Compile Data Set for Download or QSAR
Report error Found 317 Enz. Inhib. hit(s) with Target = 'MAP kinase-activated protein kinase 5'
LigandChemical structure of BindingDB Monomer ID 605909BDBM605909(US11680056, Example 53A | US11680056, Example 53B)
Affinity DataIC50: 0.126nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 605939BDBM605939(US11680056, Example 68B)
Affinity DataIC50: 0.200nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 605929BDBM605929(US11680056, Example 63B)
Affinity DataIC50: 0.316nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 605911BDBM605911(US11680056, Example 54A | US11680056, Example 54B)
Affinity DataIC50: 0.631nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 605920BDBM605920(US11680056, Example 59A | US11680056, Example 59B)
In Depth
Date in BDB:
7/25/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 605916BDBM605916(US11680056, Example 57A | US11680056, Example 57B)
Affinity DataIC50: 1.26nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 605918BDBM605918(US11680056, Example 58A)
Affinity DataIC50: 1.26nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 605738BDBM605738(US11680056, Example 4 | US11680056, Example 4B | U...)
Affinity DataIC50: 1.58nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 605844BDBM605844(US11680056, Example 24A | US11680056, Example 24B)
Affinity DataIC50: 1.58nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 605926BDBM605926(US11680056, Example 62A)
Affinity DataIC50: 1.58nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 605936BDBM605936(US11680056, Example 67A)
Affinity DataIC50: 1.58nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 605914BDBM605914(US11680056, Example 56A | US11680056, Example 56B)
In Depth
Date in BDB:
7/25/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 605930BDBM605930(US11680056, Example 64A | US11680056, Example 64B)
In Depth
Date in BDB:
7/25/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 605897BDBM605897(US11680056, Example 47A | US11680056, Example 47B)
In Depth
Date in BDB:
7/25/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 605842BDBM605842(US11680056, Example 23A | US11680056, Example 23B)
Affinity DataIC50: 3.16nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 605924BDBM605924(US11680056, Example 61A | US11680056, Example 61B)
Affinity DataIC50: 3.16nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 605838BDBM605838(US11680056, Example 21A | US11680056, Example 21B)
Affinity DataIC50: 3.16nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 605932BDBM605932(US11680056, Example 65A | US11680056, Example 65B)
Affinity DataIC50: 3.98nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 605824BDBM605824(US11680056, Example 9A)
Affinity DataIC50: 3.98nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2023
Entry Details
US Patent

TargetMAP kinase-activated protein kinase 5(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50395272BDBM50395272(CHEMBL1231206)
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant PRAK (unknown origin) expressed in Escherichia coli using KKKALSRQLSVAA as substrate incubated for 1 hr followed by substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 605899BDBM605899(US11680056, Example 48A | US11680056, Example 48B)
Affinity DataIC50: 5.01nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 605817BDBM605817(US11680056, Example 6 | US11680056, Example 6B | U...)
Affinity DataIC50: 5.01nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 605877BDBM605877(US11680056, Example 37A | US11680056, Example 37B)
Affinity DataIC50: 5.01nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 605885BDBM605885(US11680056, Example 41A)
Affinity DataIC50: 5.01nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 605873BDBM605873(US11680056, Example 36A)
Affinity DataIC50: 5.01nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 605874BDBM605874(US11680056, Example 36B)
Affinity DataIC50: 6.31nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 605901BDBM605901(US11680056, Example 49A | US11680056, Example 49B)
Affinity DataIC50: 6.31nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 605935BDBM605935(US11680056, Example 66B)
Affinity DataIC50: 6.31nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 605854BDBM605854(US11680056, Example 29A | US11680056, Example 29B)
Affinity DataIC50: 7.94nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2023
Entry Details
US Patent

TargetMAP kinase-activated protein kinase 5(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 31093BDBM31093(cid_11712649 | 4-[[7-[2,6-bis(fluoranyl)phenyl]-9-...)
Affinity DataKd:  8nMAssay Description:Binding affinity to PRAK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 605916BDBM605916(US11680056, Example 57A | US11680056, Example 57B)
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 605881BDBM605881(US11680056, Example 39A | US11680056, Example 39B)
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 605732BDBM605732(US11680056, Example 3 | US11680056, Example 3A | U...)
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 605903BDBM605903(US11680056, Example 50A | US11680056, Example 50B)
Affinity DataIC50: 12.6nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 605889BDBM605889(US11680056, Example 43A | US11680056, Example 43B)
Affinity DataIC50: 12.6nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 605848BDBM605848(US11680056, Example 26A | US11680056, Example 26B)
Affinity DataIC50: 12.6nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 605907BDBM605907(US11680056, Example 52A | US11680056, Example 52B)
Affinity DataIC50: 15.8nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 605895BDBM605895(US11680056, Example 46A | US11680056, Example 46B)
Affinity DataIC50: 15.8nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 605869BDBM605869(US11680056, Example 35A | US11680056, Example 35B ...)
Affinity DataIC50: 15.8nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 605859BDBM605859(US11680056, Example 32A | US11680056, Example 32B ...)
Affinity DataIC50: 20nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 605865BDBM605865(US11680056, Example 34A)
Affinity DataIC50: 20nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 605891BDBM605891(US11680056, Example 44A | US11680056, Example 44B)
Affinity DataIC50: 25.1nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 605923BDBM605923(US11680056, Example 60B)
Affinity DataIC50: 25.1nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 605863BDBM605863(US11680056, Example 33A | US11680056, Example 33B)
Affinity DataIC50: 25.1nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2023
Entry Details
US Patent

TargetMAP kinase-activated protein kinase 5(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50652793BDBM50652793(CHEMBL5653589)
Affinity DataKd:  44nMAssay Description:Binding affinity to human MAPKAPK5 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 605869BDBM605869(US11680056, Example 35A | US11680056, Example 35B ...)
Affinity DataIC50: 50.1nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 605913BDBM605913(US11680056, Example 55)
Affinity DataIC50: 63.1nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 605905BDBM605905(US11680056, Example 51A)
Affinity DataIC50: 79.4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 605937BDBM605937(US11680056, Example 67B)
Affinity DataIC50: 79.4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2023
Entry Details
US Patent

TargetMAP kinase-activated protein kinase 5(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 30185BDBM30185(CHEMBL226403 | Pyrrolopyridine, 16)
Affinity DataIC50: 81nMpH: 7.5 T: 2°CAssay Description:Compounds were evaluated as inhibitors of kinase by measuring their effect on kinase induced phosphorylation of substrate. IC50 values were reported ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2009
Entry Details Article
PubMed
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