Compile Data Set for Download or QSAR
Report error Found 478 Enz. Inhib. hit(s) with Target = 'NADPH oxidase 4'
TargetNADPH oxidase 4(Human)
Alexandria University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50576853BDBM50576853(CHEMBL4859206)
Affinity DataIC50: 11nMAssay Description:Inhibition of human NADPH oxidase 4 by quantitative sandwich enzyme immunoassay techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetNADPH oxidase 4(Human)
Alexandria University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50576853BDBM50576853(CHEMBL4859206)
Affinity DataIC50: 11nMAssay Description:Inhibition of human NADPH oxidase 4 by quantitative sandwich enzyme immunoassay techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetNADPH oxidase 4(Human)
Alexandria University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 807766BDBM807766(US20260132136, Example 96)
Affinity DataIC50: 11nMAssay Description:NOX4 inhibition is assessed utilizing HEK293 cells stably overexpressing human NOX4 (hNOX4), generating constitutively high levels of hydrogen peroxi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetNADPH oxidase 4(Human)
Alexandria University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 807767BDBM807767(US20260132136, Example 97)
Affinity DataIC50: 13nMAssay Description:NOX4 inhibition is assessed utilizing HEK293 cells stably overexpressing human NOX4 (hNOX4), generating constitutively high levels of hydrogen peroxi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetNADPH oxidase 4(Human)
Alexandria University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 807715BDBM807715(2-((4-Chlorobenzyl)thio)-5-fluoro-3-(5-hydroxypyra...)
Affinity DataIC50: 14nMAssay Description:NOX4 inhibition is assessed utilizing HEK293 cells stably overexpressing human NOX4 (hNOX4), generating constitutively high levels of hydrogen peroxi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetNADPH oxidase 4(Human)
Alexandria University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 807775BDBM807775(US20260132136, Example 105)
Affinity DataIC50: 15nMAssay Description:NOX4 inhibition is assessed utilizing HEK293 cells stably overexpressing human NOX4 (hNOX4), generating constitutively high levels of hydrogen peroxi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetNADPH oxidase 4(Human)
Alexandria University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50576851BDBM50576851(CHEMBL1876217)
Affinity DataIC50: 16nMAssay Description:Inhibition of human NADPH oxidase 4 by quantitative sandwich enzyme immunoassay techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetNADPH oxidase 4(Human)
Alexandria University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 807761BDBM807761(US20260132136, Example 91)
Affinity DataIC50: 16nMAssay Description:NOX4 inhibition is assessed utilizing HEK293 cells stably overexpressing human NOX4 (hNOX4), generating constitutively high levels of hydrogen peroxi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetNADPH oxidase 4(Human)
Alexandria University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50576851BDBM50576851(CHEMBL1876217)
Affinity DataIC50: 16nMAssay Description:Inhibition of human NADPH oxidase 4 by quantitative sandwich enzyme immunoassay techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetNADPH oxidase 4(Human)
Alexandria University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 807765BDBM807765(US20260132136, Example 95)
Affinity DataIC50: 18nMAssay Description:NOX4 inhibition is assessed utilizing HEK293 cells stably overexpressing human NOX4 (hNOX4), generating constitutively high levels of hydrogen peroxi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetNADPH oxidase 4(Human)
Alexandria University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 807771BDBM807771(US20260132136, Example 101)
Affinity DataIC50: 20nMAssay Description:NOX4 inhibition is assessed utilizing HEK293 cells stably overexpressing human NOX4 (hNOX4), generating constitutively high levels of hydrogen peroxi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetNADPH oxidase 4(Human)
Alexandria University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 807717BDBM807717(5-Fluoro-3-(5-hydroxypyrazin-2-yl)-2-((4-(trifluor...)
Affinity DataIC50: 20nMAssay Description:NOX4 inhibition is assessed utilizing HEK293 cells stably overexpressing human NOX4 (hNOX4), generating constitutively high levels of hydrogen peroxi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetNADPH oxidase 4(Human)
Alexandria University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50576852BDBM50576852(CHEMBL4849098)
Affinity DataIC50: 22nMAssay Description:Inhibition of human NADPH oxidase 4 by quantitative sandwich enzyme immunoassay techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetNADPH oxidase 4(Human)
Alexandria University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 794077BDBM794077(US20260055120, Example 18)
Affinity DataIC50: 22nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetNADPH oxidase 4(Human)
Alexandria University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50576852BDBM50576852(CHEMBL4849098)
Affinity DataIC50: 22nMAssay Description:Inhibition of human NADPH oxidase 4 by quantitative sandwich enzyme immunoassay techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetNADPH oxidase 4(Human)
Alexandria University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 794086BDBM794086(US20260055120, Example 27)
Affinity DataIC50: 23nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetNADPH oxidase 4(Human)
Alexandria University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 807710BDBM807710(US20260132136, Example 40)
Affinity DataIC50: 24nMAssay Description:NOX4 inhibition is assessed utilizing HEK293 cells stably overexpressing human NOX4 (hNOX4), generating constitutively high levels of hydrogen peroxi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetNADPH oxidase 4(Human)
Alexandria University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 794107BDBM794107(US20260055120, Example 48)
Affinity DataIC50: 24nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetNADPH oxidase 4(Human)
Alexandria University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 794071BDBM794071(US20260055120, Example 12)
Affinity DataIC50: 25nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetNADPH oxidase 4(Human)
Alexandria University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 794075BDBM794075(US20260055120, Example 16)
Affinity DataIC50: 25nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetNADPH oxidase 4(Human)
Alexandria University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 807763BDBM807763(US20260132136, Example 93)
Affinity DataIC50: 25nMAssay Description:NOX4 inhibition is assessed utilizing HEK293 cells stably overexpressing human NOX4 (hNOX4), generating constitutively high levels of hydrogen peroxi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetNADPH oxidase 4(Human)
Alexandria University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 794127BDBM794127(US20260055120, Example 68)
Affinity DataIC50: 25nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetNADPH oxidase 4(Human)
Alexandria University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 807712BDBM807712(US20260132136, Example 42)
Affinity DataIC50: 26nMAssay Description:NOX4 inhibition is assessed utilizing HEK293 cells stably overexpressing human NOX4 (hNOX4), generating constitutively high levels of hydrogen peroxi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetNADPH oxidase 4(Human)
Alexandria University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 807762BDBM807762(US20260132136, Example 92)
Affinity DataIC50: 26nMAssay Description:NOX4 inhibition is assessed utilizing HEK293 cells stably overexpressing human NOX4 (hNOX4), generating constitutively high levels of hydrogen peroxi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetNADPH oxidase 4(Human)
Alexandria University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 794117BDBM794117(5-((4-(Difluoromethyl)-2,6-difluorobenzyl)thio)-6-...)
Affinity DataIC50: 28nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetNADPH oxidase 4(Human)
Alexandria University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 807704BDBM807704(US20260132136, Example 34)
Affinity DataIC50: 28nMAssay Description:NOX4 inhibition is assessed utilizing HEK293 cells stably overexpressing human NOX4 (hNOX4), generating constitutively high levels of hydrogen peroxi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetNADPH oxidase 4(Human)
Alexandria University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 807705BDBM807705(US20260132136, Example 35)
Affinity DataIC50: 28nMAssay Description:NOX4 inhibition is assessed utilizing HEK293 cells stably overexpressing human NOX4 (hNOX4), generating constitutively high levels of hydrogen peroxi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetNADPH oxidase 4(Human)
Alexandria University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 807731BDBM807731(US20260132136, Example 61)
Affinity DataIC50: 28nMAssay Description:NOX4 inhibition is assessed utilizing HEK293 cells stably overexpressing human NOX4 (hNOX4), generating constitutively high levels of hydrogen peroxi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetNADPH oxidase 4(Human)
Alexandria University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 807764BDBM807764(US20260132136, Example 94)
Affinity DataIC50: 28nMAssay Description:NOX4 inhibition is assessed utilizing HEK293 cells stably overexpressing human NOX4 (hNOX4), generating constitutively high levels of hydrogen peroxi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetNADPH oxidase 4(Human)
Alexandria University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 807726BDBM807726(US20260132136, Example 56)
Affinity DataIC50: 29nMAssay Description:NOX4 inhibition is assessed utilizing HEK293 cells stably overexpressing human NOX4 (hNOX4), generating constitutively high levels of hydrogen peroxi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetNADPH oxidase 4(Human)
Alexandria University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 794097BDBM794097(US20260055120, Example 38)
Affinity DataIC50: 29nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetNADPH oxidase 4(Human)
Alexandria University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 807727BDBM807727(US20260132136, Example 57)
Affinity DataIC50: 30nMAssay Description:NOX4 inhibition is assessed utilizing HEK293 cells stably overexpressing human NOX4 (hNOX4), generating constitutively high levels of hydrogen peroxi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetNADPH oxidase 4(Human)
Alexandria University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 794076BDBM794076(US20260055120, Example 17)
Affinity DataIC50: 31nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetNADPH oxidase 4(Human)
Alexandria University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 807746BDBM807746(US20260132136, Example 76)
Affinity DataIC50: 31nMAssay Description:NOX4 inhibition is assessed utilizing HEK293 cells stably overexpressing human NOX4 (hNOX4), generating constitutively high levels of hydrogen peroxi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetNADPH oxidase 4(Human)
Alexandria University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 807828BDBM807828(2-((4-Chlorobenzyl)thio)-3-(5-fluoro-6-hydroxypyri...)
Affinity DataIC50: 31nMAssay Description:NOX4 inhibition is assessed utilizing HEK293 cells stably overexpressing human NOX4 (hNOX4), generating constitutively high levels of hydrogen peroxi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetNADPH oxidase 4(Human)
Alexandria University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 807819BDBM807819(US20260132136, Example 149)
Affinity DataIC50: 32nMAssay Description:NOX4 inhibition is assessed utilizing HEK293 cells stably overexpressing human NOX4 (hNOX4), generating constitutively high levels of hydrogen peroxi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetNADPH oxidase 4(Human)
Alexandria University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 807729BDBM807729(US20260132136, Example 59)
Affinity DataIC50: 32nMAssay Description:NOX4 inhibition is assessed utilizing HEK293 cells stably overexpressing human NOX4 (hNOX4), generating constitutively high levels of hydrogen peroxi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetNADPH oxidase 4(Human)
Alexandria University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 807747BDBM807747(US20260132136, Example 77)
Affinity DataIC50: 32nMAssay Description:NOX4 inhibition is assessed utilizing HEK293 cells stably overexpressing human NOX4 (hNOX4), generating constitutively high levels of hydrogen peroxi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetNADPH oxidase 4(Human)
Alexandria University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 807686BDBM807686(5-Ethynyl-3-(5-hydroxypyrazin-2-yl)-2-((4-(trifluo...)
Affinity DataIC50: 32nMAssay Description:NOX4 inhibition is assessed utilizing HEK293 cells stably overexpressing human NOX4 (hNOX4), generating constitutively high levels of hydrogen peroxi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetNADPH oxidase 4(Human)
Alexandria University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 807814BDBM807814(US20260132136, Example 144)
Affinity DataIC50: 32nMAssay Description:NOX4 inhibition is assessed utilizing HEK293 cells stably overexpressing human NOX4 (hNOX4), generating constitutively high levels of hydrogen peroxi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetNADPH oxidase 4(Human)
Alexandria University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 807737BDBM807737(US20260132136, Example 67)
Affinity DataIC50: 33nMAssay Description:NOX4 inhibition is assessed utilizing HEK293 cells stably overexpressing human NOX4 (hNOX4), generating constitutively high levels of hydrogen peroxi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetNADPH oxidase 4(Human)
Alexandria University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 794115BDBM794115(US20260055120, Example 56)
Affinity DataIC50: 33nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetNADPH oxidase 4(Human)
Alexandria University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 807724BDBM807724(US20260132136, Example 54)
Affinity DataIC50: 33nMAssay Description:NOX4 inhibition is assessed utilizing HEK293 cells stably overexpressing human NOX4 (hNOX4), generating constitutively high levels of hydrogen peroxi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetNADPH oxidase 4(Human)
Alexandria University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 794068BDBM794068(US20260055120, Example 9)
Affinity DataIC50: 34nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetNADPH oxidase 4(Human)
Alexandria University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 794079BDBM794079(US20260055120, Example 20)
Affinity DataIC50: 34nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetNADPH oxidase 4(Human)
Alexandria University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 807719BDBM807719(US20260132136, Example 49)
Affinity DataIC50: 35nMAssay Description:NOX4 inhibition is assessed utilizing HEK293 cells stably overexpressing human NOX4 (hNOX4), generating constitutively high levels of hydrogen peroxi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetNADPH oxidase 4(Human)
Alexandria University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 794137BDBM794137(5-((4-Chlorobenzyl)thio)-6-(5-hydroxypyrazin-2-yl)...)
Affinity DataIC50: 35nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetNADPH oxidase 4(Human)
Alexandria University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 807741BDBM807741(US20260132136, Example 71)
Affinity DataIC50: 35nMAssay Description:NOX4 inhibition is assessed utilizing HEK293 cells stably overexpressing human NOX4 (hNOX4), generating constitutively high levels of hydrogen peroxi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetNADPH oxidase 4(Human)
Alexandria University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 807730BDBM807730(US20260132136, Example 60)
Affinity DataIC50: 35nMAssay Description:NOX4 inhibition is assessed utilizing HEK293 cells stably overexpressing human NOX4 (hNOX4), generating constitutively high levels of hydrogen peroxi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetNADPH oxidase 4(Human)
Alexandria University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 807751BDBM807751(US20260132136, Example 81)
Affinity DataIC50: 36nMAssay Description:NOX4 inhibition is assessed utilizing HEK293 cells stably overexpressing human NOX4 (hNOX4), generating constitutively high levels of hydrogen peroxi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

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