Compile Data Set for Download or QSAR
Report error Found 36 Enz. Inhib. hit(s) with Target = 'Prostaglandin G/H synthase 2 [E165G]'
TargetProstaglandin G/H synthase 2 [E165G](Human)
Beni-Suef University

LigandChemical structure of BindingDB Monomer ID 11639BDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 870nMAssay Description:The ability of the test compounds to inhibit ovine COX01 and human recombinant COX-2 was determined using an enzyme immuno assay (EIA) kit according ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2 [E165G](Human)
Beni-Suef University

LigandChemical structure of BindingDB Monomer ID 173509BDBM173509(3-(4-Ethoxyphenyl)-1-(4-methanesulfonylphenyl)-5-(...)
Affinity DataIC50: 970nMAssay Description:The ability of the test compounds to inhibit ovine COX01 and human recombinant COX-2 was determined using an enzyme immuno assay (EIA) kit according ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2 [E165G](Human)
Beni-Suef University

LigandChemical structure of BindingDB Monomer ID 173518BDBM173518(1-(4-Methanesulfonylphenyl)-3-(4-hydroxyphenyl)-5-...)
Affinity DataIC50: 970nMAssay Description:The ability of the test compounds to inhibit ovine COX01 and human recombinant COX-2 was determined using an enzyme immuno assay (EIA) kit according ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2 [E165G](Human)
Beni-Suef University

LigandChemical structure of BindingDB Monomer ID 173507BDBM173507(1-(4-Methanesulfonylphenyl)-3-(p-tolyl)-5-(4-trifl...)
Affinity DataIC50: 1.11E+3nMAssay Description:The ability of the test compounds to inhibit ovine COX01 and human recombinant COX-2 was determined using an enzyme immuno assay (EIA) kit according ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2 [E165G](Human)
Beni-Suef University

LigandChemical structure of BindingDB Monomer ID 11639BDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 1.33E+3nMAssay Description:The ability of the tested compounds to inhibit both COX-1 and COX-2 isozymes was measured using colorimetric COX (ovine) Inhibitor Screening Assay Ki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2 [E165G](Human)
Beni-Suef University

LigandChemical structure of BindingDB Monomer ID 173529BDBM173529(1-(4-Aminosulfonylphenyl)-3-(3,4-difluorophenyl)-5...)
Affinity DataIC50: 1.34E+3nMAssay Description:The ability of the test compounds to inhibit ovine COX01 and human recombinant COX-2 was determined using an enzyme immuno assay (EIA) kit according ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2 [E165G](Human)
Beni-Suef University

LigandChemical structure of BindingDB Monomer ID 173523BDBM173523(3-(3,4-Difluorophenyl)-1-(4-methanesulfonylphenyl)...)
Affinity DataIC50: 1.50E+3nMAssay Description:The ability of the test compounds to inhibit ovine COX01 and human recombinant COX-2 was determined using an enzyme immuno assay (EIA) kit according ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2 [E165G](Human)
Beni-Suef University

LigandChemical structure of BindingDB Monomer ID 173514BDBM173514(1-(4-Aminosulfonylphenyl)-3-(4-methoxyphenyl)-5-(4...)
Affinity DataIC50: 1.50E+3nMAssay Description:The ability of the test compounds to inhibit ovine COX01 and human recombinant COX-2 was determined using an enzyme immuno assay (EIA) kit according ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2 [E165G](Human)
Beni-Suef University

LigandChemical structure of BindingDB Monomer ID 173521BDBM173521(3-(4-ethoxyphenyl)-1-(4-methanesulfonylphenyl)-5-[...)
Affinity DataIC50: 1.71E+3nMAssay Description:The ability of the test compounds to inhibit ovine COX01 and human recombinant COX-2 was determined using an enzyme immuno assay (EIA) kit according ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2 [E165G](Human)
Beni-Suef University

