Compile Data Set for Download or QSAR
Report error Found 578 Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase kinase kinase 13'
TargetMitogen-activated protein kinase kinase kinase 13(Human)
Department of Health And Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 716313BDBM716313(US20250032489, Compound 216)
Affinity DataKd:  0.220nMAssay Description:One hundred nanograms of glutathione S-transferase (GST)-tagged human LZK pure protein (Carna Biosciences, #09-114) was incubated with 100 ng of GST-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 13(Human)
Department of Health And Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 716317BDBM716317(US20250032489, Compound 220)
Affinity DataKd:  0.970nMAssay Description:One hundred nanograms of glutathione S-transferase (GST)-tagged human LZK pure protein (Carna Biosciences, #09-114) was incubated with 100 ng of GST-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 13(Human)
Department of Health And Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 716308BDBM716308(US20250032489, Compound 207)
Affinity DataKd:  0.970nMAssay Description:One hundred nanograms of glutathione S-transferase (GST)-tagged human LZK pure protein (Carna Biosciences, #09-114) was incubated with 100 ng of GST-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 13(Human)
Department of Health And Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 716316BDBM716316(US20250032489, Compound 219)
Affinity DataKd:  1.5nMAssay Description:One hundred nanograms of glutathione S-transferase (GST)-tagged human LZK pure protein (Carna Biosciences, #09-114) was incubated with 100 ng of GST-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 13(Human)
Department of Health And Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 716318BDBM716318(US20250032489, Compound 221)
Affinity DataKd:  1.80nMAssay Description:One hundred nanograms of glutathione S-transferase (GST)-tagged human LZK pure protein (Carna Biosciences, #09-114) was incubated with 100 ng of GST-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 13(Human)
Department of Health And Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 50609715BDBM50609715(CHEMBL5286166)
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human LZK (9 to 114 residues) expressed in Sf21 cells assessed as reduction in substrate phosphorylat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 13(Human)
Department of Health And Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 716242BDBM716242(US20250032489, Compound 164)
Affinity DataKd:  2.30nMAssay Description:One hundred nanograms of glutathione S-transferase (GST)-tagged human LZK pure protein (Carna Biosciences, #09-114) was incubated with 100 ng of GST-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 13(Human)
Department of Health And Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 716242BDBM716242(US20250032489, Compound 164)
Affinity DataKd:  2.30nMAssay Description:One hundred nanograms of glutathione S-transferase (GST)-tagged human LZK pure protein (Carna Biosciences, #09-114) was incubated with 100 ng of GST-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 13(Human)
Department of Health And Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 50059190BDBM50059190(CHEMBL3393333 | US20250032489, Compound GNE-3511)
Affinity DataIC50: 3nMAssay Description:Inhibition of LZK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetMitogen-activated protein kinase kinase kinase 13(Human)
Department of Health And Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 50059190BDBM50059190(CHEMBL3393333 | US20250032489, Compound GNE-3511)
Affinity DataKd:  3.20nMAssay Description:One hundred nanograms of glutathione S-transferase (GST)-tagged human LZK pure protein (Carna Biosciences, #09-114) was incubated with 100 ng of GST-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetMitogen-activated protein kinase kinase kinase 13(Human)
Department of Health And Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 716244BDBM716244(US20250032489, Compound 161)
Affinity DataKd:  3.30nMAssay Description:One hundred nanograms of glutathione S-transferase (GST)-tagged human LZK pure protein (Carna Biosciences, #09-114) was incubated with 100 ng of GST-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 13(Human)
Department of Health And Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 716322BDBM716322(US20250032489, Compound 225)
Affinity DataKd:  3.30nMAssay Description:One hundred nanograms of glutathione S-transferase (GST)-tagged human LZK pure protein (Carna Biosciences, #09-114) was incubated with 100 ng of GST-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 13(Human)
Department of Health And Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 716244BDBM716244(US20250032489, Compound 161)
Affinity DataKd:  3.30nMAssay Description:One hundred nanograms of glutathione S-transferase (GST)-tagged human LZK pure protein (Carna Biosciences, #09-114) was incubated with 100 ng of GST-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 13(Human)
Department of Health And Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 716251BDBM716251(US20250032489, Compound 162)
Affinity DataKd:  5.80nMAssay Description:One hundred nanograms of glutathione S-transferase (GST)-tagged human LZK pure protein (Carna Biosciences, #09-114) was incubated with 100 ng of GST-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 13(Human)
Department of Health And Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 716252BDBM716252(US20250032489, Compound 98)
Affinity DataKd:  5.90nMAssay Description:One hundred nanograms of glutathione S-transferase (GST)-tagged human LZK pure protein (Carna Biosciences, #09-114) was incubated with 100 ng of GST-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 13(Human)
Department of Health And Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 716252BDBM716252(US20250032489, Compound 98)
Affinity DataKd:  5.90nMAssay Description:One hundred nanograms of glutathione S-transferase (GST)-tagged human LZK pure protein (Carna Biosciences, #09-114) was incubated with 100 ng of GST-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 13(Human)
Department of Health And Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 716251BDBM716251(US20250032489, Compound 162)
Affinity DataKd:  5.90nMAssay Description:One hundred nanograms of glutathione S-transferase (GST)-tagged human LZK pure protein (Carna Biosciences, #09-114) was incubated with 100 ng of GST-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 13(Human)
Department of Health And Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 716252BDBM716252(US20250032489, Compound 98)
Affinity DataKd:  5.90nMAssay Description:One hundred nanograms of glutathione S-transferase (GST)-tagged human LZK pure protein (Carna Biosciences, #09-114) was incubated with 100 ng of GST-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 13(Human)
Department of Health And Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 50609717BDBM50609717(CHEMBL5271665)
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human LZK (9 to 114 residues) expressed in Sf21 cells assessed as reduction in substrate phosphorylat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 13(Human)
Department of Health And Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 50609705BDBM50609705(CHEMBL5268969)
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human LZK (9 to 114 residues) expressed in Sf21 cells assessed as reduction in substrate phosphorylat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 13(Human)
Department of Health And Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 716302BDBM716302(US20250032489, Compound 201)
Affinity DataKd:  6.70nMAssay Description:One hundred nanograms of glutathione S-transferase (GST)-tagged human LZK pure protein (Carna Biosciences, #09-114) was incubated with 100 ng of GST-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 13(Human)
Department of Health And Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 716319BDBM716319(US20250032489, Compound 222)
Affinity DataKd:  6.90nMAssay Description:One hundred nanograms of glutathione S-transferase (GST)-tagged human LZK pure protein (Carna Biosciences, #09-114) was incubated with 100 ng of GST-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 13(Human)
Department of Health And Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 716325BDBM716325(US20250032489, Compound 228)
Affinity DataKd:  7nMAssay Description:One hundred nanograms of glutathione S-transferase (GST)-tagged human LZK pure protein (Carna Biosciences, #09-114) was incubated with 100 ng of GST-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 13(Human)
Department of Health And Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 50609700BDBM50609700(CHEMBL5271972)
Affinity DataIC50: 7nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human LZK (9 to 114 residues) expressed in Sf21 cells assessed as reduction in substrate phosphorylat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 13(Human)
Department of Health And Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 716311BDBM716311(US20250032489, Compound 214)
Affinity DataKd:  7.60nMAssay Description:One hundred nanograms of glutathione S-transferase (GST)-tagged human LZK pure protein (Carna Biosciences, #09-114) was incubated with 100 ng of GST-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 13(Human)
Department of Health And Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 716253BDBM716253(US20250032489, Compound 159)
Affinity DataKd:  7.70nMAssay Description:One hundred nanograms of glutathione S-transferase (GST)-tagged human LZK pure protein (Carna Biosciences, #09-114) was incubated with 100 ng of GST-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 13(Human)
Department of Health And Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 716253BDBM716253(US20250032489, Compound 159)
Affinity DataKd:  7.70nMAssay Description:One hundred nanograms of glutathione S-transferase (GST)-tagged human LZK pure protein (Carna Biosciences, #09-114) was incubated with 100 ng of GST-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 13(Human)
Department of Health And Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 716305BDBM716305(US20250032489, Compound 204)
Affinity DataKd:  8nMAssay Description:One hundred nanograms of glutathione S-transferase (GST)-tagged human LZK pure protein (Carna Biosciences, #09-114) was incubated with 100 ng of GST-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 13(Human)
Department of Health And Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 50609714BDBM50609714(CHEMBL5270353)
Affinity DataIC50: 9nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human LZK (9 to 114 residues) expressed in Sf21 cells assessed as reduction in substrate phosphorylat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 13(Human)
Department of Health And Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 716254BDBM716254(US20250032489, Compound 160)
Affinity DataKd:  9.60nMAssay Description:One hundred nanograms of glutathione S-transferase (GST)-tagged human LZK pure protein (Carna Biosciences, #09-114) was incubated with 100 ng of GST-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 13(Human)
Department of Health And Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 716254BDBM716254(US20250032489, Compound 160)
Affinity DataKd:  9.60nMAssay Description:One hundred nanograms of glutathione S-transferase (GST)-tagged human LZK pure protein (Carna Biosciences, #09-114) was incubated with 100 ng of GST-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 13(Human)
Department of Health And Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 289504BDBM289504(US10093664, Example 68 | 1-(4-(6-amino-5-(tri- flu...)
Affinity DataIC50: 10nMAssay Description:Inhibition of LZK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 13(Human)
Department of Health And Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 716271BDBM716271(US20250032489, Compound 150)
Affinity DataKd:  13nMAssay Description:One hundred nanograms of glutathione S-transferase (GST)-tagged human LZK pure protein (Carna Biosciences, #09-114) was incubated with 100 ng of GST-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 13(Human)
Department of Health And Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 50609716BDBM50609716(CHEMBL5272522)
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human LZK (9 to 114 residues) expressed in Sf21 cells assessed as reduction in substrate phosphorylat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 13(Human)
Department of Health And Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 637196BDBM637196(US20230382904, Compound 116)
Affinity DataIC50: 14nMAssay Description:Assay Protocol for 384 low volume MTP format: 1 μl of test compound was pipetted into test plate; +5 μl LZK solution (10 nM LZK, catalytic ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2024
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 13(Human)
Department of Health And Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 50609697BDBM50609697(Gdc-0134 | Rg-6000 | GDC-0134)
Affinity DataIC50: 14nMAssay Description:Inhibition of LZK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 13(Human)
Department of Health And Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 637244BDBM637244(US20230382904, Compound 159)
Affinity DataIC50: 16nMAssay Description:Assay Protocol for 384 low volume MTP format: 1 μl of test compound was pipetted into test plate; +5 μl LZK solution (10 nM LZK, catalytic ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2024
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 13(Human)
Department of Health And Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 50355504BDBM50355504(CHEMBL1908393)
Affinity DataKd:  16nMAssay Description:Binding constant for LZK kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 13(Human)
Department of Health And Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 50609708BDBM50609708(CHEMBL5281494)
Affinity DataIC50: 17nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human LZK (9 to 114 residues) expressed in Sf21 cells assessed as reduction in substrate phosphorylat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 13(Human)
Department of Health And Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 716301BDBM716301(US20250032489, Compound 200)
Affinity DataKd:  18nMAssay Description:One hundred nanograms of glutathione S-transferase (GST)-tagged human LZK pure protein (Carna Biosciences, #09-114) was incubated with 100 ng of GST-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 13(Human)
Department of Health And Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 716315BDBM716315(US20250032489, Compound 218)
Affinity DataKd:  18nMAssay Description:One hundred nanograms of glutathione S-transferase (GST)-tagged human LZK pure protein (Carna Biosciences, #09-114) was incubated with 100 ng of GST-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 13(Human)
Department of Health And Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 716276BDBM716276(US20250032489, Compound 163)
Affinity DataKd:  20nMAssay Description:One hundred nanograms of glutathione S-transferase (GST)-tagged human LZK pure protein (Carna Biosciences, #09-114) was incubated with 100 ng of GST-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 13(Human)
Department of Health And Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 716281BDBM716281(US20250032489, Compound 169)
Affinity DataKd:  21nMAssay Description:One hundred nanograms of glutathione S-transferase (GST)-tagged human LZK pure protein (Carna Biosciences, #09-114) was incubated with 100 ng of GST-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 13(Human)
Department of Health And Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 716309BDBM716309(US20250032489, Compound 208)
Affinity DataKd:  22nMAssay Description:One hundred nanograms of glutathione S-transferase (GST)-tagged human LZK pure protein (Carna Biosciences, #09-114) was incubated with 100 ng of GST-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 13(Human)
Department of Health And Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 50609712BDBM50609712(CHEMBL5276415)
Affinity DataIC50: 23nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human LZK (9 to 114 residues) expressed in Sf21 cells assessed as reduction in substrate phosphorylat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 13(Human)
Department of Health And Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 716323BDBM716323(US20250032489, Compound 226)
Affinity DataKd:  24nMAssay Description:One hundred nanograms of glutathione S-transferase (GST)-tagged human LZK pure protein (Carna Biosciences, #09-114) was incubated with 100 ng of GST-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 13(Human)
Department of Health And Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 637188BDBM637188(US20230382904, Compound 108)
Affinity DataIC50: 25nMAssay Description:Assay Protocol for 384 low volume MTP format: 1 μl of test compound was pipetted into test plate; +5 μl LZK solution (10 nM LZK, catalytic ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2024
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 13(Human)
Department of Health And Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 716314BDBM716314(US20250032489, Compound 217)
Affinity DataKd:  25nMAssay Description:One hundred nanograms of glutathione S-transferase (GST)-tagged human LZK pure protein (Carna Biosciences, #09-114) was incubated with 100 ng of GST-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 13(Human)
Department of Health And Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 716280BDBM716280(US20250032489, Compound 168)
Affinity DataKd:  25nMAssay Description:One hundred nanograms of glutathione S-transferase (GST)-tagged human LZK pure protein (Carna Biosciences, #09-114) was incubated with 100 ng of GST-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 13(Human)
Department of Health And Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 716320BDBM716320(US20250032489, Compound 223)
Affinity DataKd:  26nMAssay Description:One hundred nanograms of glutathione S-transferase (GST)-tagged human LZK pure protein (Carna Biosciences, #09-114) was incubated with 100 ng of GST-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent

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