Compile Data Set for Download or QSAR
Report error Found 70 Enz. Inhib. hit(s) with Target = 'Sphingomyelin phosphodiesterase 2'
TargetSphingomyelin phosphodiesterase 2(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50407385BDBM50407385(CHEMBL5284450)
Affinity DataIC50: 300nMAssay Description:Inhibition of human recombinant nSMaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetSphingomyelin phosphodiesterase 2(Mouse)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50407382BDBM50407382(CHEMBL5280187)
Affinity DataIC50: 860nMAssay Description:Inhibition of mouse nSMaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetSphingomyelin phosphodiesterase 2(Mouse)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50407379BDBM50407379(CHEMBL5276486)
Affinity DataIC50: 900nMAssay Description:Inhibition of mouse nSMaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetSphingomyelin phosphodiesterase 2(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100341BDBM50100341((2E,4E,6E,12E)-(8R,10S,14R)-8,10,12,14-Tetramethyl...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory concentration against the membrane neutral magnesium-dependent Sphingomyelinase (N-SMase) using rat brain microsomes as the enzyme sourceMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 2(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100341BDBM50100341((2E,4E,6E,12E)-(8R,10S,14R)-8,10,12,14-Tetramethyl...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of rat brain microsomes nSMaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetSphingomyelin phosphodiesterase 2(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50407378BDBM50407378(CHEMBL1514251)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of rat brain nSMaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetSphingomyelin phosphodiesterase 2(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100341BDBM50100341((2E,4E,6E,12E)-(8R,10S,14R)-8,10,12,14-Tetramethyl...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity against neutral sphingomyelinase (N-SMase) from bovine brain microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 2(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50407383BDBM50407383(CHEMBL5278618)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human recombinant nSMaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetSphingomyelin phosphodiesterase 2(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50122309BDBM50122309(((3S,4R)-1,1-Difluoro-3-hexadecanoylamino-4-hydrox...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity against schyphostatin of neutral sphingomyelinase (N-SMase) from bovine brain microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 2(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100341BDBM50100341((2E,4E,6E,12E)-(8R,10S,14R)-8,10,12,14-Tetramethyl...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory concentration against neutral sphingomyelinase (N-Smase) from rat brain microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 2(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50122309BDBM50122309(((3S,4R)-1,1-Difluoro-3-hexadecanoylamino-4-hydrox...)
Affinity DataKi:  1.60E+3nMAssay Description:Inhibitory activity against neutral sphingomyelinase (N-SMase) from bovine brain microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 2(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50128902BDBM50128902(Pyridin-4-ylmethyl-carbamic acid (E)-(2S,3R)-3-hyd...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of rat brain microsomes nSMaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetSphingomyelin phosphodiesterase 2(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50407376BDBM50407376(CHEMBL5284579)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of nSMase in human U-937 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetSphingomyelin phosphodiesterase 2(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50128902BDBM50128902(Pyridin-4-ylmethyl-carbamic acid (E)-(2S,3R)-3-hyd...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibitory concentration against the membrane neutral magnesium-dependent Sphingomyelinase (N-SMase) using rat brain microsomes as the enzyme sourceMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 2(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50128892BDBM50128892(Pyridin-3-ylmethyl-carbamic acid (E)-(2S,3R)-2-(2,...)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibitory concentration against the membrane neutral magnesium-dependent Sphingomyelinase (N-SMase) using rat brain microsomes as the enzyme sourceMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 2(Mouse)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50407381BDBM50407381(CHEMBL5285219)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of mouse nSMaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetSphingomyelin phosphodiesterase 2(Mouse)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50407380BDBM50407380(CHEMBL5279211)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of mouse nSMaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetSphingomyelin phosphodiesterase 2(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50128891BDBM50128891(Pyridin-4-ylmethyl-carbamic acid (E)-(2S,3R)-2-(2,...)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibitory activity against N-SMase (neutral magnesium- dependent-sphingomyelinase) using rat brain microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 2(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50407377BDBM50407377(CHEMBL5270975)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of nSMase in human U-937 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetSphingomyelin phosphodiesterase 2(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50128891BDBM50128891(Pyridin-4-ylmethyl-carbamic acid (E)-(2S,3R)-2-(2,...)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibitory concentration against the membrane neutral magnesium-dependent Sphingomyelinase (N-SMase) using rat brain microsomes as the enzyme sourceMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 2(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50128891BDBM50128891(Pyridin-4-ylmethyl-carbamic acid (E)-(2S,3R)-2-(2,...)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of rat brain microsomes nSMaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetSphingomyelin phosphodiesterase 2(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50134343BDBM50134343(N-[(E)-(1S,2R)-2-Hydroxy-1-(3-pyridin-4-ylmethyl-u...)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibitory activity against N-SMase (neutral magnesium- dependent-sphingomyelinase) using rat brain microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 2(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50128908BDBM50128908((2-Dimethylamino-ethyl)-carbamic acid (E)-(2S,3R)-...)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibitory concentration against the membrane neutral magnesium-dependent Sphingomyelinase (N-SMase) using rat brain microsomes as the enzyme sourceMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 2(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50407375BDBM50407375(CHEMBL5285849)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of rat brain microsomes nSMaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetSphingomyelin phosphodiesterase 2(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50128903BDBM50128903((3-Dimethylamino-propyl)-carbamic acid (E)-(2S,3R)...)
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibitory concentration against the membrane neutral magnesium-dependent Sphingomyelinase (N-SMase) using rat brain microsomes as the enzyme sourceMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 2(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50128898BDBM50128898(Pyridin-2-ylmethyl-carbamic acid (E)-(2S,3R)-2-(2,...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibitory concentration against the membrane neutral magnesium-dependent Sphingomyelinase (N-SMase) using rat brain microsomes as the enzyme sourceMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 2(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50407373BDBM50407373(CHEMBL2365779)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of rat brain microsomes nSMaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetSphingomyelin phosphodiesterase 2(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50134339BDBM50134339(Pyridin-4-ylmethyl-carbamic acid (E)-(2S,3R)-2-(2,...)
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibitory activity against N-SMase (neutral magnesium- dependent-sphingomyelinase) using rat brain microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 2(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50134340BDBM50134340(Pyridin-4-ylmethyl-carbamic acid (E)-(2S,3R)-2-(2,...)
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibitory activity against N-SMase (neutral magnesium- dependent-sphingomyelinase) using rat brain microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 2(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50128906BDBM50128906(Pyridin-2-yl-carbamic acid (E)-(2S,3R)-2-(2,2-dime...)
Affinity DataIC50: 7.90E+3nMAssay Description:Inhibitory concentration against the membrane neutral magnesium-dependent Sphingomyelinase (N-SMase) using rat brain microsomes as the enzyme sourceMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 2(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50407371BDBM50407371(CHEMBL5284730)
Affinity DataIC50: 8.20E+3nMAssay Description:Inhibition of rat brain microsomes nSMaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetSphingomyelin phosphodiesterase 2(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50128905BDBM50128905((4-Dimethylamino-benzyl)-carbamic acid (E)-(2S,3R)...)
Affinity DataIC50: 8.20E+3nMAssay Description:Inhibitory concentration against the membrane neutral magnesium-dependent Sphingomyelinase (N-SMase) using rat brain microsomes as the enzyme sourceMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 2(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50128900BDBM50128900((2-Pyridin-2-yl-ethyl)-carbamic acid (E)-(2S,3R)-2...)
Affinity DataIC50: 8.40E+3nMAssay Description:Inhibitory concentration against the membrane neutral magnesium-dependent Sphingomyelinase (N-SMase) using rat brain microsomes as the enzyme sourceMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 2(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50128896BDBM50128896({2-[(E)-(2S,3R)-2-(2,2-Dimethyl-propionylamino)-3-...)
Affinity DataIC50: 8.70E+3nMAssay Description:Inhibitory concentration against the membrane neutral magnesium-dependent Sphingomyelinase (N-SMase) using rat brain microsomes as the enzyme sourceMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 2(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50407370BDBM50407370(CHEMBL5281448)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of rat brain microsomes nSMaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetSphingomyelin phosphodiesterase 2(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50407369BDBM50407369(CHEMBL5288641)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of rat brain microsomes nSMaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetSphingomyelin phosphodiesterase 2(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50128904BDBM50128904((2-Diisopropylamino-ethyl)-carbamic acid (E)-(2S,3...)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibitory concentration against the membrane neutral magnesium-dependent Sphingomyelinase (N-SMase) using rat brain microsomes as the enzyme sourceMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 2(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50576BDBM50576(4-methoxy-2-[2-methyl-4,5-bis(oxidanyl)phenyl]-6-o...)
Affinity DataKi:  2.00E+4nMAssay Description:Inhibition of rat brain microsomes nSMase assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetSphingomyelin phosphodiesterase 2(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50134345BDBM50134345((2S,3R)-2-[(2,2-dimethylpropanoyl)amino]-3-hydroxy...)
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibitory activity against N-SMase (neutral magnesium- dependent-sphingomyelinase) using rat brain microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 2(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50221658BDBM50221658(CHEMBL110491)
Affinity DataIC50: 2.59E+4nMAssay Description:Inhibitory activity against NSMase (neutral sphingomyelinase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2018
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 2(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50221662BDBM50221662(CHEMBL320658)
Affinity DataIC50: 2.77E+4nMAssay Description:Inhibitory activity against NSMase (neutral sphingomyelinase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2018
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 2(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50128895BDBM50128895(4-Dimethylamino-butyric acid (E)-(2S,3R)-2-(2,2-di...)
Affinity DataIC50: 3.10E+4nMAssay Description:Inhibitory concentration against the membrane neutral magnesium-dependent Sphingomyelinase (N-SMase) using rat brain microsomes as the enzyme sourceMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 2(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50407368BDBM50407368(CHEMBL444672)
Affinity DataIC50: 3.40E+4nMAssay Description:Inhibition of rat brain microsomes nSMaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetSphingomyelin phosphodiesterase 2(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50134344BDBM50134344(N-[(E)-(1S,2R)-2-Hydroxy-1-(3-pyridin-4-ylmethyl-t...)
Affinity DataIC50: 4.50E+4nMAssay Description:Inhibitory activity against N-SMase (neutral magnesium- dependent-sphingomyelinase) using rat brain microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 2(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100341BDBM50100341((2E,4E,6E,12E)-(8R,10S,14R)-8,10,12,14-Tetramethyl...)
Affinity DataIC50: 4.93E+4nMAssay Description:Inhibitory concentration against neutral sphingomyelinase (N-Smase) from rat brain microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 2(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50134341BDBM50134341([(E)-(2S,3R)-2-(2,2-Dimethyl-propionylamino)-3-hyd...)
Affinity DataIC50: 5.80E+4nMAssay Description:Inhibitory activity against N-SMase (neutral magnesium- dependent-sphingomyelinase) using rat brain microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 2(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50128897BDBM50128897((3,3-Dimethyl-butyl)-carbamic acid (E)-(2S,3R)-2-(...)
Affinity DataIC50: 7.70E+4nMAssay Description:Inhibitory concentration against the membrane neutral magnesium-dependent Sphingomyelinase (N-SMase) using rat brain microsomes as the enzyme sourceMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 2(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50128899BDBM50128899((S)-Pyridin-4-ylmethyl-carbamic acid (R)-2-amino-3...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory concentration against the membrane neutral magnesium-dependent Sphingomyelinase (N-SMase) using rat brain microsomes as the enzyme sourceMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 2(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50308979BDBM50308979(6-O-Dodecylsulfonyl-D-glucose-2,4-bisphosphate | C...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of nSMase in rat brain microsomal homogenate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 2(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50128901BDBM50128901(Pyridin-4-ylmethyl-carbamic acid (E)-(2S,3R)-3-hyd...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of rat brain microsomes nSMaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
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