Compile Data Set for Download or QSAR
Report error Found 358 Enz. Inhib. hit(s) with Target = 'Ribosomal protein S6 kinase beta-1 [T412E]'
TargetRibosomal protein S6 kinase beta-1 [T412E](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 224498BDBM224498(US9321760, 176 | US10080750, Compound 176 | US9662...)
Affinity DataIC50: 0.800nMpH: 7.5Assay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

TargetRibosomal protein S6 kinase beta-1 [T412E](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 224487BDBM224487(US9321760, 165 | US10080750, Compound 165 | US9662...)
Affinity DataIC50: 0.900nMpH: 7.5Assay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

TargetRibosomal protein S6 kinase beta-1 [T412E](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 364971BDBM364971(US9867826, Compound 2 | 4-Amino-6-{3,4-cis-4-[1-(2...)
Affinity DataIC50: 1nMAssay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2019
Entry Details
US Patent

TargetRibosomal protein S6 kinase beta-1 [T412E](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 364981BDBM364981(US9867826, Compound 10 | 6-{3,4-cis-4-[1-(2-Azetid...)
Affinity DataIC50: 1nMAssay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2019
Entry Details
US Patent

TargetRibosomal protein S6 kinase beta-1 [T412E](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 364970BDBM364970(US9867826, Compound 1 | 4-Amino-6-{3,4-cis-4-[1-(2...)
Affinity DataIC50: 1nMAssay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2019
Entry Details
US Patent

TargetRibosomal protein S6 kinase beta-1 [T412E](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 224485BDBM224485(US9321760, 163 | US10080750, Compound 163 | US9662...)
Affinity DataIC50: 1.30nMpH: 7.5Assay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

TargetRibosomal protein S6 kinase beta-1 [T412E](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 224508BDBM224508(US9321760, 186 | US10080750, Compound 186 | US9662...)
Affinity DataIC50: 1.40nMpH: 7.5Assay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

TargetRibosomal protein S6 kinase beta-1 [T412E](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 224340BDBM224340(US9321760, 17 | US10080750, Compound 17 | US966233...)
Affinity DataIC50: 1.70nMpH: 7.5Assay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

TargetRibosomal protein S6 kinase beta-1 [T412E](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 224469BDBM224469(US9321760, 147 | US10080750, Compound 147 | US9662...)
Affinity DataIC50: 2nMpH: 7.5Assay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

TargetRibosomal protein S6 kinase beta-1 [T412E](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 224325BDBM224325(US9321760, 2 | US10080750, Compound 2 | US9662330,...)
Affinity DataIC50: 2.20nMpH: 7.5Assay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

TargetRibosomal protein S6 kinase beta-1 [T412E](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 224460BDBM224460(US9321760, 138 | US10080750, Compound 138 | US9662...)
Affinity DataIC50: 2.5nMpH: 7.5Assay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

TargetRibosomal protein S6 kinase beta-1 [T412E](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 224497BDBM224497(US9321760, 175 | US10080750, Compound 175 | US9662...)
Affinity DataIC50: 2.60nMpH: 7.5Assay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

TargetRibosomal protein S6 kinase beta-1 [T412E](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 224326BDBM224326(US9321760, 3 | US10080750, Compound 3 | US9662330,...)
Affinity DataIC50: 2.60nMpH: 7.5Assay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

TargetRibosomal protein S6 kinase beta-1 [T412E](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 224526BDBM224526(US9321760, 204 | US10080750, Compound 204 | US9662...)
Affinity DataIC50: 2.60nMpH: 7.5Assay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

TargetRibosomal protein S6 kinase beta-1 [T412E](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 224330BDBM224330(US9321760, 7 | US10080750, Compound 7 | US9662330,...)
Affinity DataIC50: 2.80nMpH: 7.5Assay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

TargetRibosomal protein S6 kinase beta-1 [T412E](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 224376BDBM224376(US9321760, 53 | US10080750, Compound 53 | US966233...)
Affinity DataIC50: 3.20nMpH: 7.5Assay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

TargetRibosomal protein S6 kinase beta-1 [T412E](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 224517BDBM224517(US9321760, 195 | US10080750, Compound 195 | US9662...)
Affinity DataIC50: 3.30nMpH: 7.5Assay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

TargetRibosomal protein S6 kinase beta-1 [T412E](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 224375BDBM224375(US9321760, 52 | US10080750, Compound 52 | US966233...)
Affinity DataIC50: 3.30nMpH: 7.5Assay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

TargetRibosomal protein S6 kinase beta-1 [T412E](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 224505BDBM224505(US9321760, 183 | US10080750, Compound 183 | US9662...)
Affinity DataIC50: 3.40nMpH: 7.5Assay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

TargetRibosomal protein S6 kinase beta-1 [T412E](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 224331BDBM224331(US9321760, 8 | US10080750, Compound 8 | US9662330,...)
Affinity DataIC50: 3.40nMpH: 7.5Assay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

TargetRibosomal protein S6 kinase beta-1 [T412E](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 224348BDBM224348(US9321760, 25 | US10080750, Compound 25 | US966233...)
Affinity DataIC50: 3.40nMpH: 7.5Assay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

TargetRibosomal protein S6 kinase beta-1 [T412E](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 224483BDBM224483(US9321760, 161 | US10080750, Compound 161 | US9662...)
Affinity DataIC50: 4nMpH: 7.5Assay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

TargetRibosomal protein S6 kinase beta-1 [T412E](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 224491BDBM224491(US9321760, 169 | US10080750, Compound 169 | US9662...)
Affinity DataIC50: 4.10nMpH: 7.5Assay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

TargetRibosomal protein S6 kinase beta-1 [T412E](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 224350BDBM224350(US9321760, 27 | US10080750, Compound 27 | US966233...)
Affinity DataIC50: 4.20nMpH: 7.5Assay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

TargetRibosomal protein S6 kinase beta-1 [T412E](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 224481BDBM224481(US9321760, 159 | US10080750, Compound 159 | US9662...)
Affinity DataIC50: 4.40nMpH: 7.5Assay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

TargetRibosomal protein S6 kinase beta-1 [T412E](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 224327BDBM224327(US9321760, 4 | US10080750, Compound 4 | US9662330,...)
Affinity DataIC50: 4.5nMpH: 7.5Assay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

TargetRibosomal protein S6 kinase beta-1 [T412E](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 224377BDBM224377(US9321760, 54 | US10080750, Compound 54 | US966233...)
Affinity DataIC50: 4.5nMpH: 7.5Assay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

TargetRibosomal protein S6 kinase beta-1 [T412E](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 224462BDBM224462(US9321760, 140 | US10080750, Compound 140 | US9662...)
Affinity DataIC50: 4.60nMpH: 7.5Assay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

TargetRibosomal protein S6 kinase beta-1 [T412E](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 224380BDBM224380(US9321760, 57 | US10080750, Compound 57 | US966233...)
Affinity DataIC50: 4.70nMpH: 7.5Assay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

TargetRibosomal protein S6 kinase beta-1 [T412E](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 224520BDBM224520(US9321760, 198 | US10080750, Compound 198 | US9662...)
Affinity DataIC50: 4.80nMpH: 7.5Assay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

TargetRibosomal protein S6 kinase beta-1 [T412E](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 224338BDBM224338(US9321760, 15 | US10080750, Compound 15 | US966233...)
Affinity DataIC50: 4.90nMpH: 7.5Assay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

TargetRibosomal protein S6 kinase beta-1 [T412E](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 224339BDBM224339(US9321760, 16 | US10080750, Compound 16 | US966233...)
Affinity DataIC50: 4.90nMpH: 7.5Assay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

TargetRibosomal protein S6 kinase beta-1 [T412E](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 224378BDBM224378(US9321760, 55 | US10080750, Compound 55 | US966233...)
Affinity DataIC50: 5.20nMpH: 7.5Assay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

TargetRibosomal protein S6 kinase beta-1 [T412E](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 224347BDBM224347(US9321760, 24 | US10080750, Compound 24 | US966233...)
Affinity DataIC50: 5.30nMpH: 7.5Assay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

TargetRibosomal protein S6 kinase beta-1 [T412E](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 224525BDBM224525(US9321760, 203 | US10080750, Compound 203 | US9662...)
Affinity DataIC50: 5.30nMpH: 7.5Assay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

TargetRibosomal protein S6 kinase beta-1 [T412E](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 365731BDBM365731(5-Chloro-6-{(3S,4R)-4-[1-(2-dimethylamino-ethyl)-4...)
Affinity DataIC50: 5.5nMAssay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2019
Entry Details
US Patent

TargetRibosomal protein S6 kinase beta-1 [T412E](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 365019BDBM365019(US9867826, Compound 29 | 5-Chloro-6-{(3R,4S)-4-[1-...)
Affinity DataIC50: 5.5nMAssay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2019
Entry Details
US Patent

TargetRibosomal protein S6 kinase beta-1 [T412E](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 364993BDBM364993(6-{cis-4-[1-(2-Dimethylamino-ethyl)-4-(4-fluoro-3-...)
Affinity DataIC50: 5.5nMAssay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2019
Entry Details
US Patent

TargetRibosomal protein S6 kinase beta-1 [T412E](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 365732BDBM365732(6-{(3S,4R)-4-[1-(2-Dimethylamino-ethyl)-4-(4-fluor...)
Affinity DataIC50: 5.5nMAssay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2019
Entry Details
US Patent

TargetRibosomal protein S6 kinase beta-1 [T412E](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 365016BDBM365016(US9867826, Compound 26 | 6-{cis-3-Fluoro-4-[4-(4-f...)
Affinity DataIC50: 5.5nMAssay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2019
Entry Details
US Patent

TargetRibosomal protein S6 kinase beta-1 [T412E](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 365014BDBM365014(US9867826, Compound 25 | 5-Chloro-6-cis-4-[1-(2-di...)
Affinity DataIC50: 5.5nMAssay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2019
Entry Details
US Patent

TargetRibosomal protein S6 kinase beta-1 [T412E](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 365003BDBM365003(4-Amino-6-{cis-4-[1-(2-azetidin-1-yl-ethyl)-4-(4-f...)
Affinity DataIC50: 5.5nMAssay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2019
Entry Details
US Patent

TargetRibosomal protein S6 kinase beta-1 [T412E](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 365739BDBM365739(6-{cis-3-Fluoro-4-[4-(4-fluoro-3-methyl-phenyl)-1-...)
Affinity DataIC50: 5.5nMAssay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2019
Entry Details
US Patent

TargetRibosomal protein S6 kinase beta-1 [T412E](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 364974BDBM364974(US9867826, Compound 5 | 4-Amino-6-{3,4-cis-4-[1-(2...)
Affinity DataIC50: 5.5nMAssay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2019
Entry Details
US Patent

TargetRibosomal protein S6 kinase beta-1 [T412E](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 365738BDBM365738(6-{cis-3-Fluoro-4-[4-(4-fluoro-3-methyl-phenyl)-1-...)
Affinity DataIC50: 5.5nMAssay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2019
Entry Details
US Patent

TargetRibosomal protein S6 kinase beta-1 [T412E](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 364978BDBM364978(US9867826, Compound 8 | 4-Amino-6-{3,4-trans-4-[1-...)
Affinity DataIC50: 5.5nMAssay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2019
Entry Details
US Patent

TargetRibosomal protein S6 kinase beta-1 [T412E](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 365741BDBM365741(4-Amino-6-{(3R,4S)-4-[1-(2-azetidin-1-yl-ethyl)-4-...)
Affinity DataIC50: 5.5nMAssay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2019
Entry Details
US Patent

TargetRibosomal protein S6 kinase beta-1 [T412E](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 364976BDBM364976(US9867826, Compound 7 | 4-amino-6-{3,4-trans-4-[1-...)
Affinity DataIC50: 5.5nMAssay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2019
Entry Details
US Patent

TargetRibosomal protein S6 kinase beta-1 [T412E](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 365740BDBM365740(6-{cis-4-[1-(2-Azetidin-1-yl-ethyl)-4-(4-fluoro-3-...)
Affinity DataIC50: 5.5nMAssay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2019
Entry Details
US Patent

TargetRibosomal protein S6 kinase beta-1 [T412E](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 365735BDBM365735(6-{(3S,4R)-4-[1-(2-Azetidin-1-yl-ethyl)-4-(4-fluor...)
Affinity DataIC50: 5.5nMAssay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2019
Entry Details
US Patent

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