Compile Data Set for Download or QSAR
Report error Found 11043 Enz. Inhib. hit(s) with Target = 'Sodium-dependent dopamine transporter'
TargetSodium-dependent dopamine transporter(Rat)
State University of New York

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50051753BDBM50051753(1-(3-Naphthalen-2-yl-8-aza-bicyclo[3.2.1]oct-2-yl)...)
Affinity DataIC50: 0.0300nMAssay Description:Inhibitory activity in displacing [125I]- RTI-55 binding to dopamine transporter in rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
State University of New York

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50007404BDBM50007404(CHEMBL113621 | 1-(3-Chloro-phenyl)-4-phenethyl-pip...)
Affinity DataKi:  0.0400nMAssay Description:Displacement of [3H]WIN 35428 from dopamine transporter in rat striatum after 120 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
State University of New York

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50041293BDBM50041293(WF-23 | CHEMBL418190 | 1-(8-Methyl-3-naphthalen-2-...)
Affinity DataIC50: 0.0430nMAssay Description:Inhibition of [125I]RTI-55 binding to dopamine transport sites in rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
State University of New York

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 22165BDBM22165(Vanoxerine | CHEMBL542933 | GBR-12909 | CHEMBL5438...)
Affinity DataKi:  0.0600nMAssay Description:In vitro binding affinity towards dopamine transporter in rat striatal membranes by [3H]GBR-12395 displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium-dependent dopamine transporter(Rat)
State University of New York

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50111889BDBM50111889(1-[3-(3-Chloro-4-iodo-phenyl)-8-methyl-8-aza-bicyc...)
Affinity DataIC50: 0.0770nMAssay Description:Tested for the ability to displace [125I]- RTI-55 binding in rat striatal membrane against dopamine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
State University of New York

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50111893BDBM50111893(1-[3-(3-Chloro-4-iodo-phenyl)-8-aza-bicyclo[3.2.1]...)
Affinity DataIC50: 0.0850nMAssay Description:Tested for the ability to displace [125I]- RTI-55 binding in rat striatal membrane against dopamine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
State University of New York

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50041293BDBM50041293(WF-23 | CHEMBL418190 | 1-(8-Methyl-3-naphthalen-2-...)
Affinity DataIC50: 0.115nMAssay Description:Inhibition of [125I]RTI-55 binding to dopamine transport sites in rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
State University of New York

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50041293BDBM50041293(WF-23 | CHEMBL418190 | 1-(8-Methyl-3-naphthalen-2-...)
Affinity DataIC50: 0.120nMAssay Description:Displacement of [125I]RTI-55 from dopamine transporter of rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
State University of New York

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50099235BDBM50099235(1-[3-(6-Methoxy-naphthalen-2-yl)-8-methyl-8-aza-bi...)
Affinity DataIC50: 0.130nMAssay Description:Inhibitory activity in displacing [125I]- RTI-55 binding to dopamine transporter in rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
State University of New York

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50494706BDBM50494706(CHEMBL3093268)
Affinity DataKi:  0.130nMAssay Description:Displacement of [3H]WIN 35428 from dopamine transporter in rat striatum after 120 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
State University of New York

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50041293BDBM50041293(WF-23 | CHEMBL418190 | 1-(8-Methyl-3-naphthalen-2-...)
Affinity DataKi:  0.140nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2012
Entry Details
PubMed
TargetSodium-dependent dopamine transporter(Rat)
State University of New York

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50032539BDBM50032539((2S,3S)-3-(4-Chloro-phenyl)-8-methyl-2-((Z)-styryl...)
Affinity DataKi:  0.140nMAssay Description:Binding affinity towards dopamine transporter using [3H]-mazindol as radioligand in rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Institut F£R Bioanorganische Und Radiopharmazeutische Chemie

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50067772BDBM50067772(Rhenium complex of 3-(2-Bromo-2,2,2-triformyl-3-me...)
Affinity DataIC50: 0.146nMAssay Description:The compound was tested in vitro for high binding affinity for the Dopamine transporter (DAT) using competitive binding assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
State University of New York

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 22165BDBM22165(Vanoxerine | CHEMBL542933 | GBR-12909 | CHEMBL5438...)
Affinity DataKi:  0.150nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium-dependent dopamine transporter(Rat)
State University of New York

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50099227BDBM50099227(1-[3-(6-Ethyl-naphthalen-2-yl)-8-methyl-8-aza-bicy...)
Affinity DataIC50: 0.150nMAssay Description:Inhibitory activity in displacing [125I]- RTI-55 binding to dopamine transporter in rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
State University of New York

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50021226BDBM50021226(CHEMBL296602 | Indatraline | [3-(3,4-Dichloro-phen...)
Affinity DataIC50: 0.170nMAssay Description:Inhibition of dopamine uptake in rat synaptosomal fractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
State University of New York

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50021226BDBM50021226(CHEMBL296602 | Indatraline | [3-(3,4-Dichloro-phen...)
Affinity DataIC50: 0.170nMAssay Description:Inhibition of dopamine uptake in rat synaptosomal fractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Institut F£R Bioanorganische Und Radiopharmazeutische Chemie

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50101075BDBM50101075((2S,3S)-methyl 3-(3,4-dichlorophenyl)-8-methyl-8-a...)
Affinity DataKi:  0.200nMAssay Description:Displacement of [3H]CFT from human DAT expressed in COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Institut F£R Bioanorganische Und Radiopharmazeutische Chemie

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004167BDBM50004167((2R,3S)-3-(4-Chloro-phenyl)-2-((E)-2-chloro-vinyl)...)
Affinity DataKi:  0.220nMAssay Description:Binding constant for the ability to displace [3H]mazindol to dopamine receptor was calculated from the Cheng-Prusoff relationshipMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetSodium-dependent dopamine transporter(Rat)
State University of New York

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50032536BDBM50032536((2R,3S)-3-(4-Chloro-phenyl)-2-((Z)-2-chloro-vinyl)...)
Affinity DataKi:  0.220nMAssay Description:Binding affinity towards dopamine transporter using [3H]-mazindol as radioligand in rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Institut F£R Bioanorganische Und Radiopharmazeutische Chemie

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50067771BDBM50067771(3-(2-Methylsulfanyl-ethylsulfanyl)-propionic acid ...)
Affinity DataIC50: 0.227nMAssay Description:The compound was tested in vitro for high binding affinity for the Dopamine transporter (DAT) using competitive binding assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Institut F£R Bioanorganische Und Radiopharmazeutische Chemie

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50260904BDBM50260904((1R,2R,3S,5S)-2-(2,2-dibromovinyl)-8-methyl-3-p-to...)
Affinity DataIC50: 0.230nMAssay Description:Displacement of [3H]WIN-35428 from dopamine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
State University of New York

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50099225BDBM50099225(2-Methyl-1-(8-methyl-3-naphthalen-2-yl-8-aza-bicyc...)
Affinity DataIC50: 0.25nMAssay Description:Inhibitory activity in displacing [125I]- RTI-55 binding to dopamine transporter in rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
State University of New York

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50055014BDBM50055014(7-(3,4-Dichloro-phenyl)-2,4,5,7-tetrahydro-3H-[1,3...)
Affinity DataIC50: 0.260nMAssay Description:Inhibition of [3H]dopamine uptake at the dopamine transporter in rat striatal tissueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
State University of New York

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50041304BDBM50041304(1-(8-Methyl-3-naphthalen-2-yl-8-aza-bicyclo[3.2.1]...)
Affinity DataIC50: 0.280nMAssay Description:Inhibition of [125I]RTI-55 binding to dopamine transport sites in rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
State University of New York

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035766BDBM50035766(3-(4-Bromo-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]oc...)
Affinity DataKi:  0.300nMAssay Description:Displacement of [3H]CIT from dopamine transporter of rat striatal homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Crab-eating macaque)
Organix

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50197470BDBM50197470((1S,2S,3S,7R)-methyl 3-(3,4-dichlorophenyl)-7-hydr...)
Affinity DataIC50: 0.300nMAssay Description:Displacement of [3H]WIN-35428 from DAT in rhesus monkey caudate-putamenMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
State University of New York

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043303BDBM50043303((1-Benzo[b]thiophen-2-yl-cyclohexyl)-butyl-amine |...)
Affinity DataIC50: 0.300nMAssay Description:Tested for radioligand [3H]BTCP displacement from dopamine transporter in rat forebrainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Institut F£R Bioanorganische Und Radiopharmazeutische Chemie

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50102589BDBM50102589(3-(3,4-Dichloro-phenyl)-7-hydroxy-8-methyl-8-aza-b...)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of [3H]WIN-35428 binding to Dopamine transporter in rhesus (Macaca mulatta) or cynomolgus monkey (Macaca fascicularis) caudate-putamenMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
State University of New York

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50032534BDBM50032534((2S,3S)-3-(4-Chloro-phenyl)-8-methyl-2-((E)-styryl...)
Affinity DataKi:  0.310nMAssay Description:Binding affinity towards dopamine transporter using [3H]-mazindol as radioligand in rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
State University of New York

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50032539BDBM50032539((2S,3S)-3-(4-Chloro-phenyl)-8-methyl-2-((Z)-styryl...)
Affinity DataKi:  0.310nMAssay Description:Inhibition of [3H]dopamine binding to rat striatal synaptosome dopamine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Institut F£R Bioanorganische Und Radiopharmazeutische Chemie

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50260905BDBM50260905((1R,2R,3S,5S)-3-(4-chlorophenyl)-2-(2,2-dibromovin...)
Affinity DataIC50: 0.320nMAssay Description:Displacement of [3H]WIN-35428 from dopamine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
State University of New York

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50099228BDBM50099228(1-[3-(6-Iodo-naphthalen-2-yl)-8-methyl-8-aza-bicyc...)
Affinity DataIC50: 0.350nMAssay Description:Inhibitory activity in displacing [125I]- RTI-55 binding to dopamine transporter in rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Institut F£R Bioanorganische Und Radiopharmazeutische Chemie

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50085072BDBM50085072(GBR-12909 | 1-{2-[(3-Fluoro-phenyl)-(4-fluoro-phen...)
Affinity DataKi:  0.360nMAssay Description:Competitive binding versus [N-methyl-3H]WIN-35428 in murine kidney cells transfected with human dopamine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Institut F£R Bioanorganische Und Radiopharmazeutische Chemie

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004167BDBM50004167((2R,3S)-3-(4-Chloro-phenyl)-2-((E)-2-chloro-vinyl)...)
Affinity DataIC50: 0.360nMAssay Description:Displacement of [3H]mazindol from dopamine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetSodium-dependent dopamine transporter(Human)
Institut F£R Bioanorganische Und Radiopharmazeutische Chemie

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50004167BDBM50004167((2R,3S)-3-(4-Chloro-phenyl)-2-((E)-2-chloro-vinyl)...)
Affinity DataIC50: 0.360nMAssay Description:Displacement of [3H]mazindol from dopamine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetSodium-dependent dopamine transporter(Rat)
State University of New York

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50334460BDBM50334460(RTI-229 | CHEMBL1643896 | ((1R,2S,3S,5S)-3-(4-iodo...)
Affinity DataKi:  0.370nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2012
Entry Details
PubMed
TargetSodium-dependent dopamine transporter(Rat)
State University of New York

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035734BDBM50035734([3-(4-Iodo-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]oc...)
Affinity DataIC50: 0.370nMAssay Description:Binding affinity at the Dopamine transporter in rat striata by inhibition of 0.5 nM [3H]WIN-35428 bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Institut F£R Bioanorganische Und Radiopharmazeutische Chemie

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50334460BDBM50334460(RTI-229 | CHEMBL1643896 | ((1R,2S,3S,5S)-3-(4-iodo...)
Affinity DataIC50: 0.370nMAssay Description:Inhibition of DATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
State University of New York

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035734BDBM50035734([3-(4-Iodo-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]oc...)
Affinity DataIC50: 0.370nMAssay Description:Inhibition of [3H]WIN-35428 binding at dopamine transporter was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Crab-eating macaque)
Organix

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035730BDBM50035730(3-(3,4-Dichloro-phenyl)-8-methyl-8-aza-bicyclo[3.2...)
Affinity DataIC50: 0.380nMAssay Description:Inhibition of [3H]WIN-35428 binding to dopamine transporter (DAT) of cynomolgus monkey caudate-putamenMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Crab-eating macaque)
Organix

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035730BDBM50035730(3-(3,4-Dichloro-phenyl)-8-methyl-8-aza-bicyclo[3.2...)
Affinity DataIC50: 0.380nMAssay Description:Inhibition of [3H]WIN-35428 binding to dopamine transporter (DAT) of cynomolgus monkey caudate-putamenMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
State University of New York

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50111888BDBM50111888(1-[3-(3-Fluoro-4-iodo-phenyl)-8-methyl-8-aza-bicyc...)
Affinity DataIC50: 0.380nMAssay Description:Tested for the ability to displace [125I]- RTI-55 binding in rat striatal membrane against dopamine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
State University of New York

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50099233BDBM50099233(1-[3-(6-Isopropyl-naphthalen-2-yl)-8-methyl-8-aza-...)
Affinity DataIC50: 0.390nMAssay Description:Inhibitory activity in displacing [125I]- RTI-55 binding to dopamine transporter in rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Mouse)
Mcneil Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50014237BDBM50014237(CHEMBL327790 | 6-(4-Methylsulfanyl-phenyl)-1,2,3,5...)
Affinity DataKi:  0.390nMAssay Description:Tested in vitro for serotonin(5-HT) neuronal uptake inhibitionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Crab-eating macaque)
Organix

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50197437BDBM50197437((1R,2S,3R)-methyl 3-(3,4-dichlorophenyl)-8-methyl-...)
Affinity DataIC50: 0.400nMAssay Description:Displacement of [3H]WIN-35428 from DAT in rhesus monkey caudate-putamenMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Institut F£R Bioanorganische Und Radiopharmazeutische Chemie

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50183549BDBM50183549((S)-(+)-4-[2-[bis-(4-fluorophenyl)methoxy]ethyl]-1...)
Affinity DataKi:  0.400nMAssay Description:Displacement of [125I]RTI-55 from DATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Institut F£R Bioanorganische Und Radiopharmazeutische Chemie

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50323773BDBM50323773(N-((E)-4-Fluorobut-2-en-1-yl)-2beta-carbomethoxy-3...)
Affinity DataKi:  0.400nMAssay Description:Displacement of [125I]RTI55 from human DATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
State University of New York

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50006784BDBM50006784(CHEMBL82946 | RTI-121 | 3-(4-Iodo-phenyl)-8-methyl...)
Affinity DataKi:  0.400nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2012
Entry Details
PubMed
TargetSodium-dependent dopamine transporter(Human)
Institut F£R Bioanorganische Und Radiopharmazeutische Chemie

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035730BDBM50035730(3-(3,4-Dichloro-phenyl)-8-methyl-8-aza-bicyclo[3.2...)
Affinity DataIC50: 0.400nMAssay Description:inhibition of [3H]WIN-35428 binding to the dopamine transporter (DAT) in monkey caudate-putamen.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2012
Entry Details Article
PubMed
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