Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with Target = 'Polyphenol oxidase 1 [N65D,S176D,K211T,P277A,P406L]'
TargetPolyphenol oxidase 1 [N65D,S176D,K211T,P277A,P406L](White button mushroom)
University of Technology Sydney

LigandChemical structure of BindingDB Monomer ID 173587BDBM173587((2E)-3-(3,5-dihydroxyphenyl)-1-(3-hydroxynaphthale...)
Affinity DataKi:  3.80E+3nM IC50: 1.04E+4nMpH: 6.8Assay Description:The mushroom tyrosinase inhibition activity of hydroxy naphthylchalcone compounds was measured using L-DOPA as substrate. The activity assay used 3 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetPolyphenol oxidase 1 [N65D,S176D,K211T,P277A,P406L](White button mushroom)
University of Technology Sydney

LigandChemical structure of BindingDB Monomer ID 173584BDBM173584((2E)-3-(2,4-dihydroxyphenyl)-1-(3-hydroxynaphthale...)
Affinity DataKi:  4.50E+3nM IC50: 1.44E+4nMpH: 6.8Assay Description:The mushroom tyrosinase inhibition activity of hydroxy naphthylchalcone compounds was measured using L-DOPA as substrate. The activity assay used 3 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetPolyphenol oxidase 1 [N65D,S176D,K211T,P277A,P406L](White button mushroom)
University of Technology Sydney

LigandChemical structure of BindingDB Monomer ID 173583BDBM173583((2E)-3-(2,5-dihydroxyphenyl)-1-(3-hydroxynaphthale...)
Affinity DataKi:  1.08E+4nM IC50: 2.04E+4nMpH: 6.8Assay Description:The mushroom tyrosinase inhibition activity of hydroxy naphthylchalcone compounds was measured using L-DOPA as substrate. The activity assay used 3 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetPolyphenol oxidase 1 [N65D,S176D,K211T,P277A,P406L](White button mushroom)
University of Technology Sydney

LigandChemical structure of BindingDB Monomer ID 173585BDBM173585((2E)-1-(3-hydroxynaphthalen-2-yl)-3-(2-hydroxy-4-n...)
Affinity DataKi:  1.12E+4nM IC50: 2.29E+4nMpH: 6.8Assay Description:The mushroom tyrosinase inhibition activity of hydroxy naphthylchalcone compounds was measured using L-DOPA as substrate. The activity assay used 3 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetPolyphenol oxidase 1 [N65D,S176D,K211T,P277A,P406L](White button mushroom)
University of Technology Sydney

LigandChemical structure of BindingDB Monomer ID 173586BDBM173586((2E)-1-(3-hydroxynaphthalen-2-yl)-3-(4-hydroxy-3-n...)
Affinity DataKi:  1.19E+4nM IC50: 2.56E+4nMpH: 6.8Assay Description:The mushroom tyrosinase inhibition activity of hydroxy naphthylchalcone compounds was measured using L-DOPA as substrate. The activity assay used 3 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetPolyphenol oxidase 1 [N65D,S176D,K211T,P277A,P406L](White button mushroom)
University of Technology Sydney

LigandChemical structure of BindingDB Monomer ID 50031467BDBM50031467(Kojic Acid | CHEMBL287556 | 5-HYDROXY-2-(HYDROXYME...)
Affinity DataKi:  1.22E+4nM IC50: 2.75E+4nMpH: 6.8Assay Description:The mushroom tyrosinase inhibition activity of hydroxy naphthylchalcone compounds was measured using L-DOPA as substrate. The activity assay used 3 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed