Compile Data Set for Download or QSAR
Report error Found 1067 Enz. Inhib. hit(s) with Target = 'Isoform 2 of Nuclear receptor ROR-gamma (RORgT)'
TargetIsoform 2 of Nuclear receptor ROR-gamma (RORgT)(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 220248BDBM220248(US9290476, 93)
Affinity DataKd:  0.0170nMpH: 7.0 T: 2°CAssay Description:Bar-coded assay plates are robotically loaded onto a thermostatically controlled PCR-type thermal block and then heated at a typical ramp-rate of 1 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
US Patent

TargetIsoform 2 of Nuclear receptor ROR-gamma (RORgT)(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 50058935BDBM50058935(CHEMBL3358455 | US9290476, 79C)
Affinity DataKd:  0.0240nMpH: 7.0 T: 2°CAssay Description:Bar-coded assay plates are robotically loaded onto a thermostatically controlled PCR-type thermal block and then heated at a typical ramp-rate of 1 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
US Patent

TargetIsoform 2 of Nuclear receptor ROR-gamma (RORgT)(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 220235BDBM220235(US9290476, 80C | US9290476, 80B | US9290476, 80A)
Affinity DataKd:  0.0260nMpH: 7.0 T: 2°CAssay Description:Bar-coded assay plates are robotically loaded onto a thermostatically controlled PCR-type thermal block and then heated at a typical ramp-rate of 1 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
US Patent

TargetIsoform 2 of Nuclear receptor ROR-gamma (RORgT)(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 220342BDBM220342(US9290476, 88C | US9290476, 88B)
Affinity DataKd:  0.0400nMpH: 7.0 T: 2°CAssay Description:Bar-coded assay plates are robotically loaded onto a thermostatically controlled PCR-type thermal block and then heated at a typical ramp-rate of 1 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
US Patent

TargetIsoform 2 of Nuclear receptor ROR-gamma (RORgT)(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 220236BDBM220236(US9290476, 81C | US9290476, 81B | US9290476, 81A)
Affinity DataKd:  0.0500nMpH: 7.0 T: 2°CAssay Description:Bar-coded assay plates are robotically loaded onto a thermostatically controlled PCR-type thermal block and then heated at a typical ramp-rate of 1 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
US Patent

TargetIsoform 2 of Nuclear receptor ROR-gamma (RORgT)(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 220235BDBM220235(US9290476, 80C | US9290476, 80B | US9290476, 80A)
Affinity DataKd:  0.110nMpH: 7.0 T: 2°CAssay Description:Bar-coded assay plates are robotically loaded onto a thermostatically controlled PCR-type thermal block and then heated at a typical ramp-rate of 1 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
US Patent

TargetIsoform 2 of Nuclear receptor ROR-gamma (RORgT)(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 220236BDBM220236(US9290476, 81C | US9290476, 81B | US9290476, 81A)
Affinity DataKd:  0.120nMpH: 7.0 T: 2°CAssay Description:Bar-coded assay plates are robotically loaded onto a thermostatically controlled PCR-type thermal block and then heated at a typical ramp-rate of 1 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
US Patent

TargetIsoform 2 of Nuclear receptor ROR-gamma (RORgT)(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 220236BDBM220236(US9290476, 81C | US9290476, 81B | US9290476, 81A)
Affinity DataKd:  0.120nMpH: 7.0 T: 2°CAssay Description:Bar-coded assay plates are robotically loaded onto a thermostatically controlled PCR-type thermal block and then heated at a typical ramp-rate of 1 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
US Patent

TargetIsoform 2 of Nuclear receptor ROR-gamma (RORgT)(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 220235BDBM220235(US9290476, 80C | US9290476, 80B | US9290476, 80A)
Affinity DataKd:  0.140nMpH: 7.0 T: 2°CAssay Description:Bar-coded assay plates are robotically loaded onto a thermostatically controlled PCR-type thermal block and then heated at a typical ramp-rate of 1 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
US Patent

TargetIsoform 2 of Nuclear receptor ROR-gamma (RORgT)(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 220233BDBM220233(US9290476, 77C | US9290476, 77B | US9290476, 77A)
Affinity DataKd:  0.140nMpH: 7.0 T: 2°CAssay Description:Bar-coded assay plates are robotically loaded onto a thermostatically controlled PCR-type thermal block and then heated at a typical ramp-rate of 1 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
US Patent

TargetIsoform 2 of Nuclear receptor ROR-gamma (RORgT)(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 220246BDBM220246(US9290476, 91C | US9290476, 91B | US9290476, 91A)
Affinity DataKd:  0.230nMpH: 7.0 T: 2°CAssay Description:Bar-coded assay plates are robotically loaded onto a thermostatically controlled PCR-type thermal block and then heated at a typical ramp-rate of 1 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
US Patent

TargetIsoform 2 of Nuclear receptor ROR-gamma (RORgT)(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 220246BDBM220246(US9290476, 91C | US9290476, 91B | US9290476, 91A)
Affinity DataKd:  0.25nMpH: 7.0 T: 2°CAssay Description:Bar-coded assay plates are robotically loaded onto a thermostatically controlled PCR-type thermal block and then heated at a typical ramp-rate of 1 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
US Patent

TargetIsoform 2 of Nuclear receptor ROR-gamma (RORgT)(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 220234BDBM220234(US9290476, 78C | US9290476, 78B | US9290476, 78A)
Affinity DataKd:  0.280nMpH: 7.0 T: 2°CAssay Description:Bar-coded assay plates are robotically loaded onto a thermostatically controlled PCR-type thermal block and then heated at a typical ramp-rate of 1 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
US Patent

TargetIsoform 2 of Nuclear receptor ROR-gamma (RORgT)(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 220213BDBM220213(US9290476, 56)
Affinity DataKd:  0.290nMpH: 7.0 T: 2°CAssay Description:Bar-coded assay plates are robotically loaded onto a thermostatically controlled PCR-type thermal block and then heated at a typical ramp-rate of 1 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
US Patent

TargetIsoform 2 of Nuclear receptor ROR-gamma (RORgT)(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 220245BDBM220245(US9290476, 90C | US9290476, 90B | US9290476, 90A)
Affinity DataKd:  0.320nMpH: 7.0 T: 2°CAssay Description:Bar-coded assay plates are robotically loaded onto a thermostatically controlled PCR-type thermal block and then heated at a typical ramp-rate of 1 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
US Patent

TargetIsoform 2 of Nuclear receptor ROR-gamma (RORgT)(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 220245BDBM220245(US9290476, 90C | US9290476, 90B | US9290476, 90A)
Affinity DataKd:  0.440nMpH: 7.0 T: 2°CAssay Description:Bar-coded assay plates are robotically loaded onto a thermostatically controlled PCR-type thermal block and then heated at a typical ramp-rate of 1 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
US Patent

TargetIsoform 2 of Nuclear receptor ROR-gamma (RORgT)(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 220234BDBM220234(US9290476, 78C | US9290476, 78B | US9290476, 78A)
Affinity DataKd:  0.520nMpH: 7.0 T: 2°CAssay Description:Bar-coded assay plates are robotically loaded onto a thermostatically controlled PCR-type thermal block and then heated at a typical ramp-rate of 1 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
US Patent

TargetIsoform 2 of Nuclear receptor ROR-gamma (RORgT)(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 220245BDBM220245(US9290476, 90C | US9290476, 90B | US9290476, 90A)
Affinity DataKd:  0.560nMpH: 7.0 T: 2°CAssay Description:Bar-coded assay plates are robotically loaded onto a thermostatically controlled PCR-type thermal block and then heated at a typical ramp-rate of 1 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
US Patent

TargetIsoform 2 of Nuclear receptor ROR-gamma (RORgT)(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 220237BDBM220237(US9290476, 82)
Affinity DataKd:  0.630nMpH: 7.0 T: 2°CAssay Description:Bar-coded assay plates are robotically loaded onto a thermostatically controlled PCR-type thermal block and then heated at a typical ramp-rate of 1 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
US Patent

TargetIsoform 2 of Nuclear receptor ROR-gamma (RORgT)(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 392065BDBM392065(US10301272, Example 6/63)
Affinity DataIC50: 0.631nMAssay Description:Cells were incubated for additional 16 h before firefly (FF) luciferase activities were measured sequentially in the same cell extract using a Dual-L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent

TargetIsoform 2 of Nuclear receptor ROR-gamma (RORgT)(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 220252BDBM220252(US9290476, 97B | US9290476, 97C | US9290476, 97A)
Affinity DataKd:  0.640nMpH: 7.0 T: 2°CAssay Description:Bar-coded assay plates are robotically loaded onto a thermostatically controlled PCR-type thermal block and then heated at a typical ramp-rate of 1 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
US Patent

TargetIsoform 2 of Nuclear receptor ROR-gamma (RORgT)(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 50058934BDBM50058934(CHEMBL3325743 | US9290476, 72C)
Affinity DataKd:  0.710nMpH: 7.0 T: 2°CAssay Description:Bar-coded assay plates are robotically loaded onto a thermostatically controlled PCR-type thermal block and then heated at a typical ramp-rate of 1 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
US Patent

TargetIsoform 2 of Nuclear receptor ROR-gamma (RORgT)(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 220244BDBM220244(US9290476, 89)
Affinity DataKd:  0.770nMpH: 7.0 T: 2°CAssay Description:Bar-coded assay plates are robotically loaded onto a thermostatically controlled PCR-type thermal block and then heated at a typical ramp-rate of 1 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
US Patent

TargetIsoform 2 of Nuclear receptor ROR-gamma (RORgT)(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 220166BDBM220166(US9290476, 9)
Affinity DataKd:  0.830nMpH: 7.0 T: 2°CAssay Description:Bar-coded assay plates are robotically loaded onto a thermostatically controlled PCR-type thermal block and then heated at a typical ramp-rate of 1 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
US Patent

TargetIsoform 2 of Nuclear receptor ROR-gamma (RORgT)(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 392102BDBM392102(US10301272, Example 8/7)
Affinity DataIC50: 1nMAssay Description:Cells were incubated for additional 16 h before renilla (REN) luciferase activities were measured sequentially in the same cell extract using a Dual-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent

TargetIsoform 2 of Nuclear receptor ROR-gamma (RORgT)(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 392136BDBM392136(US10301272, Example 14/6)
Affinity DataIC50: 1nMAssay Description:Cells were incubated for additional 16 h before firefly (FF) luciferase activities were measured sequentially in the same cell extract using a Dual-L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent

TargetIsoform 2 of Nuclear receptor ROR-gamma (RORgT)(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 392013BDBM392013(US10301272, Example 6/11)
Affinity DataIC50: 1nMAssay Description:Cells were incubated for additional 16 h before firefly (FF) luciferase activities were measured sequentially in the same cell extract using a Dual-L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent

TargetIsoform 2 of Nuclear receptor ROR-gamma (RORgT)(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 50044179BDBM50044179(CHEMBL3314002 | US10301272, Example 7/4)
Affinity DataIC50: 1nMAssay Description:Cells were incubated for additional 16 h before renilla (REN) luciferase activities were measured sequentially in the same cell extract using a Dual-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent

TargetIsoform 2 of Nuclear receptor ROR-gamma (RORgT)(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 50044179BDBM50044179(CHEMBL3314002 | US10301272, Example 7/4)
Affinity DataIC50: 1nMAssay Description:Cells were incubated for additional 16 h before firefly (FF) luciferase activities were measured sequentially in the same cell extract using a Dual-L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent

TargetIsoform 2 of Nuclear receptor ROR-gamma (RORgT)(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 392136BDBM392136(US10301272, Example 14/6)
Affinity DataIC50: 1nMAssay Description:Cells were incubated for additional 16 h before renilla (REN) luciferase activities were measured sequentially in the same cell extract using a Dual-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent

TargetIsoform 2 of Nuclear receptor ROR-gamma (RORgT)(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 392008BDBM392008(US10301272, Example 6/6)
Affinity DataIC50: 1nMAssay Description:Cells were incubated for additional 16 h before renilla (REN) luciferase activities were measured sequentially in the same cell extract using a Dual-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent

TargetIsoform 2 of Nuclear receptor ROR-gamma (RORgT)(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 392008BDBM392008(US10301272, Example 6/6)
Affinity DataIC50: 1nMAssay Description:Cells were incubated for additional 16 h before firefly (FF) luciferase activities were measured sequentially in the same cell extract using a Dual-L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent

TargetIsoform 2 of Nuclear receptor ROR-gamma (RORgT)(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 392066BDBM392066(US10301272, Example 6/64)
Affinity DataIC50: 1nMAssay Description:Cells were incubated for additional 16 h before renilla (REN) luciferase activities were measured sequentially in the same cell extract using a Dual-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent

TargetIsoform 2 of Nuclear receptor ROR-gamma (RORgT)(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 392031BDBM392031(US10301272, Example 6/29)
Affinity DataIC50: 1nMAssay Description:Cells were incubated for additional 16 h before renilla (REN) luciferase activities were measured sequentially in the same cell extract using a Dual-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent

TargetIsoform 2 of Nuclear receptor ROR-gamma (RORgT)(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 392031BDBM392031(US10301272, Example 6/29)
Affinity DataIC50: 1nMAssay Description:Cells were incubated for additional 16 h before firefly (FF) luciferase activities were measured sequentially in the same cell extract using a Dual-L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent

TargetIsoform 2 of Nuclear receptor ROR-gamma (RORgT)(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 392075BDBM392075(US10301272, Example 7/8)
Affinity DataIC50: 1nMAssay Description:Cells were incubated for additional 16 h before renilla (REN) luciferase activities were measured sequentially in the same cell extract using a Dual-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent

TargetIsoform 2 of Nuclear receptor ROR-gamma (RORgT)(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 392075BDBM392075(US10301272, Example 7/8)
Affinity DataIC50: 1nMAssay Description:Cells were incubated for additional 16 h before firefly (FF) luciferase activities were measured sequentially in the same cell extract using a Dual-L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent

TargetIsoform 2 of Nuclear receptor ROR-gamma (RORgT)(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 392202BDBM392202(US10301272, Example 25/2)
Affinity DataIC50: 1nMAssay Description:Cells were incubated for additional 16 h before renilla (REN) luciferase activities were measured sequentially in the same cell extract using a Dual-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent

TargetIsoform 2 of Nuclear receptor ROR-gamma (RORgT)(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 392202BDBM392202(US10301272, Example 25/2)
Affinity DataIC50: 1nMAssay Description:Cells were incubated for additional 16 h before firefly (FF) luciferase activities were measured sequentially in the same cell extract using a Dual-L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent

TargetIsoform 2 of Nuclear receptor ROR-gamma (RORgT)(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 392076BDBM392076(US10301272, Example 7/9)
Affinity DataIC50: 1nMAssay Description:Cells were incubated for additional 16 h before renilla (REN) luciferase activities were measured sequentially in the same cell extract using a Dual-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent

TargetIsoform 2 of Nuclear receptor ROR-gamma (RORgT)(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 392142BDBM392142(US10301272, Example 15/4)
Affinity DataIC50: 1nMAssay Description:Cells were incubated for additional 16 h before renilla (REN) luciferase activities were measured sequentially in the same cell extract using a Dual-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent

TargetIsoform 2 of Nuclear receptor ROR-gamma (RORgT)(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 392013BDBM392013(US10301272, Example 6/11)
Affinity DataIC50: 1nMAssay Description:Cells were incubated for additional 16 h before renilla (REN) luciferase activities were measured sequentially in the same cell extract using a Dual-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent

TargetIsoform 2 of Nuclear receptor ROR-gamma (RORgT)(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 392106BDBM392106(US10301272, Example 8/11)
Affinity DataIC50: 1nMAssay Description:Cells were incubated for additional 16 h before renilla (REN) luciferase activities were measured sequentially in the same cell extract using a Dual-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent

TargetIsoform 2 of Nuclear receptor ROR-gamma (RORgT)(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 392106BDBM392106(US10301272, Example 8/11)
Affinity DataIC50: 1nMAssay Description:Cells were incubated for additional 16 h before firefly (FF) luciferase activities were measured sequentially in the same cell extract using a Dual-L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent

TargetIsoform 2 of Nuclear receptor ROR-gamma (RORgT)(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 220233BDBM220233(US9290476, 77C | US9290476, 77B | US9290476, 77A)
Affinity DataKd:  1.10nMpH: 7.0 T: 2°CAssay Description:Bar-coded assay plates are robotically loaded onto a thermostatically controlled PCR-type thermal block and then heated at a typical ramp-rate of 1 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
US Patent

TargetIsoform 2 of Nuclear receptor ROR-gamma (RORgT)(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 392107BDBM392107(US10301272, Example 8/12)
Affinity DataIC50: 1.26nMAssay Description:Cells were incubated for additional 16 h before renilla (REN) luciferase activities were measured sequentially in the same cell extract using a Dual-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent

TargetIsoform 2 of Nuclear receptor ROR-gamma (RORgT)(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 392066BDBM392066(US10301272, Example 6/64)
Affinity DataIC50: 1.26nMAssay Description:Cells were incubated for additional 16 h before firefly (FF) luciferase activities were measured sequentially in the same cell extract using a Dual-L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent

TargetIsoform 2 of Nuclear receptor ROR-gamma (RORgT)(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 392065BDBM392065(US10301272, Example 6/63)
Affinity DataIC50: 1.26nMAssay Description:Cells were incubated for additional 16 h before renilla (REN) luciferase activities were measured sequentially in the same cell extract using a Dual-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent

TargetIsoform 2 of Nuclear receptor ROR-gamma (RORgT)(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 392107BDBM392107(US10301272, Example 8/12)
Affinity DataIC50: 1.26nMAssay Description:Cells were incubated for additional 16 h before firefly (FF) luciferase activities were measured sequentially in the same cell extract using a Dual-L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent

TargetIsoform 2 of Nuclear receptor ROR-gamma (RORgT)(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 392168BDBM392168(trans-3-(4-(Cyclohexylmethyl-5-(4-(N-(4-fluoro-2-m...)
Affinity DataIC50: 1.26nMAssay Description:Cells were incubated for additional 16 h before renilla (REN) luciferase activities were measured sequentially in the same cell extract using a Dual-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent

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