Compile Data Set for Download or QSAR
Report error Found 1705 Enz. Inhib. hit(s) with Target = 'Platelet-activating factor receptor'
LigandChemical structure of BindingDB Monomer ID 50280478BDBM50280478(N-((S)-1-Ethoxymethyl-3-methyl-butyl)-4-(2-methyl-...)
Affinity DataIC50: 0.0150nMAssay Description:Antagonistic activity for inhibition of [3H]PAF receptor binding to washed human platelet membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 85035BDBM85035(bloodplatelet-activatingfactor | CAS_65154-06-5 | ...)
Affinity DataKi:  0.150nMAssay Description:Displacement of [3H]PAF from platelet activating factor receptor in human platelets after 3 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPlatelet-activating factor receptor(Guinea pig)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50062051BDBM50062051(1-Dimethylcarbamoyl-6-(4-fluoro-phenyl)-3-[4-(2-me...)
Affinity DataKi:  0.150nMAssay Description:Binding potency against Platelet activating factor (PAF) receptor using [3H]C18-PAF as radioligand on rabbit platelet membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-activating factor receptor(Guinea pig)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50062066BDBM50062066(3-[4-(2-Methyl-imidazo[4,5-c]pyridin-1-ylmethyl)-b...)
Affinity DataKi:  0.190nMAssay Description:Binding potency against Platelet activating factor (PAF) receptor using [3H]C18-PAF as radioligand on rabbit platelet membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50011635BDBM50011635(CHEMBL277701 | 1-{3-[4-(2-Chloro-phenyl)-9-methyl-...)
Affinity DataIC50: 0.200nMAssay Description:PAF-antagonist activity determined in dog platelets by PAF-binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 85035BDBM85035(bloodplatelet-activatingfactor | CAS_65154-06-5 | ...)
Affinity DataIC50: 0.280nMAssay Description:Displacement of [3H]PAF from platelet activating factor receptor in human platelets after 3 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandChemical structure of BindingDB Monomer ID 50011650BDBM50011650(CHEMBL20195 | 1-{3-[4-(2-Chloro-phenyl)-9-methyl-6...)
Affinity DataIC50: 0.300nMAssay Description:PAF-antagonist activity determined in dog platelets by PAF-binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-activating factor receptor(Guinea pig)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033236BDBM50033236(8,9-Dichloro-2-methyl-5-[4-(2-methyl-imidazo[4,5-c...)
Affinity DataIC50: 0.300nMAssay Description:In vitro antagonist activity against platelet activating factor (PAF) receptor, using washed rabbit plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2012
Entry Details Article
PubMed
TargetPlatelet-activating factor receptor(Guinea pig)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50286027BDBM50286027(6-(4-Fluoro-phenyl)-3-[[(Z)-hydroxyimino]-((R)-3-p...)
Affinity DataKi:  0.370nMAssay Description:Binding affinity for Platelet Activating Factor receptor using [3H]PAF in rabbit platelet membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetPlatelet-activating factor receptor(Guinea pig)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50048485BDBM50048485((S)-4-Methyl-2-{methyl-[4-(2-methyl-imidazo[4,5-c]...)
Affinity DataKi:  0.400nMAssay Description:The compound was evaluated for its binding affinity against PAF receptor in rabbit plateletMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50617206BDBM50617206(CHEMBL5439289)
Affinity DataIC50: 0.400nMAssay Description:Antagonist activity at human PAFR expressed in HEK293 cells assessed as inhibition of PAF C-16 ligand induced receptor activation preincubated for 90...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPlatelet-activating factor receptor(Guinea pig)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033242BDBM50033242(3-Cyclohexyl-6-[4-(2-methyl-imidazo[4,5-c]pyridin-...)
Affinity DataIC50: 0.400nMAssay Description:In vitro antagonist activity against platelet activating factor (PAF) receptor, using washed rabbit plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2012
Entry Details Article
PubMed
TargetPlatelet-activating factor receptor(Guinea pig)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50048485BDBM50048485((S)-4-Methyl-2-{methyl-[4-(2-methyl-imidazo[4,5-c]...)
Affinity DataKi:  0.400nMAssay Description:The compound was evaluated for its binding affinity against PAF receptor in rabbit plateletMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 552615BDBM552615(WO2022101377, Example 14)
Affinity DataIC50: 0.400nMAssay Description:USING AN ENDPOINT ASSAY HEK293 cells overexpressing human PAFR (produced in-house) are seeded into a Poly-D-Lysine coated 384 well white cell culture...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
WIPO WO2022101377

TargetPlatelet-activating factor receptor(Guinea pig)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033211BDBM50033211(7,8-Dichloro-4-[4-(2-methyl-imidazo[4,5-c]pyridin-...)
Affinity DataIC50: 0.5nMAssay Description:Antagonistic activity was tested against Platelet-Activating Factor-induced aggregation of rabbit washed platelets.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 552651BDBM552651(WO2022101377, Example 50)
Affinity DataIC50: 0.5nMAssay Description:USING AN ENDPOINT ASSAY HEK293 cells overexpressing human PAFR (produced in-house) are seeded into a Poly-D-Lysine coated 384 well white cell culture...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
WIPO WO2022101377

TargetPlatelet-activating factor receptor(Guinea pig)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004622BDBM50004622(CHEMBL106908 | 4-(2-Chloro-phenyl)-2-methyl-6-[4-(...)
Affinity DataIC50: 0.5nMAssay Description:In vitro inhibition of PAF-induced aggregation of rabbit washed platelets.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 552651BDBM552651(WO2022101377, Example 50)
Affinity DataIC50: 0.5nMAssay Description:Antagonist activity at human PAFR expressed in HEK293 cells assessed as inhibition of PAF C-16 ligand induced receptor activation preincubated for 90...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPlatelet-activating factor receptor(Guinea pig)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033257BDBM50033257(1,8-Dimethyl-5-[4-(2-methyl-imidazo[4,5-c]pyridin-...)
Affinity DataIC50: 0.5nMAssay Description:In vitro antagonist activity against platelet activating factor (PAF) receptor, using washed rabbit plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2012
Entry Details Article
PubMed
TargetPlatelet-activating factor receptor(Guinea pig)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033213BDBM50033213(7,8-Dichloro-1-methyl-4-[4-(2-methyl-imidazo[4,5-c...)
Affinity DataIC50: 0.5nMAssay Description:Antagonistic activity was tested against Platelet-Activating Factor-induced aggregation of rabbit washed platelets.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2012
Entry Details Article
PubMed
TargetPlatelet-activating factor receptor(Guinea pig)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033212BDBM50033212(7,8-Dichloro-4-[4-(2-methyl-imidazo[4,5-c]pyridin-...)
Affinity DataIC50: 0.5nMAssay Description:Antagonistic activity was tested against Platelet-Activating Factor-induced aggregation of rabbit washed platelets.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2012
Entry Details Article
PubMed
TargetPlatelet-activating factor receptor(Guinea pig)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50062069BDBM50062069(4-Methoxy-3-[4-(2-methyl-imidazo[4,5-c]pyridin-1-y...)
Affinity DataKi:  0.510nMAssay Description:Binding potency against Platelet activating factor (PAF) receptor using [3H]C18-PAF as radioligand on rabbit platelet membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-activating factor receptor(Guinea pig)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033223BDBM50033223(7,8-Dimethyl-4-[4-(2-methyl-imidazo[4,5-c]pyridin-...)
Affinity DataIC50: 0.600nMAssay Description:Antagonistic activity was tested against Platelet-Activating Factor-induced aggregation of rabbit washed platelets.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2012
Entry Details Article
PubMed
TargetPlatelet-activating factor receptor(Guinea pig)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033240BDBM50033240(1-Methyl-5-[4-(2-methyl-imidazo[4,5-c]pyridin-1-yl...)
Affinity DataIC50: 0.600nMAssay Description:In vitro antagonist activity against platelet activating factor (PAF) receptor, using washed rabbit plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2012
Entry Details Article
PubMed
TargetPlatelet-activating factor receptor(Guinea pig)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50038757BDBM50038757(6-Bromo-3-((R)-2-pyridin-3-yl-thiazolidine-4-carbo...)
Affinity DataKi:  0.600nMAssay Description:Antagonist activity against platelet activating factor (PAF) receptor in rabbit platelet membranes using [3H]C18-PAF as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50011611BDBM50011611(CHEMBL19640 | 1-{3-[4-(2-Chloro-phenyl)-9-methyl-6...)
Affinity DataIC50: 0.600nMAssay Description:PAF-antagonist activity determined in dog platelets by PAF-binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-activating factor receptor(Guinea pig)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033238BDBM50033238(3-(4-Chloro-phenyl)-1,8-dimethyl-5-[4-(2-methyl-im...)
Affinity DataIC50: 0.600nMAssay Description:In vitro antagonist activity against platelet activating factor (PAF) receptor, using washed rabbit plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2012
Entry Details Article
PubMed
TargetPlatelet-activating factor receptor(Guinea pig)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50062101BDBM50062101(4-Ethynyl-3-[3-fluoro-4-(2-methyl-imidazo[4,5-c]py...)
Affinity DataKi:  0.630nMAssay Description:Binding potency against Platelet activating factor (PAF) receptor using [3H]C18-PAF as radioligand on rabbit platelet membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-activating factor receptor(Guinea pig)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50062056BDBM50062056(1-Dimethylcarbamoyl-3-{2-[4-(2-methyl-imidazo[4,5-...)
Affinity DataKi:  0.630nMAssay Description:Binding potency against Platelet activating factor (PAF) receptor using [3H]C18-PAF as radioligand on rabbit platelet membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-activating factor receptor(Guinea pig)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50062061BDBM50062061(1-(3,3-Dimethyl-2-oxo-butyl)-3-[4-(2-methyl-imidaz...)
Affinity DataKi:  0.670nMAssay Description:Binding potency against Platelet activating factor (PAF) receptor using [3H]C18-PAF as radioligand on rabbit platelet membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-activating factor receptor(Guinea pig)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50285986BDBM50285986(2-[6-(4-Fluoro-phenyl)-3-(3-pyridin-3-yl-1H-pyrrol...)
Affinity DataKi:  0.700nMAssay Description:Tested in vitro for antagonistic activity to displace [3H]PAF from rabbit platelet membrane PAF receptorsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50011634BDBM50011634(CHEMBL19747 | 4-{3-[4-(2-Chloro-phenyl)-9-methyl-6...)
Affinity DataIC50: 0.700nMAssay Description:PAF-antagonist activity determined in dog platelets by PAF-binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 552674BDBM552674(WO2022101377, Example 73)
Affinity DataIC50: 0.700nMAssay Description:Antagonist activity at human PAFR expressed in HEK293 cells assessed as inhibition of PAF C-16 ligand induced receptor activation preincubated for 90...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50011623BDBM50011623(CHEMBL20019 | 2a-{3-[4-(2-Chloro-phenyl)-9-methyl-...)
Affinity DataIC50: 0.700nMAssay Description:PAF-antagonist activity determined in dog platelets by PAF-binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-activating factor receptor(Guinea pig)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033214BDBM50033214(7,8-Dimethyl-4-[4-(2-methyl-imidazo[4,5-c]pyridin-...)
Affinity DataIC50: 0.700nMAssay Description:Antagonistic activity was tested against Platelet-Activating Factor-induced aggregation of rabbit washed platelets.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 552674BDBM552674(WO2022101377, Example 73)
Affinity DataIC50: 0.700nMAssay Description:USING AN ENDPOINT ASSAY HEK293 cells overexpressing human PAFR (produced in-house) are seeded into a Poly-D-Lysine coated 384 well white cell culture...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
WIPO WO2022101377

TargetPlatelet-activating factor receptor(Guinea pig)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033264BDBM50033264(3-Cyclohexyl-1,8-dimethyl-5-[4-(2-methyl-imidazo[4...)
Affinity DataIC50: 0.700nMAssay Description:In vitro antagonist activity against platelet activating factor (PAF) receptor, using washed rabbit plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2012
Entry Details Article
PubMed
TargetPlatelet-activating factor receptor(Guinea pig)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50062045BDBM50062045(6-Benzofuran-2-yl-1-dimethylcarbamoyl-3-[4-(2-meth...)
Affinity DataKi:  0.780nMAssay Description:Binding potency against Platelet activating factor (PAF) receptor using [3H]C18-PAF as radioligand on rabbit platelet membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-activating factor receptor(Guinea pig)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033260BDBM50033260(3-Isobutoxymethyl-1,8-dimethyl-5-[4-(2-methyl-imid...)
Affinity DataIC50: 0.800nMAssay Description:In vitro antagonist activity against platelet activating factor (PAF) receptor, using washed rabbit plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2012
Entry Details Article
PubMed
TargetPlatelet-activating factor receptor(Guinea pig)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50038809BDBM50038809(3-((R)-2-Pyridin-3-yl-thiazolidine-4-carbonyl)-ind...)
Affinity DataKi:  0.800nMAssay Description:Antagonist activity against platelet activating factor (PAF) receptor in rabbit platelet membranes using [3H]C18-PAF as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetPlatelet-activating factor receptor(Guinea pig)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50062082BDBM50062082(4-Methyl-3-[4-(2-methyl-imidazo[4,5-c]pyridin-1-yl...)
Affinity DataKi:  0.820nMAssay Description:Binding potency against Platelet activating factor (PAF) receptor using [3H]C18-PAF as radioligand on rabbit platelet membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-activating factor receptor(Guinea pig)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50062113BDBM50062113(1-Dimethylcarbamoyl-3-[4-(2-methyl-imidazo[4,5-c]p...)
Affinity DataKi:  0.850nMAssay Description:Binding potency against Platelet activating factor (PAF) receptor using [3H]C18-PAF as radioligand on rabbit platelet membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-activating factor receptor(Guinea pig)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50062064BDBM50062064(1-Dimethylcarbamoyl-3-[4-(2-methyl-imidazo[4,5-c]p...)
Affinity DataKi:  0.860nMAssay Description:Binding potency against Platelet activating factor (PAF) receptor using [3H]C18-PAF as radioligand on rabbit platelet membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-activating factor receptor(Guinea pig)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50062092BDBM50062092((4,7-Dimethyl-1H-indol-3-yl)-[4-(2-methyl-imidazo[...)
Affinity DataKi:  0.870nMAssay Description:Binding potency against Platelet activating factor (PAF) receptor using [3H]C18-PAF as radioligand on rabbit platelet membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-activating factor receptor(Guinea pig)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033206BDBM50033206(7,8-Dichloro-4-[4-(2-methyl-imidazo[4,5-c]pyridin-...)
Affinity DataIC50: 0.900nMAssay Description:Antagonistic activity was tested against Platelet-Activating Factor-induced aggregation of rabbit washed platelets.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2012
Entry Details Article
PubMed
TargetPlatelet-activating factor receptor(Guinea pig)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50062106BDBM50062106(4-Chloro-3-[4-(2-methyl-imidazo[4,5-b]pyridin-1-yl...)
Affinity DataKi:  0.900nMAssay Description:Binding potency against Platelet activating factor (PAF) receptor using [3H]C18-PAF as radioligand on rabbit platelet membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-activating factor receptor(Guinea pig)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50062118BDBM50062118(4-Ethyl-3-[4-(2-methyl-imidazo[4,5-c]pyridin-1-ylm...)
Affinity DataKi:  0.910nMAssay Description:Binding potency against Platelet activating factor (PAF) receptor using [3H]C18-PAF as radioligand on rabbit platelet membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-activating factor receptor(Guinea pig)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50062048BDBM50062048(1-Dimethylcarbamoyl-3-[4-(2-methyl-benzoimidazol-1...)
Affinity DataKi:  0.920nMAssay Description:Binding potency against Platelet activating factor (PAF) receptor using [3H]C18-PAF as radioligand on rabbit platelet membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-activating factor receptor(Guinea pig)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50062098BDBM50062098(1-Dimethylcarbamoyl-3-[4-(2-methyl-imidazo[4,5-c]p...)
Affinity DataKi:  0.950nMAssay Description:Binding potency against Platelet activating factor (PAF) receptor using [3H]C18-PAF as radioligand on rabbit platelet membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50011653BDBM50011653(CHEMBL282883 | 2-{3-[4-(2-Chloro-phenyl)-9-methyl-...)
Affinity DataIC50: 1nMAssay Description:PAF-antagonist activity determined in dog platelets by PAF-binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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