Compile Data Set for Download or QSAR
Report error Found 526 Enz. Inhib. hit(s) with Target = 'Interleukin-17 receptor A/'
TargetInterleukin-17 receptor A/(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 740381BDBM740381(5-cyano-N-((1S)-1- cyclohexyl-2-((2- (methylcarbam...)
Affinity DataIC50: 5.5nMAssay Description:Compounds disclosed herein were tested for blocking of human IL-17A (Cat: C774, novoprotein) protein with its receptor human IL-17RA (Cat: C153, novo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetInterleukin-17 receptor A/(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 740369BDBM740369(N-(1-(4- ethylcyclohexyl)-2-((2- (methylcarbamoyl)...)
Affinity DataIC50: 5.60nMAssay Description:Compounds disclosed herein were tested for blocking of human IL-17A (Cat: C774, novoprotein) protein with its receptor human IL-17RA (Cat: C153, novo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetInterleukin-17 receptor A/(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 740335BDBM740335(N-((1S)-1-cyclohexyl- 2-((2- (methylcarbamoyl)-2- ...)
Affinity DataIC50: 5.80nMAssay Description:Compounds disclosed herein were tested for blocking of human IL-17A (Cat: C774, novoprotein) protein with its receptor human IL-17RA (Cat: C153, novo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetInterleukin-17 receptor A/(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 548167BDBM548167(WO2022091056, Example 158)
Affinity DataIC50: 6.10nMAssay Description: Dilutions of test compounds in DMSO are plated onto white low-volume 384-well plates (Greiner, #784075). Specifically, solutions of graded concentra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2022
Entry Details
WIPO WO2022091056

TargetInterleukin-17 receptor A/(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 740198BDBM740198(N-(1-(6-chloro-1,2,3,4- tetrahydronaphthalen-2- yl...)
Affinity DataIC50: 6.30nMAssay Description:Compounds disclosed herein were tested for blocking of human IL-17A (Cat: C774, novoprotein) protein with its receptor human IL-17RA (Cat: C153, novo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetInterleukin-17 receptor A/(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 740228BDBM740228(N-(1-(5-chloro-1,2,3,4- tetrahydronaphthalen-2- yl...)
Affinity DataIC50: 6.5nMAssay Description:Compounds disclosed herein were tested for blocking of human IL-17A (Cat: C774, novoprotein) protein with its receptor human IL-17RA (Cat: C153, novo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetInterleukin-17 receptor A/(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 740169BDBM740169(N-((1S)-1-((1r,4S)-4- ethylcyclohexyl)-2-((2- (met...)
Affinity DataIC50: 7nMAssay Description:Compounds disclosed herein were tested for blocking of human IL-17A (Cat: C774, novoprotein) protein with its receptor human IL-17RA (Cat: C153, novo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetInterleukin-17 receptor A/(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 740323BDBM740323(N-(1-(4- ethylcyclohexyl)-2-((2- ((R)-4-isopropyl-...)
Affinity DataIC50: 7.5nMAssay Description:Compounds disclosed herein were tested for blocking of human IL-17A (Cat: C774, novoprotein) protein with its receptor human IL-17RA (Cat: C153, novo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetInterleukin-17 receptor A/(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 548005BDBM548005(2,4-dimethyl-3-(4-((S)-2-(1-methyl-1H-pyrazole-5-c...)
Affinity DataIC50: 8nMAssay Description: Dilutions of test compounds in DMSO are plated onto white low-volume 384-well plates (Greiner, #784075). Specifically, solutions of graded concentra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2022
Entry Details
WIPO WO2022091056

TargetInterleukin-17 receptor A/(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 740325BDBM740325(N-((1S)-1-cyclohexyl- 2-((2- (methylcarbamoyl)-2- ...)
Affinity DataIC50: 9.5nMAssay Description:Compounds disclosed herein were tested for blocking of human IL-17A (Cat: C774, novoprotein) protein with its receptor human IL-17RA (Cat: C153, novo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetInterleukin-17 receptor A/(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 740131BDBM740131(N-(1-(4- isopropylcyclohexyl)-2- ((2-(methylcarbam...)
Affinity DataIC50: 10nMAssay Description:Compounds disclosed herein were tested for blocking of human IL-17A (Cat: C774, novoprotein) protein with its receptor human IL-17RA (Cat: C153, novo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetInterleukin-17 receptor A/(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 740397BDBM740397(N-(1-(4- ethylcyclohexyl)-2-((2- (methylcarbamoyl)...)
Affinity DataIC50: 10nMAssay Description:Compounds disclosed herein were tested for blocking of human IL-17A (Cat: C774, novoprotein) protein with its receptor human IL-17RA (Cat: C153, novo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetInterleukin-17 receptor A/(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 740363BDBM740363(N-((1S)-1-cyclohexyl- 2-((2-(((R)-1- cyclohexyl-2-...)
Affinity DataIC50: 10nMAssay Description:Compounds disclosed herein were tested for blocking of human IL-17A (Cat: C774, novoprotein) protein with its receptor human IL-17RA (Cat: C153, novo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetInterleukin-17 receptor A/(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 740184BDBM740184(N-((1S)-1-cyclohexyl-2- ((2-(5-methyl-2-oxo-5- (tr...)
Affinity DataIC50: 10.9nMAssay Description:Compounds disclosed herein were tested for blocking of human IL-17A (Cat: C774, novoprotein) protein with its receptor human IL-17RA (Cat: C153, novo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetInterleukin-17 receptor A/(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 740215BDBM740215(N-((1S)-1-cycloheptyl- 2-((2-((R)-4-isopropyl- 2-o...)
Affinity DataIC50: 11nMAssay Description:Compounds disclosed herein were tested for blocking of human IL-17A (Cat: C774, novoprotein) protein with its receptor human IL-17RA (Cat: C153, novo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetInterleukin-17 receptor A/(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 740328BDBM740328(N-(2-((2-((R)-4- isopropyl-2- oxoimidazolidin-1-yl...)
Affinity DataIC50: 12nMAssay Description:Compounds disclosed herein were tested for blocking of human IL-17A (Cat: C774, novoprotein) protein with its receptor human IL-17RA (Cat: C153, novo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetInterleukin-17 receptor A/(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 548056BDBM548056(WO2022091056, Example 48)
Affinity DataIC50: 12nMAssay Description: Dilutions of test compounds in DMSO are plated onto white low-volume 384-well plates (Greiner, #784075). Specifically, solutions of graded concentra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2022
Entry Details
WIPO WO2022091056

TargetInterleukin-17 receptor A/(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 548188BDBM548188(WO2022091056, Example 196 | WO2022091056, Example ...)
Affinity DataIC50: 14nMAssay Description: Dilutions of test compounds in DMSO are plated onto white low-volume 384-well plates (Greiner, #784075). Specifically, solutions of graded concentra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2022
Entry Details
WIPO WO2022091056

TargetInterleukin-17 receptor A/(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 548093BDBM548093(WO2022091056, Example 84)
Affinity DataIC50: 14nMAssay Description: Dilutions of test compounds in DMSO are plated onto white low-volume 384-well plates (Greiner, #784075). Specifically, solutions of graded concentra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2022
Entry Details
WIPO WO2022091056

TargetInterleukin-17 receptor A/(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 548071BDBM548071(WO2022091056, Example 62)
Affinity DataIC50: 15nMAssay Description: Dilutions of test compounds in DMSO are plated onto white low-volume 384-well plates (Greiner, #784075). Specifically, solutions of graded concentra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2022
Entry Details
WIPO WO2022091056

TargetInterleukin-17 receptor A/(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 740339BDBM740339(N-((1S)-1-cyclohexyl- 2-((2- (methylcarbamoyl)-2- ...)
Affinity DataIC50: 15nMAssay Description:Compounds disclosed herein were tested for blocking of human IL-17A (Cat: C774, novoprotein) protein with its receptor human IL-17RA (Cat: C153, novo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetInterleukin-17 receptor A/(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 740329BDBM740329(N-((1S)-1-cyclohexyl- 2-((2-(5-ethyl-5-methyl- 2- ...)
Affinity DataIC50: 15nMAssay Description:Compounds disclosed herein were tested for blocking of human IL-17A (Cat: C774, novoprotein) protein with its receptor human IL-17RA (Cat: C153, novo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetInterleukin-17 receptor A/(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 740204BDBM740204(5-((S)-2-cyclohexyl-2- (1-methyl-1H-pyrazole- 5- c...)
Affinity DataIC50: 15.3nMAssay Description:Compounds disclosed herein were tested for blocking of human IL-17A (Cat: C774, novoprotein) protein with its receptor human IL-17RA (Cat: C153, novo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetInterleukin-17 receptor A/(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 740282BDBM740282(N-((1S)-1-(4,4- difluorocyclohexyl)-2- oxo-2-((2-(...)
Affinity DataIC50: 15.9nMAssay Description:Compounds disclosed herein were tested for blocking of human IL-17A (Cat: C774, novoprotein) protein with its receptor human IL-17RA (Cat: C153, novo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetInterleukin-17 receptor A/(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 740401BDBM740401(N-((1S)-1-cyclohexyl- 2-((2- (methylcarbamoyl)-2- ...)
Affinity DataIC50: 16nMAssay Description:Compounds disclosed herein were tested for blocking of human IL-17A (Cat: C774, novoprotein) protein with its receptor human IL-17RA (Cat: C153, novo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetInterleukin-17 receptor A/(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 548061BDBM548061(WO2022091056, Example 53)
Affinity DataIC50: 16nMAssay Description: Dilutions of test compounds in DMSO are plated onto white low-volume 384-well plates (Greiner, #784075). Specifically, solutions of graded concentra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2022
Entry Details
WIPO WO2022091056

TargetInterleukin-17 receptor A/(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 548020BDBM548020(WO2022091056, Example 13a)
Affinity DataIC50: 16nMAssay Description: Dilutions of test compounds in DMSO are plated onto white low-volume 384-well plates (Greiner, #784075). Specifically, solutions of graded concentra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2022
Entry Details
WIPO WO2022091056

TargetInterleukin-17 receptor A/(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 740361BDBM740361(N-((1S)-1-cyclohexyl- 2-((2-(((S)-1- cyclohexyl-2-...)
Affinity DataIC50: 16nMAssay Description:Compounds disclosed herein were tested for blocking of human IL-17A (Cat: C774, novoprotein) protein with its receptor human IL-17RA (Cat: C153, novo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetInterleukin-17 receptor A/(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 740390BDBM740390(N-((2S)-1,1- dicyclopropyl-3-((2- ((dicyclopropylm...)
Affinity DataIC50: 16.5nMAssay Description:Compounds disclosed herein were tested for blocking of human IL-17A (Cat: C774, novoprotein) protein with its receptor human IL-17RA (Cat: C153, novo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetInterleukin-17 receptor A/(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 548006BDBM548006(4-chloro-3-(4-((S)-2-cyclohexyl-2-(1-methyl-1H-pyr...)
Affinity DataIC50: 17nMAssay Description: Dilutions of test compounds in DMSO are plated onto white low-volume 384-well plates (Greiner, #784075). Specifically, solutions of graded concentra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2022
Entry Details
WIPO WO2022091056

TargetInterleukin-17 receptor A/(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 548055BDBM548055(WO2022091056, Example 47)
Affinity DataIC50: 17nMAssay Description: Dilutions of test compounds in DMSO are plated onto white low-volume 384-well plates (Greiner, #784075). Specifically, solutions of graded concentra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2022
Entry Details
WIPO WO2022091056

TargetInterleukin-17 receptor A/(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 548046BDBM548046(WO2022091056, Example 38)
Affinity DataIC50: 17nMAssay Description: Dilutions of test compounds in DMSO are plated onto white low-volume 384-well plates (Greiner, #784075). Specifically, solutions of graded concentra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2022
Entry Details
WIPO WO2022091056

TargetInterleukin-17 receptor A/(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 740388BDBM740388(N-((2S)-1,1- dicyclopropyl-3-((2- ((R)-4-isopropyl...)
Affinity DataIC50: 17.3nMAssay Description:Compounds disclosed herein were tested for blocking of human IL-17A (Cat: C774, novoprotein) protein with its receptor human IL-17RA (Cat: C153, novo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetInterleukin-17 receptor A/(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 548075BDBM548075(WO2022091056, Example 66)
Affinity DataIC50: 18nMAssay Description: Dilutions of test compounds in DMSO are plated onto white low-volume 384-well plates (Greiner, #784075). Specifically, solutions of graded concentra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2022
Entry Details
WIPO WO2022091056

TargetInterleukin-17 receptor A/(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 740299BDBM740299(N-(2-((2-((R)-4- isopropyl-2- oxoimidazolidin-1-yl...)
Affinity DataIC50: 18nMAssay Description:Compounds disclosed herein were tested for blocking of human IL-17A (Cat: C774, novoprotein) protein with its receptor human IL-17RA (Cat: C153, novo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetInterleukin-17 receptor A/(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 548054BDBM548054(WO2022091056, Example 46)
Affinity DataIC50: 18nMAssay Description: Dilutions of test compounds in DMSO are plated onto white low-volume 384-well plates (Greiner, #784075). Specifically, solutions of graded concentra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2022
Entry Details
WIPO WO2022091056

TargetInterleukin-17 receptor A/(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 548070BDBM548070(WO2022091056, Example 61)
Affinity DataIC50: 18nMAssay Description: Dilutions of test compounds in DMSO are plated onto white low-volume 384-well plates (Greiner, #784075). Specifically, solutions of graded concentra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2022
Entry Details
WIPO WO2022091056

TargetInterleukin-17 receptor A/(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 740408BDBM740408(N-((S)-1,1- dicyclopropyl-3-((2- (cyclopropyl((S)-...)
Affinity DataIC50: 18.6nMAssay Description:Compounds disclosed herein were tested for blocking of human IL-17A (Cat: C774, novoprotein) protein with its receptor human IL-17RA (Cat: C153, novo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetInterleukin-17 receptor A/(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 740359BDBM740359(N-((2S)-1,1- dicyclopropyl-3-((2- (methylcarbamoyl...)
Affinity DataIC50: 19nMAssay Description:Compounds disclosed herein were tested for blocking of human IL-17A (Cat: C774, novoprotein) protein with its receptor human IL-17RA (Cat: C153, novo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetInterleukin-17 receptor A/(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 740153BDBM740153(N-((1S)-1-cyclohexyl- 2-((2-((R)-4-isopropyl- 2-ox...)
Affinity DataIC50: 19nMAssay Description:Compounds disclosed herein were tested for blocking of human IL-17A (Cat: C774, novoprotein) protein with its receptor human IL-17RA (Cat: C153, novo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetInterleukin-17 receptor A/(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 740367BDBM740367(N-((1S)-1-cyclohexyl- 2-((2- (isobutylcarbamoyl)-2...)
Affinity DataIC50: 19nMAssay Description:Compounds disclosed herein were tested for blocking of human IL-17A (Cat: C774, novoprotein) protein with its receptor human IL-17RA (Cat: C153, novo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetInterleukin-17 receptor A/(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 740379BDBM740379(4-cyano-N-((1S)-1- cyclohexyl-2-((2- (methylcarbam...)
Affinity DataIC50: 19nMAssay Description:Compounds disclosed herein were tested for blocking of human IL-17A (Cat: C774, novoprotein) protein with its receptor human IL-17RA (Cat: C153, novo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetInterleukin-17 receptor A/(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 548116BDBM548116(WO2022091056, Example 107)
Affinity DataIC50: 19nMAssay Description: Dilutions of test compounds in DMSO are plated onto white low-volume 384-well plates (Greiner, #784075). Specifically, solutions of graded concentra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2022
Entry Details
WIPO WO2022091056

TargetInterleukin-17 receptor A/(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 740218BDBM740218(N-(1-(7-chloro-1,2,3,4- tetrahydronaphthalen-2- yl...)
Affinity DataIC50: 19.8nMAssay Description:Compounds disclosed herein were tested for blocking of human IL-17A (Cat: C774, novoprotein) protein with its receptor human IL-17RA (Cat: C153, novo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetInterleukin-17 receptor A/(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 740233BDBM740233(N-((1S)-1-cyclohexyl- 2-((2-((R)-4-(4- methoxybenz...)
Affinity DataIC50: 20nMAssay Description:Compounds disclosed herein were tested for blocking of human IL-17A (Cat: C774, novoprotein) protein with its receptor human IL-17RA (Cat: C153, novo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetInterleukin-17 receptor A/(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 740127BDBM740127(N-((1S)-1-cyclohexyl- 2-((2-((R)-4-isopropyl- 2-ox...)
Affinity DataIC50: 20nMAssay Description:Compounds disclosed herein were tested for blocking of human IL-17A (Cat: C774, novoprotein) protein with its receptor human IL-17RA (Cat: C153, novo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetInterleukin-17 receptor A/(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 548036BDBM548036(WO2022091056, Example 28)
Affinity DataIC50: 20nMAssay Description: Dilutions of test compounds in DMSO are plated onto white low-volume 384-well plates (Greiner, #784075). Specifically, solutions of graded concentra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2022
Entry Details
WIPO WO2022091056

TargetInterleukin-17 receptor A/(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 740320BDBM740320(N-((1S)-1-(4,4- difluorocyclohexyl)-2- ((2-(2-hydr...)
Affinity DataIC50: 20.9nMAssay Description:Compounds disclosed herein were tested for blocking of human IL-17A (Cat: C774, novoprotein) protein with its receptor human IL-17RA (Cat: C153, novo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetInterleukin-17 receptor A/(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 740263BDBM740263(5-((S)-2-cyclohexyl-2- (3- methylbenzamido) acetam...)
Affinity DataIC50: 21nMAssay Description:Compounds disclosed herein were tested for blocking of human IL-17A (Cat: C774, novoprotein) protein with its receptor human IL-17RA (Cat: C153, novo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetInterleukin-17 receptor A/(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 548065BDBM548065(WO2022091056, Example 56)
Affinity DataIC50: 21nMAssay Description: Dilutions of test compounds in DMSO are plated onto white low-volume 384-well plates (Greiner, #784075). Specifically, solutions of graded concentra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2022
Entry Details
WIPO WO2022091056

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