Compile Data Set for Download or QSAR
Report error Found 1766 Enz. Inhib. hit(s) with Target = 'Glutathione S-transferase'
TargetGlutathione S-transferase omega-1(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50526135BDBM50526135(CHEMBL4593975)
Affinity DataIC50: 0.220nMAssay Description:Inhibition of CMFDA binding to human N-terminal 6x-His-tagged GSTO1-1 preincubated for 30 mins followed by CMFDA addition and measured after 30 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetGlutathione S-transferase omega-1(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50526136BDBM50526136(CHEMBL4513682)
Affinity DataIC50: 0.320nMAssay Description:Inhibition of CMFDA binding to human N-terminal 6x-His-tagged GSTO1-1 preincubated for 30 mins followed by CMFDA addition and measured after 30 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 218770BDBM218770(US9296757, 92)
Affinity DataIC50: 0.600nMpH: 7.5 T: 2°CAssay Description:For the assay 50 nL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2017
Entry Details
US Patent

TargetGlutathione S-transferase theta-1(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50368152BDBM50368152(CHEMBL318812)
Affinity DataKi:  0.680nMAssay Description:The compound was tested for binding activity against muscarinic acetylcholine receptor M3, using [3H]-QNB as the radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 218771BDBM218771(US9296757, 93)
Affinity DataIC50: 0.700nMpH: 7.5 T: 2°CAssay Description:For the assay 50 nL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2017
Entry Details
US Patent

TargetGlutathione S-transferase P/Tyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 255549BDBM255549(US9499534, 1.2)
Affinity DataIC50: 0.959nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2017
Entry Details
US Patent

TargetGlutathione S-transferase P/Tyrosine-protein kinase JAK1(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 257460BDBM257460(US9493441, 8)
Affinity DataIC50: 1nMT: 2°CAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2017
Entry Details
US Patent

TargetGlutathione S-transferase P/Tyrosine-protein kinase JAK1(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 257457BDBM257457(US9493441, 6-3)
Affinity DataIC50: 1nMT: 2°CAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2017
Entry Details
US Patent

TargetGlutathione S-transferase P/Tyrosine-protein kinase JAK1(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 257458BDBM257458(US9493441, 6-4)
Affinity DataIC50: 1nMT: 2°CAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2017
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 795305BDBM795305(US12570648, Example 35)
Affinity DataKi: <1nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/21/2026
Entry Details US Patent

LigandChemical structure of BindingDB Monomer ID 795303BDBM795303(US12570648, Example 32)
Affinity DataKi: <1nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/21/2026
Entry Details US Patent

TargetGlutathione S-transferase P/Tyrosine-protein kinase JAK1(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 257495BDBM257495(US9493441, 19-1)
Affinity DataIC50: 1nMT: 2°CAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2017
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 795302BDBM795302(US12570648, Example 31)
Affinity DataKi: <1nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/21/2026
Entry Details US Patent

LigandChemical structure of BindingDB Monomer ID 795306BDBM795306(US12570648, Example 36)
Affinity DataKi: <1nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/21/2026
Entry Details US Patent

LigandChemical structure of BindingDB Monomer ID 259295BDBM259295(US9499547, 36)
Affinity DataIC50: 1nMpH: 7.5 T: 2°CAssay Description:A recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accession n...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2017
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 218766BDBM218766(US9296757, 88)
Affinity DataIC50: 1nMpH: 7.5 T: 2°CAssay Description:For the assay 50 nL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2017
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 795295BDBM795295(US12570648, Example 24)
Affinity DataKi: <1nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/21/2026
Entry Details US Patent

LigandChemical structure of BindingDB Monomer ID 218768BDBM218768(US9296757, 90)
Affinity DataIC50: 1nMpH: 7.5 T: 2°CAssay Description:For the assay 50 nL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2017
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 795301BDBM795301(US12570648, Example 30)
Affinity DataKi: <1nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/21/2026
Entry Details US Patent

LigandChemical structure of BindingDB Monomer ID 795298BDBM795298(US12570648, Example 27)
Affinity DataKi: <1nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/21/2026
Entry Details US Patent

TargetGlutathione S-transferase P/Tyrosine-protein kinase JAK1(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 257454BDBM257454(US9493441, 5)
Affinity DataIC50: 1nMT: 2°CAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2017
Entry Details
US Patent

TargetGlutathione S-transferase P/Tyrosine-protein kinase JAK1(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 257496BDBM257496(US9493441, 14-1)
Affinity DataIC50: 1nMT: 2°CAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2017
Entry Details
US Patent

TargetGlutathione S-transferase P/Tyrosine-protein kinase JAK1(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 257449BDBM257449(US9493441, 4-33)
Affinity DataIC50: 1nMT: 2°CAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2017
Entry Details
US Patent

TargetGlutathione S-transferase P/Tyrosine-protein kinase JAK1(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 257448BDBM257448(US9493441, 4-32)
Affinity DataIC50: 1nMT: 2°CAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2017
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 795294BDBM795294(US12570648, Example 23)
Affinity DataKi:  1.10nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/21/2026
Entry Details US Patent

TargetGlutathione S-transferase P/Tyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 255564BDBM255564(US9499534, 2.11)
Affinity DataIC50: 1.11nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2017
Entry Details
US Patent

TargetGlutathione S-transferase P/Tyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 255553BDBM255553(US9499534, 1.6)
Affinity DataIC50: 1.29nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2017
Entry Details
US Patent

TargetGlutathione S-transferase P/Tyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 255572BDBM255572(US9499534, 2.19)
Affinity DataIC50: 1.29nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2017
Entry Details
US Patent

TargetGlutathione S-transferase P/Tyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 255552BDBM255552(US9499534, 1.5)
Affinity DataIC50: 1.40nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2017
Entry Details
US Patent

TargetGlutathione S-transferase P/Tyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 255558BDBM255558(US9499534, 2.5)
Affinity DataIC50: 1.56nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2017
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 218767BDBM218767(US9296757, 89)
Affinity DataIC50: 1.90nMpH: 7.5 T: 2°CAssay Description:For the assay 50 nL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2017
Entry Details
US Patent

TargetGlutathione S-transferase P/Tyrosine-protein kinase JAK1(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 257429BDBM257429(BDBM257439 | US9493441, 4-13)
Affinity DataIC50: 2nMT: 2°CAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2017
Entry Details
US Patent

TargetGlutathione S-transferase P/Tyrosine-protein kinase JAK1(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 257459BDBM257459(US9493441, 7)
Affinity DataIC50: 2nMT: 2°CAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2017
Entry Details
US Patent

TargetGlutathione S-transferase P/Tyrosine-protein kinase JAK1(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 257435BDBM257435(US9493441, 4-19)
Affinity DataIC50: 2nMT: 2°CAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2017
Entry Details
US Patent

TargetGlutathione S-transferase P/Tyrosine-protein kinase JAK1(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 257494BDBM257494(US9493441, 18-1)
Affinity DataIC50: 2nMT: 2°CAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2017
Entry Details
US Patent

TargetGlutathione S-transferase P/Tyrosine-protein kinase JAK1(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 257492BDBM257492(US9493441, 17-4)
Affinity DataIC50: 2nMT: 2°CAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2017
Entry Details
US Patent

TargetGlutathione S-transferase P/Tyrosine-protein kinase JAK1(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 257445BDBM257445(US9493441, 4-29)
Affinity DataIC50: 2nMT: 2°CAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2017
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 259295BDBM259295(US9499547, 36)
Affinity DataIC50: 2nMpH: 7.5 T: 2°CAssay Description:MKNK1-inhibitory activity at high ATP of compounds of the present invention after their preincubation with MKNK1 was quantified employing the TR-FRET...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2017
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 218765BDBM218765(US9296757, 87)
Affinity DataIC50: 2nMpH: 7.5 T: 2°CAssay Description:For the assay 50 nL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2017
Entry Details
US Patent

TargetGlutathione S-transferase P/Tyrosine-protein kinase JAK1(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 257429BDBM257429(BDBM257439 | US9493441, 4-13)
Affinity DataIC50: 2nMT: 2°CAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2017
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 795288BDBM795288(US12570648, Example 17)
Affinity DataKi:  2nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/21/2026
Entry Details US Patent

TargetGlutathione S-transferase P/Tyrosine-protein kinase JAK1(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 257451BDBM257451(US9493441, 4-35)
Affinity DataIC50: 2nMT: 2°CAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2017
Entry Details
US Patent

TargetGlutathione S-transferase P/Tyrosine-protein kinase JAK1(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 257418BDBM257418(US9493441, 4-2)
Affinity DataIC50: 2nMT: 2°CAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2017
Entry Details
US Patent

TargetGlutathione S-transferase P/Tyrosine-protein kinase JAK1(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 257450BDBM257450(US9493441, 4-34)
Affinity DataIC50: 2nMT: 2°CAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2017
Entry Details
US Patent

TargetGlutathione S-transferase P/Tyrosine-protein kinase JAK1(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 257447BDBM257447(US9493441, 4-31)
Affinity DataIC50: 2nMT: 2°CAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2017
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 795286BDBM795286(US12570648, Example 15)
Affinity DataKi:  2.30nMAssay Description:Cell-based activity under Prompt Conditions. Rat or human NHE3-mediated Na+-dependent H+ antiport was measured using a modification of the pH sensiti...More data for this Ligand-Target Pair
Ligand InfoPDB
In Depth
Date in BDB:
7/21/2026
Entry Details US Patent

TargetGlutathione S-transferase P/Tyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 255563BDBM255563(US9499534, 2.10)
Affinity DataIC50: 2.38nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2017
Entry Details
US Patent

TargetGlutathione S-transferase P/Tyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 255584BDBM255584(US9499534, 3.1)
Affinity DataIC50: 2.5nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2017
Entry Details
US Patent

TargetGlutathione S-transferase P/Tyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 255579BDBM255579(US9499534, 2.26)
Affinity DataIC50: 2.68nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2017
Entry Details
US Patent

TargetGlutathione S-transferase P/Tyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 255581BDBM255581(US9499534, 2.28)
Affinity DataIC50: 2.75nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2017
Entry Details
US Patent

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