Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with Target = 'Integrin alpha-5/alpha-8'
TargetIntegrin alpha-5/alpha-8(Human)
Saint Louis University

US Patent
LigandChemical structure of BindingDB Monomer ID 279573BDBM279573((3S)-3-(3,5-dibromophenyl)-3-[[2-[[5-[(5-hydroxy-1...)
Affinity DataIC50: 0.400nMAssay Description:Recombinant mouse nephronectin protein (R&D Systems, Inc, 4298-NP) diluted to 1 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetIntegrin alpha-5/alpha-8(Human)
Saint Louis University

US Patent
LigandChemical structure of BindingDB Monomer ID 279575BDBM279575((3S)-3-[3-chloro-5-(trifluoromethoxy)phenyl)-3-(2-...)
Affinity DataIC50: 0.5nMAssay Description:Recombinant mouse nephronectin protein (R&D Systems, Inc, 4298-NP) diluted to 1 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetIntegrin alpha-5/alpha-8(Human)
Saint Louis University

US Patent
LigandChemical structure of BindingDB Monomer ID 279568BDBM279568((3S)-3-[3-bromo-5-(trifluoromethyl)phenyl]-3-[[2-[...)
Affinity DataIC50: 0.5nMAssay Description:Recombinant mouse nephronectin protein (R&D Systems, Inc, 4298-NP) diluted to 1 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetIntegrin alpha-5/alpha-8(Human)
Saint Louis University

US Patent
LigandChemical structure of BindingDB Monomer ID 279565BDBM279565((3S)-3-[3-bromo-5-chloro-phenyl)-3-(2-(3-hydroxy-5...)
Affinity DataIC50: 0.5nMAssay Description:Recombinant mouse nephronectin protein (R&D Systems, Inc, 4298-NP) diluted to 1 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetIntegrin alpha-5/alpha-8(Human)
Saint Louis University

US Patent
LigandChemical structure of BindingDB Monomer ID 279563BDBM279563((3S)-3-[3-bromo-5-(difluoromethyl)phenyl)-3-(2-(3-...)
Affinity DataIC50: 0.600nMAssay Description:Recombinant mouse nephronectin protein (R&D Systems, Inc, 4298-NP) diluted to 1 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetIntegrin alpha-5/alpha-8(Human)
Saint Louis University

US Patent
LigandChemical structure of BindingDB Monomer ID 279572BDBM279572((3S)-3-[3-bromo-5-fluoro-phenyl)-3-(2-(3-hydroxy-5...)
Affinity DataIC50: 0.600nMAssay Description:Recombinant mouse nephronectin protein (R&D Systems, Inc, 4298-NP) diluted to 1 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetIntegrin alpha-5/alpha-8(Human)
Saint Louis University

US Patent
LigandChemical structure of BindingDB Monomer ID 279567BDBM279567((3S)-3-(3-bromo-5-chloro-phenyl)-3-[[2-[[5-[(5-hyd...)
Affinity DataIC50: 0.600nMAssay Description:Recombinant mouse nephronectin protein (R&D Systems, Inc, 4298-NP) diluted to 1 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetIntegrin alpha-5/alpha-8(Human)
Saint Louis University

US Patent
LigandChemical structure of BindingDB Monomer ID 279566BDBM279566((3S)-3-[3-chloro-5-(trifluoromethyl)phenyl]3-[[2-[...)
Affinity DataIC50: 0.600nMAssay Description:Recombinant mouse nephronectin protein (R&D Systems, Inc, 4298-NP) diluted to 1 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetIntegrin alpha-5/alpha-8(Human)
Saint Louis University

US Patent
LigandChemical structure of BindingDB Monomer ID 279570BDBM279570((3S)-3-[3-bromo-5-methyl-phenyl)-3-(2-(3-hydroxy-5...)
Affinity DataIC50: 0.700nMAssay Description:Recombinant mouse nephronectin protein (R&D Systems, Inc, 4298-NP) diluted to 1 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetIntegrin alpha-5/alpha-8(Human)
Saint Louis University

US Patent
LigandChemical structure of BindingDB Monomer ID 279576BDBM279576((3S)-3-(3-bromo-5-(trifluoromethoxy)phenyl)-3-(2-(...)
Affinity DataIC50: 0.700nMAssay Description:Recombinant mouse nephronectin protein (R&D Systems, Inc, 4298-NP) diluted to 1 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetIntegrin alpha-5/alpha-8(Human)
Saint Louis University

US Patent
LigandChemical structure of BindingDB Monomer ID 279571BDBM279571((3S)-3-[3-chloro-5-methyl-phenyl)-3-(2-(3-hydroxy-...)
Affinity DataIC50: 0.800nMAssay Description:Recombinant mouse nephronectin protein (R&D Systems, Inc, 4298-NP) diluted to 1 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetIntegrin alpha-5/alpha-8(Human)
Saint Louis University

US Patent
LigandChemical structure of BindingDB Monomer ID 279562BDBM279562((3S)-3-[3-chloro-5-(difluoromethyl)phenyl)-3-(2-(3...)
Affinity DataIC50: 0.900nMAssay Description:Recombinant mouse nephronectin protein (R&D Systems, Inc, 4298-NP) diluted to 1 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetIntegrin alpha-5/alpha-8(Human)
Saint Louis University

US Patent
LigandChemical structure of BindingDB Monomer ID 279564BDBM279564((3S)-3-[3-chloro-5-(trifluoromethyl)phenyl)-3-(2-(...)
Affinity DataIC50: 0.900nMAssay Description:Recombinant mouse nephronectin protein (R&D Systems, Inc, 4298-NP) diluted to 1 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetIntegrin alpha-5/alpha-8(Human)
Saint Louis University

