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Report error Found 24 Enz. Inhib. hit(s) with Target = 'Transcription initiation factor IIA subunit 1'
TargetTranscription initiation factor IIA subunit 1(Human)
The Medicines Company (Leipzig)

US Patent
LigandChemical structure of BindingDB Monomer ID 108110BDBM108110(US8598206, Table 6, 19)
Affinity DataKi:  240nMAssay Description:Inhibition of human FIIa was determined by the method described in [0092]-[0098] using human alpha-thrombin from Enzyme Research Laboratories at 0.1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2014
Entry Details
US Patent

TargetTranscription initiation factor IIA subunit 1(Human)
The Medicines Company (Leipzig)

US Patent
LigandChemical structure of BindingDB Monomer ID 108097BDBM108097(US8598206, Table 6, 6)
Affinity DataKi:  800nMAssay Description:Inhibition of human FIIa was determined by the method described in [0092]-[0098] using human alpha-thrombin from Enzyme Research Laboratories at 0.1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2014
Entry Details
US Patent

TargetTranscription initiation factor IIA subunit 1(Human)
The Medicines Company (Leipzig)

US Patent
LigandChemical structure of BindingDB Monomer ID 108116BDBM108116(US8598206, Table 6, 3)
Affinity DataKi:  920nMAssay Description:Inhibition of human t-PA was determined by the method described in [0092]-[0098] using recombinant human tissue-type plasminogen activator (Actilyse&...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2014
Entry Details
US Patent

TargetTranscription initiation factor IIA subunit 1(Human)
The Medicines Company (Leipzig)

US Patent
LigandChemical structure of BindingDB Monomer ID 108117BDBM108117(US8598206, Table 6, 2)
Affinity DataKi:  1.20E+3nMAssay Description:Inhibition of human FIIa was determined by the method described in [0092]-[0098] using human alpha-thrombin from Enzyme Research Laboratories at 0.1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2014
Entry Details
US Patent

TargetTranscription initiation factor IIA subunit 1(Human)
The Medicines Company (Leipzig)

US Patent
LigandChemical structure of BindingDB Monomer ID 108111BDBM108111(US8598206, Table 6, 20)
Affinity DataKi:  1.70E+3nMAssay Description:Inhibition of human FIIa was determined by the method described in [0092]-[0098] using human alpha-thrombin from Enzyme Research Laboratories at 0.1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2014
Entry Details
US Patent

TargetTranscription initiation factor IIA subunit 1(Human)
The Medicines Company (Leipzig)

US Patent
LigandChemical structure of BindingDB Monomer ID 108115BDBM108115(US8598206, Table 6, 24)
Affinity DataKi:  3.60E+3nMAssay Description:Inhibition of human FIIa was determined by the method described in [0092]-[0098] using human alpha-thrombin from Enzyme Research Laboratories at 0.1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2014
Entry Details
US Patent

TargetTranscription initiation factor IIA subunit 1(Human)
The Medicines Company (Leipzig)

US Patent
LigandChemical structure of BindingDB Monomer ID 47177BDBM47177(BDBM108100 | US8598206, Table 6, 9)
Affinity DataKi:  3.80E+3nMAssay Description:Inhibition of human FIIa was determined by the method described in [0092]-[0098] using human alpha-thrombin from Enzyme Research Laboratories at 0.1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2014
Entry Details
US Patent

TargetTranscription initiation factor IIA subunit 1(Human)
The Medicines Company (Leipzig)

US Patent
LigandChemical structure of BindingDB Monomer ID 47178BDBM47178(US8598206, Table 6, 12 | BDBM108103)
Affinity DataKi:  3.90E+3nMAssay Description:Inhibition of human FIIa was determined by the method described in [0092]-[0098] using human alpha-thrombin from Enzyme Research Laboratories at 0.1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2014
Entry Details
US Patent

TargetTranscription initiation factor IIA subunit 1(Human)
The Medicines Company (Leipzig)

US Patent
LigandChemical structure of BindingDB Monomer ID 108101BDBM108101(US8598206, Table 6, 10)
Affinity DataKi:  4.20E+3nMAssay Description:Inhibition of human FIIa was determined by the method described in [0092]-[0098] using human alpha-thrombin from Enzyme Research Laboratories at 0.1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2014
Entry Details
US Patent

TargetTranscription initiation factor IIA subunit 1(Human)
The Medicines Company (Leipzig)

US Patent
LigandChemical structure of BindingDB Monomer ID 108095BDBM108095(US8598206, Table 6, 4)
Affinity DataKi:  4.40E+3nMAssay Description:Inhibition of human FIIa was determined by the method described in [0092]-[0098] using human alpha-thrombin from Enzyme Research Laboratories at 0.1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2014
Entry Details
US Patent

TargetTranscription initiation factor IIA subunit 1(Human)
The Medicines Company (Leipzig)

US Patent
LigandChemical structure of BindingDB Monomer ID 108102BDBM108102(US8598206, Table 6, 11)
Affinity DataKi:  4.50E+3nMAssay Description:Inhibition of human FIIa was determined by the method described in [0092]-[0098] using human alpha-thrombin from Enzyme Research Laboratories at 0.1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2014
Entry Details
US Patent

TargetTranscription initiation factor IIA subunit 1(Human)
The Medicines Company (Leipzig)

US Patent
LigandChemical structure of BindingDB Monomer ID 108118BDBM108118(US8598206, Table 6, 1)
Affinity DataKi:  4.70E+3nMAssay Description:Inhibition of human FIIa was determined by the method described in [0092]-[0098] using human alpha-thrombin from Enzyme Research Laboratories at 0.1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2014
Entry Details
US Patent

TargetTranscription initiation factor IIA subunit 1(Human)
The Medicines Company (Leipzig)

US Patent
LigandChemical structure of BindingDB Monomer ID 108105BDBM108105(US8598206, Table 6, 14)
Affinity DataKi:  4.80E+3nMAssay Description:Inhibition of human FIIa was determined by the method described in [0092]-[0098] using human alpha-thrombin from Enzyme Research Laboratories at 0.1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2014
Entry Details
US Patent

TargetTranscription initiation factor IIA subunit 1(Human)
The Medicines Company (Leipzig)

US Patent
LigandChemical structure of BindingDB Monomer ID 108108BDBM108108(US8598206, 123 | US8598206, 117)
Affinity DataKi:  4.90E+3nMAssay Description:Inhibition of human FIIa was determined by the method described in [0092]-[0098] using human alpha-thrombin from Enzyme Research Laboratories at 0.1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2014
Entry Details
US Patent

TargetTranscription initiation factor IIA subunit 1(Human)
The Medicines Company (Leipzig)

US Patent
LigandChemical structure of BindingDB Monomer ID 108108BDBM108108(US8598206, 123 | US8598206, 117)
Affinity DataKi:  4.90E+3nMAssay Description:Inhibition of human FIIa was determined by the method described in [0092]-[0098] using human alpha-thrombin from Enzyme Research Laboratories at 0.1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2014
Entry Details
US Patent

TargetTranscription initiation factor IIA subunit 1(Human)
The Medicines Company (Leipzig)

US Patent
LigandChemical structure of BindingDB Monomer ID 108106BDBM108106(US8598206, Table 6, 15)
Affinity DataKi:  5.50E+3nMAssay Description:Inhibition of human FIIa was determined by the method described in [0092]-[0098] using human alpha-thrombin from Enzyme Research Laboratories at 0.1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2014
Entry Details
US Patent

TargetTranscription initiation factor IIA subunit 1(Human)
The Medicines Company (Leipzig)

US Patent
LigandChemical structure of BindingDB Monomer ID 108099BDBM108099(US8598206, Table 6, 8)
Affinity DataKi:  5.60E+3nMAssay Description:Inhibition of human FIIa was determined by the method described in [0092]-[0098] using human alpha-thrombin from Enzyme Research Laboratories at 0.1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2014
Entry Details
US Patent

TargetTranscription initiation factor IIA subunit 1(Human)
The Medicines Company (Leipzig)

US Patent
LigandChemical structure of BindingDB Monomer ID 108096BDBM108096(US8598206, Table 6, 5)
Affinity DataKi:  8.00E+3nMAssay Description:Inhibition of human FIIa was determined by the method described in [0092]-[0098] using human alpha-thrombin from Enzyme Research Laboratories at 0.1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2014
Entry Details
US Patent

TargetTranscription initiation factor IIA subunit 1(Human)
The Medicines Company (Leipzig)

US Patent
LigandChemical structure of BindingDB Monomer ID 108098BDBM108098(US8598206, Table 6, 7)
Affinity DataKi:  8.50E+3nMAssay Description:Inhibition of human FIIa was determined by the method described in [0092]-[0098] using human alpha-thrombin from Enzyme Research Laboratories at 0.1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2014
Entry Details
US Patent

TargetTranscription initiation factor IIA subunit 1(Human)
The Medicines Company (Leipzig)

US Patent
LigandChemical structure of BindingDB Monomer ID 108112BDBM108112(US8598206, Table 6, 21)
Affinity DataKi:  9.00E+3nMAssay Description:Inhibition of human FIIa was determined by the method described in [0092]-[0098] using human alpha-thrombin from Enzyme Research Laboratories at 0.1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2014
Entry Details
US Patent

TargetTranscription initiation factor IIA subunit 1(Human)
The Medicines Company (Leipzig)

US Patent
LigandChemical structure of BindingDB Monomer ID 108107BDBM108107(US8598206, Table 6, 16)
Affinity DataKi:  1.30E+4nMAssay Description:Inhibition of human FIIa was determined by the method described in [0092]-[0098] using human alpha-thrombin from Enzyme Research Laboratories at 0.1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2014
Entry Details
US Patent

TargetTranscription initiation factor IIA subunit 1(Human)
The Medicines Company (Leipzig)

US Patent
LigandChemical structure of BindingDB Monomer ID 108109BDBM108109(US8598206, 122 | US8598206, 118)
Affinity DataKi:  1.30E+4nMAssay Description:Inhibition of human FIIa was determined by the method described in [0092]-[0098] using human alpha-thrombin from Enzyme Research Laboratories at 0.1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2014
Entry Details
US Patent

TargetTranscription initiation factor IIA subunit 1(Human)
The Medicines Company (Leipzig)

US Patent
LigandChemical structure of BindingDB Monomer ID 108109BDBM108109(US8598206, 122 | US8598206, 118)
Affinity DataKi:  1.30E+4nMAssay Description:Inhibition of human FIIa was determined by the method described in [0092]-[0098] using human alpha-thrombin from Enzyme Research Laboratories at 0.1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2014
Entry Details
US Patent

TargetTranscription initiation factor IIA subunit 1(Human)
The Medicines Company (Leipzig)

US Patent
LigandChemical structure of BindingDB Monomer ID 108104BDBM108104(US8598206, Table 6, 13)
Affinity DataKi:  1.30E+4nMAssay Description:Inhibition of human FIIa was determined by the method described in [0092]-[0098] using human alpha-thrombin from Enzyme Research Laboratories at 0.1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2014
Entry Details
US Patent