Compile Data Set for Download or QSAR
Report error Found 517 Enz. Inhib. hit(s) with Target = 'Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial'
LigandChemical structure of BindingDB Monomer ID 50231814BDBM50231814(CHEMBL4078870 | US11725000, Compound 289)
Affinity DataEC50:  0.230nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing tBid assessed as reduction in apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50231814BDBM50231814(CHEMBL4078870 | US11725000, Compound 289)
Affinity DataEC50:  0.420nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50231783BDBM50231783(CHEMBL4078220 | US11725000, Compound 155)
Affinity DataEC50:  1.40nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details Article
PubMed
TargetSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial(Speckled leaf blotch fungus)
Fmc Stine Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50191588BDBM50191588(Antipiricullin | Fintrol | Antimycin A1 | antimyci...)
Affinity DataIC50: 2nMAssay Description:Inhibition of Septoria nodorum succinate dehydrogenase and Qi site of mitochondrial respiratory chain complex 3 by FMET2-3 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial(Speckled leaf blotch fungus)
Fmc Stine Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50411095BDBM50411095(CHEMBL439507)
Affinity DataIC50: 5nMAssay Description:Inhibition of Septoria nodorum succinate dehydrogenase and Qi site of mitochondrial respiratory chain complex 3 by FMET2-3 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 613053BDBM613053(US11725000, Compound 316)
Affinity DataEC50:  5.5nMAssay Description:In order to identify the target protein of tTC09 apoptosis inhibitors, we synthesized two sets of probes for target identification based on the SAR s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 613030BDBM613030(US11725000, Compound 292)
Affinity DataEC50:  5.5nMAssay Description:In order to identify the target protein of tTC09 apoptosis inhibitors, we synthesized two sets of probes for target identification based on the SAR s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 613062BDBM613062(US11725000, Compound 325)
Affinity DataEC50:  5.5nMAssay Description:In order to identify the target protein of tTC09 apoptosis inhibitors, we synthesized two sets of probes for target identification based on the SAR s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 613029BDBM613029(US11725000, Compound 291)
Affinity DataEC50:  5.5nMAssay Description:In order to identify the target protein of tTC09 apoptosis inhibitors, we synthesized two sets of probes for target identification based on the SAR s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 613061BDBM613061(US11725000, Compound 324)
Affinity DataEC50:  5.5nMAssay Description:In order to identify the target protein of tTC09 apoptosis inhibitors, we synthesized two sets of probes for target identification based on the SAR s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 613028BDBM613028(US11725000, Compound 290)
Affinity DataEC50:  5.5nMAssay Description:In order to identify the target protein of tTC09 apoptosis inhibitors, we synthesized two sets of probes for target identification based on the SAR s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 613034BDBM613034(US11725000, Compound 296)
Affinity DataEC50:  5.5nMAssay Description:In order to identify the target protein of tTC09 apoptosis inhibitors, we synthesized two sets of probes for target identification based on the SAR s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 613039BDBM613039(US11725000, Compound 301)
Affinity DataEC50:  5.5nMAssay Description:In order to identify the target protein of tTC09 apoptosis inhibitors, we synthesized two sets of probes for target identification based on the SAR s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 613071BDBM613071(US11725000, Compound 334)
Affinity DataEC50:  5.5nMAssay Description:In order to identify the target protein of tTC09 apoptosis inhibitors, we synthesized two sets of probes for target identification based on the SAR s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 613046BDBM613046(US11725000, Compound 309)
Affinity DataEC50:  5.5nMAssay Description:In order to identify the target protein of tTC09 apoptosis inhibitors, we synthesized two sets of probes for target identification based on the SAR s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 613011BDBM613011(US11725000, Compound 273)
Affinity DataEC50:  5.5nMAssay Description:In order to identify the target protein of tTC09 apoptosis inhibitors, we synthesized two sets of probes for target identification based on the SAR s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 613050BDBM613050(US11725000, Compound 313)
Affinity DataEC50:  5.5nMAssay Description:In order to identify the target protein of tTC09 apoptosis inhibitors, we synthesized two sets of probes for target identification based on the SAR s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 613047BDBM613047(US11725000, Compound 310)
Affinity DataEC50:  5.5nMAssay Description:In order to identify the target protein of tTC09 apoptosis inhibitors, we synthesized two sets of probes for target identification based on the SAR s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 612765BDBM612765(US11725000, Compound 27)
Affinity DataEC50:  13nMAssay Description:In order to identify the target protein of tTC09 apoptosis inhibitors, we synthesized two sets of probes for target identification based on the SAR s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 50231789BDBM50231789(CHEMBL4091379 | US11725000, Compound 127)
Affinity DataEC50:  25nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details Article
PubMed
TargetSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial(Speckled leaf blotch fungus)
Fmc Stine Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50411094BDBM50411094(CHEMBL379116)
Affinity DataIC50: 26nMAssay Description:Inhibition of Septoria nodorum succinate dehydrogenase and Qi site of mitochondrial respiratory chain complex 3 by FMET2-3 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial(Speckled leaf blotch fungus)
Fmc Stine Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50411096BDBM50411096(CHEMBL378123)
Affinity DataIC50: 26nMAssay Description:Inhibition of Septoria nodorum succinate dehydrogenase and Qi site of mitochondrial respiratory chain complex 3 by FMET2-3 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50231785BDBM50231785(CHEMBL4064603 | US11725000, Compound 152)
Affinity DataEC50:  27nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details Article
PubMed
TargetSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial(Speckled leaf blotch fungus)
Fmc Stine Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50411097BDBM50411097(CHEMBL379557)
