Compile Data Set for Download or QSAR
Report error Found 30 Enz. Inhib. hit(s) with Target = 'Threonine--tRNA ligase 1, cytoplasmic'
TargetThreonine--tRNA ligase 1, cytoplasmic(Human)
Trius Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50426188BDBM50426188(CHEMBL2311920)
Affinity DataKi:  1.20nMAssay Description:Binding affinity to human cytoplasmic ThrRS by coupled spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetThreonine--tRNA ligase 1, cytoplasmic(Human)
Trius Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50426182BDBM50426182(CHEMBL2311926)
Affinity DataKi:  1.80nMAssay Description:Binding affinity to human cytoplasmic ThrRS by coupled spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetThreonine--tRNA ligase 1, cytoplasmic(Human)
Trius Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50426184BDBM50426184(CHEMBL2311924)
Affinity DataKi:  3nMAssay Description:Binding affinity to human cytoplasmic ThrRS by coupled spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetThreonine--tRNA ligase 1, cytoplasmic(Human)
Trius Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50426190BDBM50426190(CHEMBL2311918)
Affinity DataKi:  3.30nMAssay Description:Binding affinity to human cytoplasmic ThrRS by coupled spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetThreonine--tRNA ligase 1, cytoplasmic(Human)
Trius Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50426183BDBM50426183(CHEMBL2311925)
Affinity DataKi:  4.10nMAssay Description:Binding affinity to human cytoplasmic ThrRS by coupled spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetThreonine--tRNA ligase 1, cytoplasmic(Human)
Trius Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50426181BDBM50426181(CHEMBL2311927)
Affinity DataKi:  5.20nMAssay Description:Binding affinity to human cytoplasmic ThrRS by coupled spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetThreonine--tRNA ligase 1, cytoplasmic(Human)
Trius Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50652792BDBM50652792(CHEMBL3752910)
Affinity DataKd:  5.30nMAssay Description:Binding affinity to human TARS incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetThreonine--tRNA ligase 1, cytoplasmic(Human)
Trius Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50426189BDBM50426189(CHEMBL2311919)
Affinity DataKi:  10nMAssay Description:Binding affinity to human cytoplasmic ThrRS by coupled spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetThreonine--tRNA ligase 1, cytoplasmic(Human)
Trius Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50426200BDBM50426200(CHEMBL2311917)
Affinity DataKi:  13nMAssay Description:Binding affinity to human cytoplasmic ThrRS by coupled spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetThreonine--tRNA ligase 1, cytoplasmic(Human)
Trius Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50366646BDBM50366646(CHEMBL1163068)
Affinity DataIC50: 15nMAssay Description:Inhibitory activity against cognate Staphylococcus aureus threonyl tRNA synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetThreonine--tRNA ligase 1, cytoplasmic(Human)
Trius Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50426194BDBM50426194(CHEMBL2316966)
Affinity DataKi:  32nMAssay Description:Binding affinity to human cytoplasmic ThrRS by coupled spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetThreonine--tRNA ligase 1, cytoplasmic(Human)
Trius Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50625969BDBM50625969(CHEMBL5405159)
Affinity DataKd:  49nMAssay Description:Inhibition of human cytosolic ThrRS assessed as dissociation constant by isothermal titration calorimetryMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetThreonine--tRNA ligase 1, cytoplasmic(Human)
Trius Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50652793BDBM50652793(CHEMBL5653589)
Affinity DataKd:  58nMAssay Description:Binding affinity to human TARS incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetThreonine--tRNA ligase 1, cytoplasmic(Human)
Trius Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50426187BDBM50426187(CHEMBL2311921)
Affinity DataKi:  72nMAssay Description:Binding affinity to human cytoplasmic ThrRS by coupled spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetThreonine--tRNA ligase 1, cytoplasmic(Human)
Trius Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50426180BDBM50426180(CHEMBL2311928)
Affinity DataKi:  91nMAssay Description:Binding affinity to human cytoplasmic ThrRS by coupled spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetThreonine--tRNA ligase 1, cytoplasmic(Human)
Trius Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50625967BDBM50625967(CHEMBL5430875)
Affinity DataKd:  115nMAssay Description:Inhibition of human cytosolic ThrRS assessed as dissociation constant by isothermal titration calorimetryMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetThreonine--tRNA ligase 1, cytoplasmic(Human)
Trius Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50625968BDBM50625968(CHEMBL5424310)
Affinity DataKd:  126nMAssay Description:Inhibition of human cytosolic ThrRS assessed as dissociation constant by isothermal titration calorimetryMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetThreonine--tRNA ligase 1, cytoplasmic(Human)
Trius Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50426197BDBM50426197(CHEMBL2316963)
Affinity DataKi:  399nMAssay Description:Binding affinity to human cytoplasmic ThrRS by coupled spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetThreonine--tRNA ligase 1, cytoplasmic(Human)
Trius Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50426186BDBM50426186(CHEMBL2311922)
Affinity DataKi:  463nMAssay Description:Binding affinity to human cytoplasmic ThrRS by coupled spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetThreonine--tRNA ligase 1, cytoplasmic(Human)
Trius Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50426193BDBM50426193(CHEMBL2316967)
Affinity DataKi:  601nMAssay Description:Binding affinity to human cytoplasmic ThrRS by coupled spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetThreonine--tRNA ligase 1, cytoplasmic(Human)
Trius Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50426198BDBM50426198(CHEMBL2316962)
Affinity DataKi:  935nMAssay Description:Binding affinity to human cytoplasmic ThrRS by coupled spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetThreonine--tRNA ligase 1, cytoplasmic(Human)
Trius Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50426179BDBM50426179(CHEMBL2311929)
Affinity DataKi:  1.52E+3nMAssay Description:Binding affinity to human cytoplasmic ThrRS by coupled spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetThreonine--tRNA ligase 1, cytoplasmic(Human)
Trius Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50426185BDBM50426185(CHEMBL2311923)
Affinity DataKi:  2.24E+3nMAssay Description:Binding affinity to human cytoplasmic ThrRS by coupled spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetThreonine--tRNA ligase 1, cytoplasmic(Human)
Trius Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50426178BDBM50426178(CHEMBL2316960)
Affinity DataKi:  5.82E+3nMAssay Description:Binding affinity to human cytoplasmic ThrRS by coupled spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetThreonine--tRNA ligase 1, cytoplasmic(Human)
Trius Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50426191BDBM50426191(CHEMBL2311916)
Affinity DataKi:  1.26E+4nMAssay Description:Binding affinity to human cytoplasmic ThrRS by coupled spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetThreonine--tRNA ligase 1, cytoplasmic(Human)
Trius Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50426199BDBM50426199(CHEMBL2316959)
Affinity DataKi:  3.68E+4nMAssay Description:Binding affinity to human cytoplasmic ThrRS by coupled spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetThreonine--tRNA ligase 1, cytoplasmic(Human)
Trius Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50426195BDBM50426195(CHEMBL2316965)
Affinity DataKi: >5.00E+4nMAssay Description:Binding affinity to human cytoplasmic ThrRS by coupled spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetThreonine--tRNA ligase 1, cytoplasmic(Human)
Trius Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50426196BDBM50426196(CHEMBL2316964)
Affinity DataKi: >5.00E+4nMAssay Description:Binding affinity to human cytoplasmic ThrRS by coupled spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetThreonine--tRNA ligase 1, cytoplasmic(Human)
Trius Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50426177BDBM50426177(CHEMBL2316961)
Affinity DataKi: >5.00E+4nMAssay Description:Binding affinity to human cytoplasmic ThrRS by coupled spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetThreonine--tRNA ligase 1, cytoplasmic(Human)
Trius Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50426192BDBM50426192(CHEMBL2316968)
Affinity DataKi: >5.00E+4nMAssay Description:Binding affinity to human cytoplasmic ThrRS by coupled spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed