Compile Data Set for Download or QSAR
Report error Found 633 Enz. Inhib. hit(s) with Target = 'Ras-related C3 botulinum toxin substrate 1'
LigandChemical structure of BindingDB Monomer ID 54623BDBM54623(2-(2,5-dichlorophenyl)-5-(4-fluorophenyl)-3-(4-met...)
Affinity DataKi:  10nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2011
Entry Details
PCBioAssay
LigandChemical structure of BindingDB Monomer ID 54661BDBM54661(4-[3-(4-methoxyphenyl)-5-methyl-3,4-dihydropyrazol...)
Affinity DataKi:  10nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2011
Entry Details
PCBioAssay
LigandChemical structure of BindingDB Monomer ID 54619BDBM54619(UNM-0000305858 | 5-(4-chlorophenyl)-3-(3,4-dimetho...)
Affinity DataKi:  10nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2011
Entry Details
PCBioAssay
LigandChemical structure of BindingDB Monomer ID 41685BDBM41685(4-[5-(4-bromophenyl)-3-(4-fluorophenyl)-3,4-dihydr...)
Affinity DataEC50:  14nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2011
Entry Details
PCBioAssay
LigandChemical structure of BindingDB Monomer ID 54709BDBM54709(1-[4-(4-bromophenyl)piperazin-1-yl]-3-[3-(4-methox...)
Affinity DataKi:  20nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2011
Entry Details
PCBioAssay
LigandChemical structure of BindingDB Monomer ID 42384BDBM42384(SMR000072200 | 2-(2-phenylethylthio)-3-pyridinecar...)
Affinity DataEC50:  20.2nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2011
Entry Details
PCBioAssay
LigandChemical structure of BindingDB Monomer ID 42384BDBM42384(SMR000072200 | 2-(2-phenylethylthio)-3-pyridinecar...)
Affinity DataEC50:  25.4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2011
Entry Details
PCBioAssay
LigandChemical structure of BindingDB Monomer ID 54622BDBM54622(cid_2883119 | UNM-0000305861 | 3-(3,4-dimethoxyphe...)
Affinity DataEC50:  27nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2011
Entry Details
PCBioAssay
LigandChemical structure of BindingDB Monomer ID 54653BDBM54653(UNM-0000306148 | KUC103429N | cid_44143704 | 4-[3-...)
Affinity DataEC50:  30nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2011
Entry Details
PCBioAssay
LigandChemical structure of BindingDB Monomer ID 41685BDBM41685(4-[5-(4-bromophenyl)-3-(4-fluorophenyl)-3,4-dihydr...)
Affinity DataEC50:  32nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2011
Entry Details
PCBioAssay
LigandChemical structure of BindingDB Monomer ID 54638BDBM54638(UNM-0000306112 | KUC103394N | 4-[5-(2-bromophenyl)...)
Affinity DataKi:  40nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2011
Entry Details
PCBioAssay
TargetRas-related C3 botulinum toxin substrate 1(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50618632BDBM50618632(CHEMBL1186585)
Affinity DataKd:  40nMAssay Description:Binding affinity to Rac1 (unknown origin) expressed in Escherichia coli BL21 (DE3) cells assessed as dissociation constant by fluorescence anisotropy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetRas-related C3 botulinum toxin substrate 1(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50618632BDBM50618632(CHEMBL1186585)
Affinity DataKd:  50nMAssay Description:Binding affinity to Rac1b (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 54570BDBM54570(3-[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]-1-[4-...)
Affinity DataKi:  50nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2011
Entry Details
PCBioAssay
LigandChemical structure of BindingDB Monomer ID 54570BDBM54570(3-[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]-1-[4-...)
Affinity DataKi:  60nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2011
Entry Details
PCBioAssay
LigandChemical structure of BindingDB Monomer ID 54594BDBM54594(UNM-0000305832 | cid_2830691 | 5-(4-bromophenyl)-2...)
Affinity DataKi:  60nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2011
Entry Details
PCBioAssay
LigandChemical structure of BindingDB Monomer ID 54661BDBM54661(4-[3-(4-methoxyphenyl)-5-methyl-3,4-dihydropyrazol...)
Affinity DataEC50:  63nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2011
Entry Details
PCBioAssay
LigandChemical structure of BindingDB Monomer ID 54571BDBM54571(KUC103398N | 1-[4-(4-fluorophenyl)-1-piperazinyl]-...)
Affinity DataKi:  80nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2011
Entry Details
PCBioAssay
TargetRas-related C3 botulinum toxin substrate 1(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 787065BDBM787065(US20250346604, Compound (100))
Affinity DataIC50: 80nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/5/2026
Entry Details US Patent

LigandChemical structure of BindingDB Monomer ID 43221BDBM43221(cid_1067700 | SMR000297947 | 5,5-dimethyl-2-(pheny...)
Affinity DataEC50:  80.6nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2011
Entry Details
PCBioAssay
LigandChemical structure of BindingDB Monomer ID 43221BDBM43221(cid_1067700 | SMR000297947 | 5,5-dimethyl-2-(pheny...)
Affinity DataEC50:  80.6nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2011
Entry Details
PCBioAssay
LigandChemical structure of BindingDB Monomer ID 46331BDBM46331(cid_2208880 | SMR000294277 | 2-(5-bromo-2-furoyl)-...)
Affinity DataEC50:  85.7nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2011
Entry Details
PCBioAssay
LigandChemical structure of BindingDB Monomer ID 54623BDBM54623(2-(2,5-dichlorophenyl)-5-(4-fluorophenyl)-3-(4-met...)
Affinity DataEC50:  89nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2011
Entry Details
PCBioAssay
LigandChemical structure of BindingDB Monomer ID 46328BDBM46328(MLS000393082 | N-[3-(1H-benzimidazol-2-yl)-4,5,6,7...)
Affinity DataEC50:  99.9nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2011
Entry Details
PCBioAssay
LigandChemical structure of BindingDB Monomer ID 54578BDBM54578(1-[4-(2-fluorophenyl)piperazin-1-yl]-3-[3-(4-metho...)
Affinity DataKi:  100nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2011
Entry Details
PCBioAssay
TargetRas-related C3 botulinum toxin substrate 1(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50391237BDBM50391237(CHEMBL5290216)
Affinity DataIC50: 100nMAssay Description:Inhibition of Rac1 GTPase in human breast cancer cell line treated for 24 hrs by western blot assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 43246BDBM43246(SMR000070396 | 2-[(2,5-dimethyl-3-furanyl)-oxometh...)
Affinity DataEC50:  103nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2011
Entry Details
PCBioAssay
LigandChemical structure of BindingDB Monomer ID 54554BDBM54554(3-[3-(2-chlorophenyl)-1,2,4-oxadiazol-5-yl]-1-[4-(...)
Affinity DataKi:  110nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2011
Entry Details
PCBioAssay
LigandChemical structure of BindingDB Monomer ID 54584BDBM54584(KUC103432N | 1-[4-(2,5-dimethylphenyl)-1-piperidin...)
Affinity DataKi:  110nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2011
Entry Details
PCBioAssay
LigandChemical structure of BindingDB Monomer ID 54565BDBM54565(1-[4-(2,5-dimethylphenyl)piperazin-1-yl]-3-[3-(3-m...)
Affinity DataKi:  110nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2011
Entry Details
PCBioAssay
LigandChemical structure of BindingDB Monomer ID 54554BDBM54554(3-[3-(2-chlorophenyl)-1,2,4-oxadiazol-5-yl]-1-[4-(...)
Affinity DataKi:  120nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2011
Entry Details
PCBioAssay
LigandChemical structure of BindingDB Monomer ID 54553BDBM54553(KUC103364N | UNM-0000306074 | cid_42596902 | 1-[4-...)
Affinity DataKi:  120nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2011
Entry Details
PCBioAssay
LigandChemical structure of BindingDB Monomer ID 54576BDBM54576(1-[4-(2,3-dimethylphenyl)-1-piperazinyl]-3-[3-(4-m...)
Affinity DataKi:  120nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2011
Entry Details
PCBioAssay
LigandChemical structure of BindingDB Monomer ID 54553BDBM54553(KUC103364N | UNM-0000306074 | cid_42596902 | 1-[4-...)
Affinity DataKi:  120nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2011
Entry Details
PCBioAssay
LigandChemical structure of BindingDB Monomer ID 54569BDBM54569(cid_42608817 | KUC103383N | UNM-0000306090 | 3-[3-...)
Affinity DataKi:  130nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2011
Entry Details
PCBioAssay
LigandChemical structure of BindingDB Monomer ID 54569BDBM54569(cid_42608817 | KUC103383N | UNM-0000306090 | 3-[3-...)
Affinity DataKi:  130nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2011
Entry Details
PCBioAssay
LigandChemical structure of BindingDB Monomer ID 54619BDBM54619(UNM-0000305858 | 5-(4-chlorophenyl)-3-(3,4-dimetho...)
Affinity DataEC50:  139nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2011
Entry Details
PCBioAssay
LigandChemical structure of BindingDB Monomer ID 54555BDBM54555(KUC103366N | 1-[4-(2,5-dimethylphenyl)-1-piperazin...)
Affinity DataKi:  140nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2011
Entry Details
PCBioAssay
LigandChemical structure of BindingDB Monomer ID 54576BDBM54576(1-[4-(2,3-dimethylphenyl)-1-piperazinyl]-3-[3-(4-m...)
Affinity DataKi:  140nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2011
Entry Details
PCBioAssay
LigandChemical structure of BindingDB Monomer ID 54548BDBM54548(3-[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]-1-[4-...)
Affinity DataKi:  140nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2011
Entry Details
PCBioAssay
LigandChemical structure of BindingDB Monomer ID 54571BDBM54571(KUC103398N | 1-[4-(4-fluorophenyl)-1-piperazinyl]-...)
Affinity DataKi:  150nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2011
Entry Details
PCBioAssay
LigandChemical structure of BindingDB Monomer ID 54549BDBM54549(UNM-0000306070 | KUC103356N | 1-[4-(2,5-dimethylph...)
Affinity DataKi:  150nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2011
Entry Details
PCBioAssay
TargetRas-related C3 botulinum toxin substrate 1(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 787067BDBM787067(US20250346604, Compound (105))
Affinity DataIC50: 150nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/5/2026
Entry Details US Patent

LigandChemical structure of BindingDB Monomer ID 43252BDBM43252(ML097 | 2-[(2-bromophenyl)methoxy]benzoic acid | c...)
Affinity DataEC50:  151nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2011
Entry Details
PCBioAssay
LigandChemical structure of BindingDB Monomer ID 54557BDBM54557(cid_42596906 | KUC103368N | UNM-0000306078 | 1-[4-...)
Affinity DataKi:  160nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2011
Entry Details
PCBioAssay
LigandChemical structure of BindingDB Monomer ID 54556BDBM54556(KUC103367N | 3-[3-(3-bromophenyl)-1,2,4-oxadiazol-...)
Affinity DataKi:  160nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2011
Entry Details
PCBioAssay
LigandChemical structure of BindingDB Monomer ID 54559BDBM54559(KUC103370N | cid_42596907 | 1-[4-(2-bromophenyl)pi...)
Affinity DataKi:  160nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2011
Entry Details
PCBioAssay
LigandChemical structure of BindingDB Monomer ID 54575BDBM54575(3-[3-(2-bromophenyl)-1,2,4-oxadiazol-5-yl]-1-[4-(2...)
Affinity DataKi:  160nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2011
Entry Details
PCBioAssay
LigandChemical structure of BindingDB Monomer ID 54561BDBM54561(UNM-0000306082 | KUC103372N | cid_42596909 | 3-[3-...)
Affinity DataKi:  160nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2011
Entry Details
PCBioAssay
LigandChemical structure of BindingDB Monomer ID 54544BDBM54544(3-[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]-1-(4-...)
Affinity DataKi:  160nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2011
Entry Details
PCBioAssay
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