Affinity DataIC50: 32nMAssay Description:Inhibition of Septoria nodorum succinate dehydrogenase and Qi site of mitochondrial respiratory chain complex 3 by FMET2-3 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 612761BDBM612761(US11725000, Compound 23)
Affinity DataEC50:  57nMAssay Description:In order to identify the target protein of tTC09 apoptosis inhibitors, we synthesized two sets of probes for target identification based on the SAR s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 50231795BDBM50231795(CHEMBL4070501 | US11725000, Compound 109)
Affinity DataEC50:  57nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 612770BDBM612770(US11725000, Compound 32)
Affinity DataEC50:  64nMAssay Description:In order to identify the target protein of tTC09 apoptosis inhibitors, we synthesized two sets of probes for target identification based on the SAR s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 612759BDBM612759(US11725000, Compound 21)
Affinity DataEC50:  66nMAssay Description:In order to identify the target protein of tTC09 apoptosis inhibitors, we synthesized two sets of probes for target identification based on the SAR s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 50231821BDBM50231821(CHEMBL4061878 | US11725000, Compound 106)
Affinity DataEC50:  66nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50231820BDBM50231820(CHEMBL4092330 | US11725000, Compound 113)
Affinity DataEC50:  69nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 612763BDBM612763(US11725000, Compound 25)
Affinity DataEC50:  69nMAssay Description:In order to identify the target protein of tTC09 apoptosis inhibitors, we synthesized two sets of probes for target identification based on the SAR s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 50231793BDBM50231793(CHEMBL4082074 | US11725000, Compound 110)
Affinity DataEC50:  94nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50231825BDBM50231825(CHEMBL4090123 | US11725000, Compound 26)
Affinity DataEC50:  94nMAssay Description:In order to identify the target protein of tTC09 apoptosis inhibitors, we synthesized two sets of probes for target identification based on the SAR s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 613037BDBM613037(US11725000, Compound 299)
Affinity DataEC50: <100nMAssay Description:In order to identify the target protein of tTC09 apoptosis inhibitors, we synthesized two sets of probes for target identification based on the SAR s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 613052BDBM613052(US11725000, Compound 315)
Affinity DataEC50: <100nMAssay Description:In order to identify the target protein of tTC09 apoptosis inhibitors, we synthesized two sets of probes for target identification based on the SAR s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 613036BDBM613036(US11725000, Compound 298)
Affinity DataEC50: <100nMAssay Description:In order to identify the target protein of tTC09 apoptosis inhibitors, we synthesized two sets of probes for target identification based on the SAR s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 613035BDBM613035(US11725000, Compound 297)
Affinity DataEC50: <100nMAssay Description:In order to identify the target protein of tTC09 apoptosis inhibitors, we synthesized two sets of probes for target identification based on the SAR s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 613042BDBM613042(US11725000, Compound 304)
Affinity DataEC50: <100nMAssay Description:In order to identify the target protein of tTC09 apoptosis inhibitors, we synthesized two sets of probes for target identification based on the SAR s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 613041BDBM613041(US11725000, Compound 303)
Affinity DataEC50: <100nMAssay Description:In order to identify the target protein of tTC09 apoptosis inhibitors, we synthesized two sets of probes for target identification based on the SAR s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 613013BDBM613013(US11725000, Compound 275)
Affinity DataEC50: <100nMAssay Description:In order to identify the target protein of tTC09 apoptosis inhibitors, we synthesized two sets of probes for target identification based on the SAR s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 613045BDBM613045(US11725000, Compound 308)
Affinity DataEC50: <100nMAssay Description:In order to identify the target protein of tTC09 apoptosis inhibitors, we synthesized two sets of probes for target identification based on the SAR s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 613012BDBM613012(US11725000, Compound 274)
Affinity DataEC50: <100nMAssay Description:In order to identify the target protein of tTC09 apoptosis inhibitors, we synthesized two sets of probes for target identification based on the SAR s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 613065BDBM613065(US11725000, Compound 328)
Affinity DataEC50: <100nMAssay Description:In order to identify the target protein of tTC09 apoptosis inhibitors, we synthesized two sets of probes for target identification based on the SAR s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 613049BDBM613049(US11725000, Compound 312)
Affinity DataEC50: <100nMAssay Description:In order to identify the target protein of tTC09 apoptosis inhibitors, we synthesized two sets of probes for target identification based on the SAR s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 50231809BDBM50231809(CHEMBL4070722 | US11725000, Compound 29)
Affinity DataEC50:  104nMAssay Description:In order to identify the target protein of tTC09 apoptosis inhibitors, we synthesized two sets of probes for target identification based on the SAR s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 612762BDBM612762(US11725000, Compound 24)
Affinity DataEC50:  110nMAssay Description:In order to identify the target protein of tTC09 apoptosis inhibitors, we synthesized two sets of probes for target identification based on the SAR s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 50231794BDBM50231794(CHEMBL4071549 | US11725000, Compound 112)
Affinity DataEC50:  110nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details Article
PubMed
TargetSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial(Speckled leaf blotch fungus)
Fmc Stine Research Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50411098BDBM50411098(CHEMBL377384)
Affinity DataIC50: 127nMAssay Description:Inhibition of Septoria nodorum succinate dehydrogenase and Qi site of mitochondrial respiratory chain complex 3 by FMET2-3 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50231817BDBM50231817(CHEMBL4086114 | US11725000, Compound 151)
Affinity DataEC50:  164nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50231787BDBM50231787(CHEMBL4093871 | US11725000, Compound 143)
Affinity DataEC50:  216nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details Article
PubMed
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