Compile Data Set for Download or QSAR
Report error Found 38 Enz. Inhib. hit(s) with Target = 'Glycine receptor subunit alpha-2'
TargetGlycine receptor subunit alpha-2(Human)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50411311BDBM50411311(CHEMBL2113267)
Affinity DataIC50: 1.30E+3nMAssay Description:Activity at human alpha-2GlyR expressed in HEK293 cells by FMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlycine receptor subunit alpha-2(Human)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50292287BDBM50292287(CHEMBL465161 | ginkgolide-A | GINKGOLIDE A)
Affinity DataIC50: 2.10E+3nMAssay Description:Activity at human alpha-2GlyR expressed in HEK293 cells by FMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlycine receptor subunit alpha-2(Rat)
Université

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50017684BDBM50017684(PICROTOXININ1-hydroxy-14-isopropenyl-13-methyl-(1R...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of rat alpha2 homomeric glycine receptor expressed in CHO cells assessed as inhibition of 300 uM glycine-elicited current by outside patch...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGlycine receptor subunit alpha-2(Human)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50318484BDBM50318484(CHEMBL190461 | 2-((1R,6R)-6-Isopropenyl-3-methyl-c...)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of human strychnine-insensitive glycine receptor alpha 2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetGlycine receptor subunit alpha-2(Human)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50251276BDBM50251276(CHEMBL514432 | BN 52021 | ginkgolide B | Gingkolid...)
Affinity DataIC50: 3.70E+3nMAssay Description:Activity at human alpha-2GlyR expressed in HEK293 cells by FMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlycine receptor subunit alpha-2(Human)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50208068BDBM50208068((1R,3R,6R,7S,8S,9S,10R,11R,12R,13S,16S,17R)-8-tert...)
Affinity DataIC50: 4.60E+3nMAssay Description:Activity at human alpha-2GlyR expressed in HEK293 cells by FMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlycine receptor subunit alpha-2(Human)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50208060BDBM50208060(10-methoxy-ginkgolide C | CHEMBL221823)
Affinity DataIC50: 7.80E+3nMAssay Description:Activity at human alpha-2GlyR expressed in HEK293 cells by FMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlycine receptor subunit alpha-2(Human)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50208073BDBM50208073(ginkgolide C | CHEMBL221821)
Affinity DataIC50: 8.20E+3nMAssay Description:Activity at human alpha-2GlyR expressed in HEK293 cells by FMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlycine receptor subunit alpha-2(Human)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50208076BDBM50208076(3,14-didehydroginkgolide A | CHEMBL373969)
Affinity DataIC50: 9.50E+3nMAssay Description:Activity at human alpha-2GlyR expressed in HEK293 cells by FMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlycine receptor subunit alpha-2(Human)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50208085BDBM50208085((3S,8R,12R,16S,17R,21S)-3-tert-butyl-17-hydroxy-16...)
Affinity DataIC50: 1.20E+4nMAssay Description:Activity at human alpha-2GlyR expressed in HEK293 cells by FMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlycine receptor subunit alpha-2(Human)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50208074BDBM50208074(ginkgolide J | CHEMBL374004)
Affinity DataIC50: 1.20E+4nMAssay Description:Activity at human alpha-2GlyR expressed in HEK293 cells by FMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlycine receptor subunit alpha-2(Human)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50208081BDBM50208081((1R,3R,6R,7S,8S,9S,10R,11R,12R,13S,16S,17R)-8-tert...)
Affinity DataIC50: 1.30E+4nMAssay Description:Activity at human alpha-2GlyR expressed in HEK293 cells by FMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlycine receptor subunit alpha-2(Human)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50208082BDBM50208082((1R,3R,6R,7S,8S,9S,10S,11R,12R,13S,16S,17R)-9-azid...)
Affinity DataIC50: 2.90E+4nMAssay Description:Activity at human alpha-2GlyR expressed in HEK293 cells by FMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlycine receptor subunit alpha-2/beta(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50459893BDBM50459893(Gelsemine)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of recombinant human glycine receptor alpha2beta expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetGlycine receptor subunit alpha-2(Human)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50208089BDBM50208089((1R,6R,8S,11S,13S,16R,17R)-8-tert-butyl-16-methyl-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Activity at human alpha-2GlyR expressed in HEK293 cells by FMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlycine receptor subunit alpha-2(Human)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50208090BDBM50208090((1S,8S,11S,13S,16S,17R)-8-tert-butyl-17-hydroxy-16...)
Affinity DataIC50: 1.00E+5nMAssay Description:Activity at human alpha-2GlyR expressed in HEK293 cells by FMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlycine receptor subunit alpha-2(Human)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50208066BDBM50208066((1R,2R,3S,6S,8S,10R,11R)-10-tert-butyl-2,11,16-tri...)
Affinity DataIC50: 1.00E+5nMAssay Description:Activity at human alpha-2GlyR expressed in HEK293 cells by FMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlycine receptor subunit alpha-2(Human)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50208092BDBM50208092((1S,6R,8S,9S,11R,12R,13S,16S,17R)-8-tert-butyl-6,1...)
Affinity DataIC50: 1.00E+5nMAssay Description:Activity at human alpha-2GlyR expressed in HEK293 cells by FMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlycine receptor subunit alpha-2(Human)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50208070BDBM50208070((1S,6R,8S,9S,11R,12R,13S,16S,17R)-8-tert-butyl-6,9...)
Affinity DataIC50: 1.00E+5nMAssay Description:Activity at human alpha-2GlyR expressed in HEK293 cells by FMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlycine receptor subunit alpha-2(Human)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50208088BDBM50208088(methyl 2-[(1R,6R,8S,11S,14R)-8-tert-butyl-6-hydrox...)
Affinity DataIC50: 1.00E+5nMAssay Description:Activity at human alpha-2GlyR expressed in HEK293 cells by FMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlycine receptor subunit alpha-2(Human)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50208079BDBM50208079((1R,6R,8S,11R)-8-tert-butyl-13-methoxy-5,15,16-tri...)
Affinity DataIC50: 1.00E+5nMAssay Description:Activity at human alpha-2GlyR expressed in HEK293 cells by FMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlycine receptor subunit alpha-2(Human)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50208075BDBM50208075((1S,6R,8S,11S,13S,16R,17R)-8-tert-butyl-6,17-dihyd...)
Affinity DataIC50: 1.00E+5nMAssay Description:Activity at human alpha-2GlyR expressed in HEK293 cells by FMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlycine receptor subunit alpha-2(Human)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50208087BDBM50208087(10-acetoxy-ginkgolide B | CHEMBL222222)
Affinity DataIC50: 1.00E+5nMAssay Description:Activity at human alpha-2GlyR expressed in HEK293 cells by FMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlycine receptor subunit alpha-2(Human)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50208086BDBM50208086((1S,6R,8S,9S,11R,12R,13S,16S,17R)-8-tert-butyl-6,1...)
Affinity DataIC50: 1.00E+5nMAssay Description:Activity at human alpha-2GlyR expressed in HEK293 cells by FMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlycine receptor subunit alpha-2(Human)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50208077BDBM50208077((1S,6R,8S,9R,11S,12R,13S,16S,17R)-8-tert-butyl-6,1...)
Affinity DataIC50: 1.00E+5nMAssay Description:Activity at human alpha-2GlyR expressed in HEK293 cells by FMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlycine receptor subunit alpha-2(Human)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50208063BDBM50208063(10-methoxymethyloxy-ginkgolide A | CHEMBL225470)
Affinity DataIC50: 1.00E+5nMAssay Description:Activity at human alpha-2GlyR expressed in HEK293 cells by FMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlycine receptor subunit alpha-2(Human)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50208091BDBM50208091((1S,6R,8S,11R,12R,13S,16S,17R)-8-tert-butyl-6,12,1...)
Affinity DataIC50: 1.00E+5nMAssay Description:Activity at human alpha-2GlyR expressed in HEK293 cells by FMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlycine receptor subunit alpha-2(Human)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50208078BDBM50208078((6R,8S,11S,16R,17S)-8-tert-butyl-6,16,17-trihydrox...)
Affinity DataIC50: 1.00E+5nMAssay Description:Activity at human alpha-2GlyR expressed in HEK293 cells by FMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlycine receptor subunit alpha-2(Human)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50208080BDBM50208080(1,2;3,14-dianhydro-ginkgolide C | CHEMBL412540)
Affinity DataIC50: 1.00E+5nMAssay Description:Activity at human alpha-2GlyR expressed in HEK293 cells by FMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlycine receptor subunit alpha-2(Human)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50208072BDBM50208072((1S,2R,3S,6S,8S,10R)-10-tert-butyl-2-hydroxy-3-met...)
Affinity DataIC50: 1.00E+5nMAssay Description:Activity at human alpha-2GlyR expressed in HEK293 cells by FMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlycine receptor subunit alpha-2(Human)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50208061BDBM50208061((1S,6R,8S,9S,11R,12R,13S,16S,17R)-8-tert-butyl-9-(...)
Affinity DataIC50: 1.00E+5nMAssay Description:Activity at human alpha-2GlyR expressed in HEK293 cells by FMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlycine receptor subunit alpha-2(Human)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50208067BDBM50208067(methyl (2R)-2-[(1S,2R,3S,6S,8S,10S)-10-tert-butyl-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Activity at human alpha-2GlyR expressed in HEK293 cells by FMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlycine receptor subunit alpha-2(Human)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50208059BDBM50208059(CHEMBL412384)
Affinity DataIC50: 1.00E+5nMAssay Description:Activity at human alpha-2GlyR expressed in HEK293 cells by FMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlycine receptor subunit alpha-2(Human)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50208065BDBM50208065(methyl 2-[(1R,6R,8S,11S,14E)-8-tert-butyl-6-hydrox...)
Affinity DataIC50: 1.00E+5nMAssay Description:Activity at human alpha-2GlyR expressed in HEK293 cells by FMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlycine receptor subunit alpha-2(Human)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50208083BDBM50208083((1S,6R,8S,11S,13R,16R,17R)-8-tert-butyl-6,17-dihyd...)
Affinity DataIC50: 1.00E+5nMAssay Description:Activity at human alpha-2GlyR expressed in HEK293 cells by FMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlycine receptor subunit alpha-2(Human)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50208062BDBM50208062((1R,6R,8S,11S)-8-tert-butyl-6,13-dimethoxy-2,4,14,...)
Affinity DataIC50: 1.00E+5nMAssay Description:Activity at human alpha-2GlyR expressed in HEK293 cells by FMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlycine receptor subunit alpha-2(Human)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50208069BDBM50208069((1S,6R,8S,9S,11R,12R,13S,16S,17R)-8-tert-butyl-6,1...)
Affinity DataIC50: 1.00E+5nMAssay Description:Activity at human alpha-2GlyR expressed in HEK293 cells by FMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlycine receptor subunit alpha-2(Rat)
Université

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50269961BDBM50269961(picrotin | CHEMBL478523)
Affinity DataIC50: 1.17E+5nMAssay Description:Inhibition of rat alpha2 homomeric glycine receptor expressed in CHO cells assessed as inhibition of 300 uM glycine-elicited current by outside patch...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed