Compile Data Set for Download or QSAR
Report error Found 412 Enz. Inhib. hit(s) with Target = 'Protein disulfide-isomerase'
TargetProtein disulfide-isomerase A4(Human)
Academia Sinica

US Patent
LigandChemical structure of BindingDB Monomer ID 801826BDBM801826(methyl 4-methoxy-2-propiolamido-5-(3-(N-propioloyl...)
Affinity DataIC50: 0.300nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/31/2026
Entry Details
US Patent

TargetProtein disulfide-isomerase A4(Human)
Academia Sinica

US Patent
LigandChemical structure of BindingDB Monomer ID 801820BDBM801820(methyl 4-methoxy-2-propiolamido-5-(3-(N-(2-(3-(tri...)
Affinity DataIC50: 0.800nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/31/2026
Entry Details
US Patent

TargetProtein disulfide-isomerase A4(Human)
Academia Sinica

US Patent
LigandChemical structure of BindingDB Monomer ID 698938BDBM698938(2-amino-4-methoxy-5-propoxybenzoic propiolic anhyd...)
Affinity DataIC50: 1nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2026
Entry Details
US Patent

TargetProtein disulfide-isomerase A4(Human)
Academia Sinica

US Patent
LigandChemical structure of BindingDB Monomer ID 801821BDBM801821(methyl 4-methoxy-2-propiolamido-5-(3-(N-(2-(2-(tri...)
Affinity DataIC50: 1nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/31/2026
Entry Details
US Patent

TargetProtein disulfide-isomerase A4(Human)
Academia Sinica

US Patent
LigandChemical structure of BindingDB Monomer ID 801822BDBM801822(methyl 5-(3-(N-(2-(3-fluorophenyl)acetyl)propiolam...)
Affinity DataIC50: 1.20nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/31/2026
Entry Details
US Patent

TargetProtein disulfide-isomerase A4(Human)
Academia Sinica

US Patent
LigandChemical structure of BindingDB Monomer ID 801812BDBM801812(methyl 4-methoxy-5-(3-(N-(2-(2-methoxyphenyl)acety...)
Affinity DataIC50: 1.30nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/31/2026
Entry Details
US Patent

TargetProtein disulfide-isomerase A4(Human)
Academia Sinica

US Patent
LigandChemical structure of BindingDB Monomer ID 801824BDBM801824(methyl 4-methoxy-5-(3-(N-(2-(3-methoxyphenyl)acety...)
Affinity DataIC50: 1.40nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/31/2026
Entry Details
US Patent

TargetProtein disulfide-isomerase A4(Human)
Academia Sinica

US Patent
LigandChemical structure of BindingDB Monomer ID 801819BDBM801819(methyl 5-(3-(N-(2-(4-fluorophenyl)acetyl)propiolam...)
Affinity DataIC50: 1.40nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/31/2026
Entry Details
US Patent

TargetProtein disulfide-isomerase A4(Human)
Academia Sinica

US Patent
LigandChemical structure of BindingDB Monomer ID 801811BDBM801811(methyl 5-(3-(N-(2-(3-chlorophenyl)acetyl)propiolam...)
Affinity DataIC50: 1.60nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/31/2026
Entry Details
US Patent

TargetProtein disulfide-isomerase A4(Human)
Academia Sinica

US Patent
LigandChemical structure of BindingDB Monomer ID 801825BDBM801825(methyl 5-(3-(N-(2-(2-chlorophenyl)acetyl)propiolam...)
Affinity DataIC50: 1.60nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/31/2026
Entry Details
US Patent

TargetProtein disulfide-isomerase A4(Human)
Academia Sinica

US Patent
LigandChemical structure of BindingDB Monomer ID 801788BDBM801788(2-amino-4,5-dimethoxybenzoic propiolic anhydride |...)
Affinity DataIC50: 1.60nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/31/2026
Entry Details
US Patent

TargetProtein disulfide-isomerase A4(Human)
Academia Sinica

US Patent
LigandChemical structure of BindingDB Monomer ID 801810BDBM801810(methyl 5-(3-(N-(2-(2-fluorophenyl)acetyl)propiolam...)
Affinity DataIC50: 1.80nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/31/2026
Entry Details
US Patent

