Compile Data Set for Download or QSAR
Report error Found 33 Enz. Inhib. hit(s) with Target = 'Thyroid hormone receptor alpha/beta'
TargetThyroid hormone receptor alpha/beta(Human)
Bayer Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50477506BDBM50477506(CHEMBL392666)
Affinity DataEC50:  0.0600nMAssay Description:Agonist activity at THR in HepG2 cells by whole cell assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetThyroid hormone receptor alpha/beta(Human)
Bayer Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50477507BDBM50477507(CHEMBL248111)
Affinity DataEC50:  0.0800nMAssay Description:Agonist activity at THR in HepG2 cells by whole cell assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetThyroid hormone receptor alpha/beta(Human)
Bayer Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50163895BDBM50163895((S)-2-Amino-3-[4-(4-hydroxy-3-iodo-phenoxy)-3-iodo...)
Affinity DataEC50:  0.200nMAssay Description:Agonist activity towards thyroid hormone receptor expressed in human HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThyroid hormone receptor alpha/beta(Human)
Bayer Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50477505BDBM50477505(CHEMBL248515)
Affinity DataEC50:  0.300nMAssay Description:Agonist activity at THR in HepG2 cells by whole cell assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetThyroid hormone receptor alpha/beta(Human)
Bayer Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50163906BDBM50163906([4-(3-Isopropyl-1H-indol-5-yloxy)-3,5-bis-trifluor...)
Affinity DataEC50:  0.5nMAssay Description:Agonist activity towards thyroid hormone receptor expressed in human HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThyroid hormone receptor alpha/beta(Human)
Bayer Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50163901BDBM50163901(N-[3,5-Dibromo-4-(3-isopropyl-1H-indol-5-yloxy)-ph...)
Affinity DataEC50:  1.20nMAssay Description:Agonist activity towards thyroid hormone receptor expressed in human HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThyroid hormone receptor alpha/beta(Human)
Bayer Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50163897BDBM50163897(3-[4-(3-Isopropyl-1H-indol-5-yloxy)-3,5-bis-triflu...)
Affinity DataEC50:  2.60nMAssay Description:Agonist activity towards thyroid hormone receptor expressed in human HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThyroid hormone receptor alpha/beta(Human)
Bayer Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50163888BDBM50163888(N-[4-(3-Isopropyl-1H-indol-5-yloxy)-3,5-bis-triflu...)
Affinity DataEC50:  3nMAssay Description:Agonist activity towards thyroid hormone receptor expressed in human HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThyroid hormone receptor alpha/beta(Human)
Bayer Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50163900BDBM50163900((E)-3-[4-(3-Isopropyl-1H-indol-5-yloxy)-3,5-bis-tr...)
Affinity DataEC50:  3.20nMAssay Description:Agonist activity towards thyroid hormone receptor expressed in human HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThyroid hormone receptor alpha/beta(Human)
Bayer Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50163890BDBM50163890(N-[4-(3-Isopropyl-1H-indol-5-yloxy)-3,5-dimethyl-p...)
Affinity DataEC50:  4nMAssay Description:Agonist activity towards thyroid hormone receptor expressed in human HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThyroid hormone receptor alpha/beta(Human)
Bayer Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50163899BDBM50163899(N-[3,5-Dichloro-4-(3-isopropyl-1H-indol-5-yloxy)-p...)
Affinity DataEC50:  4nMAssay Description:Agonist activity towards thyroid hormone receptor expressed in human HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThyroid hormone receptor alpha/beta(Human)
Bayer Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50163898BDBM50163898(N-[3-Chloro-4-(3-isopropyl-1H-indol-5-yloxy)-5-met...)
Affinity DataEC50:  4nMAssay Description:Agonist activity towards thyroid hormone receptor expressed in human HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThyroid hormone receptor alpha/beta(Human)
Bayer Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50477508BDBM50477508(CHEMBL248315)
Affinity DataEC50:  5.10nMAssay Description:Agonist activity at THR in HepG2 cells by whole cell assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetThyroid hormone receptor alpha/beta(Human)
Bayer Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50477509BDBM50477509(CHEMBL395954)
Affinity DataEC50:  7nMAssay Description:Agonist activity at THR in HepG2 cells by whole cell assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetThyroid hormone receptor alpha/beta(Human)
Bayer Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50163896BDBM50163896(N-[4-(3-Isopropyl-1H-indol-5-yloxy)-3,5-divinyl-ph...)
Affinity DataEC50:  7.80nMAssay Description:Agonist activity towards thyroid hormone receptor expressed in human HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThyroid hormone receptor alpha/beta(Human)
Bayer Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50163889BDBM50163889(N-[3-Chloro-4-(3-isopropyl-1H-indol-5-yloxy)-5-met...)
Affinity DataEC50:  8nMAssay Description:Agonist activity towards thyroid hormone receptor expressed in human HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThyroid hormone receptor alpha/beta(Human)
Bayer Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50163892BDBM50163892(N-[3,5-Dimethyl-4-(3-pentyl-1H-indazol-5-yloxy)-ph...)
Affinity DataEC50:  8nMAssay Description:Agonist activity towards thyroid hormone receptor expressed in human HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThyroid hormone receptor alpha/beta(Human)
Bayer Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50163894BDBM50163894(N-{4-[3-(4-Fluoro-benzyl)-1H-indol-5-yloxy]-3,5-bi...)
Affinity DataEC50:  11nMAssay Description:Agonist activity towards thyroid hormone receptor expressed in human HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThyroid hormone receptor alpha/beta(Human)
Bayer Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50163902BDBM50163902(N-[3,5-Dichloro-4-(1H-indol-5-yloxy)-phenyl]-oxala...)
Affinity DataEC50:  15nMAssay Description:Agonist activity towards thyroid hormone receptor expressed in human HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThyroid hormone receptor alpha/beta(Human)
Bayer Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50163893BDBM50163893(N-[3,5-Dimethyl-4-(3-methyl-1H-indol-5-yloxy)-phen...)
Affinity DataEC50:  15nMAssay Description:Agonist activity towards thyroid hormone receptor expressed in human HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThyroid hormone receptor alpha/beta(Human)
Bayer Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50163904BDBM50163904(N-[4-(3-Isopropyl-1H-indol-5-ylmethyl)-3,5-dimethy...)
Affinity DataEC50:  18nMAssay Description:Agonist activity towards thyroid hormone receptor expressed in human HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThyroid hormone receptor alpha/beta(Human)
Bayer Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50477502BDBM50477502(CHEMBL247913)
Affinity DataEC50:  22nMAssay Description:Agonist activity at THR in HepG2 cells by whole cell assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetThyroid hormone receptor alpha/beta(Human)
Bayer Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50163887BDBM50163887(N-[4-(1H-Indol-5-yloxy)-3,5-bis-trifluoromethyl-ph...)
Affinity DataEC50:  23nMAssay Description:Agonist activity towards thyroid hormone receptor expressed in human HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThyroid hormone receptor alpha/beta(Human)
Bayer Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50477501BDBM50477501(CHEMBL245462)
Affinity DataEC50:  70nMAssay Description:Agonist activity at THR in HepG2 cells by whole cell assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetThyroid hormone receptor alpha/beta(Human)
Bayer Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50163905BDBM50163905(N-[4-(1H-Indol-5-yloxy)-3,5-dimethyl-phenyl]-oxala...)
Affinity DataEC50:  72nMAssay Description:Agonist activity towards thyroid hormone receptor expressed in human HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThyroid hormone receptor alpha/beta(Human)
Bayer Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50477500BDBM50477500(CHEMBL248314)
Affinity DataEC50:  110nMAssay Description:Agonist activity at THR in HepG2 cells by whole cell assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetThyroid hormone receptor alpha/beta(Human)
Bayer Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50163891BDBM50163891(N-{4-[3-(4-Fluoro-phenyl)-1H-indol-5-yloxy]-3,5-bi...)
Affinity DataEC50:  115nMAssay Description:Agonist activity towards thyroid hormone receptor expressed in human HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThyroid hormone receptor alpha/beta(Human)
Bayer Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50477499BDBM50477499(CHEMBL247912)
Affinity DataEC50:  210nMAssay Description:Agonist activity at THR in HepG2 cells by whole cell assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetThyroid hormone receptor alpha/beta(Human)
Bayer Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50163903BDBM50163903(N-{4-[3-(4-Fluoro-phenoxy)-1H-indol-5-yloxy]-3,5-b...)
Affinity DataEC50:  495nMAssay Description:Agonist activity towards thyroid hormone receptor expressed in human HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThyroid hormone receptor alpha/beta(Human)
Bayer Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50477503BDBM50477503(CHEMBL245508)
Affinity DataEC50:  1.00E+3nMAssay Description:Agonist activity at THR in HepG2 cells by whole cell assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetThyroid hormone receptor alpha/beta(Human)
Bayer Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50477504BDBM50477504(CHEMBL393914)
Affinity DataEC50:  1.00E+3nMAssay Description:Agonist activity at THR in HepG2 cells by whole cell assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetThyroid hormone receptor alpha/beta(Human)
Bayer Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50477498BDBM50477498(CHEMBL245504)
Affinity DataEC50:  1.00E+3nMAssay Description:Agonist activity at THR in HepG2 cells by whole cell assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetThyroid hormone receptor alpha/beta(Human)
Bayer Healthcare

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50508127BDBM50508127(CHEMBL4449687)
Affinity DataIC50: 3.24E+4nMAssay Description:Antagonist activity at thyroid hormone receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed