Compile Data Set for Download or QSAR
Report error Found 49 Enz. Inhib. hit(s) with Target = 'Histone deacetylase 1/11/4/6/8'
TargetHistone deacetylase 1/11/4/6/8(Human)
Orchid Chemicals & Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 65470BDBM65470(Quinolone-based HDAC inhibitor 4i)
Affinity DataIC50: 0.100nMAssay Description:Histone Deacetylase (HDAC) Inhibition Assay using Boc-Lys(Ac)-AMC Substrate: Inhibition of HDAC has been implicated to modulate transcription and to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2018
Entry Details Article
PubMed
TargetHistone deacetylase 1/11/4/6/8(Human)
Orchid Chemicals & Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 65471BDBM65471(Quinolone-based HDAC inhibitor 4j)
Affinity DataIC50: 1.5nMAssay Description:Histone Deacetylase (HDAC) Inhibition Assay using Boc-Lys(Ac)-AMC Substrate: Inhibition of HDAC has been implicated to modulate transcription and to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2018
Entry Details Article
PubMed
TargetHistone deacetylase 1/11/4/6/8(Human)
Orchid Chemicals & Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 65478BDBM65478(Quinolone-based HDAC inhibitor 4o)
Affinity DataIC50: 10nMAssay Description:Histone Deacetylase (HDAC) Inhibition Assay using Boc-Lys(Ac)-AMC Substrate: Inhibition of HDAC has been implicated to modulate transcription and to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2018
Entry Details Article
PubMed
TargetHistone deacetylase 1/11/4/6/8(Human)
Orchid Chemicals & Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 65481BDBM65481(Quinolone-based HDAC inhibitor 4r)
Affinity DataIC50: 28nMAssay Description:Histone Deacetylase (HDAC) Inhibition Assay using Boc-Lys(Ac)-AMC Substrate: Inhibition of HDAC has been implicated to modulate transcription and to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2018
Entry Details Article
PubMed
TargetHistone deacetylase 1/11/4/6/8(Human)
Orchid Chemicals & Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 65479BDBM65479(Quinolone-based HDAC inhibitor 4p)
Affinity DataIC50: 28nMAssay Description:Histone Deacetylase (HDAC) Inhibition Assay using Boc-Lys(Ac)-AMC Substrate: Inhibition of HDAC has been implicated to modulate transcription and to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2018
Entry Details Article
PubMed
TargetHistone deacetylase 1/11/4/6/8(Human)
Orchid Chemicals & Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 65458BDBM65458(Quinolone-based HDAC inhibitor 4a)
Affinity DataIC50: 32nMAssay Description:Histone Deacetylase (HDAC) Inhibition Assay using Boc-Lys(Ac)-AMC Substrate: Inhibition of HDAC has been implicated to modulate transcription and to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2018
Entry Details Article
PubMed
TargetHistone deacetylase 1/11/4/6/8(Human)
Orchid Chemicals & Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 65475BDBM65475(Quinolone-based HDAC inhibitor 4l)
Affinity DataIC50: 32nMAssay Description:Histone Deacetylase (HDAC) Inhibition Assay using Boc-Lys(Ac)-AMC Substrate: Inhibition of HDAC has been implicated to modulate transcription and to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2018
Entry Details Article
PubMed
TargetHistone deacetylase 1/11/4/6/8(Human)
Orchid Chemicals & Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 65474BDBM65474(Quinolone-based HDAC inhibitor 4k)
Affinity DataIC50: 32nMAssay Description:Histone Deacetylase (HDAC) Inhibition Assay using Boc-Lys(Ac)-AMC Substrate: Inhibition of HDAC has been implicated to modulate transcription and to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2018
Entry Details Article
PubMed
TargetHistone deacetylase 1/11/4/6/8(Human)
Orchid Chemicals & Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 65463BDBM65463(Quinolone-based HDAC inhibitor 4c)
Affinity DataIC50: 39nMAssay Description:Histone Deacetylase (HDAC) Inhibition Assay using Boc-Lys(Ac)-AMC Substrate: Inhibition of HDAC has been implicated to modulate transcription and to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2018
Entry Details Article
PubMed
TargetHistone deacetylase 1/11/4/6/8(Human)
Orchid Chemicals & Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 65485BDBM65485(Quinolone-based HDAC inhibitor 4v)
Affinity DataIC50: 39nMAssay Description:Histone Deacetylase (HDAC) Inhibition Assay using Boc-Lys(Ac)-AMC Substrate: Inhibition of HDAC has been implicated to modulate transcription and to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2018
Entry Details Article
PubMed
TargetHistone deacetylase 1/11/4/6/8(Human)
Orchid Chemicals & Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 65480BDBM65480(Quinolone-based HDAC inhibitor 4q)
Affinity DataIC50: 40nMAssay Description:Histone Deacetylase (HDAC) Inhibition Assay using Boc-Lys(Ac)-AMC Substrate: Inhibition of HDAC has been implicated to modulate transcription and to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2018
Entry Details Article
PubMed
TargetHistone deacetylase 1/11/4/6/8(Human)
Orchid Chemicals & Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 65469BDBM65469(Quinolone-based HDAC inhibitor 4h)
Affinity DataIC50: 42nMAssay Description:Histone Deacetylase (HDAC) Inhibition Assay using Boc-Lys(Ac)-AMC Substrate: Inhibition of HDAC has been implicated to modulate transcription and to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2018
Entry Details Article
PubMed
TargetHistone deacetylase 1/11/4/6/8(Human)
Orchid Chemicals & Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 206287BDBM206287((S)-N1-(3-(1H-indol-3-yl)-1-oxo-1-(p-tolylamino)pr...)
Affinity DataIC50: 74nMAssay Description:In brief, 10 μL of HeLa nuclear extract was mixed with various concentrations of target compounds (50 μL), SAHA, using 100% and none HDACs ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2016
Entry Details Article
PubMed
TargetHistone deacetylase 1/11/4/6/8(Human)
Orchid Chemicals & Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 65476BDBM65476(Quinolone-based HDAC inhibitor 4m)
Affinity DataIC50: 75nMAssay Description:Histone Deacetylase (HDAC) Inhibition Assay using Boc-Lys(Ac)-AMC Substrate: Inhibition of HDAC has been implicated to modulate transcription and to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2018
Entry Details Article
PubMed
TargetHistone deacetylase 1/11/4/6/8(Human)
Orchid Chemicals & Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 206286BDBM206286((S)-N1-(3-(1H-indol-3-yl)-1-((4-iodophenyl)amino)-...)
Affinity DataIC50: 78nMAssay Description:In brief, 10 μL of HeLa nuclear extract was mixed with various concentrations of target compounds (50 μL), SAHA, using 100% and none HDACs ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2016
Entry Details Article
PubMed
TargetHistone deacetylase 1/11/4/6/8(Human)
Orchid Chemicals & Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 65484BDBM65484(Quinolone-based HDAC inhibitor 4u)
Affinity DataIC50: 85nMAssay Description:Histone Deacetylase (HDAC) Inhibition Assay using Boc-Lys(Ac)-AMC Substrate: Inhibition of HDAC has been implicated to modulate transcription and to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2018
Entry Details Article
PubMed
TargetHistone deacetylase 1/11/4/6/8(Human)
Orchid Chemicals & Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 65468BDBM65468(Quinolone-based HDAC inhibitor 4g)
Affinity DataIC50: 90nMAssay Description:Histone Deacetylase (HDAC) Inhibition Assay using Boc-Lys(Ac)-AMC Substrate: Inhibition of HDAC has been implicated to modulate transcription and to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2018
Entry Details Article
PubMed
TargetHistone deacetylase 1/11/4/6/8(Human)
Orchid Chemicals & Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 65472BDBM65472(Quinolone-based HDAC inhibitor 4w)
Affinity DataIC50: 95nMAssay Description:Histone Deacetylase (HDAC) Inhibition Assay using Boc-Lys(Ac)-AMC Substrate: Inhibition of HDAC has been implicated to modulate transcription and to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2018
Entry Details Article
PubMed
TargetHistone deacetylase 1/11/4/6/8(Human)
Orchid Chemicals & Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 206285BDBM206285((S)-N1-(1-((4-bromophenyl)amino)-3-(1H-indol-3-yl)...)