TargetProtein disulfide-isomerase A4(Human)
Academia Sinica

US Patent
LigandChemical structure of BindingDB Monomer ID 801809BDBM801809(methyl 4-methoxy-5-(3-(N-(2-phenylacetyl)propiolam...)
Affinity DataIC50: 1.90nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/31/2026
Entry Details
US Patent

TargetProtein disulfide-isomerase A4(Human)
Academia Sinica

US Patent
LigandChemical structure of BindingDB Monomer ID 801813BDBM801813(methyl 4-methoxy-5-(3-(N-(2-(4-methoxyphenyl)acety...)
Affinity DataIC50: 2.10nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/31/2026
Entry Details
US Patent

TargetProtein disulfide-isomerase A4(Human)
Academia Sinica

US Patent
LigandChemical structure of BindingDB Monomer ID 801801BDBM801801(methyl 5-(3-(4-fluoro-N-propioloylbenzamido)propox...)
Affinity DataIC50: 2.40nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/31/2026
Entry Details
US Patent

TargetProtein disulfide-isomerase A4(Human)
Academia Sinica

US Patent
LigandChemical structure of BindingDB Monomer ID 801823BDBM801823(methyl 4-methoxy-2-propiolamido-5-(3-(N-(2-(4-(tri...)
Affinity DataIC50: 2.40nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/31/2026
Entry Details
US Patent

TargetProtein disulfide-isomerase A4(Human)
Academia Sinica

US Patent
LigandChemical structure of BindingDB Monomer ID 801804BDBM801804(methyl 5-(3-(2,6-difluoro-N-propioloylbenzamido)pr...)
Affinity DataIC50: 2.40nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/31/2026
Entry Details
US Patent

TargetProtein disulfide-isomerase A4(Human)
Academia Sinica

US Patent
LigandChemical structure of BindingDB Monomer ID 801807BDBM801807(methyl 5-(3-(2,6-dimethoxy-N-propioloylbenzamido)p...)
Affinity DataIC50: 2.60nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/31/2026
Entry Details
US Patent

TargetProtein disulfide-isomerase A4(Human)
Academia Sinica

US Patent
LigandChemical structure of BindingDB Monomer ID 801802BDBM801802(methyl 5-(3-(3-fluoro-N-propioloylbenzamido)propox...)
Affinity DataIC50: 2.70nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/31/2026
Entry Details
US Patent

TargetProtein disulfide-isomerase A4(Human)
Academia Sinica

US Patent
LigandChemical structure of BindingDB Monomer ID 801798BDBM801798(methyl 4-methoxy-2-propiolamido-5-(2-(N-propioloyl...)
Affinity DataIC50: 3.30nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/31/2026
Entry Details
US Patent

TargetProtein disulfide-isomerase A4(Human)
Academia Sinica

US Patent
LigandChemical structure of BindingDB Monomer ID 801818BDBM801818(methyl 4-methoxy-2-propiolamido-5-(3-(N-(2-(3,4,5-...)
Affinity DataIC50: 3.30nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/31/2026
Entry Details
US Patent

TargetProtein disulfide-isomerase A4(Human)
Academia Sinica

US Patent
LigandChemical structure of BindingDB Monomer ID 801806BDBM801806(methyl 4-methoxy-5-(3-(3-methoxy-N-propioloylbenza...)
Affinity DataIC50: 3.30nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/31/2026
Entry Details
US Patent

TargetProtein disulfide-isomerase A4(Human)
Academia Sinica

US Patent
LigandChemical structure of BindingDB Monomer ID 801805BDBM801805(4-methoxy-5-(3-(4-methoxy-N-propioloylbenzamido)pr...)
Affinity DataIC50: 3.70nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/31/2026
Entry Details
US Patent

TargetProtein disulfide-isomerase A4(Human)
Academia Sinica

US Patent
LigandChemical structure of BindingDB Monomer ID 801800BDBM801800(4-methoxy-2-propiolamido-5-(3-(N-propioloylbenzami...)
Affinity DataIC50: 3.90nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/31/2026
Entry Details
US Patent

TargetProtein disulfide-isomerase A4(Human)
Academia Sinica

US Patent
LigandChemical structure of BindingDB Monomer ID 801803BDBM801803(methyl 5-(3-(2-fluoro-N-propioloylbenzamido)propox...)
Affinity DataIC50: 4.20nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/31/2026
Entry Details
US Patent

TargetProtein disulfide-isomerase A4(Human)
Academia Sinica

US Patent
LigandChemical structure of BindingDB Monomer ID 698937BDBM698937(2-amino-3,4,5-trimethoxybenzoic propiolic anhydrid...)
Affinity DataIC50: 4.30nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2026
Entry Details
US Patent

TargetProtein disulfide-isomerase A4(Human)
Academia Sinica

US Patent
LigandChemical structure of BindingDB Monomer ID 801796BDBM801796(methyl 5-(3-(1,3-dioxoisoindolin-2-yl)propoxy)-4-m...)
Affinity DataIC50: 4.30nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/31/2026
Entry Details
US Patent

TargetProtein disulfide-isomerase A4(Human)
Academia Sinica

US Patent
LigandChemical structure of BindingDB Monomer ID 801815BDBM801815((Z)-N-(3-(2-methoxy-5-(methoxycarbonyl)-4-propiola...)
Affinity DataIC50: 4.40nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/31/2026
Entry Details
US Patent

TargetProtein disulfide-isomerase A4(Human)
Academia Sinica

US Patent
LigandChemical structure of BindingDB Monomer ID 801799BDBM801799(methyl 4-methoxy-2-propiolamido-5-(3-(N-propioloyl...)
Affinity DataIC50: 4.70nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/31/2026
Entry Details
US Patent

TargetProtein disulfide-isomerase A4(Human)
Academia Sinica

US Patent
LigandChemical structure of BindingDB Monomer ID 801808BDBM801808(Methyl 5-(3-((tert-butoxycarbonyl)amino)propoxy)-4...)
Affinity DataIC50: 4.70nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/31/2026
Entry Details
US Patent

TargetProtein disulfide-isomerase A4(Human)
Academia Sinica

US Patent
LigandChemical structure of BindingDB Monomer ID 801797BDBM801797(methyl 5-(4-(1,3-dioxoisoindolin-2-yl)butoxy)-4-me...)
Affinity DataIC50: 5.60nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/31/2026
Entry Details
US Patent

TargetProtein disulfide-isomerase A4(Human)
Academia Sinica

US Patent
LigandChemical structure of BindingDB Monomer ID 801817BDBM801817((Z)-5-(3-((hydroxy(phenyl)methylene)amino)propoxy)...)
Affinity DataIC50: 6.20nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/31/2026
Entry Details
US Patent

TargetProtein disulfide-isomerase A4(Human)
Academia Sinica

US Patent
LigandChemical structure of BindingDB Monomer ID 801816BDBM801816((Z)-N-(3-(2-methoxy-4-propiolamido-5-((2-(trimethy...)
Affinity DataIC50: 7.5nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/31/2026
Entry Details
US Patent

TargetProtein disulfide-isomerase A4(Human)
Academia Sinica

US Patent
LigandChemical structure of BindingDB Monomer ID 50653743BDBM50653743(CHEMBL6082972 | US12605353, Compound 4)
Affinity DataIC50: 11.7nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/31/2026
Entry Details
US Patent

TargetProtein disulfide-isomerase A4(Human)
Academia Sinica

US Patent
LigandChemical structure of BindingDB Monomer ID 698936BDBM698936(2-amino-5-(benzyloxy)-4-methoxybenzoic propiolic a...)
Affinity DataIC50: 13.3nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2026
Entry Details
US Patent

TargetProtein disulfide-isomerase(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50561112BDBM50561112(CHEMBL4748449)
Affinity DataIC50: 23nMAssay Description:Inhibition of recombinant human wild-type N-terminal His-tagged PDIA1 expressed in Escherichia coli strain BL21(DE3) using bovine insulin as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetProtein disulfide-isomerase A4(Human)
Academia Sinica

US Patent
LigandChemical structure of BindingDB Monomer ID 698940BDBM698940(methyl 3,4,5-trimethoxy-2-propiolamidobenzoate | U...)
Affinity DataIC50: 42.5nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2026
Entry Details
US Patent

TargetProtein disulfide-isomerase A4(Human)
Academia Sinica

US Patent
LigandChemical structure of BindingDB Monomer ID 801795BDBM801795(methyl 5-(2-(1,3-dioxoisoindolin-2-yl)ethoxy)-4-me...)
Affinity DataIC50: 48.8nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/31/2026
Entry Details
US Patent

TargetProtein disulfide-isomerase A4(Human)
Academia Sinica

US Patent
LigandChemical structure of BindingDB Monomer ID 50652793BDBM50652793(CHEMBL5653589)
Affinity DataKd:  58nMAssay Description:Binding affinity to human PDIA4 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetProtein disulfide-isomerase(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50539388BDBM50539388(CHEMBL4637290)
Affinity DataKd:  62nMAssay Description:Reversible binding affinity to full length human N-terminal His6-tagged PDIA1 alpha domain (18 to 134 residues) expressed in Escherichia coli BL21 Go...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetProtein disulfide-isomerase A6(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50652793BDBM50652793(CHEMBL5653589)
Affinity DataKd:  63nMAssay Description:Binding affinity to human PDIA6 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetProtein disulfide-isomerase(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50561113BDBM50561113(CHEMBL4786482)
Affinity DataIC50: 72nMAssay Description:Inhibition of recombinant human wild-type N-terminal His-tagged PDIA1 expressed in Escherichia coli strain BL21(DE3) using bovine insulin as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetProtein disulfide-isomerase A4(Human)
Academia Sinica

US Patent
LigandChemical structure of BindingDB Monomer ID 801814BDBM801814(2-(trimethylsilyl)ethyl 4,5-dimethoxy-2-propiolami...)
Affinity DataIC50: 78.7nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/31/2026
Entry Details
US Patent

TargetProtein disulfide-isomerase A4(Human)
Academia Sinica

US Patent
LigandChemical structure of BindingDB Monomer ID 698939BDBM698939(benzyl 5-(benzyloxy)-4-methoxy-2-propiolamidobenzo...)
Affinity DataIC50: 84.9nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2026
Entry Details
US Patent

TargetProtein disulfide-isomerase(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 41977BDBM41977(6-[(4-chlorophenyl)-morpholin-4-ylmethyl]-1,3-benz...)
Affinity DataIC50: 92nMAssay Description:Inhibition of recombinant human wild-type N-terminal His-tagged PDIA1 expressed in Escherichia coli strain BL21(DE3) using bovine insulin as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetProtein disulfide-isomerase A3(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50652793BDBM50652793(CHEMBL5653589)
Affinity DataKd:  103nMAssay Description:Binding affinity to human PDIA3 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetProtein disulfide-isomerase(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50500107BDBM50500107(CHEMBL3741464)
Affinity DataIC50: 110nMAssay Description:Inhibition of recombinant human wild-type N-terminal His-tagged PDIA1 expressed in Escherichia coli strain BL21(DE3) using bovine insulin as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetProtein disulfide-isomerase(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50523105BDBM50523105(CHEMBL4483086)
Affinity DataIC50: 120nMAssay Description:Inhibition of recombinant human N-terminal His-tagged PDI expressed in Escherichia coli BL21 (DE3) pLysS assessed as reduction in enzyme-mediated bov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetProtein disulfide-isomerase(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50523107BDBM50523107(CHEMBL4472710)
Affinity DataIC50: 130nMAssay Description:Inhibition of recombinant human N-terminal His-tagged PDI expressed in Escherichia coli BL21 (DE3) pLysS assessed as reduction in enzyme-mediated bov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetProtein disulfide-isomerase(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 41988BDBM41988(6-[(4-methoxyphenyl)-morpholin-4-ylmethyl]-1,3-ben...)
Affinity DataIC50: 130nMAssay Description:Inhibition of recombinant human wild-type N-terminal His-tagged PDIA1 expressed in Escherichia coli strain BL21(DE3) using bovine insulin as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
Displayed 1 to 50 (of 412 total ) | Next | Last >>
Jump to: