Compile Data Set for Download or QSAR
Report error Found 594 Enz. Inhib. hit(s) with Target = 'Integrin alpha-V/beta-5'
TargetIntegrin alpha-V/beta-5(Human)
Saint Louis University

US Patent
LigandChemical structure of BindingDB Monomer ID 279572BDBM279572((3S)-3-[3-bromo-5-fluoro-phenyl)-3-(2-(3-hydroxy-5...)
Affinity DataIC50: 0.100nMAssay Description:Recombinant human vitronectin (R& D Systems, 2308-VN) at 0.25 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetIntegrin alpha-V/beta-5(Human)
Saint Louis University

US Patent
LigandChemical structure of BindingDB Monomer ID 279573BDBM279573((3S)-3-(3,5-dibromophenyl)-3-[[2-[[5-[(5-hydroxy-1...)
Affinity DataIC50: 0.100nMpH: 7.4 T: 2°CAssay Description:Recombinant human vitronectin (R&D Systems, 2308-VN) at 0.25 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2018
Entry Details
US Patent

TargetIntegrin alpha-V/beta-5(Human)
Saint Louis University

US Patent
LigandChemical structure of BindingDB Monomer ID 279567BDBM279567((3S)-3-(3-bromo-5-chloro-phenyl)-3-[[2-[[5-[(5-hyd...)
Affinity DataIC50: 0.100nMAssay Description:Recombinant human vitronectin (R& D Systems, 2308-VN) at 0.25 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetIntegrin alpha-V/beta-5(Human)
Saint Louis University

US Patent
LigandChemical structure of BindingDB Monomer ID 279573BDBM279573((3S)-3-(3,5-dibromophenyl)-3-[[2-[[5-[(5-hydroxy-1...)
Affinity DataIC50: 0.100nMAssay Description:Recombinant human vitronectin (R& D Systems, 2308-VN) at 0.25 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetIntegrin alpha-V/beta-5(Human)
Saint Louis University

US Patent
LigandChemical structure of BindingDB Monomer ID 50120519BDBM50120519((7-{[4-(1,4,5,6-Tetrahydro-pyrimidin-2-ylamino)-bu...)
Affinity DataIC50: 0.100nMAssay Description:Displacement of vitronectin from human integrin alphaV-beta5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-5(Human)
Saint Louis University

US Patent
LigandChemical structure of BindingDB Monomer ID 279567BDBM279567((3S)-3-(3-bromo-5-chloro-phenyl)-3-[[2-[[5-[(5-hyd...)
Affinity DataIC50: 0.100nMpH: 7.4 T: 2°CAssay Description:Recombinant human vitronectin (R&D Systems, 2308-VN) at 0.25 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2018
Entry Details
US Patent

TargetIntegrin alpha-V/beta-5(Human)
Saint Louis University

US Patent
LigandChemical structure of BindingDB Monomer ID 279572BDBM279572((3S)-3-[3-bromo-5-fluoro-phenyl)-3-(2-(3-hydroxy-5...)
Affinity DataIC50: 0.100nMpH: 7.4 T: 2°CAssay Description:Recombinant human vitronectin (R&D Systems, 2308-VN) at 0.25 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2018
Entry Details
US Patent

TargetIntegrin alpha-V/beta-5(Human)
Saint Louis University

US Patent
LigandChemical structure of BindingDB Monomer ID 50237601BDBM50237601([5-Benzyl-11-(3-guanidino-propyl)-8-isopropyl-3,6,...)
Affinity DataIC50: 0.110nMAssay Description:Displacement of [125I]-echistatin from alpha-v-beta-5 integrin receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-5(Human)
Saint Louis University

US Patent
LigandChemical structure of BindingDB Monomer ID 50237601BDBM50237601([5-Benzyl-11-(3-guanidino-propyl)-8-isopropyl-3,6,...)
Affinity DataIC50: 0.110nMAssay Description:Displacement of [125I]Echistatin from human placental integrin alpha-V-beta-5 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-5(Human)
Saint Louis University

US Patent
LigandChemical structure of BindingDB Monomer ID 50237601BDBM50237601([5-Benzyl-11-(3-guanidino-propyl)-8-isopropyl-3,6,...)
Affinity DataIC50: 0.110nMAssay Description:Displacement of [125I]echistatin from AlphaV-beta-5 integrin receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-5(Human)
Saint Louis University

US Patent
LigandChemical structure of BindingDB Monomer ID 50235980BDBM50235980(CHEMBL429876 | EMD-121974 | cyclo(Arg-Gly-Asp-D-Ph...)
Affinity DataIC50: 0.130nMAssay Description:Displacement of [125I]Echistatin from human placental integrin alpha-V-beta-5 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-5(Human)
Saint Louis University

US Patent
LigandChemical structure of BindingDB Monomer ID 50235980BDBM50235980(CHEMBL429876 | EMD-121974 | cyclo(Arg-Gly-Asp-D-Ph...)
Affinity DataIC50: 0.130nMAssay Description:Displacement of [125I]-echistatin from alpha-v-beta-5 integrin receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-5(Human)
Saint Louis University

US Patent
LigandChemical structure of BindingDB Monomer ID 50235980BDBM50235980(CHEMBL429876 | EMD-121974 | cyclo(Arg-Gly-Asp-D-Ph...)
Affinity DataIC50: 0.130nMAssay Description:Displacement of [125I]echistatin from AlphaV-beta-5 integrin receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-5(Human)
Saint Louis University

US Patent
LigandChemical structure of BindingDB Monomer ID 50235980BDBM50235980(CHEMBL429876 | EMD-121974 | cyclo(Arg-Gly-Asp-D-Ph...)
Affinity DataIC50: 0.130nMAssay Description:Displacement of [125I]echistatin from human integrin alpha-V-beta-5 receptor by solid phase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-5(Human)
Saint Louis University

US Patent
LigandChemical structure of BindingDB Monomer ID 50308730BDBM50308730(4-((2S,5S,11S,14R)-14-benzyl-11-(carboxymethyl)-5-...)
Affinity DataIC50: 0.170nMAssay Description:Displacement of [125I]echistatin from integrin alphaVbeta5 receptor after 3 hrs by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-5(Human)
Saint Louis University

US Patent
LigandChemical structure of BindingDB Monomer ID 279565BDBM279565((3S)-3-[3-bromo-5-chloro-phenyl)-3-(2-(3-hydroxy-5...)
Affinity DataIC50: 0.200nMAssay Description:Recombinant human vitronectin (R& D Systems, 2308-VN) at 0.25 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetIntegrin alpha-V/beta-5(Human)
Saint Louis University

US Patent
LigandChemical structure of BindingDB Monomer ID 279566BDBM279566((3S)-3-[3-chloro-5-(trifluoromethyl)phenyl]3-[[2-[...)
Affinity DataIC50: 0.200nMpH: 7.4 T: 2°CAssay Description:Recombinant human vitronectin (R&D Systems, 2308-VN) at 0.25 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2018
Entry Details
US Patent

TargetIntegrin alpha-V/beta-5(Human)
Saint Louis University

US Patent
LigandChemical structure of BindingDB Monomer ID 279560BDBM279560((3S)-3-(3,5-dibromophenyl)-3-(2-(3-hydroxy-5-((5-h...)
Affinity DataIC50: 0.200nMAssay Description:Recombinant human vitronectin (R& D Systems, 2308-VN) at 0.25 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetIntegrin alpha-V/beta-5(Human)
Saint Louis University

US Patent
LigandChemical structure of BindingDB Monomer ID 279562BDBM279562((3S)-3-[3-chloro-5-(difluoromethyl)phenyl)-3-(2-(3...)
Affinity DataIC50: 0.200nMpH: 7.4 T: 2°CAssay Description:Recombinant human vitronectin (R&D Systems, 2308-VN) at 0.25 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2018
Entry Details
US Patent

TargetIntegrin alpha-V/beta-5(Human)
Saint Louis University

US Patent
LigandChemical structure of BindingDB Monomer ID 279560BDBM279560((3S)-3-(3,5-dibromophenyl)-3-(2-(3-hydroxy-5-((5-h...)
Affinity DataIC50: 0.200nMpH: 7.4 T: 2°CAssay Description:Recombinant human vitronectin (R&D Systems, 2308-VN) at 0.25 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2018
Entry Details
US Patent

TargetIntegrin alpha-V/beta-5(Human)
Saint Louis University

US Patent
LigandChemical structure of BindingDB Monomer ID 279562BDBM279562((3S)-3-[3-chloro-5-(difluoromethyl)phenyl)-3-(2-(3...)
Affinity DataIC50: 0.200nMAssay Description:Recombinant human vitronectin (R& D Systems, 2308-VN) at 0.25 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetIntegrin alpha-V/beta-5(Human)
Saint Louis University

US Patent
LigandChemical structure of BindingDB Monomer ID 279565BDBM279565((3S)-3-[3-bromo-5-chloro-phenyl)-3-(2-(3-hydroxy-5...)
Affinity DataIC50: 0.200nMpH: 7.4 T: 2°CAssay Description:Recombinant human vitronectin (R&D Systems, 2308-VN) at 0.25 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2018
Entry Details
US Patent

TargetIntegrin alpha-V/beta-5(Human)
Saint Louis University

US Patent
LigandChemical structure of BindingDB Monomer ID 50120520BDBM50120520((7-{[4-(4,5-Dihydro-1H-imidazol-2-ylamino)-butyryl...)
Affinity DataIC50: 0.200nMAssay Description:Displacement of vitronectin from human integrin alphaV-beta5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-5(Human)
Saint Louis University

US Patent
LigandChemical structure of BindingDB Monomer ID 279566BDBM279566((3S)-3-[3-chloro-5-(trifluoromethyl)phenyl]3-[[2-[...)
Affinity DataIC50: 0.200nMAssay Description:Recombinant human vitronectin (R& D Systems, 2308-VN) at 0.25 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetIntegrin alpha-V/beta-5(Human)
Saint Louis University

US Patent
LigandChemical structure of BindingDB Monomer ID 50166693BDBM50166693(3-Pyridin-3-yl-3-{5-[2-(5,6,7,8-tetrahydro-[1,8]na...)
Affinity DataIC50: 0.210nMAssay Description:Binding affinity to Integrin alpha-v-beta-5 receptor by ELISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-5(Human)
Saint Louis University

US Patent
LigandChemical structure of BindingDB Monomer ID 279570BDBM279570((3S)-3-[3-bromo-5-methyl-phenyl)-3-(2-(3-hydroxy-5...)
Affinity DataIC50: 0.300nMpH: 7.4 T: 2°CAssay Description:Recombinant human vitronectin (R&D Systems, 2308-VN) at 0.25 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2018
Entry Details
US Patent

TargetIntegrin alpha-V/beta-5(Human)
Saint Louis University

US Patent
LigandChemical structure of BindingDB Monomer ID 279568BDBM279568((3S)-3-[3-bromo-5-(trifluoromethyl)phenyl]-3-[[2-[...)
Affinity DataIC50: 0.300nMpH: 7.4 T: 2°CAssay Description:Recombinant human vitronectin (R&D Systems, 2308-VN) at 0.25 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2018
Entry Details
US Patent

TargetIntegrin alpha-V/beta-5(Human)
Saint Louis University

US Patent
LigandChemical structure of BindingDB Monomer ID 279570BDBM279570((3S)-3-[3-bromo-5-methyl-phenyl)-3-(2-(3-hydroxy-5...)
Affinity DataIC50: 0.300nMAssay Description:Recombinant human vitronectin (R& D Systems, 2308-VN) at 0.25 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetIntegrin alpha-V/beta-5(Human)
Saint Louis University

US Patent
LigandChemical structure of BindingDB Monomer ID 279574BDBM279574((3S)-3-[3,5-dichloro-phenyl)-3-(2-(3-hydroxy-5-((5...)
Affinity DataIC50: 0.300nMAssay Description:Recombinant human vitronectin (R& D Systems, 2308-VN) at 0.25 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetIntegrin alpha-V/beta-5(Human)
Saint Louis University

