Compile Data Set for Download or QSAR
Report error Found 218 Enz. Inhib. hit(s) with Target = 'Non-receptor tyrosine-protein kinase TYK2 [V731I]'
TargetNon-receptor tyrosine-protein kinase TYK2 [V731I](Human)
Nimbus Lakshmi

US Patent
LigandPNGBDBM399765(US10323036, Compound VIII-13 | US10793574, Compoun...)
Affinity DataKd: <0.100nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan assay (Dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [V731I](Human)
Nimbus Lakshmi

US Patent
LigandPNGBDBM399574(US10323036, Compound I-17 | US10793574, Compound I...)
Affinity DataKd: <0.100nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan assay (Dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [V731I](Human)
Nimbus Lakshmi

US Patent
LigandPNGBDBM399766(US10323036, Compound VIII-14 | US10793574, Compoun...)
Affinity DataKd: <0.100nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan assay (Dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [V731I](Human)
Nimbus Lakshmi

US Patent
LigandPNGBDBM399768(US10323036, Compound VIII-16 | US10793574, Compoun...)
Affinity DataKd: <0.100nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan assay (Dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [V731I](Human)
Nimbus Lakshmi

US Patent
LigandPNGBDBM399569(US10323036, Compound I-12 | US10793574, Compound I...)
Affinity DataKd: <0.100nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan assay (Dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [V731I](Human)
Nimbus Lakshmi

US Patent
LigandPNGBDBM399570(US10323036, Compound I-13 | US10793574, Compound I...)
Affinity DataKd: <0.100nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan assay (Dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [V731I](Human)
Nimbus Lakshmi

US Patent
LigandPNGBDBM399764(US10323036, Compound VIII-12 | US10793574, Compoun...)
Affinity DataKd: <0.100nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan assay (Dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [V731I](Human)
Nimbus Lakshmi

US Patent
LigandPNGBDBM399565(US10323036, Compound I-8 | US10793574, Compound I-...)
Affinity DataKd: <0.100nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan assay (Dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [V731I](Human)
Nimbus Lakshmi

US Patent
LigandPNGBDBM399566(US10323036, Compound I-9 | US10793574, Compound I-...)
Affinity DataKd: <0.100nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan assay (Dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [V731I](Human)
Nimbus Lakshmi

US Patent
LigandPNGBDBM399567(US10323036, Compound I-10 | US10793574, Compound I...)
Affinity DataKd: <0.100nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan assay (Dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [V731I](Human)
Nimbus Lakshmi

US Patent
LigandPNGBDBM399717(US10323036, Compound I-201 | US10793574, Compound ...)
Affinity DataKd: <0.100nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan assay (Dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [V731I](Human)
Nimbus Lakshmi

US Patent
LigandPNGBDBM399558(US10323036, Compound I-100 | US10323036, Compound ...)
Affinity DataKd: <0.100nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan assay (Dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [V731I](Human)
Nimbus Lakshmi

US Patent
LigandPNGBDBM399587(US10323036, Compound I-31 | US10793574, Compound I...)
Affinity DataKd: <0.100nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan assay (Dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [V731I](Human)
Nimbus Lakshmi

US Patent
LigandPNGBDBM399773(US10323036, Compound XVI-4 | US10793574, Compound ...)
Affinity DataKd: <0.100nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan assay (Dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [V731I](Human)
Nimbus Lakshmi

US Patent
LigandPNGBDBM399769(US10323036, Compound VIII-17 | US10793574, Compoun...)
Affinity DataKd: <0.100nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan assay (Dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [V731I](Human)
Nimbus Lakshmi

US Patent
LigandPNGBDBM399730(US10323036, Compound I-217 | US10793574, Compound ...)
Affinity DataKd: <0.100nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan assay (Dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [V731I](Human)
Nimbus Lakshmi

US Patent
LigandPNGBDBM399731(US10323036, Compound I-218 | US10793574, Compound ...)
Affinity DataKd: <0.100nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan assay (Dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [V731I](Human)
Nimbus Lakshmi

US Patent
LigandPNGBDBM399668(US10323036, Compound I-112 | US10793574, Compound ...)
Affinity DataKd: <0.100nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan assay (Dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [V731I](Human)
Nimbus Lakshmi

US Patent
LigandPNGBDBM399558(US10323036, Compound I-100 | US10323036, Compound ...)
Affinity DataKd: <0.100nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan assay (Dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [V731I](Human)
Nimbus Lakshmi

US Patent
LigandPNGBDBM399618(US10323036, Compound I-62 | US10793574, Compound I...)
Affinity DataKd: <0.100nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan assay (Dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [V731I](Human)
Nimbus Lakshmi

US Patent
LigandPNGBDBM399620(US10323036, Compound I-64 | US10793574, Compound I...)
Affinity DataKd: <0.100nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan assay (Dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [V731I](Human)
Nimbus Lakshmi

US Patent
LigandPNGBDBM399613(US10323036, Compound I-57 | US10793574, Compound I...)
Affinity DataKd: <0.100nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan assay (Dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [V731I](Human)
Nimbus Lakshmi

US Patent
LigandPNGBDBM399741(US10323036, Compound I-229 | US10793574, Compound ...)
Affinity DataKd: <0.100nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan assay (Dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [V731I](Human)
Nimbus Lakshmi

US Patent
LigandPNGBDBM399744(US10323036, Compound I-232 | US10793574, Compound ...)
Affinity DataKd: <0.100nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan assay (Dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [V731I](Human)
Nimbus Lakshmi

US Patent
LigandPNGBDBM399737(US10323036, Compound I-225 | US10793574, Compound ...)
Affinity DataKd: <0.100nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan assay (Dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [V731I](Human)
Nimbus Lakshmi

US Patent
LigandPNGBDBM399739(US10323036, Compound I-227 | US10793574, Compound ...)
Affinity DataKd: <0.100nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan assay (Dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [V731I](Human)
Nimbus Lakshmi

US Patent
LigandPNGBDBM399573(US10323036, Compound I-16 | US10793574, Compound I...)
Affinity DataKd:  0.300nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan assay (Dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [V731I](Human)
Nimbus Lakshmi

US Patent
LigandPNGBDBM399701(US10323036, Compound I-145 | US10793574, Compound ...)
Affinity DataKd:  0.300nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan assay (Dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [V731I](Human)
Nimbus Lakshmi

US Patent
LigandPNGBDBM399575(US10323036, Compound I-18 | US10793574, Compound I...)
Affinity DataKd:  0.300nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan assay (Dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [V731I](Human)
Nimbus Lakshmi

US Patent
LigandPNGBDBM399698(US10323036, Compound I-142 | US10793574, Compound ...)
Affinity DataKd:  0.300nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan assay (Dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2 [V731I](Human)
Nimbus Lakshmi

US Patent
LigandPNGBDBM399571(US10323036, Compound I-14 | US10793574, Compound I...)
Affinity DataKd:  0.300nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan assay (Dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [V731I](Human)
Nimbus Lakshmi

US Patent
LigandPNGBDBM399699(US10323036, Compound I-143 | US10793574, Compound ...)
Affinity DataKd:  0.300nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan assay (Dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [V731I](Human)
Nimbus Lakshmi

US Patent
LigandPNGBDBM399572(US10323036, Compound I-15 | US10793574, Compound I...)
Affinity DataKd:  0.300nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan assay (Dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [V731I](Human)
Nimbus Lakshmi

US Patent
LigandPNGBDBM399700(US10323036, Compound I-144 | US10793574, Compound ...)
Affinity DataKd:  0.300nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan assay (Dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [V731I](Human)
Nimbus Lakshmi

US Patent
LigandPNGBDBM399695(US10323036, Compound I-139 | US10793574, Compound ...)
Affinity DataKd:  0.300nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan assay (Dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [V731I](Human)
Nimbus Lakshmi

US Patent
LigandPNGBDBM399561(US10323036, Compound I-4 | US10793574, Compound I-...)
Affinity DataKd:  0.300nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan assay (Dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [V731I](Human)
Nimbus Lakshmi

US Patent
LigandPNGBDBM399689(US10323036, Compound I-133 | US10793574, Compound ...)
Affinity DataKd:  0.300nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan assay (Dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [V731I](Human)
Nimbus Lakshmi

US Patent
LigandPNGBDBM399690(US10323036, Compound I-134 | US10793574, Compound ...)
Affinity DataKd:  0.300nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan assay (Dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [V731I](Human)
Nimbus Lakshmi

US Patent
LigandPNGBDBM399585(US10323036, Compound I-29 | US10793574, Compound I...)
Affinity DataKd:  0.300nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan assay (Dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [V731I](Human)
Nimbus Lakshmi

US Patent
LigandPNGBDBM399715(US10323036, Compound I-198 | US10793574, Compound ...)
Affinity DataKd:  0.300nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan assay (Dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [V731I](Human)
Nimbus Lakshmi

US Patent
LigandPNGBDBM399716(US10323036, Compound I-199 | US10793574, Compound ...)
Affinity DataKd:  0.300nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan assay (Dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [V731I](Human)
Nimbus Lakshmi

US Patent
LigandPNGBDBM399581(US10323036, Compound I-24 | US10793574, Compound I...)
Affinity DataKd:  0.300nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan assay (Dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [V731I](Human)
Nimbus Lakshmi

US Patent
LigandPNGBDBM399582(US10323036, Compound I-25 | US10793574, Compound I...)
Affinity DataKd:  0.300nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan assay (Dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [V731I](Human)
Nimbus Lakshmi

US Patent
LigandPNGBDBM399712(US10323036, Compound I-182 | US10793574, Compound ...)
Affinity DataKd:  0.300nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan assay (Dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [V731I](Human)
Nimbus Lakshmi

US Patent
LigandPNGBDBM399577(US10323036, Compound I-20 | US10793574, Compound I...)
Affinity DataKd:  0.300nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan assay (Dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [V731I](Human)
Nimbus Lakshmi

US Patent
LigandPNGBDBM399578(US10323036, Compound I-21 | US10793574, Compound I...)
Affinity DataKd:  0.300nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan assay (Dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [V731I](Human)
Nimbus Lakshmi

US Patent
LigandPNGBDBM399733(US10323036, Compound I-220 | US10793574, Compound ...)
Affinity DataKd:  0.300nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan assay (Dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [V731I](Human)
Nimbus Lakshmi

US Patent
LigandPNGBDBM399734(US10323036, Compound I-221 | US10793574, Compound ...)
Affinity DataKd:  0.300nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan assay (Dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [V731I](Human)
Nimbus Lakshmi

US Patent
LigandPNGBDBM399729(US10323036, Compound I-216 | US10793574, Compound ...)
Affinity DataKd:  0.300nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan assay (Dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2 [V731I](Human)
Nimbus Lakshmi

US Patent
LigandPNGBDBM399732(US10323036, Compound I-219 | US10793574, Compound ...)
Affinity DataKd:  0.300nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan assay (Dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
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