Affinity DataIC50: 96nMAssay Description:In brief, 10 μL of HeLa nuclear extract was mixed with various concentrations of target compounds (50 μL), SAHA, using 100% and none HDACs ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2016
Entry Details Article
PubMed
TargetHistone deacetylase 1/11/4/6/8(Human)
Orchid Chemicals & Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 19149BDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 110nMAssay Description:Histone Deacetylase (HDAC) Inhibition Assay using Boc-Lys(Ac)-AMC Substrate: Inhibition of HDAC has been implicated to modulate transcription and to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 1/11/4/6/8(Human)
Orchid Chemicals & Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 65464BDBM65464(Quinolone-based HDAC inhibitor 4d)
Affinity DataIC50: 120nMAssay Description:Histone Deacetylase (HDAC) Inhibition Assay using Boc-Lys(Ac)-AMC Substrate: Inhibition of HDAC has been implicated to modulate transcription and to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2018
Entry Details Article
PubMed
TargetHistone deacetylase 1/11/4/6/8(Human)
Orchid Chemicals & Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 19149BDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 131nMAssay Description:In brief, 10 μL of HeLa nuclear extract was mixed with various concentrations of target compounds (50 μL), SAHA, using 100% and none HDACs ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 1/11/4/6/8(Human)
Orchid Chemicals & Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 65477BDBM65477(Quinolone-based HDAC inhibitor 4n)
Affinity DataIC50: 150nMAssay Description:Histone Deacetylase (HDAC) Inhibition Assay using Boc-Lys(Ac)-AMC Substrate: Inhibition of HDAC has been implicated to modulate transcription and to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2018
Entry Details Article
PubMed
TargetHistone deacetylase 1/11/4/6/8(Human)
Orchid Chemicals & Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 206284BDBM206284((S)-N1-(1-((4-chlorophenyl)amino)-3-(1H-indol-3-yl...)
Affinity DataIC50: 150nMAssay Description:In brief, 10 μL of HeLa nuclear extract was mixed with various concentrations of target compounds (50 μL), SAHA, using 100% and none HDACs ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2016
Entry Details Article
PubMed
TargetHistone deacetylase 1/11/4/6/8(Human)
Orchid Chemicals & Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 206281BDBM206281((S)-N1-(1-((3-bromophenyl)amino)-3-(1H-indol-3-yl)...)
Affinity DataIC50: 189nMAssay Description:In brief, 10 μL of HeLa nuclear extract was mixed with various concentrations of target compounds (50 μL), SAHA, using 100% and none HDACs ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2016
Entry Details Article
PubMed
TargetHistone deacetylase 1/11/4/6/8(Human)
Orchid Chemicals & Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 206283BDBM206283((S)-N1-(1-((4-fluorophenyl)amino)-3-(1H-indol-3-yl...)
Affinity DataIC50: 202nMAssay Description:In brief, 10 μL of HeLa nuclear extract was mixed with various concentrations of target compounds (50 μL), SAHA, using 100% and none HDACs ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2016
Entry Details Article
PubMed
TargetHistone deacetylase 1/11/4/6/8(Human)
Orchid Chemicals & Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 206278BDBM206278((S)-N1-(3-(1H-indol-3-yl)-1-((naphthalen-1-ylmethy...)
Affinity DataIC50: 225nMAssay Description:In brief, 10 μL of HeLa nuclear extract was mixed with various concentrations of target compounds (50 μL), SAHA, using 100% and none HDACs ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2016
Entry Details Article
PubMed
TargetHistone deacetylase 1/11/4/6/8(Human)
Orchid Chemicals & Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 206267BDBM206267((S)-N1-(3-(1H-indol-3-yl)-1-oxo-1-(propylamino)pro...)
Affinity DataIC50: 227nMAssay Description:In brief, 10 μL of HeLa nuclear extract was mixed with various concentrations of target compounds (50 μL), SAHA, using 100% and none HDACs ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2016
Entry Details Article
PubMed
TargetHistone deacetylase 1/11/4/6/8(Human)
Orchid Chemicals & Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 65483BDBM65483(Quinolone-based HDAC inhibitor 4t)
Affinity DataIC50: 230nMAssay Description:Histone Deacetylase (HDAC) Inhibition Assay using Boc-Lys(Ac)-AMC Substrate: Inhibition of HDAC has been implicated to modulate transcription and to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2018
Entry Details Article
PubMed
TargetHistone deacetylase 1/11/4/6/8(Human)
Orchid Chemicals & Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 206279BDBM206279((S)-N1-(1-((3-fluorophenyl)amino)-3-(1H-indol-3-yl...)
Affinity DataIC50: 234nMAssay Description:In brief, 10 μL of HeLa nuclear extract was mixed with various concentrations of target compounds (50 μL), SAHA, using 100% and none HDACs ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2016
Entry Details Article
PubMed
TargetHistone deacetylase 1/11/4/6/8(Human)
Orchid Chemicals & Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 65459BDBM65459(Quinolone-based HDAC inhibitor 4b)
Affinity DataIC50: 270nMAssay Description:Histone Deacetylase (HDAC) Inhibition Assay using Boc-Lys(Ac)-AMC Substrate: Inhibition of HDAC has been implicated to modulate transcription and to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2018
Entry Details Article
PubMed
TargetHistone deacetylase 1/11/4/6/8(Human)
Orchid Chemicals & Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 206277BDBM206277((S)-N1-(3-(1H-indol-3-yl)-1-oxo-1-(phenethylamino)...)
Affinity DataIC50: 301nMAssay Description:In brief, 10 μL of HeLa nuclear extract was mixed with various concentrations of target compounds (50 μL), SAHA, using 100% and none HDACs ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2016
Entry Details Article
PubMed
TargetHistone deacetylase 1/11/4/6/8(Human)
Orchid Chemicals & Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 65482BDBM65482(Quinolone-based HDAC inhibitor 4s)
Affinity DataIC50: 330nMAssay Description:Histone Deacetylase (HDAC) Inhibition Assay using Boc-Lys(Ac)-AMC Substrate: Inhibition of HDAC has been implicated to modulate transcription and to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2018
Entry Details Article
PubMed
TargetHistone deacetylase 1/11/4/6/8(Human)
Orchid Chemicals & Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 206289BDBM206289((S)-N1-(1-((4-ethoxyphenyl)amino)-3-(1H-indol-3-yl...)
Affinity DataIC50: 335nMAssay Description:In brief, 10 μL of HeLa nuclear extract was mixed with various concentrations of target compounds (50 μL), SAHA, using 100% and none HDACs ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2016
Entry Details Article
PubMed
TargetHistone deacetylase 1/11/4/6/8(Human)
Orchid Chemicals & Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 206276BDBM206276((S)-N1-(1-(benzylamino)-3-(1H-indol-3-yl)-1-oxopro...)
Affinity DataIC50: 346nMAssay Description:In brief, 10 μL of HeLa nuclear extract was mixed with various concentrations of target compounds (50 μL), SAHA, using 100% and none HDACs ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2016
Entry Details Article
PubMed
TargetHistone deacetylase 1/11/4/6/8(Human)
Orchid Chemicals & Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 206280BDBM206280((S)-N1-(1-((3-chlorophenyl)amino)-3-(1H-indol-3-yl...)
Affinity DataIC50: 360nMAssay Description:In brief, 10 μL of HeLa nuclear extract was mixed with various concentrations of target compounds (50 μL), SAHA, using 100% and none HDACs ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2016
Entry Details Article
PubMed
TargetHistone deacetylase 1/11/4/6/8(Human)
Orchid Chemicals & Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 206275BDBM206275((S)-N1-(3-(1H-indol-3-yl)-1-oxo-1-(phenylamino)pro...)
Affinity DataIC50: 361nMAssay Description:In brief, 10 μL of HeLa nuclear extract was mixed with various concentrations of target compounds (50 μL), SAHA, using 100% and none HDACs ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2016
Entry Details Article
PubMed
TargetHistone deacetylase 1/11/4/6/8(Human)
Orchid Chemicals & Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 65467BDBM65467(Quinolone-based HDAC inhibitor 4f)
Affinity DataIC50: 390nMAssay Description:Histone Deacetylase (HDAC) Inhibition Assay using Boc-Lys(Ac)-AMC Substrate: Inhibition of HDAC has been implicated to modulate transcription and to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2018
Entry Details Article
PubMed
TargetHistone deacetylase 1/11/4/6/8(Human)
Orchid Chemicals & Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 65466BDBM65466(Quinolone-based HDAC inhibitor 4e)
Affinity DataIC50: 410nMAssay Description:Histone Deacetylase (HDAC) Inhibition Assay using Boc-Lys(Ac)-AMC Substrate: Inhibition of HDAC has been implicated to modulate transcription and to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2018
Entry Details Article
PubMed
TargetHistone deacetylase 1/11/4/6/8(Human)
Orchid Chemicals & Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 206288BDBM206288((S)-N1-(3-(1H-indol-3-yl)-1-((4-methoxyphenyl)amin...)
Affinity DataIC50: 413nMAssay Description:In brief, 10 μL of HeLa nuclear extract was mixed with various concentrations of target compounds (50 μL), SAHA, using 100% and none HDACs ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2016
Entry Details Article
PubMed
TargetHistone deacetylase 1/11/4/6/8(Human)
Orchid Chemicals & Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 206274BDBM206274((S)-N1-(1-(cyclohexylamino)-3-(1H-indol-3-yl)-1-ox...)
Affinity DataIC50: 416nMAssay Description:In brief, 10 μL of HeLa nuclear extract was mixed with various concentrations of target compounds (50 μL), SAHA, using 100% and none HDACs ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2016
Entry Details Article
PubMed
TargetHistone deacetylase 1/11/4/6/8(Human)
Orchid Chemicals & Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 206282BDBM206282((S)-N1-(3-(1H-indol-3-yl)-1-((3-methoxyphenyl)amin...)
Affinity DataIC50: 435nMAssay Description:In brief, 10 μL of HeLa nuclear extract was mixed with various concentrations of target compounds (50 μL), SAHA, using 100% and none HDACs ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2016
Entry Details Article
PubMed
TargetHistone deacetylase 1/11/4/6/8(Human)
Orchid Chemicals & Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 206272BDBM206272((S)-N1-(1-(tert-butylamino)-3-(1H-indol-3-yl)-1-ox...)
Affinity DataIC50: 504nMAssay Description:In brief, 10 μL of HeLa nuclear extract was mixed with various concentrations of target compounds (50 μL), SAHA, using 100% and none HDACs ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2016
Entry Details Article
PubMed
TargetHistone deacetylase 1/11/4/6/8(Human)
Orchid Chemicals & Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 206271BDBM206271((S)-N1-(3-(1H-indol-3-yl)-1-(isobutylamino)-1-oxop...)
Affinity DataIC50: 527nMAssay Description:In brief, 10 μL of HeLa nuclear extract was mixed with various concentrations of target compounds (50 μL), SAHA, using 100% and none HDACs ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2016
Entry Details Article
PubMed
TargetHistone deacetylase 1/11/4/6/8(Human)
Orchid Chemicals & Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 206273BDBM206273((S)-N1-(1-(cyclopropylamino)-3-(1H-indol-3-yl)-1-o...)
Affinity DataIC50: 683nMAssay Description:In brief, 10 μL of HeLa nuclear extract was mixed with various concentrations of target compounds (50 μL), SAHA, using 100% and none HDACs ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2016
Entry Details Article
PubMed
TargetHistone deacetylase 1/11/4/6/8(Human)
Orchid Chemicals & Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 206290BDBM206290((S)-N1-(3-(1H-indol-3-yl)-1-oxo-1-((4-(trifluorome...)
Affinity DataIC50: 1.29E+3nMAssay Description:In brief, 10 μL of HeLa nuclear extract was mixed with various concentrations of target compounds (50 μL), SAHA, using 100% and none HDACs ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2016
Entry Details Article
PubMed
TargetHistone deacetylase 1/11/4/6/8(Human)
Orchid Chemicals & Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 206268BDBM206268((S)-N1-(3-(1H-indol-3-yl)-1-oxo-1-(propylamino)pro...)
Affinity DataIC50: 1.65E+3nMAssay Description:In brief, 10 μL of HeLa nuclear extract was mixed with various concentrations of target compounds (50 μL), SAHA, using 100% and none HDACs ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2016
Entry Details Article
PubMed
TargetHistone deacetylase 1/11/4/6/8(Human)
Orchid Chemicals & Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 206269BDBM206269((S)-N1-(1-(butylamino)-3-(1H-indol-3-yl)-1-oxoprop...)
Affinity DataIC50: 1.74E+3nMAssay Description:In brief, 10 μL of HeLa nuclear extract was mixed with various concentrations of target compounds (50 μL), SAHA, using 100% and none HDACs ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2016
Entry Details Article
PubMed
TargetHistone deacetylase 1/11/4/6/8(Human)
Orchid Chemicals & Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 206270BDBM206270((S)-N1-(1-(dodecylamino)-3-(1H-indol-3-yl)-1-oxopr...)
Affinity DataIC50: 2.50E+4nMAssay Description:In brief, 10 μL of HeLa nuclear extract was mixed with various concentrations of target compounds (50 μL), SAHA, using 100% and none HDACs ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2016
Entry Details Article
PubMed