Compile Data Set for Download or QSAR
Report error Found 213 Enz. Inhib. hit(s) with Target = 'Heat shock protein 75 kDa, mitochondrial'
TargetHeat shock protein 75 kDa, mitochondrial(Human)
Shanghai Leado Pharmatech Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 718142BDBM718142(US20250042884, Compound I-8)
Affinity DataIC50: 3nMAssay Description:Ion Works Barracuda (IWB) automated patch clamp detection was used as test method: HEK293 cells stably expressing TRPA1 were placed in DMEM medium co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/12/2025
Entry Details
US Patent

TargetHeat shock protein 75 kDa, mitochondrial(Human)
Shanghai Leado Pharmatech Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 718139BDBM718139(US20250042884, Compound I-4)
Affinity DataIC50: 3nMAssay Description:Ion Works Barracuda (IWB) automated patch clamp detection was used as test method: HEK293 cells stably expressing TRPA1 were placed in DMEM medium co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/12/2025
Entry Details
US Patent

TargetHeat shock protein 75 kDa, mitochondrial(Human)
Shanghai Leado Pharmatech Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 718140BDBM718140(US20250042884, Compound I-5)
Affinity DataIC50: 3nMAssay Description:Ion Works Barracuda (IWB) automated patch clamp detection was used as test method: HEK293 cells stably expressing TRPA1 were placed in DMEM medium co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/12/2025
Entry Details
US Patent

TargetHeat shock protein 75 kDa, mitochondrial(Human)
Shanghai Leado Pharmatech Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 718138BDBM718138(US20250042884, Compound I-3)
Affinity DataIC50: 3nMAssay Description:Ion Works Barracuda (IWB) automated patch clamp detection was used as test method: HEK293 cells stably expressing TRPA1 were placed in DMEM medium co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/12/2025
Entry Details
US Patent

TargetHeat shock protein 75 kDa, mitochondrial(Human)
Shanghai Leado Pharmatech Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 718136BDBM718136(US20250042884, Compound I-1)
Affinity DataIC50: 3nMAssay Description:Ion Works Barracuda (IWB) automated patch clamp detection was used as test method: HEK293 cells stably expressing TRPA1 were placed in DMEM medium co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/12/2025
Entry Details
US Patent

TargetHeat shock protein 75 kDa, mitochondrial(Human)
Shanghai Leado Pharmatech Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 50439624BDBM50439624(CHEMBL1910764)
Affinity DataKd:  5.80nMAssay Description:Binding affinity to recombinant human Trap-1 by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetHeat shock protein 75 kDa, mitochondrial(Human)
Shanghai Leado Pharmatech Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 50439623BDBM50439623(CHEMBL2419342)
Affinity DataKd:  5.90nMAssay Description:Binding affinity to recombinant human Trap-1 by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetHeat shock protein 75 kDa, mitochondrial(Human)
Shanghai Leado Pharmatech Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 718143BDBM718143(US20250042884, Compound I-9)
Affinity DataIC50: 8nMAssay Description:Ion Works Barracuda (IWB) automated patch clamp detection was used as test method: HEK293 cells stably expressing TRPA1 were placed in DMEM medium co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/12/2025
Entry Details
US Patent

TargetHeat shock protein 75 kDa, mitochondrial(Human)
Shanghai Leado Pharmatech Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 718144BDBM718144(US20250042884, Compound I-11)
Affinity DataIC50: 8nMAssay Description:Ion Works Barracuda (IWB) automated patch clamp detection was used as test method: HEK293 cells stably expressing TRPA1 were placed in DMEM medium co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/12/2025
Entry Details
US Patent

TargetHeat shock protein 75 kDa, mitochondrial(Human)
Shanghai Leado Pharmatech Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 718141BDBM718141(US20250042884, Compound I-6)
Affinity DataIC50: 8nMAssay Description:Ion Works Barracuda (IWB) automated patch clamp detection was used as test method: HEK293 cells stably expressing TRPA1 were placed in DMEM medium co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/12/2025
Entry Details
US Patent

TargetHeat shock protein 75 kDa, mitochondrial(Human)
Shanghai Leado Pharmatech Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 718137BDBM718137(US20250042884, Compound I-2)
Affinity DataIC50: 8nMAssay Description:Ion Works Barracuda (IWB) automated patch clamp detection was used as test method: HEK293 cells stably expressing TRPA1 were placed in DMEM medium co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/12/2025
Entry Details
US Patent

TargetHeat shock protein 75 kDa, mitochondrial(Human)
Shanghai Leado Pharmatech Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 50274535BDBM50274535(CHEMBL4126250)
Affinity DataKd:  10nMAssay Description:Inhibition of FITC-geldanamycin binding to recombinant human N-terminal His6-tagged TRAP1 (60 to 704 residues) expressed in Escherichia coli BL21-Cod...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2020
Entry Details Article
PubMed
TargetHeat shock protein 75 kDa, mitochondrial(Human)
Shanghai Leado Pharmatech Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 718145BDBM718145(US20250042884, Comparative Compound 2)
Affinity DataIC50: 15.5nMAssay Description:Ion Works Barracuda (IWB) automated patch clamp detection was used as test method: HEK293 cells stably expressing TRPA1 were placed in DMEM medium co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/12/2025
Entry Details
US Patent

TargetHeat shock protein 75 kDa, mitochondrial(Human)
Shanghai Leado Pharmatech Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 20926BDBM20926(5-[2,4-dihydroxy-5-(propan-2-yl)phenyl]-N-ethyl-4-...)
Affinity DataKi:  16nMAssay Description:Binding affinity to human recombinant TRAP1 after 3 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetHeat shock protein 75 kDa, mitochondrial(Human)
Shanghai Leado Pharmatech Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 50136674BDBM50136674((R)-duloxetine | LY248685 | (3R)-N-methyl-3-(1-nap...)
Affinity DataIC50: 35.5nMAssay Description:Ion Works Barracuda (IWB) automated patch clamp detection was used as test method: HEK293 cells stably expressing TRPA1 were placed in DMEM medium co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2025
Entry Details
US Patent

TargetHeat shock protein 75 kDa, mitochondrial(Human)
Shanghai Leado Pharmatech Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 50439621BDBM50439621(STA-9090 | GANETESPIB)
Affinity DataIC50: 38nMAssay Description:Inhibition of TRAP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetHeat shock protein 75 kDa, mitochondrial(Human)
Shanghai Leado Pharmatech Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 20926BDBM20926(5-[2,4-dihydroxy-5-(propan-2-yl)phenyl]-N-ethyl-4-...)
Affinity DataIC50: 38nMAssay Description:Displacement of 5-(3-(3-(6-amino-8-(6-iodobenzo[d][1,3]dioxol-5-ylthio)-9H-purin-9-yl)propyl)thioureido)-2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetHeat shock protein 75 kDa, mitochondrial(Human)
Shanghai Leado Pharmatech Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 50650777BDBM50650777(CHEMBL5633816)
Affinity DataKd:  40nMAssay Description:Binding affinity to TRAP1 (unknown origin) assessed as dissociation constant incubated for 24 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHeat shock protein 75 kDa, mitochondrial(Human)
Shanghai Leado Pharmatech Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 50650766BDBM50650766(CHEMBL5633903)
Affinity DataKd:  40nMAssay Description:Binding affinity to TRAP1 (unknown origin) assessed as dissociation constant incubated for 24 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHeat shock protein 75 kDa, mitochondrial(Human)
Shanghai Leado Pharmatech Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 50439621BDBM50439621(STA-9090 | GANETESPIB)
Affinity DataIC50: 51nMAssay Description:Displacement of 5-(3-(3-(6-amino-8-(6-iodobenzo[d][1,3]dioxol-5-ylthio)-9H-purin-9-yl)propyl)thioureido)-2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetHeat shock protein 75 kDa, mitochondrial(Human)
Shanghai Leado Pharmatech Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 50439625BDBM50439625(CHEMBL2419341)
Affinity DataKd:  52nMAssay Description:Binding affinity to recombinant human Trap-1 by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetHeat shock protein 75 kDa, mitochondrial(Human)
Shanghai Leado Pharmatech Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 50571897BDBM50571897(CHEMBL4866705)
Affinity DataIC50: 58nMAssay Description:Inhibition of PU-H71-FITC3 binding to recombinant full length TRAP1 (unknown origin) incubated for 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHeat shock protein 75 kDa, mitochondrial(Human)
Shanghai Leado Pharmatech Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 50571903BDBM50571903(CHEMBL4863672)
Affinity DataIC50: 62nMAssay Description:Inhibition of PU-H71-FITC3 binding to recombinant full length TRAP1 (unknown origin) incubated for 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
TargetHeat shock protein 75 kDa, mitochondrial(Human)
Shanghai Leado Pharmatech Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 20800BDBM20800(CHEMBL467399 | 6-chloro-9-[(4-methoxy-3,5-dimethyl...)
Affinity DataKi:  62nMAssay Description:Binding affinity to human recombinant TRAP1 after 3 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHeat shock protein 75 kDa, mitochondrial(Human)
Shanghai Leado Pharmatech Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 50571908BDBM50571908(CHEMBL4864922)
Affinity DataIC50: 64nMAssay Description:Inhibition of PU-H71-FITC3 binding to recombinant full length TRAP1 (unknown origin) incubated for 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
TargetHeat shock protein 75 kDa, mitochondrial(Human)
Shanghai Leado Pharmatech Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 50571896BDBM50571896(CHEMBL4869481)
Affinity DataIC50: 66nMAssay Description:Inhibition of TRAP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetHeat shock protein 75 kDa, mitochondrial(Human)
Shanghai Leado Pharmatech Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 50571896BDBM50571896(CHEMBL4869481)
Affinity DataIC50: 66nMAssay Description:Inhibition of PU-H71-FITC3 binding to recombinant full length TRAP1 (unknown origin) incubated for 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHeat shock protein 75 kDa, mitochondrial(Human)
Shanghai Leado Pharmatech Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 718146BDBM718146(US20250042884, Compound of formula A)
Affinity DataIC50: 75.5nMAssay Description:Ion Works Barracuda (IWB) automated patch clamp detection was used as test method: HEK293 cells stably expressing TRPA1 were placed in DMEM medium co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/12/2025
Entry Details
US Patent