US Patent
LigandChemical structure of BindingDB Monomer ID 279574BDBM279574((3S)-3-[3,5-dichloro-phenyl)-3-(2-(3-hydroxy-5-((5...)
Affinity DataIC50: 0.300nMpH: 7.4 T: 2°CAssay Description:Recombinant human vitronectin (R&D Systems, 2308-VN) at 0.25 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2018
Entry Details
US Patent

TargetIntegrin alpha-V/beta-5(Human)
Saint Louis University

US Patent
LigandChemical structure of BindingDB Monomer ID 279568BDBM279568((3S)-3-[3-bromo-5-(trifluoromethyl)phenyl]-3-[[2-[...)
Affinity DataIC50: 0.300nMAssay Description:Recombinant human vitronectin (R& D Systems, 2308-VN) at 0.25 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetIntegrin alpha-V/beta-5(Human)
Saint Louis University

US Patent
LigandChemical structure of BindingDB Monomer ID 50120517BDBM50120517({7-[(4-5,6,7,8-Tetrahydro-[1,8]naphthyridin-2-yl-b...)
Affinity DataIC50: 0.300nMAssay Description:Displacement of vitronectin from human integrin alphaV-beta5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-5(Human)
Saint Louis University

US Patent
LigandChemical structure of BindingDB Monomer ID 50308728BDBM50308728(1-(4-((5S,11S,14R)-14-benzyl-11-(carboxymethyl)-5-...)
Affinity DataIC50: 0.350nMAssay Description:Displacement of [125I]echistatin from integrin alphaVbeta5 receptor after 3 hrs by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-5(Human)
Saint Louis University

US Patent
LigandChemical structure of BindingDB Monomer ID 50308726BDBM50308726(2-[(2S,5R,8S,11S)-5-benzyl-11-(3-carbamimidamidopr...)
Affinity DataIC50: 0.370nMAssay Description:Displacement of [125I]echistatin from integrin alphaVbeta5 receptor after 3 hrs by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-5(Human)
Saint Louis University

US Patent
LigandChemical structure of BindingDB Monomer ID 50141355BDBM50141355(3-[4-(3-Guanidino-benzoylamino)-2-methoxy-phenyl]-...)
Affinity DataIC50: 0.380nMAssay Description:Binding affinity towards alpha V-beta5 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-5(Human)
Saint Louis University

US Patent
LigandChemical structure of BindingDB Monomer ID 279561BDBM279561((3S)-3-(3-bromo-5-(trifluoromethyl)phenyl)-3-(2-(3...)
Affinity DataIC50: 0.400nMpH: 7.4 T: 2°CAssay Description:Recombinant human vitronectin (R&D Systems, 2308-VN) at 0.25 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2018
Entry Details
US Patent

TargetIntegrin alpha-V/beta-5(Human)
Saint Louis University

US Patent
LigandChemical structure of BindingDB Monomer ID 279563BDBM279563((3S)-3-[3-bromo-5-(difluoromethyl)phenyl)-3-(2-(3-...)
Affinity DataIC50: 0.400nMAssay Description:Recombinant human vitronectin (R& D Systems, 2308-VN) at 0.25 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetIntegrin alpha-V/beta-5(Human)
Saint Louis University

US Patent
LigandChemical structure of BindingDB Monomer ID 279571BDBM279571((3S)-3-[3-chloro-5-methyl-phenyl)-3-(2-(3-hydroxy-...)
Affinity DataIC50: 0.400nMpH: 7.4 T: 2°CAssay Description:Recombinant human vitronectin (R&D Systems, 2308-VN) at 0.25 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2018
Entry Details
US Patent

TargetIntegrin alpha-V/beta-5(Human)
Saint Louis University

US Patent
LigandChemical structure of BindingDB Monomer ID 432100BDBM432100(US10577330, Comparison Compound C9)
Affinity DataIC50: 0.400nMAssay Description:Recombinant human vitronectin (R& D Systems, 2308-VN) at 0.25 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetIntegrin alpha-V/beta-5(Human)
Saint Louis University

US Patent
LigandChemical structure of BindingDB Monomer ID 279571BDBM279571((3S)-3-[3-chloro-5-methyl-phenyl)-3-(2-(3-hydroxy-...)
Affinity DataIC50: 0.400nMAssay Description:Recombinant human vitronectin (R& D Systems, 2308-VN) at 0.25 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetIntegrin alpha-V/beta-5(Human)
Saint Louis University

US Patent
LigandChemical structure of BindingDB Monomer ID 279561BDBM279561((3S)-3-(3-bromo-5-(trifluoromethyl)phenyl)-3-(2-(3...)
Affinity DataIC50: 0.400nMAssay Description:Recombinant human vitronectin (R& D Systems, 2308-VN) at 0.25 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetIntegrin alpha-V/beta-5(Human)
Saint Louis University

US Patent
LigandChemical structure of BindingDB Monomer ID 432093BDBM432093(US10577330, Comparison Compound C2)
Affinity DataIC50: 0.400nMAssay Description:Recombinant human vitronectin (R& D Systems, 2308-VN) at 0.25 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetIntegrin alpha-V/beta-5(Human)
Saint Louis University

US Patent
LigandChemical structure of BindingDB Monomer ID 279563BDBM279563((3S)-3-[3-bromo-5-(difluoromethyl)phenyl)-3-(2-(3-...)
Affinity DataIC50: 0.400nMpH: 7.4 T: 2°CAssay Description:Recombinant human vitronectin (R&D Systems, 2308-VN) at 0.25 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2018
Entry Details
US Patent

TargetIntegrin alpha-V/beta-5(Human)
Saint Louis University

US Patent
LigandChemical structure of BindingDB Monomer ID 50141324BDBM50141324(2-Isopropoxycarbonylamino-3-{2-methoxy-4-[3-(1,4,5...)
Affinity DataIC50: 0.410nMAssay Description:Binding affinity towards alpha V-beta5 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-5(Human)
Saint Louis University

US Patent
LigandChemical structure of BindingDB Monomer ID 50120523BDBM50120523((7-{[4-(1H-Benzoimidazol-2-ylamino)-butyrylamino]-...)
Affinity DataIC50: 0.5nMAssay Description:Displacement of vitronectin from human integrin alphaV-beta5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-5(Human)
Saint Louis University

US Patent
LigandChemical structure of BindingDB Monomer ID 279564BDBM279564((3S)-3-[3-chloro-5-(trifluoromethyl)phenyl)-3-(2-(...)
Affinity DataIC50: 0.5nMpH: 7.4 T: 2°CAssay Description:Recombinant human vitronectin (R&D Systems, 2308-VN) at 0.25 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2018
Entry Details
US Patent

TargetIntegrin alpha-V/beta-5(Human)
Saint Louis University

US Patent
LigandChemical structure of BindingDB Monomer ID 50166678BDBM50166678(3-Benzo[1,3]dioxol-5-yl-3-{5-[2-(5,6,7,8-tetrahydr...)
Affinity DataIC50: 0.5nMAssay Description:Binding affinity to Integrin alpha-v-beta-5 receptor by ELISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-5(Human)
Saint Louis University

US Patent
LigandChemical structure of BindingDB Monomer ID 279564BDBM279564((3S)-3-[3-chloro-5-(trifluoromethyl)phenyl)-3-(2-(...)
Affinity DataIC50: 0.5nMAssay Description:Recombinant human vitronectin (R& D Systems, 2308-VN) at 0.25 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
US Patent

TargetIntegrin alpha-V/beta-5(Human)
Saint Louis University

US Patent
LigandChemical structure of BindingDB Monomer ID 50177887BDBM50177887(CHEMBL269913 | CHEMBL556402 | c-[-Arg-Gly-Asp-Acpc...)
Affinity DataIC50: 0.590nMAssay Description:Displacement of [125I]-echistatin from alpha-v-beta-5 integrin receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-5(Human)
Saint Louis University

US Patent
LigandChemical structure of BindingDB Monomer ID 279575BDBM279575((3S)-3-[3-chloro-5-(trifluoromethoxy)phenyl)-3-(2-...)
Affinity DataIC50: 0.600nMpH: 7.4 T: 2°CAssay Description:Recombinant human vitronectin (R&D Systems, 2308-VN) at 0.25 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2018
Entry Details
US Patent

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