Report error Found 6839 Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase B-raf [V600E]'
Affinity DataIC50: 0.0200nMAssay Description:C-Raf TR refers to a truncated C-Raf protein, a Δ1-324 deletion mutant.C-Raf FL refers to the full-length C-Raf protein.Full length MEK1 with an...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0200nMpH: 7.5 T: 2°CAssay Description:Raf and biotinylated Mek, kinase dead, were combined at 2x final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0200nMAssay Description:Raf and biotinylated Mek, kinase dead, were combined at 2× final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0500nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0800nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0800nMpH: 7.5Assay Description:Raf/Mek amplified luminescence proximity homogeneous assay.More data for this Ligand-Target Pair
Affinity DataIC50: 0.0800nMpH: 7.5Assay Description:Raf/Mek amplified luminescence proximity homogeneous assay.More data for this Ligand-Target Pair
Affinity DataIC50: 0.100nMpH: 7.5Assay Description:Raf/Mek amplified luminescence proximity homogeneous assay.More data for this Ligand-Target Pair
Affinity DataIC50: 0.100nMpH: 7.5Assay Description:Raf/Mek amplified luminescence proximity homogeneous assay.More data for this Ligand-Target Pair
Affinity DataIC50: 0.100nMpH: 7.5Assay Description:Raf/Mek amplified luminescence proximity homogeneous assay.More data for this Ligand-Target Pair
Affinity DataIC50: 0.100nMpH: 7.5Assay Description:Raf/Mek amplified luminescence proximity homogeneous assay.More data for this Ligand-Target Pair
Affinity DataIC50: 0.100nMpH: 7.5Assay Description:Raf/Mek amplified luminescence proximity homogeneous assay.More data for this Ligand-Target Pair
Affinity DataIC50: 0.110nMpH: 7.5Assay Description:Raf/Mek amplified luminescence proximity homogeneous assay.More data for this Ligand-Target Pair
Affinity DataIC50: 0.110nMpH: 7.5Assay Description:Raf/Mek amplified luminescence proximity homogeneous assay.More data for this Ligand-Target Pair
Affinity DataIC50: 0.120nMpH: 7.5Assay Description:Raf/Mek amplified luminescence proximity homogeneous assay.More data for this Ligand-Target Pair
Affinity DataIC50: 0.130nMpH: 7.5Assay Description:Raf/Mek amplified luminescence proximity homogeneous assay.More data for this Ligand-Target Pair
Affinity DataIC50: 0.130nMpH: 7.5Assay Description:Raf/Mek amplified luminescence proximity homogeneous assay.More data for this Ligand-Target Pair
Affinity DataIC50: 0.130nMpH: 7.5Assay Description:Raf/Mek amplified luminescence proximity homogeneous assay.More data for this Ligand-Target Pair
Affinity DataIC50: 0.150nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair
Affinity DataIC50: 0.150nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair
Affinity DataIC50: 0.152nMAssay Description:C-Raf TR refers to a truncated C-Raf protein, a Δ1-324 deletion mutant.C-Raf FL refers to the full-length C-Raf protein.Full length MEK1 with an...More data for this Ligand-Target Pair
Affinity DataIC50: 0.160nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair
Affinity DataIC50: 0.160nMpH: 7.5Assay Description:Raf/Mek amplified luminescence proximity homogeneous assay.More data for this Ligand-Target Pair
Affinity DataIC50: 0.180nMpH: 7.5Assay Description:Raf/Mek amplified luminescence proximity homogeneous assay.More data for this Ligand-Target Pair
Affinity DataIC50: 0.180nMpH: 7.5Assay Description:Raf/Mek amplified luminescence proximity homogeneous assay.More data for this Ligand-Target Pair
Affinity DataIC50: 0.190nMpH: 7.5Assay Description:Raf/Mek amplified luminescence proximity homogeneous assay.More data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMpH: 7.5Assay Description:Raf/Mek amplified luminescence proximity homogeneous assay.More data for this Ligand-Target Pair
Affinity DataKd: 0.200nMAssay Description:The assay is not in detail.More data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Raf and biotinylated Mek, kinase dead, were combined at 2× final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:C-Raf TR refers to a truncated C-Raf protein, a Δ1-324 deletion mutant.C-Raf FL refers to the full-length C-Raf protein.Full length MEK1 with an...More data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:The B-Raf kinase activity reaction was started by the addition of 10 μl piper well of 2×ATP (10 μM) diluted in assay buffer. After 3 hours,...More data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Raf and biotinylated Mek, kinase dead, were combined at 2× final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:B-Raf (V600E; 4 pM) and biotinylated Mek (kinase dead; 10 nM) were combined at 2× final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgC...More data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMpH: 7.5 T: 2°CAssay Description:Raf and biotinylated Mek, kinase dead, were combined at 2x final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMpH: 7.5Assay Description:Raf/Mek amplified luminescence proximity homogeneous assay.More data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMpH: 7.5Assay Description:Raf/Mek amplified luminescence proximity homogeneous assay.More data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMpH: 7.5Assay Description:Raf/Mek amplified luminescence proximity homogeneous assay.More data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:C-Raf TR refers to a truncated C-Raf protein, a Δ1-324 deletion mutant.C-Raf FL refers to the full-length C-Raf protein.Full length MEK1 with an...More data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Raf and biotinylated Mek, kinase dead, were combined at 2× final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:C-Raf TR refers to a truncated C-Raf protein, a Δ1-324 deletion mutant.C-Raf FL refers to the full-length C-Raf protein.Full length MEK1 with an...More data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Raf and biotinylated Mek, kinase dead, were combined at 2× final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:C-Raf TR refers to a truncated C-Raf protein, a Δ1-324 deletion mutant.C-Raf FL refers to the full-length C-Raf protein.Full length MEK1 with an...More data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMpH: 7.5 T: 2°CAssay Description:Raf and biotinylated Mek, kinase dead, were combined at 2x final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMpH: 7.5 T: 2°CAssay Description:Raf and biotinylated Mek, kinase dead, were combined at 2x final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...More data for this Ligand-Target Pair
Affinity DataKd: 0.200nMAssay Description:Kd is measured using surface plasmon resonance assays using a BIACORER-2000 or a BIACORE-3000 (BIAcore, Inc., Piscataway, NJ) at 25 C. with immobiliz...More data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMpH: 7.5 T: 2°CAssay Description:Raf and biotinylated Mek, kinase dead, were combined at 2x final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% BSA and 1 mM ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.220nMpH: 7.5Assay Description:Raf/Mek amplified luminescence proximity homogeneous assay.More data for this Ligand-Target Pair
Affinity DataIC50: 0.230nMpH: 7.5Assay Description:Raf/Mek amplified luminescence proximity homogeneous assay.More data for this Ligand-Target Pair
Affinity DataIC50: 0.230nMpH: 7.5Assay Description:Raf/Mek amplified luminescence proximity homogeneous assay.More data for this Ligand-Target Pair
Affinity DataIC50: 0.240nMpH: 7.5Assay Description:Raf/Mek amplified luminescence proximity homogeneous assay.More data for this Ligand-Target Pair
