Compile Data Set for Download or QSAR
Report error Found 634 Enz. Inhib. hit(s) with Target = 'Hematopoietic prostaglandin D synthase'
TargetHematopoietic prostaglandin D synthase(Human)
Riken Center For Biosystems Dynamics Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50463721BDBM50463721(CHEMBL4238290)
Affinity DataKd:  0.140nMAssay Description:Binding affinity to full length recombinant human N-terminal His6-tagged H-PGDS expressed in Escherichia coli BL21(DE3) by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetHematopoietic prostaglandin D synthase(Human)
Riken Center For Biosystems Dynamics Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50385150BDBM50385150(CHEMBL2035650)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of HPGDSMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetHematopoietic prostaglandin D synthase(Human)
Riken Center For Biosystems Dynamics Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50615780BDBM50615780(CHEMBL5285108)
Affinity DataKd:  0.240nMAssay Description:Binding affinity to human H-PGDS expressed in Escherichia coli BL21 DE3 cells assessed as equilibrium dissociation constant by measuring changes in i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetHematopoietic prostaglandin D synthase(Human)
Riken Center For Biosystems Dynamics Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 85603BDBM85603(NSC_5311503 | CAS_5311503 | ZK110841)
Affinity DataKi:  0.300nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2012
Entry Details Article
PubMed
TargetHematopoietic prostaglandin D synthase(Human)
Riken Center For Biosystems Dynamics Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50463722BDBM50463722(CHEMBL4238186)
Affinity DataKd:  0.370nMAssay Description:Binding affinity to full length recombinant human N-terminal His6-tagged H-PGDS expressed in Escherichia coli BL21(DE3) by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetHematopoietic prostaglandin D synthase(Human)
Riken Center For Biosystems Dynamics Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 85175BDBM85175(NSC_3080928 | CAS_72814-32-5 | BW245C)
Affinity DataKi:  0.400nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2012
Entry Details Article
PubMed
TargetHematopoietic prostaglandin D synthase(Human)
Riken Center For Biosystems Dynamics Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50526485BDBM50526485(CHEMBL4473072)
Affinity DataKd:  0.5nMAssay Description:Binding affinity to full-length human His6-tagged HPGDS expressed in Escherichia coli BL21 (DE3) by tryptophan fluorescence quenching assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHematopoietic prostaglandin D synthase(Human)
Riken Center For Biosystems Dynamics Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 82213BDBM82213(CAS_41598-07-6 | NSC_114678 | PGD2)
Affinity DataKi:  1.70nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2012
Entry Details Article
PubMed
TargetHematopoietic prostaglandin D synthase(Human)
Riken Center For Biosystems Dynamics Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50385142BDBM50385142(CHEMBL2035651)
Affinity DataIC50: 2.34nMAssay Description:Inhibition of human recombinant HPGDS using PGH2 as substrate assessed as production of PGD2 preincubated for 10 mins prior substrate addition measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetHematopoietic prostaglandin D synthase(Human)
Riken Center For Biosystems Dynamics Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50615811BDBM50615811(CHEMBL5272869)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE3 cells assessed as reduction in PGD2 production using PGH2 as substrate by RapidFire...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHematopoietic prostaglandin D synthase(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50615825BDBM50615825(CHEMBL5266618)
Affinity DataEC50: <2.5nMAssay Description:Inhibition of H-PGDS in rat RBL cells assessed as reduction in A23187-induced PGD2 production pretreated for 30 mins followed by A23187 addition for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHematopoietic prostaglandin D synthase(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50615823BDBM50615823(CHEMBL5289520)
Affinity DataEC50: <2.5nMAssay Description:Inhibition of H-PGDS in rat RBL cells assessed as reduction in A23187-induced PGD2 production pretreated for 30 mins followed by A23187 addition for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHematopoietic prostaglandin D synthase(Human)
Riken Center For Biosystems Dynamics Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 750572BDBM750572(US20250195518, Example 1)
Affinity DataIC50: 3nMAssay Description:The H-PGDS binding inhibitory activity of the test compound was measured by AlphaLISA antagonistic assay. A specific protocol is as follows. In an A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

TargetHematopoietic prostaglandin D synthase(Human)
Riken Center For Biosystems Dynamics Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50463698BDBM50463698(CHEMBL4247050)
Affinity DataIC50: 3nMAssay Description:Inhibition of HPGDS (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetHematopoietic prostaglandin D synthase(Human)
Riken Center For Biosystems Dynamics Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 750585BDBM750585(US20250195518, Example 24)
Affinity DataIC50: 3nMAssay Description:The H-PGDS binding inhibitory activity of the test compound was measured by AlphaLISA antagonistic assay. A specific protocol is as follows. In an A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

TargetHematopoietic prostaglandin D synthase(Human)
Riken Center For Biosystems Dynamics Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 750594BDBM750594(US20250195518, Example 55)
Affinity DataIC50: 3nMAssay Description:The H-PGDS binding inhibitory activity of the test compound was measured by AlphaLISA antagonistic assay. A specific protocol is as follows. In an A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

TargetHematopoietic prostaglandin D synthase(Human)
Riken Center For Biosystems Dynamics Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 750577BDBM750577(US20250195518, Example 6)
Affinity DataIC50: 3nMAssay Description:The H-PGDS binding inhibitory activity of the test compound was measured by AlphaLISA antagonistic assay. A specific protocol is as follows. In an A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

TargetHematopoietic prostaglandin D synthase(Human)
Riken Center For Biosystems Dynamics Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50615823BDBM50615823(CHEMBL5289520)
Affinity DataIC50: 3.10nMAssay Description:Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE3 cells assessed as reduction in PGD2 production using PGH2 as substrate by RapidFire...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHematopoietic prostaglandin D synthase(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50615795BDBM50615795(CHEMBL5279371)
Affinity DataEC50:  3.70nMAssay Description:Inhibition of H-PGDS in rat RBL cells assessed as reduction in A23187-induced PGD2 production pretreated for 30 mins followed by A23187 addition for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHematopoietic prostaglandin D synthase(Human)
Riken Center For Biosystems Dynamics Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50615812BDBM50615812(CHEMBL5289730)
Affinity DataIC50: 3.80nMAssay Description:Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE3 cells assessed as reduction in PGD2 production using PGH2 as substrate by RapidFire...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHematopoietic prostaglandin D synthase(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50615796BDBM50615796(CHEMBL5267588)
Affinity DataEC50:  3.80nMAssay Description:Inhibition of H-PGDS in rat RBL cells assessed as reduction in A23187-induced PGD2 production pretreated for 30 mins followed by A23187 addition for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHematopoietic prostaglandin D synthase(Human)
Riken Center For Biosystems Dynamics Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50615791BDBM50615791(CHEMBL5275536)
Affinity DataIC50: 3.90nMAssay Description:Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE3 cells assessed as reduction in PGD2 production using PGH2 as substrate by RapidFire...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHematopoietic prostaglandin D synthase(Human)
Riken Center For Biosystems Dynamics Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50615775BDBM50615775(CHEMBL5279860)
Affinity DataIC50: 3.90nMAssay Description:Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE3 cells assessed as reduction in PGD2 production using PGH2 as substrate by RapidFire...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHematopoietic prostaglandin D synthase(Human)
Riken Center For Biosystems Dynamics Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50615797BDBM50615797(CHEMBL5282861)
Affinity DataIC50: 3.90nMAssay Description:Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE3 cells assessed as reduction in PGD2 production using PGH2 as substrate by RapidFire...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHematopoietic prostaglandin D synthase(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50615811BDBM50615811(CHEMBL5272869)
Affinity DataEC50:  3.90nMAssay Description:Inhibition of H-PGDS in rat RBL cells assessed as reduction in A23187-induced PGD2 production pretreated for 30 mins followed by A23187 addition for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHematopoietic prostaglandin D synthase(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50615812BDBM50615812(CHEMBL5289730)
Affinity DataEC50:  3.90nMAssay Description:Inhibition of H-PGDS in rat RBL cells assessed as reduction in A23187-induced PGD2 production pretreated for 30 mins followed by A23187 addition for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHematopoietic prostaglandin D synthase(Human)
Riken Center For Biosystems Dynamics Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 179403BDBM179403(US9126973, 8)
Affinity DataIC50: 4nMpH: 8.0 T: 2°CAssay Description:The assay is carried out by the following steps: 1. Inhibitor screening is performed in 100 mM Tris-HCl, pH 8.0 containing 1 mM GSH, 1 mM MgCl.sub.2,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2016
Entry Details
US Patent

TargetHematopoietic prostaglandin D synthase(Human)
Riken Center For Biosystems Dynamics Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 750584BDBM750584(US20250195518, Example 19)
Affinity DataIC50: 4nMAssay Description:The H-PGDS binding inhibitory activity of the test compound was measured by AlphaLISA antagonistic assay. A specific protocol is as follows. In an A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

TargetHematopoietic prostaglandin D synthase(Human)
Riken Center For Biosystems Dynamics Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50615779BDBM50615779(CHEMBL5285125)
Affinity DataIC50: 4.40nMAssay Description:Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE3 cells assessed as reduction in PGD2 production using PGH2 as substrate by RapidFire...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHematopoietic prostaglandin D synthase(Human)
Riken Center For Biosystems Dynamics Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50615800BDBM50615800(CHEMBL5266142)
Affinity DataIC50: 4.60nMAssay Description:Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE3 cells assessed as reduction in PGD2 production using PGH2 as substrate by RapidFire...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHematopoietic prostaglandin D synthase(Human)
Riken Center For Biosystems Dynamics Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50615795BDBM50615795(CHEMBL5279371)
Affinity DataIC50: 4.60nMAssay Description:Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE3 cells assessed as reduction in PGD2 production using PGH2 as substrate by RapidFire...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHematopoietic prostaglandin D synthase(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50615824BDBM50615824(CHEMBL5278680)
Affinity DataEC50:  4.70nMAssay Description:Inhibition of H-PGDS in rat RBL cells assessed as reduction in A23187-induced PGD2 production pretreated for 30 mins followed by A23187 addition for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHematopoietic prostaglandin D synthase(Human)
Riken Center For Biosystems Dynamics Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50615813BDBM50615813(CHEMBL5269778)
Affinity DataIC50: 4.70nMAssay Description:Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE3 cells assessed as reduction in PGD2 production using PGH2 as substrate by RapidFire...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHematopoietic prostaglandin D synthase(Human)
Riken Center For Biosystems Dynamics Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50615802BDBM50615802(CHEMBL5269001)
Affinity DataIC50: 4.80nMAssay Description:Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE3 cells assessed as reduction in PGD2 production using PGH2 as substrate by RapidFire...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHematopoietic prostaglandin D synthase(Human)
Riken Center For Biosystems Dynamics Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50615792BDBM50615792(CHEMBL5279720)
Affinity DataIC50: 4.90nMAssay Description:Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE3 cells assessed as reduction in PGD2 production using PGH2 as substrate by RapidFire...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHematopoietic prostaglandin D synthase(Human)
Riken Center For Biosystems Dynamics Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 750576BDBM750576(US20250195518, Example 4)
Affinity DataIC50: 5nMAssay Description:The H-PGDS binding inhibitory activity of the test compound was measured by AlphaLISA antagonistic assay. A specific protocol is as follows. In an A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

TargetHematopoietic prostaglandin D synthase(Human)
Riken Center For Biosystems Dynamics Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50615824BDBM50615824(CHEMBL5278680)
Affinity DataIC50: 5nMAssay Description:Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE3 cells assessed as reduction in PGD2 production using PGH2 as substrate by RapidFire...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHematopoietic prostaglandin D synthase(Human)
Riken Center For Biosystems Dynamics Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50615825BDBM50615825(CHEMBL5266618)
Affinity DataIC50: 5nMAssay Description:Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE3 cells assessed as reduction in PGD2 production using PGH2 as substrate by RapidFire...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHematopoietic prostaglandin D synthase(Human)
Riken Center For Biosystems Dynamics Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 750597BDBM750597(US20250195518, Example 128)
Affinity DataIC50: 5nMAssay Description:The H-PGDS binding inhibitory activity of the test compound was measured by AlphaLISA antagonistic assay. A specific protocol is as follows. In an A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

TargetHematopoietic prostaglandin D synthase(Human)
Riken Center For Biosystems Dynamics Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50615796BDBM50615796(CHEMBL5267588)
Affinity DataIC50: 5.10nMAssay Description:Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE3 cells assessed as reduction in PGD2 production using PGH2 as substrate by RapidFire...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHematopoietic prostaglandin D synthase(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50615813BDBM50615813(CHEMBL5269778)
Affinity DataEC50:  5.20nMAssay Description:Inhibition of H-PGDS in rat RBL cells assessed as reduction in A23187-induced PGD2 production pretreated for 30 mins followed by A23187 addition for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHematopoietic prostaglandin D synthase(Human)
Riken Center For Biosystems Dynamics Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50615778BDBM50615778(CHEMBL5283521)
Affinity DataIC50: 5.30nMAssay Description:Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE3 cells assessed as reduction in PGD2 production using PGH2 as substrate by RapidFire...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHematopoietic prostaglandin D synthase(Human)
Riken Center For Biosystems Dynamics Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50559393BDBM50559393(CHEMBL4752221)
Affinity DataIC50: 5.90nMAssay Description:Inhibition of HPGDS (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetHematopoietic prostaglandin D synthase(Human)
Riken Center For Biosystems Dynamics Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50576323BDBM50576323(CHEMBL4866146)
Affinity DataIC50: 6nMAssay Description:Inhibition of human HPGDS assessed as reduction in PGD2 formation using PGH2 as substrate by mass spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetHematopoietic prostaglandin D synthase(Human)
Riken Center For Biosystems Dynamics Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50463701BDBM50463701(CHEMBL4241885)
Affinity DataIC50: 6nMAssay Description:Inhibition of HPGDS (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetHematopoietic prostaglandin D synthase(Human)
Riken Center For Biosystems Dynamics Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 179422BDBM179422(US9126973, 19)
Affinity DataIC50: 6nMpH: 8.0 T: 2°CAssay Description:The assay is carried out by the following steps: 1. Inhibitor screening is performed in 100 mM Tris-HCl, pH 8.0 containing 1 mM GSH, 1 mM MgCl.sub.2,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2016
Entry Details
US Patent

TargetHematopoietic prostaglandin D synthase(Human)
Riken Center For Biosystems Dynamics Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50615782BDBM50615782(CHEMBL5282228)
Affinity DataIC50: 6.40nMAssay Description:Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE3 cells assessed as reduction in PGD2 production using PGH2 as substrate by RapidFire...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHematopoietic prostaglandin D synthase(Human)
Riken Center For Biosystems Dynamics Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50615798BDBM50615798(CHEMBL5273656)
Affinity DataIC50: 6.40nMAssay Description:Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE3 cells assessed as reduction in PGD2 production using PGH2 as substrate by RapidFire...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHematopoietic prostaglandin D synthase(Human)
Riken Center For Biosystems Dynamics Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50615810BDBM50615810(CHEMBL5277213)
Affinity DataIC50: 6.60nMAssay Description:Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE3 cells assessed as reduction in PGD2 production using PGH2 as substrate by RapidFire...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHematopoietic prostaglandin D synthase(Human)
Riken Center For Biosystems Dynamics Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 750605BDBM750605(US20250195518, Example 255)
Affinity DataIC50: 7nMAssay Description:The H-PGDS binding inhibitory activity of the test compound was measured by AlphaLISA antagonistic assay. A specific protocol is as follows. In an A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

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