Compile Data Set for Download or QSAR
Report error Found 44 Enz. Inhib. hit(s) with Target = 'Probable C-C chemokine receptor type 3'
TargetProbable C-C chemokine receptor type 3(Mouse)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50209974BDBM50209974(1-((3S,4S)-4-(((S)-3-(4-fluorobenzyl)piperidin-1-y...)
Affinity DataIC50: 3.60nMAssay Description:Displacement of [125I]eotaxin from BALB/c mouse CCR3 expressed in CHO cells after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProbable C-C chemokine receptor type 3(Mouse)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50209974BDBM50209974(1-((3S,4S)-4-(((S)-3-(4-fluorobenzyl)piperidin-1-y...)
Affinity DataIC50: 7nMAssay Description:Antagonist activity at CCR3 assessed as eotaxin-induced chemotaxis in BALB/c mouse eosinophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProbable C-C chemokine receptor type 3(Mouse)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50163636BDBM50163636(1-((1R,2S)-2-(((S)-3-(4-fluorobenzyl)piperidin-1-y...)
Affinity DataIC50: 10nMAssay Description:Inhibition of eotaxin-induced chemotaxis of mouse eosinophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProbable C-C chemokine receptor type 3(Mouse)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50041150BDBM50041150(CHEMBL3355932)
Affinity DataKi:  10nMAssay Description:Displacement of [125J]-eotaxin-1 from mouse CCR3 transfected in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetProbable C-C chemokine receptor type 3(Mouse)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50041181BDBM50041181(CHEMBL3355939)
Affinity DataKi:  18nMAssay Description:Displacement of [125J]-eotaxin-1 from mouse CCR3 transfected in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetProbable C-C chemokine receptor type 3(Mouse)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50163634BDBM50163634(1-{(1R,2S)-2-[(S)-3-(4-Fluoro-benzyl)-piperidin-1-...)
Affinity DataIC50: 20nMAssay Description:Inhibition of eotaxin-induced chemotaxis of mouse eosinophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProbable C-C chemokine receptor type 3(Mouse)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50041185BDBM50041185(CHEMBL3355944)
Affinity DataKi:  24nMAssay Description:Displacement of [125J]-eotaxin-1 from mouse CCR3 transfected in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetProbable C-C chemokine receptor type 3(Mouse)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50231358BDBM50231358(1-{(1R,2S)-3-[(S)-3-(4-Fluoro-benzyl)-piperidin-1-...)
Affinity DataIC50: 31nMAssay Description:Antagonist activity at CCR3 receptor in mouse eosinophil assessed as as inhibition of chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetProbable C-C chemokine receptor type 3(Mouse)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50041174BDBM50041174(CHEMBL3355938)
Affinity DataKi:  37nMAssay Description:Displacement of [125J]-eotaxin-1 from mouse CCR3 transfected in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetProbable C-C chemokine receptor type 3(Mouse)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50209971BDBM50209971(1-((1R,2S)-2-(((S)-3-(4-fluorobenzyl)piperidin-1-y...)
Affinity DataIC50: 41nMAssay Description:Inhibition of eotaxin-induced chemotaxis of mouse eosinophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProbable C-C chemokine receptor type 3(Mouse)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50209971BDBM50209971(1-((1R,2S)-2-(((S)-3-(4-fluorobenzyl)piperidin-1-y...)
Affinity DataIC50: 41nMAssay Description:Antagonist activity at CCR3 assessed as eotaxin-induced chemotaxis in BALB/c mouse eosinophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProbable C-C chemokine receptor type 3(Mouse)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50041186BDBM50041186(CHEMBL3355945)
Affinity DataKi:  48nMAssay Description:Displacement of [125J]-eotaxin-1 from mouse CCR3 transfected in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetProbable C-C chemokine receptor type 3(Mouse)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50041182BDBM50041182(CHEMBL3355940)
Affinity DataKi:  52nMAssay Description:Displacement of [125J]-eotaxin-1 from mouse CCR3 transfected in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetProbable C-C chemokine receptor type 3(Mouse)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50209971BDBM50209971(1-((1R,2S)-2-(((S)-3-(4-fluorobenzyl)piperidin-1-y...)
Affinity DataIC50: 54nMAssay Description:Displacement of [125I]eotaxin from BALB/c mouse CCR3 expressed in CHO cells after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProbable C-C chemokine receptor type 3(Mouse)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50041158BDBM50041158(CHEMBL3355934)
Affinity DataKi:  62nMAssay Description:Displacement of [125J]-eotaxin-1 from mouse CCR3 transfected in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetProbable C-C chemokine receptor type 3(Mouse)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50041090BDBM50041090(CHEMBL3355964)
Affinity DataKi:  64nMAssay Description:Displacement of [125J]-eotaxin-1 from mouse CCR3 transfected in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetProbable C-C chemokine receptor type 3(Mouse)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50041157BDBM50041157(CHEMBL3355933)
Affinity DataKi:  65nMAssay Description:Displacement of [125J]-eotaxin-1 from mouse CCR3 transfected in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetProbable C-C chemokine receptor type 3(Mouse)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50041193BDBM50041193(CHEMBL3355954)
Affinity DataKi:  72nMAssay Description:Displacement of [125J]-eotaxin-1 from mouse CCR3 transfected in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetProbable C-C chemokine receptor type 3(Mouse)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50041191BDBM50041191(CHEMBL3355952)
Affinity DataKi:  74nMAssay Description:Displacement of [125J]-eotaxin-1 from mouse CCR3 transfected in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetProbable C-C chemokine receptor type 3(Mouse)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50041088BDBM50041088(CHEMBL3355962)
Affinity DataKi:  79nMAssay Description:Displacement of [125J]-eotaxin-1 from mouse CCR3 transfected in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetProbable C-C chemokine receptor type 3(Mouse)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50041201BDBM50041201(CHEMBL3355950)
Affinity DataKi:  85nMAssay Description:Displacement of [125J]-eotaxin-1 from mouse CCR3 transfected in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetProbable C-C chemokine receptor type 3(Mouse)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50041184BDBM50041184(CHEMBL3355943)
Affinity DataKi:  92nMAssay Description:Displacement of [125J]-eotaxin-1 from mouse CCR3 transfected in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetProbable C-C chemokine receptor type 3(Mouse)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50041198BDBM50041198(CHEMBL3355960)
Affinity DataKi:  110nMAssay Description:Displacement of [125J]-eotaxin-1 from mouse CCR3 transfected in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetProbable C-C chemokine receptor type 3(Mouse)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50041089BDBM50041089(CHEMBL3355963)
Affinity DataKi:  110nMAssay Description:Displacement of [125J]-eotaxin-1 from mouse CCR3 transfected in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetProbable C-C chemokine receptor type 3(Mouse)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50041192BDBM50041192(CHEMBL3355953)
Affinity DataKi:  120nMAssay Description:Displacement of [125J]-eotaxin-1 from mouse CCR3 transfected in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetProbable C-C chemokine receptor type 3(Mouse)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50041166BDBM50041166(CHEMBL3355936)
Affinity DataKi:  130nMAssay Description:Displacement of [125J]-eotaxin-1 from mouse CCR3 transfected in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetProbable C-C chemokine receptor type 3(Mouse)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50041163BDBM50041163(CHEMBL3355935)
Affinity DataKi:  210nMAssay Description:Displacement of [125J]-eotaxin-1 from mouse CCR3 transfected in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetProbable C-C chemokine receptor type 3(Mouse)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50041202BDBM50041202(CHEMBL3355957)
Affinity DataKi:  230nMAssay Description:Displacement of [125J]-eotaxin-1 from mouse CCR3 transfected in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetProbable C-C chemokine receptor type 3(Mouse)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50297171BDBM50297171(N-{(3R)-1-[(6-Fluoro-2-naphthyl)methyl]pyrrolidin-...)
Affinity DataIC50: 230nMAssay Description:Inhibition of mouse CCR3More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetProbable C-C chemokine receptor type 3(Mouse)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50041091BDBM50041091(CHEMBL3355965)
Affinity DataKi:  270nMAssay Description:Displacement of [125J]-eotaxin-1 from mouse CCR3 transfected in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetProbable C-C chemokine receptor type 3(Mouse)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50098624BDBM50098624(1-Cyclooct-1-enylmethyl-4-[(2,7-dichloro-9H-xanthe...)
Affinity DataIC50: 350nMAssay Description:Inhibitory activity against I-Eotaxin induced [Ca2+] response in mouse CCR3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProbable C-C chemokine receptor type 3(Mouse)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50041187BDBM50041187(CHEMBL3355946)
Affinity DataKi:  370nMAssay Description:Displacement of [125J]-eotaxin-1 from mouse CCR3 transfected in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetProbable C-C chemokine receptor type 3(Mouse)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50041200BDBM50041200(CHEMBL3355948)
Affinity DataKi:  380nMAssay Description:Displacement of [125J]-eotaxin-1 from mouse CCR3 transfected in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetProbable C-C chemokine receptor type 3(Mouse)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50041203BDBM50041203(CHEMBL3355942)
Affinity DataKi:  400nMAssay Description:Displacement of [125J]-eotaxin-1 from mouse CCR3 transfected in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetProbable C-C chemokine receptor type 3(Mouse)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50041199BDBM50041199(CHEMBL3355961)
Affinity DataKi:  410nMAssay Description:Displacement of [125J]-eotaxin-1 from mouse CCR3 transfected in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetProbable C-C chemokine receptor type 3(Mouse)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50098624BDBM50098624(1-Cyclooct-1-enylmethyl-4-[(2,7-dichloro-9H-xanthe...)
Affinity DataIC50: 460nMAssay Description:Inhibitory activity against I-Eotaxin alpha binding to mouse CCR3 receptorsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProbable C-C chemokine receptor type 3(Mouse)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50161407BDBM50161407([(3S,4S)-4-(3,4-Dichloro-benzyl)-3-hydroxymethyl-[...)
Affinity DataKi:  606nMAssay Description:In vitro binding affinity against mouse CC chemokine receptor 3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProbable C-C chemokine receptor type 3(Mouse)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50041195BDBM50041195(CHEMBL3355956)
Affinity DataKi:  630nMAssay Description:Displacement of [125J]-eotaxin-1 from mouse CCR3 transfected in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetProbable C-C chemokine receptor type 3(Mouse)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50041190BDBM50041190(CHEMBL3355951)
Affinity DataKi:  650nMAssay Description:Displacement of [125J]-eotaxin-1 from mouse CCR3 transfected in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetProbable C-C chemokine receptor type 3(Mouse)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50041092BDBM50041092(CHEMBL3355966)
Affinity DataKi:  660nMAssay Description:Displacement of [125J]-eotaxin-1 from mouse CCR3 transfected in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetProbable C-C chemokine receptor type 3(Mouse)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50041197BDBM50041197(CHEMBL3355959)
Affinity DataKi:  740nMAssay Description:Displacement of [125J]-eotaxin-1 from mouse CCR3 transfected in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetProbable C-C chemokine receptor type 3(Mouse)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50264212BDBM50264212(N-{(3-exo)-8-[(6-Fluoro-2-naphthyl)methyl]-8-azabi...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of mouse CCR3More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetProbable C-C chemokine receptor type 3(Mouse)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50041167BDBM50041167(CHEMBL3355937)
Affinity DataKi:  1.30E+3nMAssay Description:Displacement of [125J]-eotaxin-1 from mouse CCR3 transfected in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetProbable C-C chemokine receptor type 3(Mouse)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50041196BDBM50041196(CHEMBL3355958)
Affinity DataKi:  2.60E+3nMAssay Description:Displacement of [125J]-eotaxin-1 from mouse CCR3 transfected in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed