Compile Data Set for Download or QSAR
Report error Found 277 Enz. Inhib. hit(s) with Target = 'Leukotriene B4 receptor 1/2'
LigandPNGBDBM50013889(5,12-Dihete | CHEMBL65061 | LTB4 | 5,12-Hete | (S-...)
Affinity DataKi:  0.120nMAssay Description:Inhibition of specific binding of [3H]-LTB4 to LTB4 receptor in guinea pig lung membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2018
Entry Details
PDB3D3D Structure (crystal)
LigandPNGBDBM50052021(4-[5-(4-Carbamimidoyl-phenoxy)-pentyloxy]-N,N-diis...)
Affinity DataKi:  1nMAssay Description:Inhibition of leukotriene B4 (LTB4) binding to its receptor on intact human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2018
Entry Details

LigandPNGBDBM50029464(LY-292728 | 5-(2-Carboxy-ethyl)-6-[3-(5-ethyl-4'-f...)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of LTB4-induced up-regulation of human neutrophil CD11b/CD18 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50029460(3-{3-[3-(5-Ethyl-4'-fluoro-2-hydroxy-biphenyl-4-yl...)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of LTB4-induced up-regulation of human neutrophil CD11b/CD18 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50013889(5,12-Dihete | CHEMBL65061 | LTB4 | 5,12-Hete | (S-...)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of specific binding of [3H]LTB4 to LTB4 receptor in human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2018
Entry Details
PDB3D3D Structure (crystal)
LigandPNGBDBM50215854(CHEMBL301829)
Affinity DataIC50: 2nMAssay Description:Ability to inhibit LTB4-induced chemotaxis of isolated human neutrophils.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2018
Entry Details Article
PubMed
LigandPNGBDBM50215854(CHEMBL301829)
Affinity DataIC50: 2nMAssay Description:Ability to inhibit LTB4-induced chemotaxis of isolated human neutrophils.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2018
Entry Details Article
PubMed
LigandPNGBDBM50215854(CHEMBL301829)
Affinity DataIC50: 2.40nMAssay Description:Ability to inhibit LTB4-induced chemotaxis of isolated human neutrophils.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2018
Entry Details Article
PubMed
LigandPNGBDBM50231624(CHEMBL129703)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of [3H]LTB4 receptor binding in human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2019
Entry Details Article
PubMed
LigandPNGBDBM50231606(CHEMBL128755)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of [3H]LTB4 receptor binding in human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2019
Entry Details Article
PubMed
LigandPNGBDBM50231625(CHEMBL128067)
Affinity DataIC50: 3nMAssay Description:Inhibition of [3H]LTB4 receptor binding in human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2019
Entry Details Article
PubMed
LigandPNGBDBM50231626(CHEMBL128013)
Affinity DataIC50: 3nMAssay Description:Inhibition of [3H]LTB4 receptor binding in human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2019
Entry Details Article
PubMed
LigandPNGBDBM50215738(CHEMBL52675)
Affinity DataIC50: 3nMAssay Description:Ability to inhibit LTB4 binding to LTB receptors on isolated human neutrophils.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2018
Entry Details Article
PubMed
LigandPNGBDBM50037218(1-((3S,4R)-3-Biphenyl-4-ylmethyl-4-hydroxy-chroman...)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of leukotriene B4 (LTB4) binding to guinea pig spleenMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2018
Entry Details

LigandPNGBDBM50029477(5-(2-Carboxy-ethyl)-6-[3-(5-ethyl-2-hydroxy-biphen...)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of LTB4-induced up-regulation of human neutrophil CD11b/CD18 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50037218(1-((3S,4R)-3-Biphenyl-4-ylmethyl-4-hydroxy-chroman...)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of LTB4 receptor induced chemotaxis of isolated human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2018
Entry Details

LigandPNGBDBM50037218(1-((3S,4R)-3-Biphenyl-4-ylmethyl-4-hydroxy-chroman...)
Affinity DataIC50: 3.70nMAssay Description:Inhibition of LTB4 receptor induced chemotaxis of isolated human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2018
Entry Details

LigandPNGBDBM50037218(1-((3S,4R)-3-Biphenyl-4-ylmethyl-4-hydroxy-chroman...)
Affinity DataIC50: 3.70nMAssay Description:Inhibition of LTB4 receptor induced chemotaxis of isolated human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2018
Entry Details

LigandPNGBDBM50231624(CHEMBL129703)
Affinity DataKi:  3.70nMAssay Description:Inhibition of [3H]LTB4 receptor binding in guinea pig lung membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2019
Entry Details Article
PubMed
LigandPNGBDBM50231631(CHEMBL128675)
Affinity DataIC50: 4nMAssay Description:Inhibition of [3H]LTB4 receptor binding in human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2019
Entry Details Article
PubMed
LigandPNGBDBM50231607(CHEMBL127218)
Affinity DataIC50: 4nMAssay Description:Inhibition of [3H]LTB4 receptor binding in human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2019
Entry Details Article
PubMed
LigandPNGBDBM50215740(CHEMBL48906)
Affinity DataIC50: 4nMAssay Description:Ability to inhibit LTB4 binding to LTB receptors on isolated human neutrophils.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2018
Entry Details Article
PubMed
LigandPNGBDBM50215740(CHEMBL48906)
Affinity DataIC50: 4nMAssay Description:Ability to inhibit LTB4 binding to LTB receptors on isolated human neutrophils.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2018
Entry Details Article
PubMed
LigandPNGBDBM50231626(CHEMBL128013)
Affinity DataKi:  4.40nMAssay Description:Inhibition of [3H]LTB4 receptor binding in guinea pig lung membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2019
Entry Details Article
PubMed
LigandPNGBDBM50215855(CHEMBL51467)
Affinity DataIC50: 5nMAssay Description:Ability to inhibit LTB4 binding to LTB receptors on isolated human neutrophils.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2018
Entry Details Article
PubMed
LigandPNGBDBM50215738(CHEMBL52675)
Affinity DataIC50: 5nMAssay Description:Ability to inhibit LTB4-induced chemotaxis of isolated human neutrophils.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2018
Entry Details Article
PubMed
LigandPNGBDBM50215738(CHEMBL52675)
Affinity DataIC50: 5nMAssay Description:Ability to inhibit LTB4-induced chemotaxis of isolated human neutrophils.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2018
Entry Details Article
PubMed
LigandPNGBDBM50231603(CHEMBL128859)
Affinity DataIC50: 5nMAssay Description:Inhibition of [3H]LTB4 receptor binding in human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2019
Entry Details Article
PubMed
LigandPNGBDBM50029448(3-{3-[3-(5-Ethyl-2-hydroxy-biphenyl-4-yloxy)-propo...)
Affinity DataIC50: 5.40nMAssay Description:Inhibition of LTB4-induced up-regulation of human neutrophil CD11b/CD18 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50037218(1-((3S,4R)-3-Biphenyl-4-ylmethyl-4-hydroxy-chroman...)
Affinity DataIC50: 5.5nMAssay Description:Ability to inhibit LTB4-induced CD11b up-regulation on isolated human neutrophils in whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2018
Entry Details Article
PubMed
LigandPNGBDBM50037218(1-((3S,4R)-3-Biphenyl-4-ylmethyl-4-hydroxy-chroman...)
Affinity DataIC50: 5.60nMAssay Description:Inhibition of leukotriene B4 (LTB4) binding to guinea pig spleenMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2018
Entry Details

LigandPNGBDBM50037218(1-((3S,4R)-3-Biphenyl-4-ylmethyl-4-hydroxy-chroman...)
Affinity DataIC50: 5.60nMAssay Description:Inhibition of leukotriene B4 (LTB4) binding to guinea pig spleenMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2018
Entry Details

LigandPNGBDBM50215853(CHEMBL417364)
Affinity DataIC50: 6nMAssay Description:Ability to inhibit LTB4-induced chemotaxis of isolated human neutrophils.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2018
Entry Details Article
PubMed
LigandPNGBDBM50215853(CHEMBL417364)
Affinity DataIC50: 6nMAssay Description:Ability to inhibit LTB4-induced chemotaxis of isolated human neutrophils.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2018
Entry Details Article
PubMed
LigandPNGBDBM50231625(CHEMBL128067)
Affinity DataKi:  6.20nMAssay Description:Inhibition of [3H]LTB4 receptor binding in guinea pig lung membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2019
Entry Details Article
PubMed
LigandPNGBDBM50037218(1-((3S,4R)-3-Biphenyl-4-ylmethyl-4-hydroxy-chroman...)
Affinity DataIC50: 6.40nMAssay Description:Compound was evaluated for its ability to inhibit [3H]LTB4 binding to LTB4 receptors on guinea pig spleen membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2018
Entry Details Article
PubMed
LigandPNGBDBM50215854(CHEMBL301829)
Affinity DataIC50: 6.80nMAssay Description:Ability to inhibit LTB4 binding to LTB receptors on isolated human neutrophils.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2018
Entry Details Article
PubMed
LigandPNGBDBM50231630(CHEMBL127274)
Affinity DataIC50: 8nMAssay Description:Inhibition of [3H]LTB4 receptor binding in human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2019
Entry Details Article
PubMed
LigandPNGBDBM50215737(CHEMBL50425)
Affinity DataIC50: 8nMAssay Description:Ability to inhibit LTB4 binding to LTB receptors on isolated human neutrophils.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2018
Entry Details Article
PubMed
LigandPNGBDBM50215737(CHEMBL50425)
Affinity DataIC50: 8nMAssay Description:Ability to inhibit LTB4 binding to LTB receptors on isolated human neutrophils.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2018
Entry Details Article
PubMed
LigandPNGBDBM50036750(sodium 2-ethoxy-4-ethyl-5-[6-methyl-6-(2H-1,2,3,4-...)
Affinity DataIC50: 8.40nMAssay Description:Inhibition of [3H]LTB4 receptor binding in human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2019
Entry Details Article
PubMed
LigandPNGBDBM50037218(1-((3S,4R)-3-Biphenyl-4-ylmethyl-4-hydroxy-chroman...)
Affinity DataIC50: 8.40nMAssay Description:Ability to inhibit LTB4 binding to LTB receptors on isolated human neutrophils.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2018
Entry Details Article
PubMed
LigandPNGBDBM50215739(CHEMBL52374)
Affinity DataIC50: 9nMAssay Description:Ability to inhibit LTB4-induced chemotaxis of isolated human neutrophils.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2018
Entry Details Article
PubMed
LigandPNGBDBM50036743(Sodium salt of 4-Ethyl-5-[6-methyl-6-(2H-tetrazol-...)
Affinity DataIC50: 9.30nMAssay Description:Inhibition of [3H]LTB4 receptor binding in human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2019
Entry Details Article
PubMed
LigandPNGBDBM50215861(CHEMBL298724)
Affinity DataIC50: 10nMAssay Description:Ability to inhibit LTB4-induced chemotaxis of isolated human neutrophils.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2018
Entry Details Article
PubMed
LigandPNGBDBM50215861(CHEMBL298724)
Affinity DataIC50: 10nMAssay Description:Ability to inhibit LTB4-induced chemotaxis of isolated human neutrophils.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2018
Entry Details Article
PubMed
LigandPNGBDBM50231627(CHEMBL128888)
Affinity DataIC50: 11nMAssay Description:Inhibition of [3H]LTB4 receptor binding in human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2019
Entry Details Article
PubMed
LigandPNGBDBM50215861(CHEMBL298724)
Affinity DataIC50: 11nMAssay Description:Ability to inhibit LTB4 binding to LTB receptors on isolated human neutrophils.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2018
Entry Details Article
PubMed
LigandPNGBDBM50215738(CHEMBL52675)
Affinity DataIC50: 12nMAssay Description:Ability to inhibit LTB4 binding to LTB receptors on isolated human neutrophils.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2018
Entry Details Article
PubMed
LigandPNGBDBM50215738(CHEMBL52675)
Affinity DataIC50: 12nMAssay Description:Ability to inhibit LTB4 binding to LTB receptors on isolated human neutrophils.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2018
Entry Details Article
PubMed
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