US Patent
LigandChemical structure of BindingDB Monomer ID 279569BDBM279569((3S)-3-[3,5-bis(trifluoromethyl)phenyl)-3-(2-(3-hy...)
Affinity DataIC50: 1.10nMAssay Description:Recombinant mouse nephronectin protein (R&D Systems, Inc, 4298-NP) diluted to 1 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetIntegrin alpha-5/alpha-8(Human)
Saint Louis University

US Patent
LigandChemical structure of BindingDB Monomer ID 279574BDBM279574((3S)-3-[3,5-dichloro-phenyl)-3-(2-(3-hydroxy-5-((5...)
Affinity DataIC50: 1.20nMAssay Description:Recombinant mouse nephronectin protein (R&D Systems, Inc, 4298-NP) diluted to 1 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetIntegrin alpha-5/alpha-8(Human)
Saint Louis University

US Patent
LigandChemical structure of BindingDB Monomer ID 279560BDBM279560((3S)-3-(3,5-dibromophenyl)-3-(2-(3-hydroxy-5-((5-h...)
Affinity DataIC50: 1.30nMAssay Description:Recombinant mouse nephronectin protein (R&D Systems, Inc, 4298-NP) diluted to 1 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetIntegrin alpha-5/alpha-8(Human)
Saint Louis University

US Patent
LigandChemical structure of BindingDB Monomer ID 279561BDBM279561((3S)-3-(3-bromo-5-(trifluoromethyl)phenyl)-3-(2-(3...)
Affinity DataIC50: 1.5nMAssay Description:Recombinant mouse nephronectin protein (R&D Systems, Inc, 4298-NP) diluted to 1 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetIntegrin alpha-5/alpha-8(Human)
Saint Louis University

US Patent
LigandChemical structure of BindingDB Monomer ID 432093BDBM432093(US10577330, Comparison Compound C2)
Affinity DataIC50: 3nMAssay Description:Recombinant mouse nephronectin protein (R&D Systems, Inc, 4298-NP) diluted to 1 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetIntegrin alpha-5/alpha-8(Human)
Saint Louis University

US Patent
LigandChemical structure of BindingDB Monomer ID 432092BDBM432092(US10577330, Comparison Compound C1)
Affinity DataIC50: 8nMAssay Description:Recombinant mouse nephronectin protein (R&D Systems, Inc, 4298-NP) diluted to 1 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetIntegrin alpha-5/alpha-8(Human)
Saint Louis University

US Patent
LigandChemical structure of BindingDB Monomer ID 432101BDBM432101(US10577330, Comparison Compound C10)
Affinity DataIC50: 10nMAssay Description:Recombinant mouse nephronectin protein (R&D Systems, Inc, 4298-NP) diluted to 1 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetIntegrin alpha-5/alpha-8(Human)
Saint Louis University

US Patent
LigandChemical structure of BindingDB Monomer ID 432094BDBM432094(US10577330, Comparison Compound C3)
Affinity DataIC50: 14nMAssay Description:Recombinant mouse nephronectin protein (R&D Systems, Inc, 4298-NP) diluted to 1 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetIntegrin alpha-5/alpha-8(Human)
Saint Louis University

US Patent
LigandChemical structure of BindingDB Monomer ID 432097BDBM432097(US10577330, Comparison Compound C6)
Affinity DataIC50: 17nMAssay Description:Recombinant mouse nephronectin protein (R&D Systems, Inc, 4298-NP) diluted to 1 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetIntegrin alpha-5/alpha-8(Human)
Saint Louis University

US Patent
LigandChemical structure of BindingDB Monomer ID 432102BDBM432102(US10577330, Comparison Compound C11)
Affinity DataIC50: 17nMAssay Description:Recombinant mouse nephronectin protein (R&D Systems, Inc, 4298-NP) diluted to 1 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetIntegrin alpha-5/alpha-8(Human)
Saint Louis University

US Patent
LigandChemical structure of BindingDB Monomer ID 432098BDBM432098(US10577330, Comparison Compound C7)
Affinity DataIC50: 26nMAssay Description:Recombinant mouse nephronectin protein (R&D Systems, Inc, 4298-NP) diluted to 1 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetIntegrin alpha-5/alpha-8(Human)
Saint Louis University

US Patent
LigandChemical structure of BindingDB Monomer ID 432100BDBM432100(US10577330, Comparison Compound C9)
Affinity DataIC50: 40nMAssay Description:Recombinant mouse nephronectin protein (R&D Systems, Inc, 4298-NP) diluted to 1 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetIntegrin alpha-5/alpha-8(Human)
Saint Louis University

US Patent
LigandChemical structure of BindingDB Monomer ID 432095BDBM432095(US10577330, Comparison Compound C4)
Affinity DataIC50: 63nMAssay Description:Recombinant mouse nephronectin protein (R&D Systems, Inc, 4298-NP) diluted to 1 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetIntegrin alpha-5/alpha-8(Human)
Saint Louis University

US Patent
LigandChemical structure of BindingDB Monomer ID 432096BDBM432096(US10577330, Comparison Compound C5)
Affinity DataIC50: 383nMAssay Description:Recombinant mouse nephronectin protein (R&D Systems, Inc, 4298-NP) diluted to 1 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetIntegrin alpha-5/alpha-8(Human)
Saint Louis University

US Patent
LigandChemical structure of BindingDB Monomer ID 432099BDBM432099(US10577330, Comparison Compound C8)
Affinity DataIC50: 594nMAssay Description:Recombinant mouse nephronectin protein (R&D Systems, Inc, 4298-NP) diluted to 1 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent