMBL
LigandPNGBDBM50635329(CHEMBL5556899)
Affinity DataKd:  43nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetGalectin-1(Human)
Galecto Biotech

US Patent
LigandPNGBDBM508752(US11046725, Example 32 | 4-Chloro-N,N′-dimet...)
Affinity DataKd:  44nMAssay Description:The affinity of Example 1-33 for galectins were determined by a fluorescence anisotropy assay where the compound was used as an inhibitor of the inte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2021
Entry Details
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TargetGalectin-1(Human)
Galecto Biotech

US Patent
LigandPNGBDBM508749(US11046725, Example 28 | 2-carboxy-5-chloropyridyl...)
Affinity DataKd:  46nMAssay Description:The affinity of Example 1-33 for galectins were determined by a fluorescence anisotropy assay where the compound was used as an inhibitor of the inte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2021
Entry Details
Go to US Patent

TargetGalectin-1(Human)
Galecto Biotech

US Patent
LigandPNGBDBM50425520(CHEMBL2313627)
Affinity DataKd:  49nMAssay Description:Binding affinity to galectin-1 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetGalectin-1(Human)
Galecto Biotech

US Patent
LigandPNGBDBM667993(US20240124427, Example 109 | (2R,3R,4S,5R,6R)-N-(3...)
Affinity DataIC50: 49nMAssay Description:The inhibitory activity of compounds is determined in competitive binding assays. This spectrophotometric assay measures the binding of biotinylated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
Go to US Patent

TargetGalectin-1(Human)
Galecto Biotech

US Patent
LigandPNGBDBM508744(US11046725, Example 21 | 3,5-dibromo-4-fluoropheny...)
Affinity DataKd:  50nMAssay Description:The affinity of Example 1-33 for galectins were determined by a fluorescence anisotropy assay where the compound was used as an inhibitor of the inte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2021
Entry Details
Go to US Patent

TargetGalectin-1(Human)
Galecto Biotech

US Patent
LigandPNGBDBM667994(US20240124427, Example 110 | (2R,3R,4S,5R,6R)-N-(3...)
Affinity DataIC50: 51nMAssay Description:The inhibitory activity of compounds is determined in competitive binding assays. This spectrophotometric assay measures the binding of biotinylated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
Go to US Patent

TargetGalectin-1(Human)
Galecto Biotech

US Patent
LigandPNGBDBM508753(US11046725, Example 33 | 5-Chloro-N,N′-dimet...)
Affinity DataKd:  54nMAssay Description:The affinity of Example 1-33 for galectins were determined by a fluorescence anisotropy assay where the compound was used as an inhibitor of the inte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2021
Entry Details
Go to US Patent

TargetGalectin-1(Human)
Galecto Biotech

US Patent
LigandPNGBDBM508743(US11046725, Example 20 | 3,4,5-trichlorophenyl 3-d...)
Affinity DataKd:  56nMAssay Description:The affinity of Example 1-33 for galectins were determined by a fluorescence anisotropy assay where the compound was used as an inhibitor of the inte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2021
Entry Details
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TargetGalectin-1(Human)
Galecto Biotech

US Patent
LigandPNGBDBM50635331(CHEMBL5557673)
Affinity DataKd:  57nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetGalectin-1(Human)
Galecto Biotech

US Patent
LigandPNGBDBM737631((2R,3R,4S,5R,6R)-N-(3,5-dichlorophenyl)-4-(4-(3-fl...)
Affinity DataIC50: 58nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/5/2025
Entry Details
Go to US Patent

TargetGalectin-1(Human)
Galecto Biotech

US Patent
LigandPNGBDBM508736(US11046725, Example 12 | 3,4-Dichlorophenyl 3-deox...)
Affinity DataKd:  58nMAssay Description:The affinity of Example 1-33 for galectins were determined by a fluorescence anisotropy assay where the compound was used as an inhibitor of the inte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2021
Entry Details
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TargetGalectin-1(Human)
Galecto Biotech

US Patent
LigandPNGBDBM455404(3,3′-Dideoxy-3-[4-(tetrahydropyran-4-yl)-1H-...)
Affinity DataKd:  58nMAssay Description:The affinity of Example 1-5 for galectins were determined by a fluorescence anisotropy assay where the compound was used as an inhibitor of the inter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2021
Entry Details
Go to US Patent

TargetGalectin-1(Human)
Galecto Biotech

US Patent
LigandPNGBDBM468295(US10800804, Example SX | 3,3′-Dideoxy-3,3...)
Affinity DataKd:  60nMAssay Description:The affinity of compounds S8a-c, S11, S16, S20a-b and S21 for galectins were determined by a fluorescence anisotropy assay where the compound was use...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
Go to US Patent

TargetGalectin-1(Human)
Galecto Biotech

US Patent
LigandPNGBDBM468295(US10800804, Example SX | 3,3′-Dideoxy-3,3...)
Affinity DataKd:  60nMAssay Description:The affinity of compounds S8a-c, S11, S16, S20a-b and S21 for galectins were determined by a fluorescence anisotropy assay where the compound was use...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
Go to US Patent

TargetGalectin-1(Human)
Galecto Biotech

US Patent
LigandPNGBDBM50247478(CHEMBL4066068)
Affinity DataKd:  63nMAssay Description:Displacement of 3,3'-dideoxy-3-[4-(fluorescein-5-yl-carbonylaminomethyl)-1H-1,2,3-triazol-1-yl]-3'-(3,5-dimethoxy-benzamido)-1,1'-sulfanediyl-di-beta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2019
Entry Details Article
PubMed
TargetGalectin-1(Human)
Galecto Biotech

US Patent
LigandPNGBDBM508745(US11046725, Example 22 | 3-Bromo-4-cyanophenyl 3-d...)
Affinity DataKd:  63nMAssay Description:The affinity of Example 1-33 for galectins were determined by a fluorescence anisotropy assay where the compound was used as an inhibitor of the inte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2021
Entry Details
Go to US Patent

TargetGalectin-1(Human)
Galecto Biotech

US Patent
LigandPNGBDBM746525(tert-butyl 4-((RS)-5-(((2R,3R,4S,5R,6R)-4-(4-(4-br...)
Affinity DataIC50: 65nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/25/2025
Entry Details
Go to US Patent

TargetGalectin-1(Human)
Galecto Biotech

US Patent
LigandPNGBDBM468294(US10800804, Example S21 | 3,3′-Dideoxy-3-[4-...)
Affinity DataKd:  66nMAssay Description:The affinity of compounds S8a-c, S11, S16, S20a-b and S21 for galectins were determined by a fluorescence anisotropy assay where the compound was use...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
Go to US Patent

TargetGalectin-1(Human)
Galecto Biotech

US Patent
LigandPNGBDBM746708(N-(tert-butyl)-4-(4-(((2R,3R,4S,5R,6R)-5-hydroxy-6...)
Affinity DataIC50: 67nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/25/2025
Entry Details
Go to US Patent

TargetGalectin-1(Human)
Galecto Biotech

US Patent
LigandPNGBDBM508733(US11046725, Example 6 | 5-Bromo-6-cyano-3-pyridyl ...)
Affinity DataKd:  68nMAssay Description:The affinity of Example 1-33 for galectins were determined by a fluorescence anisotropy assay where the compound was used as an inhibitor of the inte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2021
Entry Details
Go to US Patent

TargetGalectin-1(Human)
Galecto Biotech

US Patent
LigandPNGBDBM50247479(CHEMBL4104417)
Affinity DataKd:  69nMAssay Description:Displacement of 3,3'-dideoxy-3-[4-(fluorescein-5-yl-carbonylaminomethyl)-1H-1,2,3-triazol-1-yl]-3'-(3,5-dimethoxy-benzamido)-1,1'-sulfanediyl-di-beta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2019
Entry Details Article
PubMed
TargetGalectin-1(Human)
Galecto Biotech

US Patent
LigandPNGBDBM455405(3,3′-Dideoxy-3-[4-(propan-2-yl)-1H-1,2,3-tri...)
Affinity DataKd:  70nMAssay Description:The affinity of Example 1-5 for galectins were determined by a fluorescence anisotropy assay where the compound was used as an inhibitor of the inter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2021
Entry Details
Go to US Patent

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