Compile Data Set for Download or QSAR
Report error Found 330 Enz. Inhib. hit(s) with Target = 'Stimulator of interferon genes protein [1-379,R71H,G230A,H232R,R293Q]'
LigandChemical structure of BindingDB Monomer ID 457789BDBM457789(US10738074, Example 19)
Affinity DataEC50: <1nMAssay Description:16 nM of [3H] c-GAMP ligand was prepared by diluting into assay buffer, and 50 uL of this working stock was manually added to each well of the assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 457790BDBM457790(US10738074, Example 20)
Affinity DataEC50: <1nMAssay Description:16 nM of [3H] c-GAMP ligand was prepared by diluting into assay buffer, and 50 uL of this working stock was manually added to each well of the assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 573876BDBM573876(US11453697, Example 71 | 2-amino-9- [(5R,7R,8R,12a...)
Affinity DataEC50: <1nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 573996BDBM573996(US11453697, Example 314 | 2-amino-9- [(5R,7R,8S,12...)
Affinity DataEC50: <1nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 457787BDBM457787(US10738074, Example 18)
Affinity DataEC50: <1nMAssay Description:16 nM of [3H] c-GAMP ligand was prepared by diluting into assay buffer, and 50 uL of this working stock was manually added to each well of the assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 573874BDBM573874(US11453697, Example 69 | 5-amino-3- [(5R,7R,8R,12a...)
Affinity DataEC50: <1nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 573999BDBM573999(US11453697, Example 317 | 2-amino-9- [(2R,5S,7R,8R...)
Affinity DataEC50: <1nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 573877BDBM573877(US11453697, Example 72 | 2-amino-9- [(5R,7R,8R,12a...)
Affinity DataEC50: <1nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 457780BDBM457780(2-amino-9-[(1S,6R,8R,9S,14R,16R,17R,18R)-16- (6-am...)
Affinity DataEC50: <1nMAssay Description:16 nM of [3H] c-GAMP ligand was prepared by diluting into assay buffer, and 50 uL of this working stock was manually added to each well of the assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 457774BDBM457774(2-amino-9-[(1R,6S,8R,9R,14R,16R,17R,18R)-16- (6-am...)
Affinity DataEC50: <1nMAssay Description:16 nM of [3H] c-GAMP ligand was prepared by diluting into assay buffer, and 50 uL of this working stock was manually added to each well of the assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 573859BDBM573859(US11453697, Example 23 | US11453697, Example 26 | ...)
Affinity DataEC50: <1nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 573979BDBM573979(US11453697, Example 297 | 2-amino-9- [(2R,5R,7R,8R...)
Affinity DataEC50: <1nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 573985BDBM573985(US11453697, Example 303 | 2-amino-9- [(5R,7R,8S,12...)
Affinity DataEC50: <1nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 573859BDBM573859(US11453697, Example 23 | US11453697, Example 26 | ...)
Affinity DataEC50: <1nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 573989BDBM573989(US11453697, Example 307 | 2-amino-9-[(2R,5R,7R,8S,...)
Affinity DataEC50: <1nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 457797BDBM457797(US10738074, Example 34)
Affinity DataEC50: <1nMAssay Description:16 nM of [3H] c-GAMP ligand was prepared by diluting into assay buffer, and 50 uL of this working stock was manually added to each well of the assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 457792BDBM457792(US10738074, Example 25 | 9,9′-[(1R,6R,8R,9R,...)
Affinity DataEC50: <1nMAssay Description:16 nM of [3H] c-GAMP ligand was prepared by diluting into assay buffer, and 50 uL of this working stock was manually added to each well of the assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 457792BDBM457792(US10738074, Example 25 | 9,9′-[(1R,6R,8R,9R,...)
Affinity DataEC50: <1nMAssay Description:16 nM of [3H] c-GAMP ligand was prepared by diluting into assay buffer, and 50 uL of this working stock was manually added to each well of the assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 573876BDBM573876(US11453697, Example 71 | 2-amino-9- [(5R,7R,8R,12a...)
Affinity DataEC50: <1nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 573874BDBM573874(US11453697, Example 69 | 5-amino-3- [(5R,7R,8R,12a...)
Affinity DataEC50: <1nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 573877BDBM573877(US11453697, Example 72 | 2-amino-9- [(5R,7R,8R,12a...)
Affinity DataEC50: <1nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 573912BDBM573912(US11453697, Example 81 | US11453697, Example 90 | ...)
Affinity DataEC50: <1nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 573895BDBM573895(US11453697, Example 54 | 2-amino-9- [(5R,7R,8R,12a...)
Affinity DataEC50: <1nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 573933BDBM573933(US11453697, Example 117 | US11453697, Example 118 ...)
Affinity DataEC50:  1nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 573930BDBM573930(US11453697, Example 100 | US11453697, Example 101 ...)
Affinity DataEC50: <1nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 573937BDBM573937(US11453697, Example 121 | US11453697, Example 123)
Affinity DataEC50: <1nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 573939BDBM573939(US11453697, Example 124)
Affinity DataEC50: <1nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 573945BDBM573945(US11453697, Example 130 | 2-amino-9- [(2R,5S,7R,8R...)
Affinity DataEC50: <1nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 573942BDBM573942(US11453697, Example 127 | US11453697, Example 128 ...)
Affinity DataEC50: <1nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 573917BDBM573917(US11453697, Example 87 | US11453697, Example 88 | ...)
Affinity DataEC50: <1nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 573917BDBM573917(US11453697, Example 87 | US11453697, Example 88 | ...)
Affinity DataEC50: <1nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 573915BDBM573915(US11453697, Example 85 | 2-amino-9-[(5R,7R,8R,12aR...)
Affinity DataEC50: <1nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 573916BDBM573916(US11453697, Example 86 | 2-amino-9-[(2R,5S,7R,8R,1...)
Affinity DataEC50: <1nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 573923BDBM573923(US11453697, Example 93 | 2-amino-9- [(5R,7R,8R,12a...)
Affinity DataEC50: <1nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 573926BDBM573926(US11453697, Example 96 | 2-amino-9- [(5R,7R,8R,12a...)
Affinity DataEC50: <1nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 573927BDBM573927(US11453697, Example 97 | 2-amino-9-[(2R,5R,7R,8R,1...)
Affinity DataEC50: <1nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 573964BDBM573964(US11453697, Example 149 | 2-amino-9-[(5S,7R,8R,12a...)
Affinity DataEC50: <1nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 573966BDBM573966(US11453697, Example 151 | 2-amino-9-[(2R,5S,7R,8R,...)
Affinity DataEC50: <1nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 573842BDBM573842(US11453697, Example 6 | (5R,7R,8R,12aR,14R,15R,15a...)
Affinity DataEC50: <1nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 573848BDBM573848(US11453697, Example 12 | (5R,7R,8R,12aR,14R,15R,15...)
Affinity DataEC50: <1nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 573964BDBM573964(US11453697, Example 149 | 2-amino-9-[(5S,7R,8R,12a...)
Affinity DataEC50: <1nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 573971BDBM573971(US11453697, Example 247)
Affinity DataEC50: <1nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 573850BDBM573850(US11453697, Example 14 | 2-amino-9- [(5S,7R,8R,12a...)
Affinity DataEC50: <1nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 573856BDBM573856(US11453697, Example 20)
Affinity DataEC50: <1nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 573949BDBM573949(US11453697, Example 134 | US11453697, Example 136 ...)
Affinity DataEC50: <1nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 573954BDBM573954(US11453697, Example 139 | 2-amino-9-[(5S,7R,8R,12a...)
Affinity DataEC50: <1nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 573954BDBM573954(US11453697, Example 139 | 2-amino-9-[(5S,7R,8R,12a...)
Affinity DataEC50: <1nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 50509412BDBM50509412(CHEMBL4474321 | US11453697, Example 1)
Affinity DataEC50: <1nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 573959BDBM573959(US11453697, Example 144 | 2-amino-9- [(2R,5R,7R,8S...)
Affinity DataEC50: <1nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 573960BDBM573960(US11453697, Example 145 | 2-amino-9- [(5R,7R,8S,12...)
Affinity DataEC50: <1nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

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