Compile Data Set for Download or QSAR
Report error Found 663 Enz. Inhib. hit(s) with Target = 'RAC-gamma serine/threonine-protein kinase'
TargetRAC-gamma serine/threonine-protein kinase(Human)
Nanjing Chia Tai Tianqing Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 50606310BDBM50606310(CHEMBL5169427 | US20230286979, Isomer 2 of Example...)
Affinity DataIC50: 0.0900nMAssay Description:a) first, a compound stock solution (10 mM DMSO solution) was diluted with DMSO to obtain a 100 µM compound solution, the compound solution was dilut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetRAC-gamma serine/threonine-protein kinase(Human)
Nanjing Chia Tai Tianqing Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 50606310BDBM50606310(CHEMBL5169427 | US20230286979, Isomer 2 of Example...)
Affinity DataIC50: 0.0900nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2026
Entry Details
US Patent

TargetRAC-gamma serine/threonine-protein kinase(Human)
Nanjing Chia Tai Tianqing Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 50606310BDBM50606310(CHEMBL5169427 | US20230286979, Isomer 2 of Example...)
Affinity DataIC50: 0.0900nMAssay Description:After all the reagents were prepared according to the above method, except for the enzyme, the reagents were equilibrated to the room temperature and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent

TargetRAC-gamma serine/threonine-protein kinase(Human)
Nanjing Chia Tai Tianqing Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 50606310BDBM50606310(CHEMBL5169427 | US20230286979, Isomer 2 of Example...)
Affinity DataIC50: 0.0900nMAssay Description:Envision model plate reader (Molecular Devices)White 384-well plate (Thermo, Art. No. #264706)Main reagents included in an HTRF kinEASE TK kit (Cisbi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
US Patent

TargetRAC-gamma serine/threonine-protein kinase(Human)
Nanjing Chia Tai Tianqing Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 50606311BDBM50606311(CHEMBL5182446 | US20230321108, Isomer 2 of Example...)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of recombinant N-terminal GST tagged AKT2 (108 to 479 end residues) (unknown origin) catalytic domain expressed in Sf21 cells using peptid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetRAC-gamma serine/threonine-protein kinase(Human)
Nanjing Chia Tai Tianqing Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 50606310BDBM50606310(CHEMBL5169427 | US20230286979, Isomer 2 of Example...)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of recombinant N-terminal GST tagged AKT2 (108 to 479 end residues) (unknown origin) catalytic domain expressed in Sf21 cells using peptid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetRAC-gamma serine/threonine-protein kinase(Human)
Nanjing Chia Tai Tianqing Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 50528415BDBM50528415(CHEMBL4457064)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of Akt3 (unknown origin) by mobile shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetRAC-gamma serine/threonine-protein kinase(Human)
Nanjing Chia Tai Tianqing Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 50606346BDBM50606346(CHEMBL5197007 | US20230321108, Isomer 4 of Example...)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of recombinant N-terminal GST tagged AKT2 (108 to 479 end residues) (unknown origin) catalytic domain expressed in Sf21 cells using peptid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetRAC-gamma serine/threonine-protein kinase(Human)
Nanjing Chia Tai Tianqing Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 50606311BDBM50606311(CHEMBL5182446 | US20230321108, Isomer 2 of Example...)
Affinity DataIC50: 0.120nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2026
Entry Details
US Patent

TargetRAC-gamma serine/threonine-protein kinase(Human)
Nanjing Chia Tai Tianqing Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 50606346BDBM50606346(CHEMBL5197007 | US20230321108, Isomer 4 of Example...)
Affinity DataIC50: 0.120nMAssay Description:a) first, a compound stock solution (10 mM DMSO solution) was diluted with DMSO to obtain a 100 µM compound solution, the compound solution was dilut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetRAC-gamma serine/threonine-protein kinase(Human)
Nanjing Chia Tai Tianqing Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 50606346BDBM50606346(CHEMBL5197007 | US20230321108, Isomer 4 of Example...)
Affinity DataIC50: 0.120nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2026
Entry Details
US Patent

TargetRAC-gamma serine/threonine-protein kinase(Human)
Nanjing Chia Tai Tianqing Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 50528409BDBM50528409(CHEMBL4441825)
Affinity DataIC50: 0.120nMAssay Description:Inhibition of Akt3 (unknown origin) by mobile shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetRAC-gamma serine/threonine-protein kinase(Human)
Nanjing Chia Tai Tianqing Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 50606311BDBM50606311(CHEMBL5182446 | US20230321108, Isomer 2 of Example...)
Affinity DataIC50: 0.120nMAssay Description:a) first, a compound stock solution (10 mM DMSO solution) was diluted with DMSO to obtain a 100 µM compound solution, the compound solution was dilut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetRAC-gamma serine/threonine-protein kinase(Human)
Nanjing Chia Tai Tianqing Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 803760BDBM803760(US12617784, Example 28)
Affinity DataIC50: 0.190nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/14/2026
Entry Details
US Patent

TargetRAC-gamma serine/threonine-protein kinase(Human)
Nanjing Chia Tai Tianqing Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 50606329BDBM50606329(CHEMBL5175332 | US12617784, Example 23-1)
Affinity DataIC50: 0.190nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2026
Entry Details
US Patent

TargetRAC-gamma serine/threonine-protein kinase(Human)
Nanjing Chia Tai Tianqing Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 803756BDBM803756(US12617784, Example 25-2)
Affinity DataIC50: 0.190nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/14/2026
Entry Details
US Patent

TargetRAC-gamma serine/threonine-protein kinase(Human)
Nanjing Chia Tai Tianqing Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 50606347BDBM50606347(CHEMBL5190230 | US12617784, Example 21)
Affinity DataIC50: 0.200nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2026
Entry Details
US Patent

TargetRAC-gamma serine/threonine-protein kinase(Human)
Nanjing Chia Tai Tianqing Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 50606341BDBM50606341(CHEMBL5195745 | US12617784, Example 10)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of recombinant N-terminal GST tagged AKT2 (108 to 479 end residues) (unknown origin) catalytic domain expressed in Sf21 cells using peptid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetRAC-gamma serine/threonine-protein kinase(Human)
Nanjing Chia Tai Tianqing Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 50606309BDBM50606309(CHEMBL5206905 | US12617784, Example 2R)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of recombinant N-terminal GST tagged AKT2 (108 to 479 end residues) (unknown origin) catalytic domain expressed in Sf21 cells using peptid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetRAC-gamma serine/threonine-protein kinase(Human)
Nanjing Chia Tai Tianqing Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 50606329BDBM50606329(CHEMBL5175332 | US12617784, Example 23-1)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of recombinant N-terminal GST tagged AKT2 (108 to 479 end residues) (unknown origin) catalytic domain expressed in Sf21 cells using peptid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetRAC-gamma serine/threonine-protein kinase(Human)
Nanjing Chia Tai Tianqing Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 803766BDBM803766(US12617784, Example 33-1)
Affinity DataIC50: 0.200nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/14/2026
Entry Details
US Patent

TargetRAC-gamma serine/threonine-protein kinase(Human)
Nanjing Chia Tai Tianqing Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 50606345BDBM50606345(CHEMBL5180219)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of recombinant N-terminal GST tagged AKT2 (108 to 479 end residues) (unknown origin) catalytic domain expressed in Sf21 cells using peptid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetRAC-gamma serine/threonine-protein kinase(Human)
Nanjing Chia Tai Tianqing Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 50606347BDBM50606347(CHEMBL5190230 | US12617784, Example 21)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of recombinant N-terminal GST tagged AKT2 (108 to 479 end residues) (unknown origin) catalytic domain expressed in Sf21 cells using peptid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetRAC-gamma serine/threonine-protein kinase(Human)
Nanjing Chia Tai Tianqing Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 50606341BDBM50606341(CHEMBL5195745 | US12617784, Example 10)
Affinity DataIC50: 0.210nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2026
Entry Details
US Patent

TargetRAC-gamma serine/threonine-protein kinase(Human)
Nanjing Chia Tai Tianqing Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 50606342BDBM50606342(CHEMBL5177491 | US12617784, Example 11)
Affinity DataIC50: 0.25nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2026
Entry Details
US Patent

TargetRAC-gamma serine/threonine-protein kinase(Human)
Nanjing Chia Tai Tianqing Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 803776BDBM803776(US12617784, Example 38)
Affinity DataIC50: 0.280nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/14/2026
Entry Details
US Patent

TargetRAC-gamma serine/threonine-protein kinase(Human)
Nanjing Chia Tai Tianqing Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 50606309BDBM50606309(CHEMBL5206905 | US12617784, Example 2R)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of recombinant N-terminal GST tagged AKT2 (108 to 479 end residues) (unknown origin) catalytic domain expressed in Sf21 cells using peptid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetRAC-gamma serine/threonine-protein kinase(Human)
Nanjing Chia Tai Tianqing Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 50606342BDBM50606342(CHEMBL5177491 | US12617784, Example 11)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of recombinant N-terminal GST tagged AKT2 (108 to 479 end residues) (unknown origin) catalytic domain expressed in Sf21 cells using peptid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetRAC-gamma serine/threonine-protein kinase(Human)
Nanjing Chia Tai Tianqing Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 50606344BDBM50606344(CHEMBL5189707)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of recombinant N-terminal GST tagged AKT2 (108 to 479 end residues) (unknown origin) catalytic domain expressed in Sf21 cells using peptid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetRAC-gamma serine/threonine-protein kinase(Human)
Nanjing Chia Tai Tianqing Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 50606309BDBM50606309(CHEMBL5206905 | US12617784, Example 2R)
Affinity DataIC50: 0.400nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2026
Entry Details
US Patent

TargetRAC-gamma serine/threonine-protein kinase(Human)
Nanjing Chia Tai Tianqing Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 50606319BDBM50606319(CHEMBL5195664 | US12617784, Example 20)
Affinity DataIC50: 0.400nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2026
Entry Details
US Patent

TargetRAC-gamma serine/threonine-protein kinase(Human)
Nanjing Chia Tai Tianqing Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 50606319BDBM50606319(CHEMBL5195664 | US12617784, Example 20)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of recombinant N-terminal GST tagged AKT2 (108 to 479 end residues) (unknown origin) catalytic domain expressed in Sf21 cells using peptid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetRAC-gamma serine/threonine-protein kinase(Human)
Nanjing Chia Tai Tianqing Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 803764BDBM803764(US12617784, Example 32-1)
Affinity DataIC50: 0.410nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/14/2026
Entry Details
US Patent

TargetRAC-gamma serine/threonine-protein kinase(Human)
Nanjing Chia Tai Tianqing Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 50606349BDBM50606349(CHEMBL5171561 | US12617784, Example 27-1)
Affinity DataIC50: 0.480nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2026
Entry Details
US Patent

TargetRAC-gamma serine/threonine-protein kinase(Human)
Nanjing Chia Tai Tianqing Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 50606313BDBM50606313(CHEMBL5193325)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of recombinant N-terminal GST tagged AKT2 (108 to 479 end residues) (unknown origin) catalytic domain expressed in Sf21 cells using peptid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetRAC-gamma serine/threonine-protein kinase(Human)
Nanjing Chia Tai Tianqing Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 50606349BDBM50606349(CHEMBL5171561 | US12617784, Example 27-1)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of recombinant N-terminal GST tagged AKT2 (108 to 479 end residues) (unknown origin) catalytic domain expressed in Sf21 cells using peptid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetRAC-gamma serine/threonine-protein kinase(Human)
Nanjing Chia Tai Tianqing Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 50606348BDBM50606348(CHEMBL5187172)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of recombinant N-terminal GST tagged AKT2 (108 to 479 end residues) (unknown origin) catalytic domain expressed in Sf21 cells using peptid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetRAC-gamma serine/threonine-protein kinase(Human)
Nanjing Chia Tai Tianqing Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 803757BDBM803757(US12617784, Example 26)
Affinity DataIC50: 0.520nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/14/2026
Entry Details
US Patent

TargetRAC-gamma serine/threonine-protein kinase(Human)
Nanjing Chia Tai Tianqing Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 803749BDBM803749(4-((S)-4-((S)-2-(4-chlorophenyl)-3-(isopropylamino...)
Affinity DataIC50: 0.560nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/14/2026
Entry Details
US Patent

TargetRAC-gamma serine/threonine-protein kinase(Human)
Nanjing Chia Tai Tianqing Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 2579BDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 0.640nMAssay Description:Inhibition of AKT3More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRAC-gamma serine/threonine-protein kinase(Human)
Nanjing Chia Tai Tianqing Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 50606314BDBM50606314(CHEMBL5187508)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of recombinant N-terminal GST tagged AKT2 (108 to 479 end residues) (unknown origin) catalytic domain expressed in Sf21 cells using peptid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetRAC-gamma serine/threonine-protein kinase(Human)
Nanjing Chia Tai Tianqing Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 50306165BDBM50306165(3-((2S)-2-amino-3-(2-amino-5-(3-methyl-1H-pyrazolo...)
Affinity DataIC50: 1nMAssay Description:Inhibition of human AKT3More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetRAC-gamma serine/threonine-protein kinase(Human)
Nanjing Chia Tai Tianqing Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 50606323BDBM50606323(CHEMBL5189610 | US12617784, Example 16-2)
Affinity DataIC50: 1nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2026
Entry Details
US Patent

TargetRAC-gamma serine/threonine-protein kinase(Human)
Nanjing Chia Tai Tianqing Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 50306155BDBM50306155(3-((S)-2-amino-3-(1H-indol-3-yl)propoxy)-5-(3-meth...)
Affinity DataIC50: 1nMAssay Description:Inhibition of human AKT3More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetRAC-gamma serine/threonine-protein kinase(Human)
Nanjing Chia Tai Tianqing Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 50606323BDBM50606323(CHEMBL5189610 | US12617784, Example 16-2)
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant N-terminal GST tagged AKT2 (108 to 479 end residues) (unknown origin) catalytic domain expressed in Sf21 cells using peptid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetRAC-gamma serine/threonine-protein kinase(Human)
Nanjing Chia Tai Tianqing Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 50305878BDBM50305878((S)-1-(6-(furan-3-yl)-5-(3-methyl-1H-indazol-5-yl)...)
Affinity DataIC50: 1nMAssay Description:Inhibition of AKT3More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetRAC-gamma serine/threonine-protein kinase(Human)
Nanjing Chia Tai Tianqing Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 50305883BDBM50305883((S)-1-(6-(furan-3-yl)-5-(3-methyl-1H-pyrazolo[3,4-...)
Affinity DataIC50: 1nMAssay Description:Inhibition of AKT3More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetRAC-gamma serine/threonine-protein kinase(Human)
Nanjing Chia Tai Tianqing Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 130909BDBM130909(US8822500, Stauro- sporine | US9920060, Staurospor...)
Affinity DataIC50: 1nMAssay Description:Inhibition of AKT3 (unknown origin) in the presence of [33P]ATP by kinase hotspot assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRAC-gamma serine/threonine-protein kinase(Human)
Nanjing Chia Tai Tianqing Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 50316192BDBM50316192(4-(2-(4-amino-1,2,5-oxadiazol-3-yl)-6-((R)-2-amino...)
Affinity DataIC50: 1nMAssay Description:Inhibition of AKT3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetRAC-gamma serine/threonine-protein kinase(Human)
Nanjing Chia Tai Tianqing Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 50306164BDBM50306164(3-((2S)-2-amino-3-(2-amino-5-(3-methyl-1H-pyrazolo...)
Affinity DataIC50: 1nMAssay Description:Inhibition of human AKT3More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
Displayed 1 to 50 (of 663 total ) | Next | Last >>
Jump to: