Compile Data Set for Download or QSAR
Report error Found 76 Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase pim-1/pim-2/pim-3'
LigandChemical structure of BindingDB Monomer ID 238767BDBM238767(US9394297, 451)
Affinity DataIC50: 11nMAssay Description:Inhibition of pan Pim in human KMS-12-BM cells assessed as reduction in phosphorylation of biotinylated-BAD peptide at Serine 112 residue after 110 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50518520BDBM50518520(CHEMBL4593810)
Affinity DataEC50:  13nMAssay Description:Inhibition of PIM in human KG1 cells assessed as reduction in pS6 levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50518510BDBM50518510(CHEMBL4448325)
Affinity DataEC50:  18nMAssay Description:Inhibition of PIM in human KG1 cells assessed as reduction in pS6 levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50536094BDBM50536094(CHEMBL4541192)
Affinity DataIC50: 22nMAssay Description:Inhibition of pan Pim in human KMS-12-BM cells assessed as reduction in phosphorylation of biotinylated-BAD peptide at Serine 112 residue after 110 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50536095BDBM50536095(CHEMBL4587596)
Affinity DataIC50: 23nMAssay Description:Inhibition of pan Pim in human KMS-12-BM cells assessed as reduction in phosphorylation of biotinylated-BAD peptide at Serine 112 residue after 110 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 238724BDBM238724(US9394297, 405)
Affinity DataIC50: 26nMAssay Description:Inhibition of pan Pim in human KMS-12-BM cells assessed as reduction in phosphorylation of biotinylated-BAD peptide at Serine 112 residue after 110 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50518517BDBM50518517(CHEMBL4540910)
Affinity DataEC50:  27nMAssay Description:Inhibition of PIM in human KG1 cells assessed as reduction in pS6 levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 192574BDBM192574(US9187486, 60 | US9187486, 39 | US9187486, 37)
Affinity DataIC50: 28nMAssay Description:Inhibition of Pim1/2 in human KMS-12 cells assessed as decrease in BAD phosphorylation at Ser112 by Western blot methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2018
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50518521BDBM50518521(CHEMBL4564586)
Affinity DataEC50:  28nMAssay Description:Inhibition of PIM in human KG1 cells assessed as reduction in pS6 levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 238637BDBM238637(US9394297, 297)
Affinity DataIC50: 29nMAssay Description:Inhibition of pan Pim in human KMS-12-BM cells assessed as reduction in phosphorylation of biotinylated-BAD peptide at Serine 112 residue after 110 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 238664BDBM238664(US9394297, 326)
Affinity DataIC50: 30nMAssay Description:Inhibition of pan Pim in human KMS-12-BM cells assessed as reduction in phosphorylation of biotinylated-BAD peptide at Serine 112 residue after 110 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50200531BDBM50200531(CHEMBL3950251)
Affinity DataIC50: 31nMAssay Description:Inhibition of Pim1/2 in human KMS-12 cells assessed as decrease in BAD phosphorylation at Ser112 by Western blot methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2018
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 238766BDBM238766(US9394297, 450)
Affinity DataIC50: 31nMAssay Description:Inhibition of pan Pim in human KMS-12-BM cells assessed as reduction in phosphorylation of biotinylated-BAD peptide at Serine 112 residue after 110 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50518506BDBM50518506(CHEMBL4588948)
Affinity DataEC50:  32nMAssay Description:Inhibition of PIM in human KG1 cells assessed as reduction in pS6 levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50518519BDBM50518519(CHEMBL4457389)
Affinity DataEC50:  33nMAssay Description:Inhibition of PIM in human KG1 cells assessed as reduction in pS6 levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50518509BDBM50518509(CHEMBL4587382)
Affinity DataEC50:  36nMAssay Description:Inhibition of PIM in human KG1 cells assessed as reduction in pS6 levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50518518BDBM50518518(CHEMBL4470576)
Affinity DataEC50:  37nMAssay Description:Inhibition of PIM in human KG1 cells assessed as reduction in pS6 levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 238672BDBM238672(US9394297, 334)
Affinity DataIC50: 44nMAssay Description:Inhibition of pan Pim in human KMS-12-BM cells assessed as reduction in phosphorylation of biotinylated-BAD peptide at Serine 112 residue after 110 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 192593BDBM192593(US9187486, 65)
Affinity DataIC50: 45nMAssay Description:Inhibition of Pim1/2 in human KMS-12 cells assessed as decrease in BAD phosphorylation at Ser112 by Western blot methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2018
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 192642BDBM192642(US9187486, 87)
Affinity DataIC50: 49nMAssay Description:Inhibition of Pim1/2 in human KMS-12 cells assessed as decrease in BAD phosphorylation at Ser112 by Western blot methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2018
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50518513BDBM50518513(CHEMBL4528544)
Affinity DataEC50:  53nMAssay Description:Inhibition of PIM in human KG1 cells assessed as reduction in pS6 levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50518522BDBM50518522(CHEMBL4466080)
Affinity DataEC50:  59nMAssay Description:Inhibition of PIM in human KG1 cells assessed as reduction in pS6 levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50518512BDBM50518512(CHEMBL4541837)
Affinity DataEC50:  61nMAssay Description:Inhibition of PIM in human KG1 cells assessed as reduction in pS6 levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 238665BDBM238665(US9394297, 327)
Affinity DataIC50: 65nMAssay Description:Inhibition of pan Pim in human KMS-12-BM cells assessed as reduction in phosphorylation of biotinylated-BAD peptide at Serine 112 residue after 110 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50518504BDBM50518504(CHEMBL4466764)
Affinity DataEC50:  70nMAssay Description:Inhibition of PIM in human KG1 cells assessed as reduction in pS6 levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50518504BDBM50518504(CHEMBL4466764)
Affinity DataEC50:  70nMAssay Description:Inhibition of PIM in human KG1 cells assessed as reduction in pS6 levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 238662BDBM238662(US9394297, 324)
Affinity DataIC50: 78nMAssay Description:Inhibition of pan Pim in human KMS-12-BM cells assessed as reduction in phosphorylation of biotinylated-BAD peptide at Serine 112 residue after 110 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50536097BDBM50536097(CHEMBL4572195)
Affinity DataIC50: 88nMAssay Description:Inhibition of pan Pim in human KMS-12-BM cells assessed as reduction in phosphorylation of biotinylated-BAD peptide at Serine 112 residue after 110 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50518516BDBM50518516(CHEMBL4445116)
Affinity DataEC50:  90nMAssay Description:Inhibition of PIM in human KG1 cells assessed as reduction in pS6 levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50518515BDBM50518515(CHEMBL4446498)
Affinity DataEC50:  93nMAssay Description:Inhibition of PIM in human KG1 cells assessed as reduction in pS6 levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50518511BDBM50518511(CHEMBL4457529)
Affinity DataEC50:  98nMAssay Description:Inhibition of PIM in human KG1 cells assessed as reduction in pS6 levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 238547BDBM238547(US9394297, 193)
Affinity DataIC50: 110nMAssay Description:Inhibition of pan Pim in human KMS-12-BM cells assessed as reduction in phosphorylation of biotinylated-BAD peptide at Serine 112 residue after 110 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50200533BDBM50200533(CHEMBL3904539)
Affinity DataIC50: 115nMAssay Description:Inhibition of Pim1/2 in human KMS-12 cells assessed as decrease in BAD phosphorylation at Ser112 by Western blot methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2018
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50536098BDBM50536098(CHEMBL4587256)
Affinity DataIC50: 127nMAssay Description:Inhibition of pan Pim in human KMS-12-BM cells assessed as reduction in phosphorylation of biotinylated-BAD peptide at Serine 112 residue after 110 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50518514BDBM50518514(CHEMBL4563802)
Affinity DataEC50:  128nMAssay Description:Inhibition of PIM in human KG1 cells assessed as reduction in pS6 levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50518508BDBM50518508(CHEMBL4533366)
Affinity DataEC50:  133nMAssay Description:Inhibition of PIM in human KG1 cells assessed as reduction in pS6 levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50518505BDBM50518505(CHEMBL4518492)
Affinity DataEC50:  137nMAssay Description:Inhibition of PIM in human KG1 cells assessed as reduction in pS6 levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50518505BDBM50518505(CHEMBL4518492)
Affinity DataEC50:  137nMAssay Description:Inhibition of PIM in human KG1 cells assessed as reduction in pS6 levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 192640BDBM192640(US9187486, 85)
Affinity DataIC50: 142nMAssay Description:Inhibition of Pim1/2 in human KMS-12 cells assessed as decrease in BAD phosphorylation at Ser112 by Western blot methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2018
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 238706BDBM238706(US9394297, 370)
Affinity DataIC50: 143nMAssay Description:Inhibition of pan Pim in human KMS-12-BM cells assessed as reduction in phosphorylation of biotinylated-BAD peptide at Serine 112 residue after 110 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 238707BDBM238707(US9394297, 371)
Affinity DataIC50: 148nMAssay Description:Inhibition of pan Pim in human KMS-12-BM cells assessed as reduction in phosphorylation of biotinylated-BAD peptide at Serine 112 residue after 110 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50536092BDBM50536092(CHEMBL4589855)
Affinity DataIC50: 167nMAssay Description:Inhibition of pan Pim in human KMS-12-BM cells assessed as reduction in phosphorylation of biotinylated-BAD peptide at Serine 112 residue after 110 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 192648BDBM192648(US9187486, 100)
Affinity DataIC50: 212nMAssay Description:Inhibition of Pim1/2 in human KMS-12 cells assessed as decrease in BAD phosphorylation at Ser112 by Western blot methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2018
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 192586BDBM192586(US9187486, 54)
Affinity DataIC50: 221nMAssay Description:Inhibition of Pim1/2 in human KMS-12 cells assessed as decrease in BAD phosphorylation at Ser112 by Western blot methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2018
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 192645BDBM192645(US9187486, 96)
Affinity DataIC50: 258nMAssay Description:Inhibition of Pim1/2 in human KMS-12 cells assessed as decrease in BAD phosphorylation at Ser112 by Western blot methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2018
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50518507BDBM50518507(CHEMBL4583118)
Affinity DataEC50:  283nMAssay Description:Inhibition of PIM in human KG1 cells assessed as reduction in pS6 levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50518507BDBM50518507(CHEMBL4583118)
Affinity DataEC50:  283nMAssay Description:Inhibition of PIM in human KG1 cells assessed as reduction in pS6 levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 192577BDBM192577(US9187486, 40)
Affinity DataIC50: 286nMAssay Description:Inhibition of Pim1/2 in human KMS-12 cells assessed as decrease in BAD phosphorylation at Ser112 by Western blot methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2018
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 192539BDBM192539(US9187486, 1)
Affinity DataIC50: 403nMAssay Description:Inhibition of Pim1/2 in human KMS-12 cells assessed as decrease in BAD phosphorylation at Ser112 by Western blot methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2018
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 238771BDBM238771(US9394297, 455)
Affinity DataIC50: 407nMAssay Description:Inhibition of pan Pim in human KMS-12-BM cells assessed as reduction in phosphorylation of biotinylated-BAD peptide at Serine 112 residue after 110 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
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