LigandChemical structure of BindingDB Monomer ID 173512BDBM173512(1-(4-Aminosulfonylphenyl)-3-(4-hydroxyphenyl)-5-(4...)
Affinity DataIC50: 1.90E+3nMAssay Description:The ability of the test compounds to inhibit ovine COX01 and human recombinant COX-2 was determined using an enzyme immuno assay (EIA) kit according ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2 [E165G](Human)
Beni-Suef University

LigandChemical structure of BindingDB Monomer ID 175286BDBM175286(3-(4-Aminosulfonylphenylamino)-2-(4-fluorophenyl)-...)
Affinity DataIC50: 1.90E+3nMAssay Description:The ability of the tested compounds to inhibit both COX-1 and COX-2 isozymes was measured using colorimetric COX (ovine) Inhibitor Screening Assay Ki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2 [E165G](Human)
Beni-Suef University

LigandChemical structure of BindingDB Monomer ID 173516BDBM173516(1-(4-Aminosulfonylphenyl)-3-(4-fluorophenyl)-5-(4-...)
Affinity DataIC50: 2.17E+3nMAssay Description:The ability of the test compounds to inhibit ovine COX01 and human recombinant COX-2 was determined using an enzyme immuno assay (EIA) kit according ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2 [E165G](Human)
Beni-Suef University

LigandChemical structure of BindingDB Monomer ID 175285BDBM175285(3-(4-Aminosulfonylphenylamino)-2-(4-chlorophenyl)-...)
Affinity DataIC50: 2.30E+3nMAssay Description:The ability of the tested compounds to inhibit both COX-1 and COX-2 isozymes was measured using colorimetric COX (ovine) Inhibitor Screening Assay Ki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2 [E165G](Human)
Beni-Suef University

LigandChemical structure of BindingDB Monomer ID 173527BDBM173527(1-(4-Aminosulfonylphenyl)-3-(4-ethoxyphenyl)-5-(4-...)
Affinity DataIC50: 2.90E+3nMAssay Description:The ability of the test compounds to inhibit ovine COX01 and human recombinant COX-2 was determined using an enzyme immuno assay (EIA) kit according ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2 [E165G](Human)
Beni-Suef University

LigandChemical structure of BindingDB Monomer ID 173519BDBM173519(1-(4-Methanesulfonylphenyl)-3-(p-tolyl)-5-(4-trifl...)
Affinity DataIC50: 2.90E+3nMAssay Description:The ability of the test compounds to inhibit ovine COX01 and human recombinant COX-2 was determined using an enzyme immuno assay (EIA) kit according ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2 [E165G](Human)
Beni-Suef University

LigandChemical structure of BindingDB Monomer ID 173524BDBM173524(1-(4-Aminosulfonylphenyl)-3-(4-hydroxyphenyl)-5-(4...)
Affinity DataIC50: 3.10E+3nMAssay Description:The ability of the test compounds to inhibit ovine COX01 and human recombinant COX-2 was determined using an enzyme immuno assay (EIA) kit according ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2 [E165G](Human)
Beni-Suef University

LigandChemical structure of BindingDB Monomer ID 60580BDBM60580(3-(4-Aminosulfonylphenylamino)-5-methyl-2-(4-trifl...)
Affinity DataIC50: 3.40E+3nMAssay Description:The ability of the tested compounds to inhibit both COX-1 and COX-2 isozymes was measured using colorimetric COX (ovine) Inhibitor Screening Assay Ki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2 [E165G](Human)
Beni-Suef University

LigandChemical structure of BindingDB Monomer ID 173517BDBM173517(1-(4-Aminosulfonylphenyl)-3-(3,4-difluorophenyl)-5...)
Affinity DataIC50: 3.70E+3nMAssay Description:The ability of the test compounds to inhibit ovine COX01 and human recombinant COX-2 was determined using an enzyme immuno assay (EIA) kit according ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2 [E165G](Human)
Beni-Suef University

LigandChemical structure of BindingDB Monomer ID 173522BDBM173522(3-(4-Fluorophenyl)-1-(4-methanesulfonylphenyl)-5-(...)
Affinity DataIC50: 4.10E+3nMAssay Description:The ability of the test compounds to inhibit ovine COX01 and human recombinant COX-2 was determined using an enzyme immuno assay (EIA) kit according ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2 [E165G](Human)
Beni-Suef University

LigandChemical structure of BindingDB Monomer ID 173515BDBM173515(1-(4-Aminosulfonylphenyl)-3-(4-ethoxyphenyl)-5-(4-...)
Affinity DataIC50: 4.50E+3nMAssay Description:The ability of the test compounds to inhibit ovine COX01 and human recombinant COX-2 was determined using an enzyme immuno assay (EIA) kit according ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2 [E165G](Human)
Beni-Suef University

LigandChemical structure of BindingDB Monomer ID 175280BDBM175280(2-(4-(4-Nitrophenyl)thiazol-2-ylimino)thiazolidin-...)
Affinity DataIC50: 4.60E+3nMAssay Description:The ability of the tested compounds to inhibit both COX-1 and COX-2 isozymes was measured using colorimetric COX (ovine) Inhibitor Screening Assay Ki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2 [E165G](Human)
Beni-Suef University

LigandChemical structure of BindingDB Monomer ID 173510BDBM173510(3-(4-Fluorophenyl)-1-(4-Methanesulfonylphenyl)-5-(...)
Affinity DataIC50: 4.80E+3nMAssay Description:The ability of the test compounds to inhibit ovine COX01 and human recombinant COX-2 was determined using an enzyme immuno assay (EIA) kit according ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2 [E165G](Human)
Beni-Suef University

LigandChemical structure of BindingDB Monomer ID 175284BDBM175284(3-(4-Aminosulfonylphenylamino)-5-methyl-2-(4-methy...)
Affinity DataIC50: 4.80E+3nMAssay Description:The ability of the tested compounds to inhibit both COX-1 and COX-2 isozymes was measured using colorimetric COX (ovine) Inhibitor Screening Assay Ki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2 [E165G](Human)
Beni-Suef University

LigandChemical structure of BindingDB Monomer ID 175282BDBM175282(2-(4-(4-Methanesulfonamidophenyl)thiazol-2-ylimino...)
Affinity DataIC50: 5.30E+3nMAssay Description:The ability of the tested compounds to inhibit both COX-1 and COX-2 isozymes was measured using colorimetric COX (ovine) Inhibitor Screening Assay Ki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2 [E165G](Human)
Beni-Suef University

LigandChemical structure of BindingDB Monomer ID 173520BDBM173520(1-(4-methanesulfonylphenyl)-3-(4-methoxyphenyl)-5-...)
Affinity DataIC50: 5.40E+3nMAssay Description:The ability of the test compounds to inhibit ovine COX01 and human recombinant COX-2 was determined using an enzyme immuno assay (EIA) kit according ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2 [E165G](Human)
Beni-Suef University

LigandChemical structure of BindingDB Monomer ID 173525BDBM173525(1-(4-Aminosulfonylphenyl)-3-(p-tolyl)-5-(4-trifluo...)
Affinity DataIC50: 5.70E+3nMAssay Description:The ability of the test compounds to inhibit ovine COX01 and human recombinant COX-2 was determined using an enzyme immuno assay (EIA) kit according ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2 [E165G](Human)
Beni-Suef University

LigandChemical structure of BindingDB Monomer ID 175281BDBM175281(2-(4-(4-Isobutylphenyl)thiazol-2-ylimino)thiazolid...)
Affinity DataIC50: 6.10E+3nMAssay Description:The ability of the tested compounds to inhibit both COX-1 and COX-2 isozymes was measured using colorimetric COX (ovine) Inhibitor Screening Assay Ki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2 [E165G](Human)
Beni-Suef University

LigandChemical structure of BindingDB Monomer ID 173506BDBM173506(1-(4-Methanesulfonylphenyl)-3-(4-hydroxyphenyl)-5-...)
Affinity DataIC50: 6.70E+3nMAssay Description:The ability of the test compounds to inhibit ovine COX01 and human recombinant COX-2 was determined using an enzyme immuno assay (EIA) kit according ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2 [E165G](Human)
Beni-Suef University

LigandChemical structure of BindingDB Monomer ID 173528BDBM173528(1-(4-Aminosulfonylphenyl)-3-(4-fluorophenyl)-5-(4-...)
Affinity DataIC50: 6.80E+3nMAssay Description:The ability of the test compounds to inhibit ovine COX01 and human recombinant COX-2 was determined using an enzyme immuno assay (EIA) kit according ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2 [E165G](Human)
Beni-Suef University

LigandChemical structure of BindingDB Monomer ID 50009859BDBM50009859((RS)-ibuprofen | CHEMBL521 | 2-(4-isobutylphenyl)p...)
Affinity DataIC50: 7.20E+3nMAssay Description:The ability of the test compounds to inhibit ovine COX01 and human recombinant COX-2 was determined using an enzyme immuno assay (EIA) kit according ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 2 [E165G](Human)
Beni-Suef University

LigandChemical structure of BindingDB Monomer ID 173526BDBM173526(1-(4-Aminosulfonylphenyl)-3-(4-methoxyphenyl)-5-(4...)
Affinity DataIC50: 8.40E+3nMAssay Description:The ability of the test compounds to inhibit ovine COX01 and human recombinant COX-2 was determined using an enzyme immuno assay (EIA) kit according ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2 [E165G](Human)
Beni-Suef University

LigandChemical structure of BindingDB Monomer ID 173513BDBM173513(1-(4-Aminosulfonylphenyl)-3-(p-tolyl)-5-(4-trifluo...)
Affinity DataIC50: 8.70E+3nMAssay Description:The ability of the test compounds to inhibit ovine COX01 and human recombinant COX-2 was determined using an enzyme immuno assay (EIA) kit according ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2 [E165G](Human)
Beni-Suef University

LigandChemical structure of BindingDB Monomer ID 175283BDBM175283(3-(4-Aminosulfonylphenylamino)-5-methyl-2-phenyl-4...)
Affinity DataIC50: 8.70E+3nMAssay Description:The ability of the tested compounds to inhibit both COX-1 and COX-2 isozymes was measured using colorimetric COX (ovine) Inhibitor Screening Assay Ki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2 [E165G](Human)
Beni-Suef University

LigandChemical structure of BindingDB Monomer ID 173511BDBM173511(3-(3,4-Difluoroluorophenyl)-1-(4-methanesulfonylph...)
Affinity DataIC50: 9.40E+3nMAssay Description:The ability of the test compounds to inhibit ovine COX01 and human recombinant COX-2 was determined using an enzyme immuno assay (EIA) kit according ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2 [E165G](Human)
Beni-Suef University

LigandChemical structure of BindingDB Monomer ID 173508BDBM173508(1-(4-Methanesulfonylphenyl)-3-(4-methoxyphenyl)-5-...)
Affinity DataIC50: 1.08E+4nMAssay Description:The ability of the test compounds to inhibit ovine COX01 and human recombinant COX-2 was determined using an enzyme immuno assay (EIA) kit according ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2 [E165G](Human)
Beni-Suef University

LigandChemical structure of BindingDB Monomer ID 22360BDBM22360(2-(acetyloxy)benzoic acid | 2-(acetyloxy)benzoate ...)
Affinity DataIC50: 1.00E+5nMAssay Description:The ability of the test compounds to inhibit ovine COX01 and human recombinant COX-2 was determined using an enzyme immuno assay (EIA) kit according ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed