Compile Data Set for Download or QSAR
Report error Found 187 Enz. Inhib. hit(s) with Target = 'High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B'
LigandChemical structure of BindingDB Monomer ID 50344013BDBM50344013(trans-(3R,5S)-N-((6-aminopyridin-2-yl)methyl)-1-((...)
Affinity DataIC50: 0.120nMAssay Description:Inhibition of PDE8BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50594973BDBM50594973(CHEMBL5169811)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of PDE8B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50594973BDBM50594973(CHEMBL5169811)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of PDE8B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50594973BDBM50594973(CHEMBL5169811)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of PDE8B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50390333BDBM50390333(CHEMBL2070733)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of PDE8B expressed in Sf9 insect cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50344014BDBM50344014(trans-(3R,5S)-1-((5-methyl-2-phenyloxazol-4-yl)met...)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of PDE8BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50344015BDBM50344015(trans-(3S,5S)-5-ethyl-1-((5-methyl-2-phenyloxazol-...)
Affinity DataIC50: 0.955nMAssay Description:Inhibition of PDE8BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50390334BDBM50390334(CHEMBL2070735)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of PDE8B expressed in Sf9 insect cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50390332BDBM50390332(CHEMBL2070732)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of PDE8B expressed in Sf9 insect cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50344019BDBM50344019(trans-(3R,5R)-5-(methoxymethyl)-1-((5-methyl-2-phe...)
Affinity DataIC50: 1.96nMAssay Description:Inhibition of PDE8BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50344020BDBM50344020(trans-(3R,5R)-5-ethyl-1-((5-methyl-2-phenyloxazol-...)
Affinity DataIC50: 2.91nMAssay Description:Inhibition of PDE8BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50344021BDBM50344021(trans-(3R,5R)-5-(methoxymethyl)-1-((5-methyl-2-phe...)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of PDE8BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50390373BDBM50390373(CHEMBL2070914)
Affinity DataIC50: 3.63nMAssay Description:Inhibition of PDE8B expressed in Sf9 insect cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50344022BDBM50344022(trans-(3S,5S)-5-(3-methyl-1,2,4-oxadiazol-5-yl)-1-...)
Affinity DataIC50: 3.86nMAssay Description:Inhibition of PDE8BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50344023BDBM50344023(trans-(3R,5R)-5-(3-methyl-1,2,4-oxadiazol-5-yl)-1-...)
Affinity DataIC50: 3.90nMAssay Description:Inhibition of PDE8BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50390335BDBM50390335(CHEMBL2070736)
Affinity DataIC50: 4.20nMAssay Description:Inhibition of PDE8B expressed in Sf9 insect cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50344024BDBM50344024(trans-(3S,5S)-5-(methoxymethyl)-1-((5-methyl-2-phe...)
Affinity DataIC50: 4.30nMAssay Description:Inhibition of PDE8BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50344025BDBM50344025(trans-(3R,5R)-5-(methoxymethyl)-1-((5-methyl-2-phe...)
Affinity DataIC50: 4.36nMAssay Description:Inhibition of PDE8BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50344026BDBM50344026(trans-(3R,5R)-N-((6-aminopyridin-2-yl)methyl)-5-et...)
Affinity DataIC50: 4.42nMAssay Description:Inhibition of PDE8BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50344016BDBM50344016(2-((5-methyl-2-phenyloxazol-4-yl)methyl)-N-((6-met...)
Affinity DataIC50: 5nMAssay Description:Inhibition of PDE8BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50344018BDBM50344018(trans-(3R,5R)-5-ethyl-1-((5-methyl-2-phenyloxazol-...)
Affinity DataIC50: 6nMAssay Description:Inhibition of PDE8BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50344027BDBM50344027(trans-(3R,5R)-1-((5-methyl-2-phenyloxazol-4-yl)met...)
Affinity DataIC50: 6nMAssay Description:Inhibition of PDE8BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50390366BDBM50390366(CHEMBL2070935)
Affinity DataIC50: 6.79nMAssay Description:Inhibition of PDE8B expressed in Sf9 insect cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50390324BDBM50390324(CHEMBL2070604)
Affinity DataIC50: 6.80nMAssay Description:Inhibition of PDE8B expressed in Sf9 insect cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50344028BDBM50344028(trans-(3R,5R)-1-((5-methyl-2-phenyloxazol-4-yl)met...)
Affinity DataIC50: 7nMAssay Description:Inhibition of PDE8BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50344029BDBM50344029(trans-(3R,5R)-5-ethyl-1-((5-methyl-2-phenyloxazol-...)
Affinity DataIC50: 7.30nMAssay Description:Inhibition of PDE8BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50390313BDBM50390313(CHEMBL2070595)
Affinity DataIC50: 10nMAssay Description:Inhibition of PDE8B expressed in Sf9 insect cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50390352BDBM50390352(CHEMBL2070901)
Affinity DataIC50: 12.1nMAssay Description:Inhibition of PDE8B expressed in Sf9 insect cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50344030BDBM50344030(trans-(3R,5R)-5-(methoxymethyl)-1-((5-methyl-2-(py...)
Affinity DataIC50: 13nMAssay Description:Inhibition of PDE8BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50390367BDBM50390367(CHEMBL2070907)
Affinity DataIC50: 13.1nMAssay Description:Inhibition of PDE8B expressed in Sf9 insect cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50390309BDBM50390309(CHEMBL2070591)
Affinity DataIC50: 14nMAssay Description:Inhibition of PDE8B expressed in Sf9 insect cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50390308BDBM50390308(CHEMBL2070592)
Affinity DataIC50: 14nMAssay Description:Inhibition of PDE8B expressed in Sf9 insect cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50344031BDBM50344031(trans-(3R,5R)-5-butyl-1-((5-methyl-2-phenyloxazol-...)
Affinity DataIC50: 15nMAssay Description:Inhibition of PDE8BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50272569BDBM50272569(CHEMBL4128481)
Affinity DataIC50: 16nMAssay Description:Inhibition of full length recombinant human PDE8B using 3',5'-[3H]cAMP as substrate after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50344032BDBM50344032(trans-(3R,5R)-N-((6-aminopyridin-2-yl)methyl)-5-et...)
Affinity DataIC50: 16.5nMAssay Description:Inhibition of PDE8BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50390378BDBM50390378(CHEMBL2070919)
Affinity DataIC50: 17.1nMAssay Description:Inhibition of PDE8B expressed in Sf9 insect cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50390339BDBM50390339(CHEMBL2070769)
Affinity DataIC50: 17.1nMAssay Description:Inhibition of PDE8B expressed in Sf9 insect cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50390371BDBM50390371(CHEMBL2070912)
Affinity DataIC50: 17.1nMAssay Description:Inhibition of PDE8B expressed in Sf9 insect cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50390363BDBM50390363(CHEMBL2070932)
Affinity DataIC50: 17.7nMAssay Description:Inhibition of PDE8B expressed in Sf9 insect cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50390336BDBM50390336(CHEMBL2070737)
Affinity DataIC50: 19nMAssay Description:Inhibition of PDE8B expressed in Sf9 insect cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50344033BDBM50344033(trans-(3R,5R)-5-ethyl-1-((5-methyl-2-phenyloxazol-...)
Affinity DataIC50: 19.6nMAssay Description:Inhibition of PDE8BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50390364BDBM50390364(CHEMBL2070933)
Affinity DataIC50: 21.4nMAssay Description:Inhibition of PDE8B expressed in Sf9 insect cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50390343BDBM50390343(CHEMBL2070773)
Affinity DataIC50: 21.6nMAssay Description:Inhibition of PDE8B expressed in Sf9 insect cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50390338BDBM50390338(CHEMBL2070734)
Affinity DataIC50: 23nMAssay Description:Inhibition of PDE8B expressed in Sf9 insect cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50390329BDBM50390329(CHEMBL2070729)
Affinity DataIC50: 23nMAssay Description:Inhibition of PDE8B expressed in Sf9 insect cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50390320BDBM50390320(CHEMBL2070600)
Affinity DataIC50: 25nMAssay Description:Inhibition of PDE8B expressed in Sf9 insect cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50390375BDBM50390375(CHEMBL2070916)
Affinity DataIC50: 25.5nMAssay Description:Inhibition of PDE8B expressed in Sf9 insect cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50344034BDBM50344034(trans-(3R,5R)-5-ethyl-1-((5-methyl-2-(pyrimidin-4-...)
Affinity DataIC50: 26nMAssay Description:Inhibition of PDE8BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50344035BDBM50344035(trans-(3R,5R)-5-ethyl-1-((5-methyl-2-(pyrimidin-4-...)
Affinity DataIC50: 26.2nMAssay Description:Inhibition of PDE8BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50390384BDBM50390384(CHEMBL2070925)
Affinity DataIC50: 31.5nMAssay Description:Inhibition of PDE8B expressed in Sf9 insect cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
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