Compile Data Set for Download or QSAR
Report error Found 956 Enz. Inhib. hit(s) with Target = 'P2X purinoceptor 2/3'
TargetP2X purinoceptor 2/3(Human)
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50594498BDBM50594498(CHEMBL4583478)
Affinity DataIC50: 8.30nMAssay Description:Agonist activity at human P2X2R/P2X3R expressing CHO cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetP2X purinoceptor 2/3(Human)
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 86478BDBM86478(A-317491)
Affinity DataKi:  9nMAssay Description:Antagonist activity at human P2X2/3 expressed in human1321N1 cells assessed as inhibition of alpha,beta-methylene-ATP-stimulated Ca2+ influx preincub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetP2X purinoceptor 2/3(Human)
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 86478BDBM86478(A-317491)
Affinity DataKi:  9nMAssay Description:Antagonist activity at human P2X2/3 expressed in human1321N1 cells assessed as inhibition of alpha,beta-methylene-ATP-stimulated Ca2+ influx preincub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetP2X purinoceptor 2/3(Human)
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 320093BDBM320093(US10174016, Example 260 | 3-(5-ethyl-1,3- thiazol-...)
Affinity DataIC50: 14nMAssay Description:A fluorescent imaging plate reader (FLEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

TargetP2X purinoceptor 2/3(Human)
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 320093BDBM320093(US10174016, Example 260 | 3-(5-ethyl-1,3- thiazol-...)
Affinity DataIC50: 14nMAssay Description:A fluorescent imaging plate reader (FILEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2020
Entry Details
US Patent

TargetP2X purinoceptor 2/3(Human)
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 319936BDBM319936(US10174016, Example 103 | 3-[(2- Methylpyridin- 4-...)
Affinity DataIC50: 14nMAssay Description:A fluorescent imaging plate reader (FLEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

TargetP2X purinoceptor 2/3(Human)
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 319936BDBM319936(US10174016, Example 103 | 3-[(2- Methylpyridin- 4-...)
Affinity DataIC50: 14nMAssay Description:A fluorescent imaging plate reader (FILEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2020
Entry Details
US Patent

TargetP2X purinoceptor 2/3(Human)
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 319933BDBM319933(US10174016, Example 100 | N-[(1R)-1-(6- Methyl- py...)
Affinity DataIC50: 16nMAssay Description:A fluorescent imaging plate reader (FLEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

TargetP2X purinoceptor 2/3(Human)
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 319933BDBM319933(US10174016, Example 100 | N-[(1R)-1-(6- Methyl- py...)
Affinity DataIC50: 16nMAssay Description:A fluorescent imaging plate reader (FILEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2020
Entry Details
US Patent

TargetP2X purinoceptor 2/3(Human)
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 319940BDBM319940(US10174016, Example 107 | N-[(1R)-1-(6- Methylpyri...)
Affinity DataIC50: 17nMAssay Description:A fluorescent imaging plate reader (FILEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2020
Entry Details
US Patent

TargetP2X purinoceptor 2/3(Human)
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 319940BDBM319940(US10174016, Example 107 | N-[(1R)-1-(6- Methylpyri...)
Affinity DataIC50: 17nMAssay Description:A fluorescent imaging plate reader (FLEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

TargetP2X purinoceptor 2/3(Human)
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 319931BDBM319931(US10174016, Example 98 | 3-(5-Methyl- 1,3-thiazol-...)
Affinity DataIC50: 19nMAssay Description:A fluorescent imaging plate reader (FILEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2020
Entry Details
US Patent

TargetP2X purinoceptor 2/3(Human)
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 319931BDBM319931(US10174016, Example 98 | 3-(5-Methyl- 1,3-thiazol-...)
Affinity DataIC50: 19nMAssay Description:A fluorescent imaging plate reader (FLEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

TargetP2X purinoceptor 2/3(Human)
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 320075BDBM320075(US10174016, Example 242 | 3-(5-ethyl-1,3- thiazol-...)
Affinity DataIC50: 22nMAssay Description:A fluorescent imaging plate reader (FILEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2020
Entry Details
US Patent

TargetP2X purinoceptor 2/3(Human)
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 320075BDBM320075(US10174016, Example 242 | 3-(5-ethyl-1,3- thiazol-...)
Affinity DataIC50: 22nMAssay Description:A fluorescent imaging plate reader (FLEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

TargetP2X purinoceptor 2/3(Human)
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 320102BDBM320102(US10174016, Example 269 | 3-(5-ethyl-1,3- thiazol-...)
Affinity DataIC50: 23nMAssay Description:A fluorescent imaging plate reader (FLEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

TargetP2X purinoceptor 2/3(Human)
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 320111BDBM320111(US10174016, Example 278 | 3-(5-ethyl-1,3- thiazol-...)
Affinity DataIC50: 23nMAssay Description:A fluorescent imaging plate reader (FILEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2020
Entry Details
US Patent

TargetP2X purinoceptor 2/3(Human)
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 319958BDBM319958(US10174016, Example 125 | 3-(5-Ethyl-1,3-thiazol-2...)
Affinity DataIC50: 27nMAssay Description:A fluorescent imaging plate reader (FLEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

TargetP2X purinoceptor 2/3(Human)
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 319932BDBM319932(US10174016, Example 99 | N-[(1R)-1-(6- Methyl- pyr...)
Affinity DataIC50: 27nMAssay Description:A fluorescent imaging plate reader (FILEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2020
Entry Details
US Patent

TargetP2X purinoceptor 2/3(Human)
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 320137BDBM320137(US10174016, Example 304 | 3-{[1-(2,2- difluoroethy...)
Affinity DataIC50: 27nMAssay Description:A fluorescent imaging plate reader (FLEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

TargetP2X purinoceptor 2/3(Human)
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 320137BDBM320137(US10174016, Example 304 | 3-{[1-(2,2- difluoroethy...)
Affinity DataIC50: 27nMAssay Description:A fluorescent imaging plate reader (FILEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2020
Entry Details
US Patent

TargetP2X purinoceptor 2/3(Human)
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 319932BDBM319932(US10174016, Example 99 | N-[(1R)-1-(6- Methyl- pyr...)
Affinity DataIC50: 27nMAssay Description:A fluorescent imaging plate reader (FLEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

TargetP2X purinoceptor 2/3(Human)
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 319958BDBM319958(US10174016, Example 125 | 3-(5-Ethyl-1,3-thiazol-2...)
Affinity DataIC50: 27nMAssay Description:A fluorescent imaging plate reader (FILEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2020
Entry Details
US Patent

TargetP2X purinoceptor 2/3(Human)
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 320217BDBM320217(US10174016, Example 384 | US10174016, Example 385 ...)
Affinity DataIC50: 28nMAssay Description:A fluorescent imaging plate reader (FILEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2020
Entry Details
US Patent

TargetP2X purinoceptor 2/3(Human)
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 322574BDBM322574(US10183937, Example 385 | US10202369, Example 385)
Affinity DataIC50: 28nMAssay Description:A fluorescent imaging plate reader (FLEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

TargetP2X purinoceptor 2/3(Human)
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 319962BDBM319962(US10174016, Example 129 | 3-(5-Ethyl-1,3-thiazol-2...)
Affinity DataIC50: 33nMAssay Description:A fluorescent imaging plate reader (FILEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2020
Entry Details
US Patent

TargetP2X purinoceptor 2/3(Human)
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 319962BDBM319962(US10174016, Example 129 | 3-(5-Ethyl-1,3-thiazol-2...)
Affinity DataIC50: 33nMAssay Description:A fluorescent imaging plate reader (FLEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

TargetP2X purinoceptor 2/3(Human)
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 319914BDBM319914(US10174016, Example 81 | N-[1-(5- Chloro-3- fluoro...)
Affinity DataIC50: 34nMAssay Description:A fluorescent imaging plate reader (FILEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2020
Entry Details
US Patent

TargetP2X purinoceptor 2/3(Human)
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 319914BDBM319914(US10174016, Example 81 | N-[1-(5- Chloro-3- fluoro...)
Affinity DataIC50: 34nMAssay Description:A fluorescent imaging plate reader (FLEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

TargetP2X purinoceptor 2/3(Human)
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 320102BDBM320102(US10174016, Example 269 | 3-(5-ethyl-1,3- thiazol-...)
Affinity DataIC50: 35nMAssay Description:A fluorescent imaging plate reader (FLEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

TargetP2X purinoceptor 2/3(Human)
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 320144BDBM320144(US10174016, Example 311 | N-[(1R)-1-(6- methylpyri...)
Affinity DataIC50: 35nMAssay Description:A fluorescent imaging plate reader (FLEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

TargetP2X purinoceptor 2/3(Human)
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 320216BDBM320216(3-{[4,4- difluoro-1- methylpiperidin- 3-yl]methoxy...)
Affinity DataIC50: 35nMAssay Description:A fluorescent imaging plate reader (FLEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

TargetP2X purinoceptor 2/3(Human)
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 320144BDBM320144(US10174016, Example 311 | N-[(1R)-1-(6- methylpyri...)
Affinity DataIC50: 35nMAssay Description:A fluorescent imaging plate reader (FILEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2020
Entry Details
US Patent

TargetP2X purinoceptor 2/3(Human)
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 320216BDBM320216(3-{[4,4- difluoro-1- methylpiperidin- 3-yl]methoxy...)
Affinity DataIC50: 35nMAssay Description:A fluorescent imaging plate reader (FILEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2020
Entry Details
US Patent

TargetP2X purinoceptor 2/3(Human)
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 320073BDBM320073(US10174016, Example 240 | 3-(5-ethyl-1,3- thiazol-...)
Affinity DataIC50: 35nMAssay Description:A fluorescent imaging plate reader (FLEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

TargetP2X purinoceptor 2/3(Human)
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 320073BDBM320073(US10174016, Example 240 | 3-(5-ethyl-1,3- thiazol-...)
Affinity DataIC50: 35nMAssay Description:A fluorescent imaging plate reader (FILEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2020
Entry Details
US Patent

TargetP2X purinoceptor 2/3(Human)
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 320111BDBM320111(US10174016, Example 278 | 3-(5-ethyl-1,3- thiazol-...)
Affinity DataIC50: 35nMAssay Description:A fluorescent imaging plate reader (FILEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2020
Entry Details
US Patent

TargetP2X purinoceptor 2/3(Human)
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 319918BDBM319918(US10174016, Example 85 | 3-(5-Methyl- 1,3-thiazol-...)
Affinity DataIC50: 36nMAssay Description:A fluorescent imaging plate reader (FLEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

TargetP2X purinoceptor 2/3(Human)
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 319918BDBM319918(US10174016, Example 85 | 3-(5-Methyl- 1,3-thiazol-...)
Affinity DataIC50: 36nMAssay Description:A fluorescent imaging plate reader (FILEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2020
Entry Details
US Patent

TargetP2X purinoceptor 2/3(Human)
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 320084BDBM320084(US10174016, Example 251 | 3-(5-ethyl-1,3- thiazol-...)
Affinity DataIC50: 38nMAssay Description:A fluorescent imaging plate reader (FILEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2020
Entry Details
US Patent

TargetP2X purinoceptor 2/3(Human)
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 320136BDBM320136(US10174016, Example 303 | 3-(5-methyl-1,3- thiazol...)
Affinity DataIC50: 38nMAssay Description:A fluorescent imaging plate reader (FLEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

TargetP2X purinoceptor 2/3(Human)
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 319839BDBM319839(US10174016, Example 6 | N-[1-(5-Chloro-3-fluoropyr...)
Affinity DataIC50: 38nMAssay Description:A fluorescent imaging plate reader (FLEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

TargetP2X purinoceptor 2/3(Human)
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 320091BDBM320091(US10174016, Example 258 | 3-(5-ethyl-1,3- thiazol-...)
Affinity DataIC50: 38nMAssay Description:A fluorescent imaging plate reader (FILEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2020
Entry Details
US Patent

TargetP2X purinoceptor 2/3(Human)
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 320136BDBM320136(US10174016, Example 303 | 3-(5-methyl-1,3- thiazol...)
Affinity DataIC50: 38nMAssay Description:A fluorescent imaging plate reader (FILEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2020
Entry Details
US Patent

TargetP2X purinoceptor 2/3(Human)
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 320084BDBM320084(US10174016, Example 251 | 3-(5-ethyl-1,3- thiazol-...)
Affinity DataIC50: 38nMAssay Description:A fluorescent imaging plate reader (FLEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

TargetP2X purinoceptor 2/3(Human)
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 320091BDBM320091(US10174016, Example 258 | 3-(5-ethyl-1,3- thiazol-...)
Affinity DataIC50: 38nMAssay Description:A fluorescent imaging plate reader (FLEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

TargetP2X purinoceptor 2/3(Human)
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 319839BDBM319839(US10174016, Example 6 | N-[1-(5-Chloro-3-fluoropyr...)
Affinity DataIC50: 38nMAssay Description:A fluorescent imaging plate reader (FILEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2020
Entry Details
US Patent

TargetP2X purinoceptor 2/3(Human)
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 319938BDBM319938(US10174016, Example 105 | 3-[(2- Methylpyridin- 4-...)
Affinity DataIC50: 39nMAssay Description:A fluorescent imaging plate reader (FILEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2020
Entry Details
US Patent

TargetP2X purinoceptor 2/3(Human)
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 319938BDBM319938(US10174016, Example 105 | 3-[(2- Methylpyridin- 4-...)
Affinity DataIC50: 39nMAssay Description:A fluorescent imaging plate reader (FLEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

TargetP2X purinoceptor 2/3(Human)
European Institute For Molecular Imaging (Eimi)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 656967BDBM656967(tert-butyl 2-(2- amino-5-((2- bromo-5- isopropylpy...)
Affinity DataIC50: 40nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2024
Entry Details
US Patent

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