Compile Data Set for Download or QSAR
Report error Found 11 Enz. Inhib. hit(s) with Target = 'Plasminogen activator inhibitor 1/Tissue-type plasminogen activator'
TargetPlasminogen activator inhibitor 1/Tissue-type plasminogen activator(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 264610BDBM264610(US9718760, C165)
Affinity DataIC50: 510nMT: 2°CAssay Description:PAI-1 inhibitor compounds were dissolved in DMSO to a final concentration of (10-50 mM), depending upon solubility. Compounds were then diluted in ph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2018
Entry Details
US Patent

TargetPlasminogen activator inhibitor 1/Tissue-type plasminogen activator(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 264609BDBM264609(US9718760, C163)
Affinity DataIC50: 611nMT: 2°CAssay Description:PAI-1 inhibitor compounds were dissolved in DMSO to a final concentration of (10-50 mM), depending upon solubility. Compounds were then diluted in ph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2018
Entry Details
US Patent

TargetPlasminogen activator inhibitor 1/Tissue-type plasminogen activator(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 264613BDBM264613(US9718760, C157)
Affinity DataIC50: 980nMT: 2°CAssay Description:PAI-1 inhibitor compounds were dissolved in DMSO to a final concentration of (10-50 mM), depending upon solubility. Compounds were then diluted in ph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2018
Entry Details
US Patent

TargetPlasminogen activator inhibitor 1/Tissue-type plasminogen activator(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 264607BDBM264607(US9718760, C153)
Affinity DataIC50: 1.02E+3nMT: 2°CAssay Description:PAI-1 inhibitor compounds were dissolved in DMSO to a final concentration of (10-50 mM), depending upon solubility. Compounds were then diluted in ph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2018
Entry Details
US Patent

TargetPlasminogen activator inhibitor 1/Tissue-type plasminogen activator(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 264614BDBM264614(US9718760, C158)
Affinity DataIC50: 1.44E+3nMT: 2°CAssay Description:PAI-1 inhibitor compounds were dissolved in DMSO to a final concentration of (10-50 mM), depending upon solubility. Compounds were then diluted in ph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2018
Entry Details
US Patent

TargetPlasminogen activator inhibitor 1/Tissue-type plasminogen activator(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 264597BDBM264597(US9718760, C152)
Affinity DataIC50: 1.71E+3nMT: 2°CAssay Description:PAI-1 inhibitor compounds were dissolved in DMSO to a final concentration of (10-50 mM), depending upon solubility. Compounds were then diluted in ph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2018
Entry Details
US Patent

TargetPlasminogen activator inhibitor 1/Tissue-type plasminogen activator(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 264648BDBM264648(US9718760, C161)
Affinity DataIC50: 2.21E+3nMT: 2°CAssay Description:PAI-1 inhibitor compounds were dissolved in DMSO to a final concentration of (10-50 mM), depending upon solubility. Compounds were then diluted in ph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2018
Entry Details
US Patent

TargetPlasminogen activator inhibitor 1/Tissue-type plasminogen activator(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 264608BDBM264608(US9718760, C162)
Affinity DataIC50: 7.59E+3nMT: 2°CAssay Description:PAI-1 inhibitor compounds were dissolved in DMSO to a final concentration of (10-50 mM), depending upon solubility. Compounds were then diluted in ph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2018
Entry Details
US Patent

TargetPlasminogen activator inhibitor 1/Tissue-type plasminogen activator(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 264598BDBM264598(US9718760, C155)
Affinity DataIC50: 3.48E+4nMT: 2°CAssay Description:PAI-1 inhibitor compounds were dissolved in DMSO to a final concentration of (10-50 mM), depending upon solubility. Compounds were then diluted in ph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2018
Entry Details
US Patent

TargetPlasminogen activator inhibitor 1/Tissue-type plasminogen activator(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 264627BDBM264627(US9718760, C160)
Affinity DataIC50: 5.82E+4nMT: 2°CAssay Description:PAI-1 inhibitor compounds were dissolved in DMSO to a final concentration of (10-50 mM), depending upon solubility. Compounds were then diluted in ph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2018
Entry Details
US Patent

TargetPlasminogen activator inhibitor 1/Tissue-type plasminogen activator(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 264647BDBM264647(US9718760, C156)
Affinity DataIC50: 5.81E+5nMT: 2°CAssay Description:PAI-1 inhibitor compounds were dissolved in DMSO to a final concentration of (10-50 mM), depending upon solubility. Compounds were then diluted in ph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2018
Entry Details
US Patent