TargetHeat shock protein 75 kDa, mitochondrial(Human)
Shanghai Leado Pharmatech Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 50571901BDBM50571901(CHEMBL4879021)
Affinity DataIC50: 77nMAssay Description:Inhibition of PU-H71-FITC3 binding to recombinant full length TRAP1 (unknown origin) incubated for 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
TargetHeat shock protein 75 kDa, mitochondrial(Human)
Shanghai Leado Pharmatech Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 50240873BDBM50240873(CHEMBL4068596)
Affinity DataIC50: 79nMAssay Description:Inhibition of FITC3-labeled PU-H71 binding to recombinant human N-terminal His6-tagged TRAP1 (60 to 561 residues) expressed in Escherichia coli BL21(...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHeat shock protein 75 kDa, mitochondrial(Human)
Shanghai Leado Pharmatech Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 50650767BDBM50650767(CHEMBL5633571)
Affinity DataKd:  80nMAssay Description:Binding affinity to TRAP1 (unknown origin) assessed as dissociation constant incubated for 24 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHeat shock protein 75 kDa, mitochondrial(Human)
Shanghai Leado Pharmatech Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 50571921BDBM50571921(CHEMBL4866958)
Affinity DataIC50: 82nMAssay Description:Inhibition of PU-H71-FITC3 binding to recombinant full length TRAP1 (unknown origin) incubated for 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
TargetHeat shock protein 75 kDa, mitochondrial(Human)
Shanghai Leado Pharmatech Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 50571910BDBM50571910(CHEMBL4876871)
Affinity DataIC50: 83nMAssay Description:Inhibition of PU-H71-FITC3 binding to recombinant full length TRAP1 (unknown origin) incubated for 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
TargetHeat shock protein 75 kDa, mitochondrial(Human)
Shanghai Leado Pharmatech Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 50650774BDBM50650774(CHEMBL5633012)
Affinity DataKd:  90nMAssay Description:Binding affinity to TRAP1 (unknown origin) assessed as dissociation constant incubated for 24 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHeat shock protein 75 kDa, mitochondrial(Human)
Shanghai Leado Pharmatech Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 50571923BDBM50571923(CHEMBL4863988)
Affinity DataIC50: 90nMAssay Description:Inhibition of PU-H71-FITC3 binding to recombinant full length TRAP1 (unknown origin) incubated for 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
TargetHeat shock protein 75 kDa, mitochondrial(Human)
Shanghai Leado Pharmatech Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 20800BDBM20800(CHEMBL467399 | 6-chloro-9-[(4-methoxy-3,5-dimethyl...)
Affinity DataIC50: 90nMAssay Description:Displacement of 5-(3-(3-(6-amino-8-(6-iodobenzo[d][1,3]dioxol-5-ylthio)-9H-purin-9-yl)propyl)thioureido)-2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHeat shock protein 75 kDa, mitochondrial(Human)
Shanghai Leado Pharmatech Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 50650771BDBM50650771(CHEMBL5632075)
Affinity DataKd:  90nMAssay Description:Binding affinity to TRAP1 (unknown origin) assessed as dissociation constant incubated for 24 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHeat shock protein 75 kDa, mitochondrial(Human)
Shanghai Leado Pharmatech Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 50571918BDBM50571918(CHEMBL4871630)
Affinity DataIC50: 100nMAssay Description:Inhibition of PU-H71-FITC3 binding to recombinant full length TRAP1 (unknown origin) incubated for 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
TargetHeat shock protein 75 kDa, mitochondrial(Human)
Shanghai Leado Pharmatech Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 50240875BDBM50240875(CHEMBL4080323)
Affinity DataIC50: 138nMAssay Description:Inhibition of FITC3-labeled PU-H71 binding to recombinant human N-terminal His6-tagged TRAP1 (60 to 561 residues) expressed in Escherichia coli BL21(...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHeat shock protein 75 kDa, mitochondrial(Human)
Shanghai Leado Pharmatech Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 50240873BDBM50240873(CHEMBL4068596)
Affinity DataIC50: 143nMAssay Description:Inhibition of PU-H71-FITC3 binding to recombinant full length TRAP1 (unknown origin) incubated for 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHeat shock protein 75 kDa, mitochondrial(Human)
Shanghai Leado Pharmatech Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 50650776BDBM50650776(CHEMBL5631806)
Affinity DataKd:  160nMAssay Description:Binding affinity to TRAP1 (unknown origin) assessed as dissociation constant incubated for 24 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHeat shock protein 75 kDa, mitochondrial(Human)
Shanghai Leado Pharmatech Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 50571900BDBM50571900(CHEMBL4857569)
Affinity DataIC50: 170nMAssay Description:Inhibition of PU-H71-FITC3 binding to recombinant full length TRAP1 (unknown origin) incubated for 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
TargetHeat shock protein 75 kDa, mitochondrial(Human)
Shanghai Leado Pharmatech Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 50571909BDBM50571909(CHEMBL4860652)
Affinity DataIC50: 178nMAssay Description:Inhibition of PU-H71-FITC3 binding to recombinant full length TRAP1 (unknown origin) incubated for 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
TargetHeat shock protein 75 kDa, mitochondrial(Human)
Shanghai Leado Pharmatech Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 50180302BDBM50180302(8-[(6-IODO-1,3-BENZODIOXOL-5-YL)THIO]-9-[3-(ISOPRO...)
Affinity DataIC50: 192nMAssay Description:Inhibition of PU-H71-FITC3 binding to recombinant full length TRAP1 (unknown origin) incubated for 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHeat shock protein 75 kDa, mitochondrial(Human)
Shanghai Leado Pharmatech Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 50031735BDBM50031735(CHEMBL3360305)
Affinity DataIC50: 200nMAssay Description:Inhibition of recombinant human N-terminal His6-tagged TRAP1 (60 to 704 residues) ATPase activity expressed in Escherichia coli BL21-CodonPlus-RIL af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2020
Entry Details Article
PubMed
TargetHeat shock protein 75 kDa, mitochondrial(Human)
Shanghai Leado Pharmatech Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 50180302BDBM50180302(8-[(6-IODO-1,3-BENZODIOXOL-5-YL)THIO]-9-[3-(ISOPRO...)
Affinity DataIC50: 205nMAssay Description:Displacement of PU-FITC3 from recombinant TRAP-1 (unknown origin) after 24 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHeat shock protein 75 kDa, mitochondrial(Human)
Shanghai Leado Pharmatech Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 50180302BDBM50180302(8-[(6-IODO-1,3-BENZODIOXOL-5-YL)THIO]-9-[3-(ISOPRO...)
Affinity DataIC50: 205nMAssay Description:Displacement of 5-(3-(3-(6-amino-8-(6-iodobenzo[d][1,3]dioxol-5-ylthio)-9H-purin-9-yl)propyl)thioureido)-2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHeat shock protein 75 kDa, mitochondrial(Human)
Shanghai Leado Pharmatech Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 50571922BDBM50571922(CHEMBL4850126)
Affinity DataIC50: 230nMAssay Description:Inhibition of PU-H71-FITC3 binding to recombinant full length TRAP1 (unknown origin) incubated for 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
TargetHeat shock protein 75 kDa, mitochondrial(Human)
Shanghai Leado Pharmatech Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 50650763BDBM50650763(CHEMBL5633174)
Affinity DataKd:  230nMAssay Description:Binding affinity to TRAP1 (unknown origin) assessed as dissociation constant incubated for 24 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHeat shock protein 75 kDa, mitochondrial(Human)
Shanghai Leado Pharmatech Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 50180302BDBM50180302(8-[(6-IODO-1,3-BENZODIOXOL-5-YL)THIO]-9-[3-(ISOPRO...)
Affinity DataKd:  240nMAssay Description:Binding affinity to TRAP1 (unknown origin) assessed as dissociation constant incubated for 24 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
Displayed 1 to 50 (of 213 total ) | Next | Last >>
Jump to: